| Compound ID |
Compound Name |
Compound Formula |
|
CP0148987
|
(S)-6-(2-(pyrimidin-5-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C16H14N4
|
1
|
| 1 |
EC50 = 0.4 nM
|
|
|
|
CP0040622
|
6-(5-fluoro-2-(pyrimidin-5-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C16H13FN4
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
|
CP0094131
|
(S)-6-(2-(pyridin-3-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C17H15N3
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
|
CP0316893
|
(S)-2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)phenyl)oxazole
Show/Hide
|
C15H13N3O
|
1
|
| 1 |
EC50 = 2 nM
|
|
|
|
CP0174628
|
(S)-2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)phenyl)thiazole
Show/Hide
|
C15H13N3S
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0234407
|
6-(5-fluoro-2-(1H-pyrazol-5-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C15H13FN4
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0374408
|
2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)-4-fluorophenyl)oxazole
Show/Hide
|
C15H12FN3O
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0432099
|
4-[1-(1H-imidazol-2-yl)-2,3-dihydro-1H-inden-4-yl]-5-methyl-1H-pyrazole
Show/Hide
|
C16H16N4
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0086900
|
(S)-N-(2'-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)biphenyl-3-yl)methanesulfonamide
Show/Hide
|
C19H19N3O2S
|
1
|
| 1 |
EC50 = 4 nM
|
|
|
|
CP0070312
|
(S)-6-(2-(1H-pyrazol-1-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C15H14N4
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0278671
|
6-(5-fluoro-2-(1H-pyrazol-1-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C15H13FN4
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0265448
|
(S)-6-(2-(1-methyl-1H-pyrazol-4-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C16H16N4
|
1
|
| 1 |
EC50 = 9 nM
|
|
|
|
CP0095298
|
(R)-3-fluoro-1-((5-fluoro-1-(1H-imidazol-2-yl)-2,3-dihydro-1H-inden-4-yl)methyl)-1H-pyrazole
Show/Hide
|
C16H14F2N4
|
1
|
| 1 |
EC50 = 9 nM
|
|
|
|
CP0039841
|
ABT-866
Show/Hide
|
C12H15N3O2S
|
1
|
| 1 |
EC50 = 9 nM
|
|
|
|
CP0439501
|
6-(2-(difluoromethoxy)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C13H12F2N2O
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0070307
|
(S)-6-(biphenyl-2-yl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C18H16N2
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0094133
|
(S)-2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)phenyl)-N-methylethanesulfonamide
Show/Hide
|
C15H19N3O2S
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0399603
|
2-[4-(1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-yl]-1H-imidazole
Show/Hide
|
C15H14N4
|
1
|
| 1 |
EC50 = 14 nM
|
|
|
|
CP0308471
|
6-(4-fluoro-2-(1H-pyrazol-5-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C15H13FN4
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
|
CP0418460
|
3-fluoro-1-((2,3-dihydro-1-(1H-imidazol-2-yl)-1H-inden-4-yl)methyl)-1H-pyrazole
Show/Hide
|
C16H15FN4
|
1
|
| 1 |
EC50 = 17 nM
|
|
|
|
CP0387538
|
6-(2-chlorophenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C12H11ClN2
|
1
|
| 1 |
EC50 = 19 nM
|
|
|
|
CP0040617
|
6-(4-fluoro-2-(pyrimidin-5-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C16H13FN4
|
1
|
| 1 |
EC50 = 19 nM
|
|
|
|
CP0280468
|
(S)-2'-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)-N-methylbiphenyl-3-carboxamide
Show/Hide
|
C20H19N3O
|
1
|
| 1 |
EC50 = 19 nM
|
|
|
|
CP0381835
|
6-(2-methoxyphenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C13H14N2O
|
1
|
| 1 |
EC50 = 22 nM
|
|
|
|
CP0412857
|
N-[6-chloro-3-(4,5-dihydro-1H-imidazol-2-ylmethoxy)-2-methylphenyl]methanesulfonamide
Show/Hide
|
C12H16ClN3O3S
|
1
|
| 1 |
EC50 = 25 nM
|
|
|
|
CP0148986
|
(R)-2-(5-chloro-4-(methoxymethyl)-2,3-dihydro-1H-inden-1-yl)-1H-imidazole
Show/Hide
|
C14H15ClN2O
|
2
|
| 1 |
EC50 = 27 nM
|
|
|
| 2 |
EC50 = 31 nM
|
|
|
|
CP0152026
|
6-(4-fluoro-2-(1H-pyrazol-1-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C15H13FN4
|
1
|
| 1 |
EC50 = 27 nM
|
|
|
|
CP0538605
|
(R)-1-((1-(1H-imidazol-2-yl)-2,3-dihydro-1H-inden-4-yl)methyl)-1H-pyrazole
Show/Hide
|
C16H16N4
|
1
|
| 1 |
EC50 = 32 nM
|
|
|
|
CP0386334
|
N-[1-(1H-imidazol-2-yl)-2,3-dihydro-1H-inden-4-yl]ethanesulfonamide
Show/Hide
|
C14H17N3O2S
|
1
|
| 1 |
EC50 = 32 nM
|
|
|
|
CP0432098
|
2-(4-methoxy-2,3-dihydro-1H-inden-1-yl)-1H-imidazole
Show/Hide
|
C13H14N2O
|
1
|
| 1 |
EC50 = 32 nM
|
|
|
|
CP0374403
|
2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)-5-fluorophenyl)oxazole
Show/Hide
|
C15H12FN3O
|
1
|
| 1 |
EC50 = 33 nM
|
|
|
|
CP0412856
|
N-[1-(1H-imidazol-2-yl)-5-methyl-2,3-dihydro-1H-inden-4-yl]methanesulfonamide
Show/Hide
|
C14H17N3O2S
|
1
|
| 1 |
EC50 = 33 nM
|
|
|
|
CP0485107
|
(R)-2-(4-(methoxymethyl)-2,3-dihydro-1H-inden-1-yl)-1H-imidazole
Show/Hide
|
C14H16N2O
|
1
|
| 1 |
EC50 = 37 nM
|
|
|
|
CP0443477
|
6-(2-fluorophenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C12H11FN2
|
1
|
| 1 |
EC50 = 42 nM
|
|
|
|
CP0162054
|
N-[2-chloro-5-(1H-imidazol-2-yl)-5,6,7,8-tetrahydronaphthalen-1-yl]methanesulfonamide
Show/Hide
|
C14H16ClN3O2S
|
1
|
| 1 |
EC50 = 43 nM
|
|
|
|
CP0070621
|
2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)benzonitrile
Show/Hide
|
C13H11N3
|
1
|
| 1 |
EC50 = 51 nM
|
|
|
|
CP0174601
|
(S)-2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)benzonitrile
Show/Hide
|
C13H11N3
|
1
|
| 1 |
EC50 = 51 nM
|
|
|
|
CP0386331
|
2-[4-(1H-pyrazol-5-yl)-2,3-dihydro-1H-inden-1-yl]-1H-imidazole
Show/Hide
|
C15H14N4
|
1
|
| 1 |
EC50 = 52 nM
|
|
|
|
CP0485108
|
2-(6-fluoro-2,3-dihydro-4-(methoxymethyl)-1H-inden-1-yl)-1H-imidazole
Show/Hide
|
C14H15FN2O
|
1
|
| 1 |
EC50 = 59 nM
|
|
|
|
CP0297367
|
6-(2-fluoro-6-(pyrimidin-5-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C16H13FN4
|
1
|
| 1 |
EC50 = 62 nM
|
|
|
|
CP0401084
|
2-(4-(ethoxymethyl)-2,3-dihydro-1H-inden-1-yl)-1H-imidazole
Show/Hide
|
C15H18N2O
|
1
|
| 1 |
EC50 = 62 nM
|
|
|
|
CP0485130
|
(R)-2-(5-fluoro-4-(methoxymethyl)-2,3-dihydro-1H-inden-1-yl)-1H-imidazole
Show/Hide
|
C14H15FN2O
|
1
|
| 1 |
EC50 = 62 nM
|
|
|
|
CP0386335
|
N-[1-(1H-imidazol-2-yl)-2,3-dihydro-1H-inden-4-yl]methanesulfonamide
Show/Hide
|
C13H15N3O2S
|
1
|
| 1 |
EC50 = 70 nM
|
|
|
|
CP0386341
|
2-(5-chloro-4-(1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-yl)-1H-imidazole
Show/Hide
|
C15H13ClN4
|
1
|
| 1 |
EC50 = 78 nM
|
|
|
|
CP0307853
|
(S)-6-(2-(pyridin-4-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C17H15N3
|
1
|
| 1 |
EC50 = 81 nM
|
|
|
|
CP0497555
|
6-(2-(methoxymethyl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C14H16N2O
|
1
|
| 1 |
EC50 = 82 nM
|
|
|
|
CP0375054
|
2-(2,3-dihydro-4-((methylsulfonyl)methyl)-1H-inden-1-yl)-1H-imidazole
Show/Hide
|
C14H16N2O2S
|
1
|
| 1 |
EC50 = 84 nM
|
|
|
|
CP0375055
|
1-((2,3-dihydro-1-(1H-imidazol-2-yl)-1H-inden-4-yl)methyl)-1H-1,2,3-triazole
Show/Hide
|
C15H15N5
|
1
|
| 1 |
EC50 = 90 nM
|
|
|
|
CP0094129
|
(R)-2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)phenyl)oxazole
Show/Hide
|
C15H13N3O
|
1
|
| 1 |
EC50 = 92 nM
|
|
|
|
CP0485131
|
(R)-5-((1-(1H-imidazol-2-yl)-2,3-dihydro-1H-inden-4-yl)methyl)-3-methyl-1,2,4-oxadiazole
Show/Hide
|
C16H16N4O
|
1
|
| 1 |
EC50 = 111 nM
|
|
|
|
CP0433560
|
4-[1-(1H-imidazol-2-yl)-2,3-dihydro-1H-inden-4-yl]-5-methyl-1,2-oxazole
Show/Hide
|
C16H15N3O
|
1
|
| 1 |
EC50 = 111 nM
|
|
|
|
CP0388057
|
6-(2-methoxyphenyl)-4,5,6,7-tetrahydro-1H-benzo[d]imidazole
Show/Hide
|
C14H16N2O
|
1
|
| 1 |
EC50 = 144 nM
|
|
|
|
CP0433564
|
2-(4-methoxy-5-methyl-2,3-dihydro-1H-inden-1-yl)-1H-imidazole
Show/Hide
|
C14H16N2O
|
1
|
| 1 |
EC50 = 167 nM
|
|
|
|
CP0522404
|
2-(2,3-dihydro-4-(2-methoxyethyl)-1H-inden-1-yl)-1H-imidazole
Show/Hide
|
C15H18N2O
|
1
|
| 1 |
EC50 = 168 nM
|
|
|
|
CP0394388
|
2-[1-(1H-imidazol-2-yl)-2,3-dihydro-1H-inden-4-yl]-1,3-oxazole
Show/Hide
|
C15H13N3O
|
1
|
| 1 |
EC50 = 170 nM
|
|
|
|
CP0509153
|
2,2,2-trifluoro-N-((2,3-dihydro-1-(1H-imidazol-2-yl)-1H-inden-4-yl)methyl)ethanamine
Show/Hide
|
C15H16F3N3
|
1
|
| 1 |
EC50 = 195 nM
|
|
|
|
CP0443475
|
6-(2-chlorophenyl)-4,5,6,7-tetrahydro-1H-benzo[d]imidazole
Show/Hide
|
C13H13ClN2
|
1
|
| 1 |
EC50 = 276 nM
|
|
|
|
CP0412855
|
5-[1-(1H-imidazol-2-yl)-2,3-dihydro-1H-inden-4-yl]-1-methylpyrazole
Show/Hide
|
C16H16N4
|
1
|
| 1 |
EC50 = 278 nM
|
|
|
|
CP0386339
|
2-[5-chloro-4-(1H-pyrazol-5-yl)-2,3-dihydro-1H-inden-1-yl]-1H-imidazole
Show/Hide
|
C15H13ClN4
|
1
|
| 1 |
EC50 = 322 nM
|
|
|
|
CP0439491
|
2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)benzamide
Show/Hide
|
C13H13N3O
|
1
|
| 1 |
EC50 = 371 nM
|
|
|
|
CP0394382
|
2-(1,2,3,4-tetrahydronaphthalen-1-yl)-1H-imidazole
Show/Hide
|
C13H14N2
|
1
|
| 1 |
EC50 = 385 nM
|
|
|
|
CP0412860
|
2-[1-(1H-imidazol-2-yl)-2,3-dihydro-1H-inden-4-yl]-1,3-thiazole
Show/Hide
|
C15H13N3S
|
1
|
| 1 |
EC50 = 426 nM
|
|
|
|
CP0386328
|
2-(5-chloro-4-methoxy-2,3-dihydro-1H-inden-1-yl)-1H-imidazole
Show/Hide
|
C13H13ClN2O
|
1
|
| 1 |
EC50 = 451 nM
|
|
|
|
CP0394386
|
2-(2,3-dihydro-1H-inden-1-yl)-1H-imidazole
Show/Hide
|
C12H12N2
|
1
|
| 1 |
EC50 = 473 nM
|
|
|
|
CP0431172
|
6-(3-chlorophenyl)-4,5,6,7-tetrahydro-1H-benzo[d]imidazole
Show/Hide
|
C13H13ClN2
|
1
|
| 1 |
EC50 = 514 nM
|
|
|
|
CP0427948
|
6-(3-methoxyphenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C13H14N2O
|
1
|
| 1 |
EC50 = 578 nM
|
|
|
|
CP0494558
|
2-(4-fluoro-2,3-dihydro-7-(methoxymethyl)-1H-inden-3-yl)-1H-imidazole
Show/Hide
|
C14H15FN2O
|
1
|
| 1 |
EC50 = 658 nM
|
|
|
|
CP0387536
|
6-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine
Show/Hide
|
C13H14N2
|
1
|
| 1 |
EC50 = 721 nM
|
|
|
|
CP0443384
|
2-(4-((3,3-difluoroazetidin-1-yl)methyl)-2,3-dihydro-1H-inden-1-yl)-1H-imidazole
Show/Hide
|
C16H17F2N3
|
1
|
| 1 |
EC50 = 879 nM
|
|
|
|
CP0443525
|
6-(4-methoxyphenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C13H14N2O
|
1
|
| 1 |
EC50 = 939 nM
|
|
|
|
CP0428546
|
6-(3-methoxyphenyl)-4,5,6,7-tetrahydro-1H-benzo[d]imidazole
Show/Hide
|
C14H16N2O
|
1
|
| 1 |
EC50 = 1050 nM
|
|
|
|
CP0394385
|
2-[1-(1H-imidazol-2-yl)-2,3-dihydro-1H-inden-4-yl]pyridine
Show/Hide
|
C17H15N3
|
1
|
| 1 |
EC50 = 1150 nM
|
|
|
|
CP0386402
|
N-[1-(1H-imidazol-2-yl)-2,3-dihydro-1H-inden-4-yl]propane-1-sulfonamide
Show/Hide
|
C15H19N3O2S
|
1
|
| 1 |
EC50 = 1340 nM
|
|
|
|
CP0372418
|
2-(2,3-dihydro-1H-inden-2-yl)-1H-imidazole
Show/Hide
|
C12H12N2
|
1
|
| 1 |
EC50 = 1650 nM
|
|
|
|
CP0394391
|
3-[1-(1H-imidazol-2-yl)-2,3-dihydro-1H-inden-4-yl]pyridine
Show/Hide
|
C17H15N3
|
1
|
| 1 |
EC50 = 2060 nM
|
|
|
|
CP0386337
|
1-(1H-imidazol-2-yl)-N-methyl-2,3-dihydro-1H-indene-4-carboxamide
Show/Hide
|
C14H15N3O
|
1
|
| 1 |
EC50 = 2200 nM
|
|
|
|
CP0388099
|
6-(4-chlorophenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C12H11ClN2
|
1
|
| 1 |
EC50 = 3460 nM
|
|
|
|
CP0372416
|
6-(4-methoxyphenyl)-4,5,6,7-tetrahydro-1H-benzo[d]imidazole
Show/Hide
|
C14H16N2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0387537
|
6-(4-chlorophenyl)-4,5,6,7-tetrahydro-1H-benzo[d]imidazole
Show/Hide
|
C13H13ClN2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0412854
|
3-[1-(1H-imidazol-2-yl)-2,3-dihydro-1H-inden-4-yl]-1-methylpyrazole
Show/Hide
|
C16H16N4
|
1
|
| 1 |
EC50 > 1300 nM
|
|
|
|
CP0412851
|
4-[1-(1H-imidazol-2-yl)-2,3-dihydro-1H-inden-4-yl]-1-methylpyrazole
Show/Hide
|
C16H16N4
|
1
|
| 1 |
EC50 > 2900 nM
|
|
|
|
CP0041613
|
Anapriline
Show/Hide
|
C16H21NO2
|
2
|
| 1 |
EC50 > 5011.87 nM
|
|
|
| 2 |
IC50 > 5011.87 nM
|
|
|
|
CP0066236
|
1-(dimethylamino)-3-[(2-methyl-1H-1,2-benzazaborinin-8-yl)oxy]propan-2-ol
Show/Hide
|
C14H21BN2O2
|
2
|
| 1 |
EC50 > 5011.87 nM
|
|
|
| 2 |
IC50 > 5011.87 nM
|
|
|
|
CP0366351
|
1-(dimethylamino)-3-[(2-methyl-1H-1,2-benzazaborinin-5-yl)oxy]propan-2-ol
Show/Hide
|
C14H21BN2O2
|
2
|
| 1 |
EC50 > 5011.87 nM
|
|
|
| 2 |
IC50 > 5011.87 nM
|
|
|
|
CP0381815
|
3-[4-[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazine-1-carbonyl]triazol-1-yl]-7-(diethylamino)chromen-2-one
Show/Hide
|
C30H33N9O5
|
2
|
| 1 |
IC50 = 0.6 nM
|
|
|
| 2 |
Ki = 0.3 nM
|
|
|
|
CP0072943
|
3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphenyl)amino]phenol;methanesulfonic acid
Show/Hide
|
C17H19N3O
|
3
|
| 1 |
IC50 = 1.1 nM
|
|
|
| 2 |
Ki = 0.6 nM
|
|
|
| 3 |
Ki = 12 nM
|
|
|
|
CP0381526
|
3-[4-[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazine-1-carbonyl]triazol-1-yl]-7-hydroxychromen-2-one
Show/Hide
|
C26H24N8O6
|
2
|
| 1 |
IC50 = 2.5 nM
|
|
|
| 2 |
Ki = 1.3 nM
|
|
|
|
CP0415132
|
3-[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazine-1-carbonyl]-7-hydroxychromen-2-one
Show/Hide
|
C24H23N5O6
|
2
|
| 1 |
IC50 = 3.9 nM
|
|
|
| 2 |
Ki = 2.1 nM
|
|
|
|
CP0381531
|
5-[[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazine-1-carbothioyl]amino]-2-(3-hydroxy-6-oxoxanthen-9-yl)benzoic acid
Show/Hide
|
C35H30N6O7S
|
2
|
| 1 |
IC50 = 8.8 nM
|
|
|
| 2 |
Ki = 4.7 nM
|
|
|
|
CP0381529
|
3-[4-[[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]methyl]triazol-1-yl]-7-(diethylamino)chromen-2-one
Show/Hide
|
C30H35N9O4
|
2
|
| 1 |
IC50 = 52.4 nM
|
|
|
| 2 |
Ki = 29.9 nM
|
|
|
|
CP0462778
|
3-[2-(3,4-dihydro-1H-[1]benzofuro[3,2-c]pyridin-2-yl)ethyl]-2,8-dimethylpyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C23H23N3O2
|
1
|
| 1 |
IC50 = 112.2 nM
|
|
|
|
CP0506685
|
3-[2-(3,4-dihydro-1H-[1]benzofuro[3,2-c]pyridin-2-yl)ethyl]-9-methoxy-2-methylpyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C23H23N3O3
|
1
|
| 1 |
IC50 = 114.82 nM
|
|
|
|
CP0375044
|
2-benzyl-3-[2-(3,4-dihydro-1H-[1]benzofuro[3,2-c]pyridin-2-yl)ethyl]pyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C28H25N3O2
|
1
|
| 1 |
IC50 = 204.17 nM
|
|
|
|
CP0467592
|
3-[2-(3,4-dihydro-1H-[1]benzothiolo[3,2-c]pyridin-2-yl)ethyl]-2-methylpyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C22H21N3OS
|
1
|
| 1 |
IC50 = 213.8 nM
|
|
|
|
CP0375211
|
3-[2-(3,4-dihydro-1H-[1]benzofuro[3,2-c]pyridin-2-yl)ethyl]-2,6,8-trimethylpyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C24H25N3O2
|
1
|
| 1 |
IC50 = 239.88 nM
|
|
|
|
CP0479963
|
3-[2-(3,4-dihydro-1H-[1]benzofuro[3,2-c]pyridin-2-yl)ethyl]-9-hydroxy-2-methylpyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C22H21N3O3
|
1
|
| 1 |
IC50 = 245.47 nM
|
|
|
|
CP0503149
|
3-[2-(6-chloro-3,4-dihydro-1H-[1]benzofuro[3,2-c]pyridin-2-yl)ethyl]-2-methylpyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C22H20ClN3O2
|
1
|
| 1 |
IC50 = 281.84 nM
|
|
|
|
CP0398443
|
3-[2-(3,4-dihydro-1H-[1]benzofuro[3,2-c]pyridin-2-yl)ethyl]-2,7-dimethylpyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C23H23N3O2
|
1
|
| 1 |
IC50 = 288.4 nM
|
|
|
|
CP0437587
|
LUSAPERIDONE
Show/Hide
|
C22H21N3O2
|
1
|
| 1 |
IC50 = 346.74 nM
|
|
|
|
CP0430308
|
3-[2-(3,4-dihydro-1H-[1]benzofuro[3,2-c]pyridin-2-yl)ethyl]-2,6-dimethylpyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C23H23N3O2
|
1
|
| 1 |
IC50 = 398.11 nM
|
|
|
|
CP0509938
|
3-[2-(3,4-dihydro-1H-[1]benzofuro[3,2-c]pyridin-2-yl)ethyl]-7-iodo-2-methylpyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C22H20IN3O2
|
1
|
| 1 |
IC50 = 478.63 nM
|
|
|
|
CP0375207
|
3-[2-(3,4-dihydro-1H-[1]benzofuro[3,2-c]pyridin-2-yl)ethyl]-2,9-dimethylpyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C23H23N3O2
|
1
|
| 1 |
IC50 = 691.83 nM
|
|
|
|
CP0380435
|
7-chloro-3-[2-(3,4-dihydro-1H-[1]benzofuro[3,2-c]pyridin-2-yl)ethyl]-2-methylpyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C22H20ClN3O2
|
1
|
| 1 |
IC50 = 724.44 nM
|
|
|
|
CP0380633
|
3-[3-(3,4-dihydro-1H-[1]benzofuro[3,2-c]pyridin-2-yl)propyl]-2-methylpyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C23H23N3O2
|
1
|
| 1 |
IC50 = 812.83 nM
|
|
|
|
CP0480554
|
7-bromo-3-[2-(3,4-dihydro-1H-[1]benzofuro[3,2-c]pyridin-2-yl)ethyl]-2-methylpyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C22H20BrN3O2
|
1
|
| 1 |
IC50 = 891.25 nM
|
|
|
|
CP0409638
|
7,9-dichloro-3-[2-(3,4-dihydro-1H-[1]benzofuro[3,2-c]pyridin-2-yl)ethyl]-2-methylpyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C22H19Cl2N3O2
|
1
|
| 1 |
IC50 = 2570.4 nM
|
|
|
|
CP0037622
|
2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole
Show/Hide
|
C11H12N2O2
|
1
|
| 1 |
IC50 = 2884.03 nM
|
|
|
|
CP0030044
|
(+/-)-12-Methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-triaza-tribenzo[a,c,e]cycloheptene
Show/Hide
|
C17H19N3
|
1
|
| 1 |
IC50 = 3162.28 nM
|
|
|
|
CP0408409
|
3-[2-(3,4-dihydro-1H-[1]benzofuro[3,2-c]pyridin-2-yl)ethyl]-7,8-dimethoxy-2-methylpyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C24H25N3O4
|
1
|
| 1 |
IC50 = 5248.07 nM
|
|
|
|
CP0373529
|
9-chloro-3-[2-(3,4-dihydro-1H-[1]benzofuro[3,2-c]pyridin-2-yl)ethyl]-2-methyl-7-(trifluoromethyl)pyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C23H19ClF3N3O2
|
1
|
| 1 |
IC50 = 5888.44 nM
|
|
|
|
CP0377739
|
[(6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl] 5-(dithiolan-3-yl)pentanoate
Show/Hide
|
C27H33NO2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0061623
|
8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-azaspiro[4.5]decane-7,9-dione
Show/Hide
|
C22H31N3O3
|
4
|
| 1 |
Kd = 380.19 nM
|
|
|
| 2 |
Ki = 380.19 nM
|
|
|
| 3 |
Ki = 389.05 nM
|
|
|
| 4 |
Ki = 436.52 nM
|
|
|
|
CP0040814
|
[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(furan-2-yl)methanone
Show/Hide
|
C19H21N5O4
|
3
|
| 1 |
Ki = 0.04 nM
|
|
|
| 2 |
Ki = 0.58 nM
|
|
|
| 3 |
Ki = 0.5888 nM
|
|
|
|
CP0854007
|
[2-(2,6-Dimethoxy-phenoxy)-ethyl]-(4-phenyl-chroman-2-ylmethyl)-amine
Show/Hide
|
C26H29NO4
|
1
|
| 1 |
Ki = 0.05012 nM
|
|
|
|
CP0035002
|
(R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide
Show/Hide
|
C20H28N2O5S
|
1
|
| 1 |
Ki = 0.05012 nM
|
|
|
|
CP0430506
|
3-{1-[4-(5-Methylsulfanyl-1,1,3-trioxo-1,3-dihydro-1lambda*6*-benzo[d]isothiazol-2-yl)-butyl]-piperidin-4-yl}-3H-benzooxazol-2-one
Show/Hide
|
C24H27N3O5S2
|
1
|
| 1 |
Ki = 0.057 nM
|
|
|
|
CP0392625
|
3-{1-[4-(5-Methoxy-1,1,3-trioxo-1,3-dihydro-1lambda*6*-benzo[d]isothiazol-2-yl)-butyl]-piperidin-4-yl}-3H-benzooxazol-2-one
Show/Hide
|
C24H27N3O6S
|
1
|
| 1 |
Ki = 0.064 nM
|
|
|
|
CP0404641
|
4-(3,4-Difluoro-phenyl)-1-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid {3-[4-(2-cyano-4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide
Show/Hide
|
C27H28F3N5O2
|
1
|
| 1 |
Ki = 0.068 nM
|
|
|
|
CP0847938
|
4-(3,4-Difluoro-phenyl)-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid {3-[4-(2-cyano-4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide
Show/Hide
|
C26H26F3N5O2
|
1
|
| 1 |
Ki = 0.07 nM
|
|
|
|
CP0404455
|
3-{1-[4-(5-Chloro-1,1,3-trioxo-1,3-dihydro-1lambda*6*-benzo[d]isothiazol-2-yl)-butyl]-piperidin-4-yl}-3H-benzooxazol-2-one
Show/Hide
|
C23H24ClN3O5S
|
1
|
| 1 |
Ki = 0.077 nM
|
|
|
|
CP0395371
|
6-Fluoro-3-{1-[4-(1,1,3-trioxo-1,3-dihydro-1lambda*6*-benzo[d]isothiazol-2-yl)-butyl]-piperidin-4-yl}-3H-benzooxazol-2-one
Show/Hide
|
C23H24FN3O5S
|
1
|
| 1 |
Ki = 0.084 nM
|
|
|
|
CP0845244
|
[2-(2,6-Dimethoxy-phenoxy)-ethyl]-(4-phenyl-thiochroman-2-ylmethyl)-amine
Show/Hide
|
C26H29NO3S
|
1
|
| 1 |
Ki = 0.08913 nM
|
|
|
|
CP0505188
|
3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic acid (3-{4-[2-(3-nitrooxy-propoxy)-phenyl]-piperazin-1-yl}-propyl)-amide
Show/Hide
|
C33H36N4O7
|
1
|
| 1 |
Ki = 0.094 nM
|
|
|
|
CP0460865
|
3-{1-[4-(5-Methyl-1,1,3-trioxo-1,3-dihydro-1lambda*6*-benzo[d]isothiazol-2-yl)-butyl]-piperidin-4-yl}-3H-benzooxazol-2-one
Show/Hide
|
C24H27N3O5S
|
1
|
| 1 |
Ki = 0.099 nM
|
|
|
|
CP0430088
|
3-{1-[4-(1,1,3-Trioxo-1,3-dihydro-1lambda*6*-benzo[d]isothiazol-2-yl)-butyl]-piperidin-4-yl}-3H-benzooxazol-2-one
Show/Hide
|
C23H25N3O5S
|
1
|
| 1 |
Ki = 0.12 nM
|
|
|
|
CP0424535
|
(R)-4-(3,4-Difluoro-phenyl)-1-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid {3-[4-cyano-4-(4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide
Show/Hide
|
C27H28F3N5O2
|
1
|
| 1 |
Ki = 0.12 nM
|
|
|
|
CP0405241
|
4-(3,4-Difluoro-phenyl)-1,6-dimethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid {3-[4-(2-cyano-4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide
Show/Hide
|
C28H30F3N5O2
|
1
|
| 1 |
Ki = 0.12 nM
|
|
|
|
CP0460872
|
3-{1-[4-(5-Nitro-1,1,3-trioxo-1,3-dihydro-1lambda*6*-benzo[d]isothiazol-2-yl)-butyl]-piperidin-4-yl}-3H-benzooxazol-2-one
Show/Hide
|
C23H24N4O7S
|
1
|
| 1 |
Ki = 0.13 nM
|
|
|
|
CP0914602
|
4-(3,4-Difluoro-phenyl)-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid {3-[4-(2-cyano-phenyl)-piperidin-1-yl]-propyl}-amide
Show/Hide
|
C26H27F2N5O2
|
1
|
| 1 |
Ki = 0.13 nM
|
|
|
|
CP0850171
|
4-(3,4-Difluoro-phenyl)-3,6-dimethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid {3-[4-(4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide
Show/Hide
|
C27H31F3N4O2
|
1
|
| 1 |
Ki = 0.14 nM
|
|
|
|
CP0866800
|
4-(3,4-Difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid {3-[4-(2-cyano-4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide
Show/Hide
|
C28H30F3N5O3
|
1
|
| 1 |
Ki = 0.14 nM
|
|
|
|
CP0380264
|
3-{1-[4-(6-Nitro-1,1,3-trioxo-1,3-dihydro-1lambda*6*-benzo[d]isothiazol-2-yl)-butyl]-piperidin-4-yl}-3H-benzooxazol-2-one
Show/Hide
|
C23H24N4O7S
|
1
|
| 1 |
Ki = 0.16 nM
|
|
|
|
CP0862766
|
4-(3,4-Difluoro-phenyl)-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid {3-[4-cyano-4-(2-cyano-phenyl)-piperidin-1-yl]-propyl}-amide
Show/Hide
|
C27H26F2N6O2
|
1
|
| 1 |
Ki = 0.16 nM
|
|
|
|
CP0442589
|
3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic acid (3-{4-[2-(4-methyl-5-oxy-furazan-3-ylmethoxy)-phenyl]-piperazin-1-yl}-propyl)-amide
Show/Hide
|
C34H35N5O6
|
1
|
| 1 |
Ki = 0.16 nM
|
|
|
|
CP0082953
|
2,3-dihydro-1,4-benzodioxin-3-ylmethyl-[2-(2,6-dimethoxyphenoxy)ethyl]amine;hydrochloride
Show/Hide
|
C19H23NO5
|
3
|
| 1 |
Ki = 0.16 nM
|
|
|
| 2 |
Ki = 0.4266 nM
|
|
|
| 3 |
Ki = 0.97174 nM
|
|
|
|
CP0495472
|
N-[6-[(4-amino-6,7-dimethoxyquinazolin-2-yl)-methylamino]hexyl]-N-methylfuran-2-carboxamide
Show/Hide
|
C23H31N5O4
|
1
|
| 1 |
Ki = 0.166 nM
|
|
|
|
CP0847590
|
4-(3,4-Difluoro-phenyl)-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid {3-[4-cyano-4-(4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide
Show/Hide
|
C26H26F3N5O2
|
1
|
| 1 |
Ki = 0.17 nM
|
|
|
|
CP0920503
|
4-(3,4-Difluoro-phenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid {3-[4-(2-cyano-4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide
Show/Hide
|
C27H28F3N5O2
|
1
|
| 1 |
Ki = 0.17 nM
|
|
|
|
CP0920743
|
4-(3,4-Difluoro-phenyl)-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid {3-[4-(4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide
Show/Hide
|
C25H27F3N4O2
|
1
|
| 1 |
Ki = 0.17 nM
|
|
|
|
CP0379330
|
(R)-4-(3,4-Difluoro-phenyl)-1,3,6-trimethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid {3-[4-(4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide
Show/Hide
|
C28H33F3N4O2
|
1
|
| 1 |
Ki = 0.18 nM
|
|
|
|
CP0405271
|
(R)-4-(3,4-Difluoro-phenyl)-1,6-dimethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid {3-[4-(4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide
Show/Hide
|
C27H31F3N4O2
|
1
|
| 1 |
Ki = 0.18 nM
|
|
|
|
CP0402286
|
4-(3,4-Difluoro-phenyl)-1-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid {3-[4-cyano-4-(2-cyano-4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide
Show/Hide
|
C28H27F3N6O2
|
1
|
| 1 |
Ki = 0.18 nM
|
|
|
|
CP0463267
|
(S)-3-{(1R,3S)-3-[4-(2-Cyano-phenyl)-piperidin-1-yl]-cyclopentylcarbamoyl}-4-(3,4-difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
Show/Hide
|
C32H35F2N5O5
|
1
|
| 1 |
Ki = 0.24 nM
|
|
|
|
CP0868007
|
4-(3,4-Difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid {3-[4-(4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide
Show/Hide
|
C27H31F3N4O3
|
1
|
| 1 |
Ki = 0.24 nM
|
|
|
|
CP0848490
|
4-(3,4-Difluoro-phenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid {3-[4-(2-cyano-phenyl)-piperidin-1-yl]-propyl}-amide
Show/Hide
|
C27H29F2N5O2
|
1
|
| 1 |
Ki = 0.25 nM
|
|
|
|
CP0861076
|
2-{[2-(2,6-Dimethoxy-phenoxy)-ethylamino]-methyl}-4-phenyl-3,4-dihydro-2H-naphthalen-1-one
Show/Hide
|
C27H29NO4
|
1
|
| 1 |
Ki = 0.2512 nM
|
|
|
|
CP0163564
|
2-[2-[(3-chlorophenyl)methoxy]phenoxy]-N-[2-(2,6-dimethoxyphenoxy)ethyl]ethanamine
Show/Hide
|
C25H28ClNO5
|
1
|
| 1 |
Ki = 0.2512 nM
|
|
|
|
CP0184024
|
Clopenphendioxan
Show/Hide
|
C25H28ClNO5
|
1
|
| 1 |
Ki = 0.2512 nM
|
|
|
|
CP0042265
|
2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-isoindole-1,3-dione
Show/Hide
|
C23H27N3O3
|
1
|
| 1 |
Ki = 0.26 nM
|
|
|
|
CP0288408
|
1-[(4,4-diphenyl-1,3-dioxolan-2-yl)methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C27H30N2O3
|
1
|
| 1 |
Ki = 0.263 nM
|
|
|
|
CP0859288
|
1-((2,2-diphenyl-1,3-dioxolan-4-yl)methyl)-4-(2-methoxyphenyl)piperazine oxalate
Show/Hide
|
C29H32N2O7
|
1
|
| 1 |
Ki = 0.263 nM
|
|
|
|
CP0374601
|
2-{4-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-butyl}-isoindole-1,3-dione
Show/Hide
|
C24H26N4O3
|
1
|
| 1 |
Ki = 0.28 nM
|
|
|
|
CP0862789
|
1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-2-[1,2]dithiolan-3-yl-ethanone
Show/Hide
|
C19H25N5O3S2
|
1
|
| 1 |
Ki = 0.2884 nM
|
|
|
|
CP0453446
|
4-(3,4-Difluoro-phenyl)-1,3-dimethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid {3-[4-cyano-4-(2-cyano-4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide
Show/Hide
|
C29H29F3N6O2
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0105050
|
N-[2-(2,6-dimethoxyphenoxy)ethyl]-2-[2-[(3-nitrophenyl)methoxy]phenoxy]ethanamine
Show/Hide
|
C25H28N2O7
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
|
CP0879010
|
N-{6-[(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-methyl-amino]-hexyl}-3-dimethylaminomethyl-N-methyl-benzamide
Show/Hide
|
C28H40N6O3
|
1
|
| 1 |
Ki = 0.3236 nM
|
|
|
|
CP0437539
|
2-methoxy-5-[(2R)-2-[2-(2-propan-2-yloxyphenoxy)ethylamino]propyl]benzenesulfonamide
Show/Hide
|
C21H30N2O5S
|
1
|
| 1 |
Ki = 0.3388 nM
|
|
|
|
CP0345915
|
3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic acid {3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-amide
Show/Hide
|
C31H33N3O4
|
1
|
| 1 |
Ki = 0.34 nM
|
|
|
|
CP0376824
|
2-methoxy-5-[(2R)-2-[2-(2-phenylmethoxyphenoxy)ethylamino]propyl]benzenesulfonamide
Show/Hide
|
C25H30N2O5S
|
1
|
| 1 |
Ki = 0.3467 nM
|
|
|
|
CP0453018
|
(S)-3-[(1R,3R)-3-(4-Cyano-4-phenyl-piperidin-1-yl)-cyclopentylcarbamoyl]-4-(3,4-difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
Show/Hide
|
C32H35F2N5O5
|
1
|
| 1 |
Ki = 0.37 nM
|
|
|
|
CP0502334
|
(S)-4-(3,4-Difluoro-phenyl)-6-methoxymethyl-2-oxo-3-[(1R,3R)-3-(3',4',5',6'-tetrahydro-2'H-[2,4']bipyridinyl-1'-yl)-cyclopentylcarbamoyl]-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
Show/Hide
|
C30H35F2N5O5
|
1
|
| 1 |
Ki = 0.38 nM
|
|
|
|
CP0132465
|
1-[2-(1,3-benzodioxol-5-yl)ethyl]-4-(2-propan-2-yloxyphenyl)piperazine
Show/Hide
|
C22H28N2O3
|
1
|
| 1 |
Ki = 0.389 nM
|
|
|
|
CP0859718
|
4-(3,4-Difluoro-phenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid {3-[4-(4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide
Show/Hide
|
C26H29F3N4O2
|
1
|
| 1 |
Ki = 0.39 nM
|
|
|
|
CP0424534
|
4-(3,4-Difluoro-phenyl)-1,6-dimethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid {3-[4-cyano-4-(4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide
Show/Hide
|
C28H30F3N5O2
|
1
|
| 1 |
Ki = 0.39 nM
|
|
|
|
CP0892862
|
[2-(2-Benzyl-phenoxy)-ethyl]-[2-(2,6-dimethoxy-phenoxy)-ethyl]-amine
Show/Hide
|
C25H29NO4
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
|
CP0370354
|
N-[2-(2,6-dimethoxyphenoxy)ethyl]-2-[2-[(3-methylphenyl)methoxy]phenoxy]ethanamine
Show/Hide
|
C26H31NO5
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
|
CP0429286
|
(S)-4-(3,4-Difluoro-phenyl)-6-methoxymethyl-2-oxo-3-[(1R,3S)-3-(3',4',5',6'-tetrahydro-2'H-[2,4']bipyridinyl-1'-yl)-cyclopentylcarbamoyl]-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
Show/Hide
|
C30H35F2N5O5
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0394914
|
2-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)-2H-pyrrolo[3,4-c]pyridine-1,3-dione
Show/Hide
|
C26H32N4O3
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0847195
|
(S)-N-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-2-(2,6-dimethoxyphenoxy)ethanamine hydrochloride
Show/Hide
|
C19H24ClNO5
|
1
|
| 1 |
Ki = 0.4074 nM
|
|
|
|
CP0433386
|
N-[[(3S)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-2-(2,6-dimethoxyphenoxy)ethanamine
Show/Hide
|
C19H23NO5
|
1
|
| 1 |
Ki = 0.4074 nM
|
|
|
|
CP0846086
|
(S)-N-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-2-(2,6-dimethoxyphenoxy)ethanamine oxalate
Show/Hide
|
C21H25NO9
|
1
|
| 1 |
Ki = 0.4074 nM
|
|
|
|
CP0422260
|
N-[2-[2-[(4-amino-6,7-dimethoxyquinazolin-2-yl)-methylamino]ethyldisulfanyl]ethyl]-N-methylfuran-2-carboxamide
Show/Hide
|
C21H27N5O4S2
|
1
|
| 1 |
Ki = 0.4169 nM
|
|
|
|
CP0892079
|
4-(3,4-Difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid {3-[4-(2-cyano-phenyl)-piperidin-1-yl]-propyl}-amide
Show/Hide
|
C28H31F2N5O3
|
1
|
| 1 |
Ki = 0.42 nM
|
|
|
|
CP0455350
|
(S)-3-{(1S,3R)-3-[4-(2-Cyano-phenyl)-piperazin-1-yl]-cyclopentylcarbamoyl}-4-(3,4-difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
Show/Hide
|
C31H34F2N6O5
|
1
|
| 1 |
Ki = 0.44 nM
|
|
|
|
CP0863088
|
4-(3,4-Difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid [3-(3',4',5',6'-tetrahydro-2'H-[2,4']bipyridinyl-1'-yl)-propyl]-amide
Show/Hide
|
C26H31F2N5O3
|
1
|
| 1 |
Ki = 0.45 nM
|
|
|
|
CP0455391
|
(S)-3-{(1R,3R)-3-[4-(2-Cyano-phenyl)-piperidin-1-yl]-cyclopentylcarbamoyl}-4-(3,4-difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
Show/Hide
|
C32H35F2N5O5
|
1
|
| 1 |
Ki = 0.46 nM
|
|
|
|
CP0316443
|
N-[2-(2,6-dimethoxyphenoxy)ethyl]-2-(2-phenylmethoxyphenoxy)ethanamine
Show/Hide
|
C25H29NO5
|
2
|
| 1 |
Ki = 0.4677 nM
|
|
|
| 2 |
Ki = 0.969882 nM
|
|
|
|
CP0108664
|
N-[[(3S)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-2-[(6-methoxy-1-benzofuran-7-yl)oxy]ethanamine;hydrochloride
Show/Hide
|
C20H22ClNO5
|
1
|
| 1 |
Ki = 0.4898 nM
|
|
|
|
CP0410683
|
benzyl (4aS,8aR)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxaline-1-carboxylate
Show/Hide
|
C26H31N5O4
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
|
CP0894510
|
[2-(2,6-Dimethoxy-phenoxy)-ethyl]-(4-phenyl-1,2,3,4-tetrahydro-naphthalen-2-ylmethyl)-amine
Show/Hide
|
C27H31NO3
|
1
|
| 1 |
Ki = 0.5129 nM
|
|
|
|
CP0048996
|
CAS_74191-85-8
Show/Hide
|
C23H25N5O5
|
2
|
| 1 |
Ki = 0.537 nM
|
|
|
| 2 |
Ki = 0.7762 nM
|
|
|
|
CP0210810
|
[(4aS,8aR)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-(furan-2-yl)methanone
Show/Hide
|
C23H27N5O4
|
1
|
| 1 |
Ki = 0.5888 nM
|
|
|
|
CP0502347
|
(S)-3-{(1S,3R)-3-[4-(2-Cyano-phenyl)-piperidin-1-yl]-cyclopentylcarbamoyl}-4-(3,4-difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
Show/Hide
|
C32H35F2N5O5
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0441539
|
4-(3,4-Difluoro-phenyl)-1,6-dimethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid {3-[4-cyano-4-(2-cyano-4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide
Show/Hide
|
C29H29F3N6O2
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0472991
|
2-methoxy-5-[(2R)-2-[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethylamino]propyl]benzenesulfonamide
Show/Hide
|
C20H25F3N2O5S
|
1
|
| 1 |
Ki = 0.6026 nM
|
|
|
|
CP0415319
|
1-[[(2S,4S)-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-2-phenyl-1,3-dioxolan-2-yl]methyl]azepan-2-one
Show/Hide
|
C28H37N3O4
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0386945
|
N-[(3S)-1-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperidin-3-yl]furan-2-carboxamide
Show/Hide
|
C20H23N5O4
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0905131
|
1-[(5,5-Diphenyloxolan-2-yl)methyl]-4-(2-methoxyphenyl)-piperazine Oxalate Salt
Show/Hide
|
C30H34N2O6
|
1
|
| 1 |
Ki = 0.6457 nM
|
|
|
|
CP0910843
|
(S)-2-(2,6-dimethoxyphenoxy)-N-((8-fluoro-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)ethanamine hydrochloride
Show/Hide
|
C19H23ClFNO5
|
1
|
| 1 |
Ki = 0.6457 nM
|
|
|
|
CP0239195
|
6-(3,5-dimethyl-4-isoxazolylsulfonamido)-1'-[2-(1-naphthyl)ethyl]-4-oxospiro[3,4-dihydro-2H-chromene-2,4'-(hexahydropyridine)]
Show/Hide
|
C30H31N3O5S
|
1
|
| 1 |
Ki = 0.69 nM
|
|
|
|
CP0494781
|
3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic acid (3-{4-[2-(4-cyano-5-oxy-furazan-3-ylmethoxy)-phenyl]-piperazin-1-yl}-propyl)-amide
Show/Hide
|
C34H32N6O6
|
1
|
| 1 |
Ki = 0.73 nM
|
|
|
|
CP0409033
|
6-(3,4-Difluoro-phenyl)-5-{3-[4-(4-fluoro-phenyl)-piperidin-1-yl]-propylcarbamoyl}-3,4-dimethyl-2-oxo-3,6-dihydro-2H-pyrimidine-1-carboxylic acid methyl ester
Show/Hide
|
C29H33F3N4O4
|
1
|
| 1 |
Ki = 0.75 nM
|
|
|
|
CP0405465
|
6-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)-6H-pyrrolo[3,4-b]pyridine-5,7-dione
Show/Hide
|
C26H32N4O3
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0307921
|
N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C24H26FN3O3S2
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0847183
|
[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-[1,2]dithiolan-3-yl-methanone
Show/Hide
|
C18H23N5O3S2
|
1
|
| 1 |
Ki = 0.8128 nM
|
|
|
|
CP0475824
|
2-(2,6-dimethoxyphenoxy)-N-[(2-phenyl-2H-chromen-3-yl)methyl]ethanamine
Show/Hide
|
C26H27NO4
|
1
|
| 1 |
Ki = 0.853698 nM
|
|
|
|
CP0372320
|
3-[[2-(2,6-dimethoxyphenoxy)ethylamino]methyl]-2-phenyl-2,3-dihydrothiochromen-4-one
Show/Hide
|
C26H27NO4S
|
1
|
| 1 |
Ki = 0.870404 nM
|
|
|
|
CP0406086
|
1-[[(2S,4S)-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-2-phenyl-1,3-dioxolan-2-yl]methyl]piperidin-2-one
Show/Hide
|
C27H35N3O4
|
1
|
| 1 |
Ki = 0.871 nM
|
|
|
|
CP0519946
|
1-[(4aR,8aS)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-2-(2-methoxy-6-propan-2-ylphenoxy)ethanone
Show/Hide
|
C30H39N5O5
|
1
|
| 1 |
Ki = 0.871 nM
|
|
|
|
CP0912440
|
(S)-2-[((2-(2,6-Dimethoxyphenoxy)ethyl)amino)methyl]-8-chloro-1,4-benzodioxane hydrochloride
Show/Hide
|
C19H23Cl2NO5
|
1
|
| 1 |
Ki = 0.8913 nM
|
|
|
|
CP0402532
|
(S)-3-{(1R,3R)-3-[4-(2-Cyano-phenyl)-piperazin-1-yl]-cyclopentylcarbamoyl}-4-(3,4-difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
Show/Hide
|
C31H34F2N6O5
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0404407
|
2-[[2-(2,6-dimethoxyphenoxy)ethylamino]methyl]-3-phenyl-3,4-dihydro-2H-naphthalen-1-one
Show/Hide
|
C27H29NO4
|
1
|
| 1 |
Ki = 0.906335 nM
|
|
|
|
CP0868640
|
4-(3,4-Difluoro-phenyl)-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid {3-[4-(4-fluoro-phenyl)-4-hydroxy-piperidin-1-yl]-propyl}-amide
Show/Hide
|
C25H27F3N4O3
|
1
|
| 1 |
Ki = 0.91 nM
|
|
|
|
CP0943167
|
(S)-2-(2,6-dimethoxyphenoxy)-N-((8-methoxy-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)ethanamine hydrochloride
Show/Hide
|
C20H26ClNO6
|
1
|
| 1 |
Ki = 0.912 nM
|
|
|
|
CP0404393
|
2-(2,6-dimethoxyphenoxy)-N-[(3-phenyl-3,4-dihydro-2H-chromen-2-yl)methyl]ethanamine
Show/Hide
|
C26H29NO4
|
1
|
| 1 |
Ki = 0.928908 nM
|
|
|
|
CP0441147
|
3-[[2-(2,6-dimethoxyphenoxy)ethylamino]methyl]-2-phenyl-2,3-dihydrochromen-4-one
Show/Hide
|
C26H27NO5
|
1
|
| 1 |
Ki = 0.964731 nM
|
|
|
|
CP0463641
|
methyl (4S)-3-[[(1R,3S)-3-(4-cyano-4-phenylpiperidin-1-yl)cyclopentyl]carbamoyl]-4-(3,4-difluorophenyl)-6-(methoxymethyl)-2-oxo-1,4-dihydropyrimidine-5-carboxylate
Show/Hide
|
C32H35F2N5O5
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0447962
|
8-Chloro-2-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethylamino}-6-methyl-6H-1,6,7,9a-tetraaza-fluoren-5-one
Show/Hide
|
C23H26ClN7O2
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0386458
|
N-[2-(2-methoxy-6-nitrophenoxy)ethyl]-2-(2-phenylmethoxyphenoxy)ethanamine
Show/Hide
|
C24H26N2O6
|
1
|
| 1 |
Ki = 1.122 nM
|
|
|
|
CP0132460
|
1-(2-ethoxyphenyl)-4-[2-(4-methoxyphenyl)ethyl]piperazine
Show/Hide
|
C21H28N2O2
|
1
|
| 1 |
Ki = 1.122 nM
|
|
|
|
CP0307245
|
1-[2-(1,3-benzodioxol-5-yl)ethyl]-4-(2-ethoxyphenyl)piperazine
Show/Hide
|
C21H26N2O3
|
1
|
| 1 |
Ki = 1.122 nM
|
|
|
|
CP0436897
|
5-Methyl-3-{1-[4-(1,1,3-trioxo-1,3-dihydro-1lambda*6*-benzo[d]isothiazol-2-yl)-butyl]-piperidin-4-yl}-3H-benzooxazol-2-one
Show/Hide
|
C24H27N3O5S
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0881025
|
(S)-2-[((2-(2-methoxy-6-phenylphenoxy)ethyl)amino)methyl]-1,4-benzodioxane hydrochloride
Show/Hide
|
C24H26ClNO4
|
1
|
| 1 |
Ki = 1.202 nM
|
|
|
|
CP0247776
|
2-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-[1,4]naphthoquinone
Show/Hide
|
C24H23N5O4
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0180112
|
N-[2-(2,6-dimethoxyphenoxy)ethyl]-2-[2-[(4-nitrophenyl)methoxy]phenoxy]ethanamine
Show/Hide
|
C25H28N2O7
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0415316
|
1-[[(2R,4S)-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-2-phenyl-1,3-dioxolan-2-yl]methyl]pyrrolidin-2-one
Show/Hide
|
C26H33N3O4
|
1
|
| 1 |
Ki = 1.38 nM
|
|
|
|
CP0855768
|
1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-5-[1,2]dithiolan-3-yl-pentan-1-one
Show/Hide
|
C22H31N5O3S2
|
1
|
| 1 |
Ki = 1.413 nM
|
|
|
|
CP0184026
|
2-[2-[(2-chlorophenyl)methoxy]phenoxy]-N-[2-(2,6-dimethoxyphenoxy)ethyl]ethanamine
Show/Hide
|
C25H28ClNO5
|
1
|
| 1 |
Ki = 1.413 nM
|
|
|
|
CP0861255
|
(S)-N-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-2-(2-methoxynaphthalen-1-yloxy)ethanamine hydrochloride
Show/Hide
|
C22H24ClNO4
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0254827
|
N-[2-(2,6-dimethoxyphenoxy)ethyl]-2-[2-[(2-methylphenyl)methoxy]phenoxy]ethanamine
Show/Hide
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C26H31NO5
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1
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| 1 |
Ki = 1.585 nM
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CP0432824
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(S)-3-{(1R,3S)-3-[4-(2-Cyano-phenyl)-piperazin-1-yl]-cyclopentylcarbamoyl}-4-(3,4-difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
Show/Hide
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C31H34F2N6O5
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1
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| 1 |
Ki = 1.6 nM
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CP0453508
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4-[2-(4-{3-[(3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carbonyl)-amino]-propyl}-piperazin-1-yl)-phenoxymethyl]-2-oxy-furazan-3-carboxylic acid amide
Show/Hide
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C34H34N6O7
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1
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| 1 |
Ki = 1.8 nM
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CP0394919
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2-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)-2H-benzo[e]isoindole-1,3-dione
Show/Hide
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C31H35N3O3
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1
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| 1 |
Ki = 1.8 nM
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CP0421980
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N-[6-[(4-amino-6,7-dimethoxyquinazolin-2-yl)-methylamino]hexyl]-N-methyl-2,3-dihydro-1,4-benzodioxine-3-carboxamide
Show/Hide
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C27H35N5O5
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1
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| 1 |
Ki = 1.862 nM
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CP0475365
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[(4aS,8aR)-4-[4-(dipropylamino)-6,7-dimethoxyquinazolin-2-yl]-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-(furan-2-yl)methanone
Show/Hide
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C29H39N5O4
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1
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| 1 |
Ki = 1.862 nM
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CP0519411
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8-Chloro-6-methyl-2-[2-(4-phenyl-piperazin-1-yl)-ethylamino]-6H-1,6,7,9a-tetraaza-fluoren-5-one
Show/Hide
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C22H24ClN7O
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1
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| 1 |
Ki = 1.93 nM
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CP0105052
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N-[2-(2,6-dimethoxyphenoxy)ethyl]-2-[2-[(4-methylphenyl)methoxy]phenoxy]ethanamine
Show/Hide
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C26H31NO5
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1
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| 1 |
Ki = 1.995 nM
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CP0126496
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N-[2-(2,6-dimethoxyphenoxy)ethyl]-2-[2-[(3-methoxyphenyl)methoxy]phenoxy]ethanamine
Show/Hide
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C26H31NO6
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1
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| 1 |
Ki = 1.995 nM
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CP0254826
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N-[2-(2,6-dimethoxyphenoxy)ethyl]-2-[2-[(2-methoxyphenyl)methoxy]phenoxy]ethanamine
Show/Hide
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C26H31NO6
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1
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| 1 |
Ki = 1.995 nM
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CP0316444
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N-[2-(2,6-dimethoxyphenoxy)ethyl]-2-[2-[(4-methoxyphenyl)methoxy]phenoxy]ethanamine
Show/Hide
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C26H31NO6
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1
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| 1 |
Ki = 1.995 nM
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CP0375895
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2-(2-ethoxyphenoxy)-N-[2-(2-phenylmethoxyphenoxy)ethyl]ethanamine
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C25H29NO4
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1
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| 1 |
Ki = 1.995 nM
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CP0087722
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N-[[(3S)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-2-[(6-methoxy-2,3-dihydro-1-benzofuran-7-yl)oxy]ethanamine;hydrochloride
Show/Hide
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C20H24ClNO5
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1
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| 1 |
Ki = 1.995 nM
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CP0068101
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1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(2-propan-2-yloxyphenyl)piperazine
Show/Hide
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C23H32N2O3
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1
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| 1 |
Ki = 1.995 nM
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CP0421705
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8-[[(2S,4S)-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-2-phenyl-1,3-dioxolan-2-yl]methyl]-8-azaspiro[4.5]decane-7,9-dione
Show/Hide
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C31H39N3O5
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1
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| 1 |
Ki = 2.042 nM
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CP0382789
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N-[(2,2-diphenyl-1,3-dioxolan-4-yl)methyl]-2-(2-propan-2-yloxyphenoxy)ethanamine
Show/Hide
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C27H31NO4
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1
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| 1 |
Ki = 2.089 nM
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CP0132464
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1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(2-ethoxyphenyl)piperazine
Show/Hide
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C22H30N2O3
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1
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| 1 |
Ki = 2.089 nM
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CP0917590
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(S)-2-[((2-(2,6-Dimethoxyphenoxy)ethyl)amino)methyl]-8-hydroxy-1,4-benzodioxane hydrochloride
Show/Hide
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C19H24ClNO6
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1
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| 1 |
Ki = 2.188 nM
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CP0410841
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3-Acetyl-4-(3,4-difluoro-phenyl)-1,6-dimethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid {3-[4-(4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide
Show/Hide
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C29H33F3N4O3
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1
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| 1 |
Ki = 2.2 nM
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CP0454587
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1-[2-(4-methoxyphenyl)ethyl]-4-(2-propan-2-yloxyphenyl)piperazine
Show/Hide
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C22H30N2O2
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1
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| 1 |
Ki = 2.239 nM
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CP0406359
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(S)-3-[(1S,3S)-3-(4-Cyano-4-phenyl-piperidin-1-yl)-cyclopentylcarbamoyl]-4-(3,4-difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
Show/Hide
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C32H35F2N5O5
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1
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| 1 |
Ki = 2.3 nM
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CP0455129
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(S)-4-(3,4-Difluoro-phenyl)-1-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid {3-[4-cyano-4-(4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide
Show/Hide
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C27H28F3N5O2
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1
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| 1 |
Ki = 2.3 nM
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CP0869545
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[2-(2,6-Dimethoxy-phenoxy)-ethyl]-(4-phenyl-thiochroman-2-ylmethyl)-amine
Show/Hide
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C26H29NO3S
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1
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| 1 |
Ki = 2.344 nM
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CP0448487
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(S)-3-[(1S,3R)-3-(4-Cyano-4-phenyl-piperidin-1-yl)-cyclopentylcarbamoyl]-4-(3,4-difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
Show/Hide
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C32H35F2N5O5
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1
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| 1 |
Ki = 2.4 nM
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CP0528362
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(S)-3-{(1S,3S)-3-[4-(2-Cyano-phenyl)-piperidin-1-yl]-cyclopentylcarbamoyl}-4-(3,4-difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
Show/Hide
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C32H35F2N5O5
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1
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| 1 |
Ki = 2.4 nM
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CP0862519
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4-(3,4-Difluoro-phenyl)-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid [3-(3',4',5',6'-tetrahydro-2'H-[2,4']bipyridinyl-1'-yl)-propyl]-amide
Show/Hide
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C24H27F2N5O2
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1
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| 1 |
Ki = 2.5 nM
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CP0411964
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N-[2-(2-chloro-6-methoxyphenoxy)ethyl]-2-(2-phenylmethoxyphenoxy)ethanamine
Show/Hide
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C24H26ClNO4
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1
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| 1 |
Ki = 2.512 nM
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CP0416570
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N-[2-(2-methoxy-6-methylphenoxy)ethyl]-2-(2-phenylmethoxyphenoxy)ethanamine
Show/Hide
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C25H29NO4
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1
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| 1 |
Ki = 2.512 nM
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CP0919262
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4-(3,4-Difluoro-phenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid [3-(3',4',5',6'-tetrahydro-2'H-[2,4']bipyridinyl-1'-yl)-propyl]-amide
Show/Hide
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C25H29F2N5O2
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1
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| 1 |
Ki = 2.6 nM
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CP0421822
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1-[(6,6-diphenyl-1,4-dioxan-2-yl)methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
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C28H32N2O3
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1
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| 1 |
Ki = 2.63 nM
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CP0444701
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5,6-dichloro-2-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)isoindoline-1,3-dione
Show/Hide
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C27H31Cl2N3O3
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1
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| 1 |
Ki = 2.7 nM
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CP0154868
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1-[2-(3-methoxyphenyl)ethyl]-4-(2-propan-2-yloxyphenyl)piperazine
Show/Hide
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C22H30N2O2
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1
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| 1 |
Ki = 2.754 nM
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CP0933240
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(S)-2-[((2-(2-methoxy-5,6,7,8-tetrahydronaphthoxy)ethyl)amino)methyl]-1,4-benzodioxane hydrochloride
Show/Hide
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C22H28ClNO4
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1
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| 1 |
Ki = 2.818 nM
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CP0327530
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[(4aR,8aS)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-(2,3-dihydro-1,4-benzodioxin-3-yl)methanone
Show/Hide
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C27H31N5O5
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1
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| 1 |
Ki = 2.818 nM
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CP0374560
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1-[[(2S,4S)-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-2-phenyl-1,3-dioxolan-2-yl]methyl]pyrrolidine-2,5-dione
Show/Hide
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C26H31N3O5
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1
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| 1 |
Ki = 2.884 nM
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CP0240495
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1-(2-ethoxyphenyl)-4-[2-(3-methoxyphenyl)ethyl]piperazine
Show/Hide
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C21H28N2O2
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1
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| 1 |
Ki = 2.951 nM
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CP0455988
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3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-8-(3-nitrophenyl)sulfonyl-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
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C25H32N4O7S
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1
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| 1 |
Ki = 3.02 nM
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CP0436773
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6-Methyl-3-{1-[4-(1,1,3-trioxo-1,3-dihydro-1lambda*6*-benzo[d]isothiazol-2-yl)-butyl]-piperidin-4-yl}-3H-benzooxazol-2-one
Show/Hide
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C24H27N3O5S
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1
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| 1 |
Ki = 3.1 nM
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CP0375896
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N-[2-(2,6-dimethoxyphenyl)sulfanylethyl]-2-(2-phenylmethoxyphenoxy)ethanamine
Show/Hide
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C25H29NO4S
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1
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| 1 |
Ki = 3.162 nM
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CP0411965
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2-(2-methoxyphenoxy)-N-[2-(2-phenylmethoxyphenoxy)ethyl]ethanamine
Show/Hide
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C24H27NO4
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1
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| 1 |
Ki = 3.162 nM
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CP0416569
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N-[2-(2,6-diethoxyphenoxy)ethyl]-2-(2-phenylmethoxyphenoxy)ethanamine
Show/Hide
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C27H33NO5
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1
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| 1 |
Ki = 3.162 nM
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CP0421978
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[(4aS,8aR)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-(2,3-dihydro-1,4-benzodioxin-3-yl)methanone
Show/Hide
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C27H31N5O5
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1
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| 1 |
Ki = 3.388 nM
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CP0872936
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(+)-2-[(4aS,8aR)-4-(5-bromo-2-furoyl)octahydroquinoxalin-1(2H)-yl]-6,7-dimethoxyquinazolin-4-amine
Show/Hide
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C23H26BrN5O4
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1
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| 1 |
Ki = 3.467 nM
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CP0068100
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1-[2-(1,3-benzodioxol-5-yl)ethyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
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C20H24N2O3
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1
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| 1 |
Ki = 3.467 nM
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CP0243183
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N-[[(3S)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-2-[(6-methoxy-2,3-dihydro-1H-indol-7-yl)oxy]ethanamine;dihydrochloride
Show/Hide
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C20H26Cl2N2O4
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1
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| 1 |
Ki = 3.802 nM
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CP0872837
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(+)-2-[(4aS,8aR)-4-benzoyloctahydroquinoxalin-1(2H)-yl]-6,7-dimethoxyquinazolin-4-amine
Show/Hide
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C25H29N5O3
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1
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| 1 |
Ki = 4.169 nM
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CP0049024
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1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)piperazine
Show/Hide
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C19H25N5O4
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1
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| 1 |
Ki = 4.2 nM
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CP0880972
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4-(3,4-Difluoro-phenyl)-2-oxo-6-trifluoromethyl-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid {3-[4-(2-cyano-4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide
Show/Hide
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C27H25F6N5O2
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1
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| 1 |
Ki = 4.2 nM
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CP0882784
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(+)-6,7-dimethoxy-2-[(4aS,8aR)-4-(2-thienylcarbonyl)octahydroquinoxalin-1(2H)-yl]quinazolin-4-amine
Show/Hide
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C23H27N5O3S
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1
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| 1 |
Ki = 4.266 nM
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CP0846825
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(R)-N-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-2-(2-methoxynaphthalen-1-yloxy)ethanaminium chloride
Show/Hide
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C22H24ClNO4
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1
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| 1 |
Ki = 4.571 nM
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CP0688480
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2-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-8-(4-methylbenzenesulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
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C26H35N3O5S
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1
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| 1 |
Ki = 4.571 nM
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CP0465015
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(S)-4-(3,4-Difluoro-phenyl)-6-methoxymethyl-2-oxo-3-[(1S,3R)-3-(3',4',5',6'-tetrahydro-2'H-[2,4']bipyridinyl-1'-yl)-cyclopentylcarbamoyl]-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
Show/Hide
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C30H35F2N5O5
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1
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| 1 |
Ki = 4.7 nM
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CP0437121
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5-Acetyl-4-amino-2-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-6-phenyl-2H-pyridazin-3-one
Show/Hide
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C25H29N5O3
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1
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| 1 |
Ki = 4.75 nM
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CP0445362
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(S)-3-{(1S,3S)-3-[4-(2-Cyano-phenyl)-piperazin-1-yl]-cyclopentylcarbamoyl}-4-(3,4-difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
Show/Hide
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C31H34F2N6O5
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1
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| 1 |
Ki = 4.8 nM
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CP0439525
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2-[2-[2-(2-phenylmethoxyphenoxy)ethylamino]ethoxy]benzene-1,3-diol
Show/Hide
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C23H25NO5
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1
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| 1 |
Ki = 5.012 nM
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CP0067759
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1-(2-phenylethyl)-4-(2-propan-2-yloxyphenyl)piperazine
Show/Hide
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C21H28N2O
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1
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| 1 |
Ki = 5.012 nM
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CP0272023
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3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-8-(4-nitrophenyl)sulfonyl-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
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C25H32N4O7S
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1
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| 1 |
Ki = 5.248 nM
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CP0097484
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CYCLAZOSIN
Show/Hide
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C23H27N5O4
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2
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| 1 |
Ki = 5.495 nM
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| 2 |
Ki = 12.3 nM
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CP0483083
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benzyl (4aR,8aS)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxaline-1-carboxylate
Show/Hide
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C26H31N5O4
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1
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| 1 |
Ki = 5.495 nM
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CP0889460
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(S)-2-[((2-(2-methoxy-5-phenylphenoxy)ethyl)amino)methyl]-1,4-benzodioxane hydrochloride
Show/Hide
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C24H26ClNO4
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1
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| 1 |
Ki = 5.623 nM
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CP0860648
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(R)-2-[((2-(2,6-Dimethoxyphenoxy)ethyl)amino)methyl]-8-chloro-1,4-benzodioxane hydrochloride
Show/Hide
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C19H23Cl2NO5
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1
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| 1 |
Ki = 5.623 nM
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CP0390476
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1-[(4aR,8aS)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]hexan-1-one
Show/Hide
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C24H35N5O3
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1
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| 1 |
Ki = 5.754 nM
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CP0403966
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8-Chloro-2-{2-[4-(2-chloro-phenyl)-piperazin-1-yl]-ethylamino}-6-methyl-6H-1,6,7,9a-tetraaza-fluoren-5-one
Show/Hide
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C22H23Cl2N7O
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1
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| 1 |
Ki = 5.93 nM
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CP0416571
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N-[2-(2,6-dichlorophenoxy)ethyl]-2-(2-phenylmethoxyphenoxy)ethanamine
Show/Hide
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C23H23Cl2NO3
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1
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| 1 |
Ki = 6.31 nM
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CP0657011
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2-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-8-phenyl-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
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C25H33N3O3
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1
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| 1 |
Ki = 6.457 nM
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CP0697681
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8-(4-Chlorobenzenesulfonyl)-2-{[4-(2-methoxyphenyl)piperazin-1-yl]methyl}-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
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C25H32ClN3O5S
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1
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| 1 |
Ki = 6.457 nM
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CP0448610
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N-[1'-[2-(2-methoxyphenyl)ethyl]-4-oxospiro[3H-chromene-2,4'-piperidine]-7-yl]methanesulfonamide
Show/Hide
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C23H28N2O5S
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1
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| 1 |
Ki = 6.5 nM
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CP0373754
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N-[(2,2-diphenyl-1,3-dioxolan-4-yl)methyl]-2-(2-ethoxyphenoxy)ethanamine
Show/Hide
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C26H29NO4
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1
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| 1 |
Ki = 6.607 nM
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CP0416404
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1-[[(2S,4S)-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-2-phenyl-1,3-dioxolan-2-yl]methyl]piperidine-2,6-dione
Show/Hide
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C27H33N3O5
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1
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| 1 |
Ki = 6.607 nM
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CP0446806
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1-[(4aR,8aS)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-2,2-dimethylpropan-1-one
Show/Hide
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C23H33N5O3
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1
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| 1 |
Ki = 6.607 nM
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CP0116923
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8-benzyl-3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
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C26H35N3O3
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1
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| 1 |
Ki = 6.761 nM
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CP0412412
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2-[[(3S)-1-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperidin-3-yl]amino]naphthalene-1,4-dione
Show/Hide
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C25H25N5O4
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1
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| 1 |
Ki = 7.079 nM
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CP0234085
|
2-(2,2-diphenyl-1,3-dioxolan-4-yl)-N-[2-(2-methoxyphenoxy)ethyl]ethanamine;oxalic acid
Show/Hide
|
C28H31NO8
|
1
|
| 1 |
Ki = 7.244 nM
|
|
|
|
CP0289979
|
N-[2-(2,6-dimethoxyphenoxy)ethyl]-2-[2-[(2-nitrophenyl)methoxy]phenoxy]ethanamine
Show/Hide
|
C25H28N2O7
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
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CP0373940
|
N-[2-(2,6-dimethylphenoxy)ethyl]-2-(2-phenylmethoxyphenoxy)ethanamine
Show/Hide
|
C25H29NO3
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
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CP0250925
|
3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-8-thiophen-2-ylsulfonyl-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
|
C23H31N3O5S2
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
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CP0433574
|
8-(benzenesulfonyl)-3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
|
C25H33N3O5S
|
1
|
| 1 |
Ki = 7.943 nM
|
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|
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CP0395275
|
6-(1-methyl-1H-4-imidazolylsulfonamido)-1'-[2-(1-naphthyl)ethyl]-4-oxospiro[3,4-dihydro-2H-chromene-2,4'-(hexahydropyridine)]
Show/Hide
|
C29H30N4O4S
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0448993
|
N-[1'-[2-(2-methyl-1H-indol-3-yl)ethyl]-4-oxospiro[3H-chromene-2,4'-piperidine]-7-yl]methanesulfonamide
Show/Hide
|
C25H29N3O4S
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0463780
|
(S)-4-(3,4-Difluoro-phenyl)-6-methoxymethyl-2-oxo-3-[(1S,3S)-3-(3',4',5',6'-tetrahydro-2'H-[2,4']bipyridinyl-1'-yl)-cyclopentylcarbamoyl]-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
Show/Hide
|
C30H35F2N5O5
|
1
|
| 1 |
Ki = 8.3 nM
|
|
|
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CP0250926
|
1-(1,4-dioxa-8-thiaspiro[4.5]decan-3-ylmethyl)-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C19H28N2O3S
|
1
|
| 1 |
Ki = 8.511 nM
|
|
|
|
CP0772147
|
2-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-8-[4(trifluoromethoxy)benzenesulfonyl]-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
|
C26H32F3N3O6S
|
1
|
| 1 |
Ki = 8.913 nM
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|
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CP0406705
|
N-[[(3R)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-2-[(6-methoxy-1-benzofuran-7-yl)oxy]ethanamine;hydrochloride
Show/Hide
|
C20H22ClNO5
|
1
|
| 1 |
Ki = 9.12 nM
|
|
|
|
CP0519947
|
1-[(4aS,8aR)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]ethanone
Show/Hide
|
C20H27N5O3
|
1
|
| 1 |
Ki = 9.12 nM
|
|
|
|
CP0405158
|
N-[[(3R)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-2-(2-methoxy-6-phenylphenoxy)ethanamine;hydrochloride
Show/Hide
|
C24H25NO4
|
1
|
| 1 |
Ki = 9.333 nM
|
|
|
|
CP0375932
|
3-(2,6-dimethoxyphenyl)-N-[2-(2-phenylmethoxyphenoxy)ethyl]propan-1-amine
Show/Hide
|
C26H31NO4
|
1
|
| 1 |
Ki = 9.772 nM
|
|
|
|
CP0688479
|
2-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-1,4-dioxa-8lambda6-thiaspiro[4.5]decane-8,8-dione
Show/Hide
|
C19H28N2O5S
|
1
|
| 1 |
Ki = 9.772 nM
|
|
|
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CP0489482
|
8-[[(2S,4R)-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-2-phenyl-1,3-dioxolan-2-yl]methyl]-8-azaspiro[4.5]decane-7,9-dione
Show/Hide
|
C31H39N3O5
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0497240
|
2-phenoxy-N-[2-(2-phenylmethoxyphenoxy)ethyl]ethanamine
Show/Hide
|
C23H25NO3
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0763928
|
2-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-8-[4-(trifluoromethyl)benzoyl]-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
|
C27H32F3N3O4
|
1
|
| 1 |
Ki = 10.23 nM
|
|
|
|
CP0882783
|
(+)-6,7-dimethoxy-2-[(4aS,8aR)-4-(1H-pyrrol-2-ylcarbonyl)octahydroquinoxalin-1(2H)-yl]quinazolin-4-amine
Show/Hide
|
C23H28N6O3
|
1
|
| 1 |
Ki = 10.47 nM
|
|
|
|
CP0657012
|
8-Benzoyl-2-{[4-(2-methoxyphenyl)piperazin-1-yl]methyl}-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
|
C26H33N3O4
|
1
|
| 1 |
Ki = 10.72 nM
|
|
|
|
CP0460076
|
(S)-4-(3,4-Difluoro-phenyl)-1,3,6-trimethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid {3-[4-(4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide
Show/Hide
|
C28H33F3N4O2
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0867161
|
1-[3-(2,4-Dimethylphenoxy)propyl]-4-(2-methoxyphenyl)piperazine hydrochloride
Show/Hide
|
C22H31ClN2O2
|
1
|
| 1 |
Ki = 11 nM
|
|
|
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CP0904595
|
(R)-N-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-2-(2,6-dimethoxyphenoxy)ethanamine hydrochloride
Show/Hide
|
C19H24ClNO5
|
1
|
| 1 |
Ki = 11.22 nM
|
|
|
|
CP0118815
|
N-[[(3R)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-2-(2,6-dimethoxyphenoxy)ethanamine
Show/Hide
|
C19H23NO5
|
1
|
| 1 |
Ki = 11.22 nM
|
|
|
|
CP0846429
|
(R)-N-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-2-(2,6-dimethoxyphenoxy)ethanamine oxalate
Show/Hide
|
C21H25NO9
|
1
|
| 1 |
Ki = 11.22 nM
|
|
|
|
CP0408404
|
N-[[(3R)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-2-[(2-methoxy-5,6,7,8-tetrahydronaphthalen-1-yl)oxy]ethanamine;hydrochloride
Show/Hide
|
C22H27NO4
|
1
|
| 1 |
Ki = 11.48 nM
|
|
|
|
CP0411877
|
1-[[(2S,4R)-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-2-phenyl-1,3-dioxolan-2-yl]methyl]piperidin-2-one
Show/Hide
|
C27H35N3O4
|
1
|
| 1 |
Ki = 11.48 nM
|
|
|
|
CP0394897
|
2-methoxy-5-[(2R)-2-[[(2R,3S)-2-methyl-2,3-dihydro-1,4-benzodioxin-3-yl]methylamino]propyl]benzenesulfonamide
Show/Hide
|
C20H26N2O5S
|
1
|
| 1 |
Ki = 11.48 nM
|
|
|
|
CP0115843
|
[3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-1,4-dioxa-8-azaspiro[4.5]decan-8-yl]-pyrrolidin-2-ylmethanone
Show/Hide
|
C24H36N4O4
|
1
|
| 1 |
Ki = 11.75 nM
|
|
|
|
CP0147893
|
3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-N-phenyl-1,4-dioxa-8-azaspiro[4.5]decane-8-carboxamide
Show/Hide
|
C26H34N4O4
|
1
|
| 1 |
Ki = 12.02 nM
|
|
|
|
CP0415317
|
1-[[(2R,4R)-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-2-phenyl-1,3-dioxolan-2-yl]methyl]pyrrolidin-2-one
Show/Hide
|
C26H33N3O4
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0311688
|
N-tert-butyl-3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-1,4-dioxa-8-azaspiro[4.5]decane-8-carboxamide
Show/Hide
|
C24H38N4O4
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0397503
|
N-[1'-(2-naphthalen-1-ylethyl)-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl]-1-phenylmethanesulfonamide
Show/Hide
|
C32H32N2O4S
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0873149
|
1-(2-Methoxyphenyl)-4-{2-[2-(2,3,5-trimethylphenoxy)ethoxy]ethyl}piperazine dihydrochloride
Show/Hide
|
C24H36Cl2N2O3
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0864251
|
1-{2-[2-(Mesityloxy)ethoxy]ethyl}-4-(2-methoxyphenyl)piperazine dihydrochloride
Show/Hide
|
C24H36Cl2N2O3
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0408405
|
[(3R)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl-[2-(2-methoxy-5-phenylphenoxy)ethyl]azanium;chloride
Show/Hide
|
C24H25NO4
|
1
|
| 1 |
Ki = 16.22 nM
|
|
|
|
CP0912439
|
(R)-2-(2,6-dimethoxyphenoxy)-N-((8-methoxy-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)ethanamine hydrochloride
Show/Hide
|
C20H26ClNO6
|
1
|
| 1 |
Ki = 16.6 nM
|
|
|
|
CP0402212
|
N-[[(2R)-6,6-diphenyl-1,4-dioxan-2-yl]methyl]-2-(2-methoxyphenoxy)ethanamine
Show/Hide
|
C26H29NO4
|
2
|
| 1 |
Ki = 16.6 nM
|
|
|
| 2 |
Ki = 27.54 nM
|
|
|
|
CP0379280
|
2-[3-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]propoxy]benzamide
Show/Hide
|
C28H30N4O4S
|
1
|
| 1 |
Ki = 16.9 nM
|
|
|
|
CP0500849
|
N-[[(3R)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-2-[(6-methoxy-2,3-dihydro-1-benzofuran-7-yl)oxy]ethanamine;hydrochloride
Show/Hide
|
C20H24ClNO5
|
1
|
| 1 |
Ki = 16.98 nM
|
|
|
|
CP0068597
|
1-(2-methoxyphenyl)-4-(1,4,8-trioxaspiro[4.5]decan-3-ylmethyl)piperazine
Show/Hide
|
C19H28N2O4
|
1
|
| 1 |
Ki = 16.98 nM
|
|
|
|
CP0495611
|
1-[(4aR,8aS)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-2-naphthalen-2-ylethanone
Show/Hide
|
C30H33N5O3
|
1
|
| 1 |
Ki = 16.98 nM
|
|
|
|
CP0222921
|
N-(2-benzhydryloxyethyl)-2-phenoxyethanamine;oxalic acid
Show/Hide
|
C25H27NO6
|
1
|
| 1 |
Ki = 16.98 nM
|
|
|
|
CP0775946
|
2-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-8-(pyridin-2-yl)-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
|
C24H32N4O3
|
1
|
| 1 |
Ki = 17.78 nM
|
|
|
|
CP0912441
|
(R)-2-(2,6-dimethoxyphenoxy)-N-((8-fluoro-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)ethanamine hydrochloride
Show/Hide
|
C19H23ClFNO5
|
1
|
| 1 |
Ki = 18.2 nM
|
|
|
|
CP0464898
|
(3R)-N-[(3S)-1-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperidin-3-yl]-2,3-dihydro-1,4-benzodioxine-3-carboxamide
Show/Hide
|
C24H27N5O5
|
1
|
| 1 |
Ki = 18.2 nM
|
|
|
|
CP0037866
|
CAS_146714-97-8
Show/Hide
|
C25H34N4O2
|
1
|
| 1 |
Ki = 18.62 nM
|
|
|
|
CP0780574
|
N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinyl-cyclohexanecarboxamide tri hydrochloride
Show/Hide
|
C25H35ClN4O2
|
1
|
| 1 |
Ki = 18.62 nM
|
|
|
|
CP0115835
|
3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-8-methylsulfonyl-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
|
C20H31N3O5S
|
1
|
| 1 |
Ki = 18.62 nM
|
|
|
|
CP0848763
|
4-(3,4-Difluoro-phenyl)-2-oxo-6-trifluoromethyl-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid {3-[4-(4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide
Show/Hide
|
C26H26F6N4O2
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0394967
|
2-methoxy-5-[(2R)-2-[[(2S,3R)-2-methyl-2,3-dihydro-1,4-benzodioxin-3-yl]methylamino]propyl]benzenesulfonamide
Show/Hide
|
C20H26N2O5S
|
1
|
| 1 |
Ki = 19.05 nM
|
|
|
|
CP0390409
|
N-[(2,2-diphenyl-1,3-dioxolan-4-yl)methyl]-2-(2-methoxyphenoxy)ethanamine
Show/Hide
|
C25H27NO4
|
1
|
| 1 |
Ki = 19.5 nM
|
|
|
|
CP0750872
|
N-((2,2-diphenyl-1,3-dioxolan-4-yl)methyl)-2-(2-methoxyphenoxy)ethanamine oxalate
Show/Hide
|
C27H29NO8
|
2
|
| 1 |
Ki = 19.5 nM
|
|
|
| 2 |
Ki = 24.55 nM
|
|
|
|
CP0373939
|
N-[2-(2,6-dimethoxyphenyl)sulfinylethyl]-2-(2-phenylmethoxyphenoxy)ethanamine
Show/Hide
|
C25H29NO5S
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0802345
|
N-butyl-2-{[4-(2-methoxyphenyl)piperazin-1-yl]methyl}-1,4-dioxa-8-azaspiro[4.5]decane-8-carboxamide
Show/Hide
|
C24H38N4O4
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0395434
|
5,7-Dimethyl-3-{1-[4-(1,1,3-trioxo-1,3-dihydro-1lambda*6*-benzo[d]isothiazol-2-yl)-butyl]-piperidin-4-yl}-3H-benzooxazol-2-one
Show/Hide
|
C25H29N3O5S
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0395091
|
N-[1'-(2-naphthalen-1-ylethyl)-4-oxospiro[3H-chromene-2,4'-piperidine]-7-yl]methanesulfonamide
Show/Hide
|
C26H28N2O4S
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0402373
|
(S)-4-(3,4-Difluoro-phenyl)-1,6-dimethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid {3-[4-(4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide
Show/Hide
|
C27H31F3N4O2
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0890305
|
4-(3,4-Difluoro-phenyl)-2-oxo-6-trifluoromethyl-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid {3-[4-(2-cyano-phenyl)-piperidin-1-yl]-propyl}-amide
Show/Hide
|
C27H26F5N5O2
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0390410
|
N-[(2,2-diphenyl-1,3-oxathiolan-5-yl)methyl]-2-(2-methoxyphenoxy)ethanamine
Show/Hide
|
C25H27NO3S
|
1
|
| 1 |
Ki = 20.89 nM
|
|
|
|
CP0489497
|
1-[[(2S,4R)-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-2-phenyl-1,3-dioxolan-2-yl]methyl]piperidine-2,6-dione
Show/Hide
|
C27H33N3O5
|
1
|
| 1 |
Ki = 21.38 nM
|
|
|
|
CP0763926
|
8-(Furan-2-carbonyl)-2-{[4-(2-methoxyphenyl)piperazin-1-yl]methyl}-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
|
C24H31N3O5
|
1
|
| 1 |
Ki = 21.38 nM
|
|
|
|
CP0410713
|
[(4aR,8aS)-4-[4-(dipropylamino)-6,7-dimethoxyquinazolin-2-yl]-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-(furan-2-yl)methanone
Show/Hide
|
C29H39N5O4
|
1
|
| 1 |
Ki = 22.39 nM
|
|
|
|
CP0882785
|
(+)-6,7-dimethoxy-2-[(4aS,8aR)-4-(5-methyl-2-furoyl)octahydroquinoxalin-1(2H)-yl]quinazolin-4-amine
Show/Hide
|
C24H29N5O4
|
1
|
| 1 |
Ki = 23.44 nM
|
|
|
|
CP0892038
|
(S)-2-(2,6-dimethoxyphenoxy)-N-((5-methoxy-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)ethanamine hydrochloride
Show/Hide
|
C20H26ClNO6
|
1
|
| 1 |
Ki = 23.99 nM
|
|
|
|
CP0350499
|
N-[(2,2-diphenyl-1,3-dioxan-4-yl)methyl]-2-(2-methoxyphenoxy)ethanamine;oxalic acid
Show/Hide
|
C28H31NO8
|
1
|
| 1 |
Ki = 24.55 nM
|
|
|
|
CP0889459
|
(S)-2-(2,6-dimethoxyphenoxy)-N-((2,3,6,7,8,9-hexahydronaphtho[2,3-b][1,4]dioxin-2-yl)methyl)ethanaminium chloride
Show/Hide
|
C23H30ClNO5
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0882786
|
(+)-1-(5-{[(4aR,8aS)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)octahydroquinoxalin-1(2H)-yl]carbonyl}-2-furyl)ethanone
Show/Hide
|
C25H29N5O5
|
1
|
| 1 |
Ki = 25.7 nM
|
|
|
|
CP0415318
|
1-[[(2S,4R)-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-2-phenyl-1,3-dioxolan-2-yl]methyl]azepan-2-one
Show/Hide
|
C28H37N3O4
|
1
|
| 1 |
Ki = 26.92 nM
|
|
|
|
CP0894525
|
[(5,5-Diphenyloxolan-2-yl)methyl][2-(2-methoxyphenoxy)-ethyl]amine Oxalate Salt
Show/Hide
|
C28H31NO7
|
1
|
| 1 |
Ki = 26.92 nM
|
|
|
|
CP0872835
|
(+)-6,7-dimethoxy-2-[(4aS,8aR)-4-(5-methoxy-2-furoyl)octahydroquinoxalin-1(2H)-yl]quinazolin-4-amine
Show/Hide
|
C24H29N5O5
|
1
|
| 1 |
Ki = 27.54 nM
|
|
|
|
CP0414228
|
N-[(6,6-diphenyl-1,4-dioxan-2-yl)methyl]-2-(2-methoxyphenoxy)ethanamine
Show/Hide
|
C26H29NO4
|
1
|
| 1 |
Ki = 27.54 nM
|
|
|
|
CP0705393
|
{[(4R)-2,2-diphenyl-1,3-dioxolan-4-yl]methyl}(2-phenoxyethyl)amine oxalate
Show/Hide
|
C26H27NO7
|
1
|
| 1 |
Ki = 30.2 nM
|
|
|
|
CP0802344
|
8-Cyclohexanecarbonyl-2-{[4-(2-methoxyphenyl)piperazin-1-yl]methyl}-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
|
C26H39N3O4
|
1
|
| 1 |
Ki = 30.9 nM
|
|
|
|
CP0326120
|
N-[[(2S,4S)-2-benzhydryl-1,3-dioxolan-4-yl]methyl]-2-(2-methoxyphenoxy)ethanamine;oxalic acid
Show/Hide
|
C28H31NO8
|
1
|
| 1 |
Ki = 30.9 nM
|
|
|
|
CP0461008
|
1'-[2-(1-naphthyl)ethyl]spiro[2,3-dihydro-1H-indene-2,4'-(hexahydropyridine)]-1-one
Show/Hide
|
C25H25NO
|
1
|
| 1 |
Ki = 31 nM
|
|
|
|
CP0459890
|
N-[(9-amino-6,7-dimethoxy-1,2,3,4-tetrahydroacridin-3-yl)methyl]-3-(trifluoromethyl)benzamide;hydrochloride
Show/Hide
|
C24H25ClF3N3O3
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0404054
|
N-[[(3R)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-2-[(6-methoxy-2,3-dihydro-1H-indol-7-yl)oxy]ethanamine;dihydrochloride
Show/Hide
|
C20H26Cl2N2O4
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0154869
|
1-(2-methoxyphenyl)-4-(2-phenylethyl)piperazine
Show/Hide
|
C19H24N2O
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0558773
|
(3S)-N-[(3S)-1-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperidin-3-yl]-2,3-dihydro-1,4-benzodioxine-3-carboxamide
Show/Hide
|
C24H27N5O5
|
1
|
| 1 |
Ki = 33.11 nM
|
|
|
|
CP0847727
|
Carboxy-methanecarboxylate(2,2-diphenyl-[1,3]dioxolan-4-ylmethyl)-dimethyl-(2-phenoxy-ethyl)-ammonium
Show/Hide
|
C28H31NO7
|
1
|
| 1 |
Ki = 33.88 nM
|
|
|
|
CP0917489
|
(S)-N-((2,3-dihydronaphtho[2,3-b][1,4]dioxin-2-yl)methyl)-2-(2,6-dimethoxyphenoxy)ethanaminium chloride
Show/Hide
|
C23H26ClNO5
|
1
|
| 1 |
Ki = 33.88 nM
|
|
|
|
CP0230606
|
N-[(2,2-diphenyl-1,3-dioxan-5-yl)methyl]-2-(2-methoxyphenoxy)ethanamine;oxalic acid
Show/Hide
|
C28H31NO8
|
1
|
| 1 |
Ki = 33.88 nM
|
|
|
|
CP0373753
|
N-[(2,2-diphenyl-1,3-dithiolan-4-yl)methyl]-2-(2-methoxyphenoxy)ethanamine
Show/Hide
|
C25H27NO2S2
|
1
|
| 1 |
Ki = 35.48 nM
|
|
|
|
CP0853339
|
1-{2-[2-(2,3-Dimethylphenoxy)ethoxy]ethyl}-4-phenethylpiperazine dihydrochloride
Show/Hide
|
C24H36Cl2N2O2
|
1
|
| 1 |
Ki = 36 nM
|
|
|
|
CP0746429
|
N-((2,2-diphenyl-1,3-dioxolan-4-yl)methyl)-2-phenoxyethanamine oxalate
Show/Hide
|
C26H27NO7
|
1
|
| 1 |
Ki = 37.15 nM
|
|
|
|
CP0400291
|
N-[(2,2-diphenyl-1,3-dioxolan-4-yl)methyl]-2-phenoxyethanamine
Show/Hide
|
C24H25NO3
|
1
|
| 1 |
Ki = 37.15 nM
|
|
|
|
CP0394915
|
4,5,6,7-tetrafluoro-2-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)isoindoline-1,3-dione
Show/Hide
|
C27H29F4N3O3
|
1
|
| 1 |
Ki = 37.8 nM
|
|
|
|
CP0854275
|
cis-5-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-2,2-diphenylcyclopentan-1-ol Oxalate salt
Show/Hide
|
C31H36N2O6
|
1
|
| 1 |
Ki = 38.9 nM
|
|
|
|
CP0350497
|
N-[(2,2-diphenyl-1,3-dioxan-4-yl)methyl]-2-phenoxyethanamine;oxalic acid
Show/Hide
|
C27H29NO7
|
1
|
| 1 |
Ki = 38.9 nM
|
|
|
|
CP0859289
|
5-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-2,2-diphenylcyclopentan-1-one Oxalate Salt
Show/Hide
|
C31H34N2O6
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0406100
|
1-[[(2S,4R)-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-2-phenyl-1,3-dioxolan-2-yl]methyl]pyrrolidine-2,5-dione
Show/Hide
|
C26H31N3O5
|
1
|
| 1 |
Ki = 40.74 nM
|
|
|
|
CP0854276
|
trans-5-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-2,2-diphenylcyclopentan-1-ol Oxalate
Show/Hide
|
C31H36N2O6
|
1
|
| 1 |
Ki = 44.67 nM
|
|
|
|
CP0230607
|
N-(2-benzhydryloxyethyl)-2-(2-methoxyphenoxy)ethanamine;oxalic acid
Show/Hide
|
C26H29NO7
|
1
|
| 1 |
Ki = 44.67 nM
|
|
|
|
CP0439601
|
1'-[2-(1-naphthyl)ethyl]spiro[3,4-dihydro-1H-isochromene-3,4'-(hexahydropyridine)]-1-one
Show/Hide
|
C25H25NO2
|
1
|
| 1 |
Ki = 45 nM
|
|
|
|
CP0858962
|
(+)-6,7-dimethoxy-2-[(4aS,8aR)-4-(pyridin-2-ylcarbonyl)octahydroquinoxalin-1(2H)-yl]quinazolin-4-amine
Show/Hide
|
C24H28N6O3
|
1
|
| 1 |
Ki = 48.98 nM
|
|
|
|
CP0390411
|
N-[(2,2-diphenyl-1,3-dioxolan-4-yl)methyl]-3-(2-methoxyphenyl)propan-1-amine
Show/Hide
|
C26H29NO3
|
1
|
| 1 |
Ki = 48.98 nM
|
|
|
|
CP0688481
|
2-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
|
C19H29N3O3
|
1
|
| 1 |
Ki = 48.98 nM
|
|
|
|
CP0356932
|
2-[(2S,4R)-2-benzhydryl-1,3-dioxolan-4-yl]-N-[2-(2-methoxyphenoxy)ethyl]ethanamine;oxalic acid
Show/Hide
|
C29H33NO8
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0397435
|
1'-[2-(1-naphthyl)ethyl]spiro[3,4-dihydro-2H-chromene-2,4'-(hexahydropyridine)]-4-one
Show/Hide
|
C25H25NO2
|
1
|
| 1 |
Ki = 53 nM
|
|
|
|
CP0859341
|
[(5,5-Diphenyloxolan-2-yl)methyl](2-phenoxyethyl)amine Oxalate Salt
Show/Hide
|
C27H29NO6
|
1
|
| 1 |
Ki = 53.7 nM
|
|
|
|
CP0232093
|
1-[3-(4-phenylpiperazin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C22H27N3O
|
1
|
| 1 |
Ki = 53.7 nM
|
|
|
|
CP0460106
|
1'-[2-(1-naphthyl)ethyl]spiro[3,4-dihydro-2H-chromene-2,4'-(hexahydropyridine)]
Show/Hide
|
C25H27NO
|
1
|
| 1 |
Ki = 56 nM
|
|
|
|
CP0445299
|
1-(2-methoxyphenyl)-4-(1-oxa-4-thiaspiro[4.5]decan-2-ylmethyl)piperazine
Show/Hide
|
C20H30N2O2S
|
1
|
| 1 |
Ki = 57.54 nM
|
|
|
|
CP0230604
|
2-(2,2-diphenyl-1,3-dioxolan-4-yl)-N-(2-phenoxyethyl)ethanamine;oxalic acid
Show/Hide
|
C27H29NO7
|
1
|
| 1 |
Ki = 58.88 nM
|
|
|
|
CP0131832
|
1-[3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-1,4-dioxa-8-azaspiro[4.5]decan-8-yl]ethanone
Show/Hide
|
C21H31N3O4
|
1
|
| 1 |
Ki = 60.26 nM
|
|
|
|
CP0204599
|
2-[(2S,4S)-2-benzhydryl-1,3-dioxolan-4-yl]-N-[2-(2-methoxyphenoxy)ethyl]ethanamine;oxalic acid
Show/Hide
|
C29H33NO8
|
1
|
| 1 |
Ki = 60.26 nM
|
|
|
|
CP0949094
|
(S)-2-[((2-(2-methoxy-1-naphthoxy)ethyl)amino)methyl]-2,3,6,7,8,9-hexahydronaphtho[2,3-b][1,4]dioxine hydrochloride
Show/Hide
|
C26H30ClNO4
|
1
|
| 1 |
Ki = 66.07 nM
|
|
|
|
CP0943168
|
(R)-2-[((2-(2,6-Dimethoxyphenoxy)ethyl)amino)methyl]-8-hydroxy-1,4-benzodioxane hydrochloride
Show/Hide
|
C19H24ClNO6
|
1
|
| 1 |
Ki = 66.07 nM
|
|
|
|
CP0432887
|
1'-[2-(1-naphthyl)ethyl]spiro[2H-chromene-2,4'-(hexahydropyridine)]
Show/Hide
|
C25H25NO
|
1
|
| 1 |
Ki = 71 nM
|
|
|
|
CP0435761
|
N-[[(2R)-5,5-diphenyl-1,4-dioxan-2-yl]methyl]-2-(2-methoxyphenoxy)ethanamine
Show/Hide
|
C26H29NO4
|
1
|
| 1 |
Ki = 74.13 nM
|
|
|
|
CP0496434
|
[(4aS,8aS)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-(2,3-dihydro-1,4-benzodioxin-3-yl)methanone
Show/Hide
|
C27H31N5O5
|
1
|
| 1 |
Ki = 81.28 nM
|
|
|
|
CP0366049
|
2-benzhydryloxy-3-[2-(2-methoxyphenoxy)ethylamino]propan-1-ol;oxalic acid
Show/Hide
|
C27H31NO8
|
1
|
| 1 |
Ki = 83.18 nM
|
|
|
|
CP0126495
|
N-[(9-amino-6,7-dimethoxy-1,2,3,4-tetrahydroacridin-3-yl)methyl]-4-(trifluoromethyl)benzamide
Show/Hide
|
C24H24F3N3O3
|
1
|
| 1 |
Ki = 85.11 nM
|
|
|
|
CP0373784
|
2-(2,3-dimethoxyphenoxy)-N-[(2,2-diphenyl-1,3-dioxolan-4-yl)methyl]ethanamine
Show/Hide
|
C26H29NO5
|
1
|
| 1 |
Ki = 85.11 nM
|
|
|
|
CP0862493
|
(S)-2-[((2-(2-methoxy-4-phenylphenoxy)ethyl)amino)methyl]-1,4-benzodioxane hydrochloride
Show/Hide
|
C24H26ClNO4
|
1
|
| 1 |
Ki = 87.1 nM
|
|
|
|
CP0371702
|
2-(2-methoxyphenoxy)-N-[[(2R,6R)-6-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C20H25NO4
|
1
|
| 1 |
Ki = 87.1 nM
|
|
|
|
CP0378503
|
2-(2,6-dimethoxyphenoxy)-N-[[(2R)-5,5-diphenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C27H31NO5
|
1
|
| 1 |
Ki = 89.13 nM
|
|
|
|
CP0471912
|
2-[(2S,4S)-2-benzhydryl-1,3-dioxolan-4-yl]-N-(2-phenoxyethyl)ethanamine;oxalic acid
Show/Hide
|
C28H31NO7
|
1
|
| 1 |
Ki = 89.13 nM
|
|
|
|
CP0522627
|
3-{1-[4-(1,1,3-Trioxo-1,3-dihydro-1lambda*6*-benzo[d]isothiazol-2-yl)-butyl]-piperidin-4-yl}-5,6,7,8-tetrahydro-3H-naphtho[2,3-d]oxazol-2-one
Show/Hide
|
C27H31N3O5S
|
1
|
| 1 |
Ki = 90 nM
|
|
|
|
CP0382790
|
N-[(2,2-diphenyl-1,3-dioxolan-4-yl)methyl]-2-(3-methoxyphenoxy)ethanamine
Show/Hide
|
C25H27NO4
|
1
|
| 1 |
Ki = 91.2 nM
|
|
|
|
CP0121063
|
1-(1,4-dioxaspiro[4.5]decan-3-ylmethyl)-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C20H30N2O3
|
1
|
| 1 |
Ki = 91.2 nM
|
|
|
|
CP0873148
|
1-[3-(4-Chloro-3-methylphenoxy)propyl]-4-phenylpiperazine dihydrochloride
Show/Hide
|
C20H27Cl3N2O
|
1
|
| 1 |
Ki = 93 nM
|
|
|
|
CP0393190
|
N-[(9-amino-6,7-dimethoxy-1,2,3,4-tetrahydroacridin-3-yl)methyl]furan-2-carboxamide
Show/Hide
|
C21H23N3O4
|
1
|
| 1 |
Ki = 95.5 nM
|
|
|
|
CP0453599
|
2-(2,6-dimethoxyphenoxy)-N-[[(3R)-2,3,6,7,8,9-hexahydrobenzo[g][1,4]benzodioxin-3-yl]methyl]ethanamine;hydrochloride
Show/Hide
|
C23H29NO5
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0373783
|
2-(2,6-dimethoxyphenoxy)-N-[(2,2-diphenyl-1,3-dioxolan-4-yl)methyl]ethanamine
Show/Hide
|
C26H29NO5
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0485314
|
N-[[(3R)-2,3-dihydrobenzo[g][1,4]benzodioxin-3-yl]methyl]-2-(2,6-dimethoxyphenoxy)ethanamine;hydrochloride
Show/Hide
|
C23H26ClNO5
|
1
|
| 1 |
Ki = 102.33 nM
|
|
|
|
CP0854278
|
trans-5-({[2-(2-Methoxyphenoxy)ethyl]amino}methyl)-2,2-diphenylcyclopentan-1-ol Oxalate Salt
Show/Hide
|
C29H33NO7
|
1
|
| 1 |
Ki = 109.65 nM
|
|
|
|
CP0566392
|
N-[(3R)-1-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperidin-3-yl]furan-2-carboxamide
Show/Hide
|
C20H23N5O4
|
1
|
| 1 |
Ki = 109.65 nM
|
|
|
|
CP0396050
|
2-(2-chlorophenoxy)-N-[(6,6-diphenyl-1,4-dioxan-2-yl)methyl]ethanamine
Show/Hide
|
C25H26ClNO3
|
1
|
| 1 |
Ki = 114.82 nM
|
|
|
|
CP0373781
|
N-[(2,2-diphenyl-1,3-dioxolan-4-yl)methyl]-2-(2-methylphenoxy)ethanamine
Show/Hide
|
C25H27NO3
|
1
|
| 1 |
Ki = 117.49 nM
|
|
|
|
CP0389457
|
N-[(6,6-diphenyl-1,4-dioxan-2-yl)methyl]-2-(2-nitrophenoxy)ethanamine
Show/Hide
|
C25H26N2O5
|
1
|
| 1 |
Ki = 117.49 nM
|
|
|
|
CP0482650
|
2-[[(3R)-1-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperidin-3-yl]amino]naphthalene-1,4-dione
Show/Hide
|
C25H25N5O4
|
1
|
| 1 |
Ki = 120.23 nM
|
|
|
|
CP0459292
|
N-[[(2S,4S)-2-benzhydryl-1,3-dioxolan-4-yl]methyl]-2-phenoxyethanamine;oxalic acid
Show/Hide
|
C27H29NO7
|
1
|
| 1 |
Ki = 120.23 nM
|
|
|
|
CP0751060
|
{[(4S)-2,2-diphenyl-1,3-dioxolan-4-yl]methyl}(2-phenoxyethyl)amine oxalate
Show/Hide
|
C26H27NO7
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0409005
|
N-[[(2R)-6,6-diphenyl-1,4-dioxan-2-yl]methyl]-2-phenoxyethanamine
Show/Hide
|
C25H27NO3
|
2
|
| 1 |
Ki = 128.82 nM
|
|
|
| 2 |
Ki = 169.82 nM
|
|
|
|
CP0117550
|
6,7-Dibromo-3-[(2S,5R)-5-(6-bromo-1H-indol-3-yl)-4-methyl-piperazin-2-yl]-1H-indol-4-ol
Show/Hide
|
C21H19Br3N4O
|
1
|
| 1 |
Ki = 140 nM
|
|
|
|
CP0350498
|
2-benzhydryloxy-3-(2-phenoxyethylamino)propan-1-ol;oxalic acid
Show/Hide
|
C26H29NO7
|
1
|
| 1 |
Ki = 141.25 nM
|
|
|
|
CP0436902
|
4-Methyl-3-{1-[4-(1,1,3-trioxo-1,3-dihydro-1lambda*6*-benzo[d]isothiazol-2-yl)-butyl]-piperidin-4-yl}-3H-benzooxazol-2-one
Show/Hide
|
C24H27N3O5S
|
1
|
| 1 |
Ki = 147 nM
|
|
|
|
CP0037227
|
7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
|
C16H25NO
|
3
|
| 1 |
Ki = 151.36 nM
|
|
|
| 2 |
Ki > 1000 nM
|
|
|
| 3 |
Ki < 1000000 nM
|
|
|
|
CP0396049
|
N-[(6,6-diphenyl-1,4-dioxan-2-yl)methyl]-2-pyridin-2-yloxyethanamine
Show/Hide
|
C24H26N2O3
|
1
|
| 1 |
Ki = 154.88 nM
|
|
|
|
CP0402211
|
2-(2-methoxyphenoxy)-N-[[(2R,5S)-5-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C20H25NO4
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0440492
|
N-[(9-amino-6,7-dimethoxy-2,3-dihydro-1H-cyclopenta[b]quinolin-2-yl)methyl]furan-2-carboxamide
Show/Hide
|
C20H21N3O4
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0384764
|
2-(2,6-dimethoxyphenoxy)-N-[[(2R)-6,6-diphenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C27H31NO5
|
2
|
| 1 |
Ki = 165.96 nM
|
|
|
| 2 |
Ki = 338.84 nM
|
|
|
|
CP0408073
|
N-[(6,6-diphenyl-1,4-dioxan-2-yl)methyl]-2-phenoxyethanamine
Show/Hide
|
C25H27NO3
|
1
|
| 1 |
Ki = 169.82 nM
|
|
|
|
CP0389458
|
N-[(6,6-diphenyl-1,4-dioxan-2-yl)methyl]-2-(2-methylphenoxy)ethanamine
Show/Hide
|
C26H29NO3
|
1
|
| 1 |
Ki = 169.82 nM
|
|
|
|
CP0350496
|
2-[(2S,4R)-2-benzhydryl-1,3-dioxolan-4-yl]-N-(2-phenoxyethyl)ethanamine;oxalic acid
Show/Hide
|
C28H31NO7
|
1
|
| 1 |
Ki = 169.82 nM
|
|
|
|
CP0155898
|
N-[[(3S)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-2-[(6-methoxy-1H-indol-7-yl)oxy]ethanamine
Show/Hide
|
C20H22N2O4
|
1
|
| 1 |
Ki = 177.83 nM
|
|
|
|
CP0503951
|
N-(1,4-dithiaspiro[4.5]decan-3-ylmethyl)-2-(2-methoxyphenoxy)ethanamine
Show/Hide
|
C18H27NO2S2
|
1
|
| 1 |
Ki = 186.21 nM
|
|
|
|
CP0412413
|
2-[(3S)-3-aminopiperidin-1-yl]-6,7-dimethoxyquinazolin-4-amine
Show/Hide
|
C15H21N5O2
|
1
|
| 1 |
Ki = 190.55 nM
|
|
|
|
CP0396051
|
2-[2-[(6,6-diphenyl-1,4-dioxan-2-yl)methylamino]ethoxy]phenol
Show/Hide
|
C25H27NO4
|
1
|
| 1 |
Ki = 194.98 nM
|
|
|
|
CP0378504
|
2-(2-methoxyphenoxy)-N-[[(2R,6S)-6-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C20H25NO4
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0468298
|
1-(1,4-dithiaspiro[4.5]decan-3-ylmethyl)-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C20H30N2OS2
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0374257
|
N-[[(2R)-5,5-diphenyl-1,4-dioxan-2-yl]methyl]-2-phenoxyethanamine
Show/Hide
|
C25H27NO3
|
1
|
| 1 |
Ki = 223.87 nM
|
|
|
|
CP0446804
|
1-[(4aR,8aS)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]ethanone
Show/Hide
|
C20H27N5O3
|
1
|
| 1 |
Ki = 223.87 nM
|
|
|
|
CP0464374
|
N-(1,4-dioxaspiro[4.5]decan-3-ylmethyl)-2-(2-methoxyphenoxy)ethanamine
Show/Hide
|
C18H27NO4
|
1
|
| 1 |
Ki = 229.09 nM
|
|
|
|
CP0522904
|
N-[[(3R)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-2-(2-methoxy-4-phenylphenoxy)ethanamine;hydrochloride
Show/Hide
|
C24H25NO4
|
1
|
| 1 |
Ki = 234.42 nM
|
|
|
|
CP0396500
|
N-[[(2S)-6,6-diphenyl-1,4-dioxan-2-yl]methyl]-2-(2-methoxyphenoxy)ethanamine
Show/Hide
|
C26H29NO4
|
1
|
| 1 |
Ki = 257.04 nM
|
|
|
|
CP0116478
|
1-[3-(4-benzylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C24H30N2O
|
1
|
| 1 |
Ki = 257.04 nM
|
|
|
|
CP0503955
|
2-(2-methoxyphenoxy)-N-(1-oxa-4-thiaspiro[4.5]decan-2-ylmethyl)ethanamine
Show/Hide
|
C18H27NO3S
|
1
|
| 1 |
Ki = 269.15 nM
|
|
|
|
CP0389448
|
N-[(6,6-diphenyl-1,4-dioxan-2-yl)methyl]-2-[2-(methoxymethoxy)phenoxy]ethanamine
Show/Hide
|
C27H31NO5
|
1
|
| 1 |
Ki = 281.84 nM
|
|
|
|
CP0460833
|
N-[(9-amino-6,7-dimethoxy-1,2,3,4-tetrahydroacridin-3-yl)methyl]-2-(trifluoromethyl)benzamide
Show/Hide
|
C24H24F3N3O3
|
1
|
| 1 |
Ki = 288.4 nM
|
|
|
|
CP0347659
|
N-[(2,2-diphenyl-1,3-dioxan-5-yl)methyl]-2-phenoxyethanamine;oxalic acid
Show/Hide
|
C27H29NO7
|
1
|
| 1 |
Ki = 288.4 nM
|
|
|
|
CP0373782
|
2-(3,5-dimethoxyphenoxy)-N-[(2,2-diphenyl-1,3-dioxolan-4-yl)methyl]ethanamine
Show/Hide
|
C26H29NO5
|
1
|
| 1 |
Ki = 302 nM
|
|
|
|
CP0512065
|
N-[[(3R)-2,3,6,7,8,9-hexahydrobenzo[g][1,4]benzodioxin-3-yl]methyl]-2-(2-methoxynaphthalen-1-yl)oxyethanamine;hydrochloride
Show/Hide
|
C26H29NO4
|
1
|
| 1 |
Ki = 323.59 nM
|
|
|
|
CP0415219
|
2-(2,6-dimethoxyphenoxy)-N-[(6,6-diphenyl-1,4-dioxan-2-yl)methyl]ethanamine
Show/Hide
|
C27H31NO5
|
1
|
| 1 |
Ki = 338.84 nM
|
|
|
|
CP0426667
|
1-[[(2R)-3,3-diphenyl-1,4-dioxan-2-yl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C28H32N2O3
|
1
|
| 1 |
Ki = 354.81 nM
|
|
|
|
CP0714031
|
SID50105948
Show/Hide
|
C22H33Cl2N3O3
|
1
|
| 1 |
Ki = 380.19 nM
|
|
|
|
CP0439399
|
2-phenoxy-N-[[(2R,6R)-6-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C19H23NO3
|
1
|
| 1 |
Ki = 407.38 nM
|
|
|
|
CP0361338
|
N-[[(2S,4R)-2-benzhydryl-1,3-dioxolan-4-yl]methyl]-2-phenoxyethanamine;oxalic acid
Show/Hide
|
C27H29NO7
|
1
|
| 1 |
Ki = 426.58 nM
|
|
|
|
CP0378505
|
2-(2-methoxyphenoxy)-N-[[(2R,5R)-5-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C20H25NO4
|
1
|
| 1 |
Ki = 436.52 nM
|
|
|
|
CP0477118
|
N-[[(2S)-6,6-diphenyl-1,4-dioxan-2-yl]methyl]-2-phenoxyethanamine
Show/Hide
|
C25H27NO3
|
1
|
| 1 |
Ki = 436.52 nM
|
|
|
|
CP0444051
|
N-[[(3R)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-2-[(6-methoxy-1H-indol-7-yl)oxy]ethanamine
Show/Hide
|
C20H22N2O4
|
1
|
| 1 |
Ki = 436.52 nM
|
|
|
|
CP0232092
|
1-[3-(4-butylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C21H32N2O
|
1
|
| 1 |
Ki = 436.52 nM
|
|
|
|
CP0374168
|
2-(2,6-dimethoxyphenoxy)-N-[[(2R,6S)-6-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C21H27NO5
|
1
|
| 1 |
Ki = 467.74 nM
|
|
|
|
CP0373751
|
N-[(2,2-diphenyl-1,3-dioxolan-4-yl)methyl]-2-(2-phenylphenoxy)ethanamine
Show/Hide
|
C30H29NO3
|
1
|
| 1 |
Ki = 489.78 nM
|
|
|
|
CP0425302
|
6-Methoxy-3-{1-[4-(1,1,3-trioxo-1,3-dihydro-1lambda*6*-benzo[d]isothiazol-2-yl)-butyl]-piperidin-4-yl}-3H-benzooxazol-2-one
Show/Hide
|
C24H27N3O6S
|
1
|
| 1 |
Ki = 499 nM
|
|
|
|
CP0863070
|
4-(3,4-Difluoro-phenyl)-2-oxo-6-trifluoromethyl-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid [3-(3',4',5',6'-tetrahydro-2'H-[2,4']bipyridinyl-1'-yl)-propyl]-amide
Show/Hide
|
C25H26F5N5O2
|
1
|
| 1 |
Ki = 500 nM
|
|
|
|
CP0371704
|
2-(2,6-dimethoxyphenoxy)-N-[[(2R,5S)-5-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C21H27NO5
|
1
|
| 1 |
Ki = 512.86 nM
|
|
|
|
CP0384754
|
2-phenoxy-N-[[(2R,5S)-5-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C19H23NO3
|
1
|
| 1 |
Ki = 537.03 nM
|
|
|
|
CP0465335
|
6-Bromo-3-[2-(1H-indol-3-yl)-1H-imidazol-4-yl]-1H-indole
Show/Hide
|
C19H13BrN4
|
1
|
| 1 |
Ki = 550 nM
|
|
|
|
CP0380720
|
6-Bromo-3-[4-(1H-indol-3-yl)-1H-imidazol-2-yl]-1H-indole
Show/Hide
|
C19H13BrN4
|
1
|
| 1 |
Ki = 770 nM
|
|
|
|
CP0902025
|
1-{2-[2-(Mesityloxy)ethoxy]ethyl}-4-phenethylpiperazine dihydrochloride
Show/Hide
|
C25H38Cl2N2O2
|
1
|
| 1 |
Ki = 772 nM
|
|
|
|
CP0511048
|
1'-[2-(2-pyridyl)ethyl]spiro[3,4-dihydro-2H-chromene-2,4'-(hexahydropyridine)]-4-one
Show/Hide
|
C20H22N2O2
|
1
|
| 1 |
Ki = 793 nM
|
|
|
|
CP0860647
|
(R)-2-(2,6-dimethoxyphenoxy)-N-((5-methoxy-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)ethanamine hydrochloride
Show/Hide
|
C20H26ClNO6
|
1
|
| 1 |
Ki = 812.83 nM
|
|
|
|
CP0848345
|
Carboxy-methanecarboxylate(2,2-diphenyl-[1,3]dioxolan-4-ylmethyl)-methyl-(2-phenoxy-ethyl)-ammonium
Show/Hide
|
C27H29NO7
|
1
|
| 1 |
Ki = 831.76 nM
|
|
|
|
CP0483388
|
3-[[2-(2,6-dimethoxyphenoxy)ethylamino]methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroacridin-9-amine
Show/Hide
|
C26H33N3O5
|
1
|
| 1 |
Ki = 977.24 nM
|
|
|
|
CP0356931
|
N-[[(2S,4R)-2-benzhydryl-1,3-dioxolan-4-yl]methyl]-2-(2-methoxyphenoxy)ethanamine;oxalic acid
Show/Hide
|
C28H31NO8
|
1
|
| 1 |
Ki = 977.24 nM
|
|
|
|
CP0409412
|
2-Oxo-3-{1-[4-(1,1,3-trioxo-1,3-dihydro-1lambda*6*-benzo[d]isothiazol-2-yl)-butyl]-piperidin-4-yl}-2,3-dihydro-benzooxazole-6-carboxylic acid methyl ester
Show/Hide
|
C25H27N3O7S
|
1
|
| 1 |
Ki = 1033 nM
|
|
|
|
CP0135923
|
CHEBI:6956
Show/Hide
|
C23H30N2O4
|
1
|
| 1 |
Ki = 1340 nM
|
|
|
|
CP0397434
|
N-[4-oxo-1'-(2-pyridin-2-ylethyl)spiro[3H-chromene-2,4'-piperidine]-7-yl]methanesulfonamide
Show/Hide
|
C21H25N3O4S
|
1
|
| 1 |
Ki = 1670 nM
|
|
|
|
CP0415073
|
3-[[2-(2,6-dimethoxyphenoxy)ethylamino]methyl]-6,7-dimethoxy-2,3,4,10-tetrahydro-1H-acridin-9-one
Show/Hide
|
C26H32N2O6
|
1
|
| 1 |
Ki = 1698.24 nM
|
|
|
|
CP0853338
|
1-[3-(Mesityloxy)propyl]-4-(4-methoxyphenyl)piperazine dihydrochloride
Show/Hide
|
C23H34Cl2N2O2
|
1
|
| 1 |
Ki = 2117 nM
|
|
|
|
CP0466612
|
6-bromo-3-[4-(6-bromo-1H-3-indolyl)-1H-2-imidazolyl]-1H-indole
Show/Hide
|
C19H12Br2N4
|
1
|
| 1 |
Ki = 2140 nM
|
|
|
|
CP0382852
|
N-[(6,7-dimethoxy-9-oxo-2,3,4,10-tetrahydro-1H-acridin-3-yl)methyl]furan-2-carboxamide
Show/Hide
|
C21H22N2O5
|
1
|
| 1 |
Ki = 2570.4 nM
|
|
|
|
CP0250631
|
[5-(6-bromo-1H-indol-3-yl)-1H-imidazol-2-yl]-(6-hydroxy-1H-indol-3-yl)methanone
Show/Hide
|
C20H13BrN4O2
|
1
|
| 1 |
Ki = 12590 nM
|
|
|
|
CP0374167
|
2-phenoxy-N-[[(2R,6S)-6-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C19H23NO3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0423054
|
2-(2,6-dimethoxyphenoxy)-N-[[(2R,5R)-5-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C21H27NO5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0435760
|
2-phenoxy-N-[[(2R,5R)-5-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C19H23NO3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0439400
|
2-(2,6-dimethoxyphenoxy)-N-[[(2R,6R)-6-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C21H27NO5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0373752
|
N-[(2,2-diphenyl-1,3-dioxolan-4-yl)methyl]-2-(4-phenylphenoxy)ethanamine
Show/Hide
|
C30H29NO3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0382788
|
2-(3,4-dimethoxyphenoxy)-N-[(2,2-diphenyl-1,3-dioxolan-4-yl)methyl]ethanamine
Show/Hide
|
C26H29NO5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0400292
|
N-[(2,2-diphenyl-1,3-dioxolan-4-yl)methyl]-2-(3-phenylphenoxy)ethanamine
Show/Hide
|
C30H29NO3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0854273
|
5-{[(2-Phenoxyethyl)amino]methyl}-2,2-diphenylcyclopentan-1-one Oxalate Salt
Show/Hide
|
C28H29NO6
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0854274
|
trans-5-{[(2-Phenoxyethyl)amino]methyl}-2,2-diphenylcyclopentan-1-ol Oxalate Salt
Show/Hide
|
C28H31NO6
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0854277
|
5-({[2-(2-Methoxyphenoxy)ethyl]amino}methyl)-2,2-diphenylcyclopentan-1-one Oxalate Salt
Show/Hide
|
C29H31NO7
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0859496
|
cis-5-{[(2-Phenoxyethyl)amino]methyl}-2,2-diphenylcyclopentan-1-ol Oxalate Salt
Show/Hide
|
C28H31NO6
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0414234
|
2-(2,6-dimethoxyphenoxy)-N-[[(2S)-6,6-diphenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C27H31NO5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0763927
|
2,2,2-Trifluoro-1-(2-{[4-(2-methoxyphenyl)piperazin-1-yl]methyl}-1,4-dioxa-8-azaspiro[4.5]decan-8-yl)ethan-1-one
Show/Hide
|
C21H28F3N3O4
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0468296
|
N-(1,4-dioxaspiro[4.5]decan-3-ylmethyl)-2-phenoxyethanamine
Show/Hide
|
C17H25NO3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0500267
|
2-(2,6-dimethoxyphenoxy)-N-(1,4-dioxaspiro[4.5]decan-3-ylmethyl)ethanamine
Show/Hide
|
C19H29NO5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0500270
|
N-(1-oxa-4-thiaspiro[4.5]decan-2-ylmethyl)-2-phenoxyethanamine
Show/Hide
|
C17H25NO2S
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0500278
|
N-(1,4-dithiaspiro[4.5]decan-3-ylmethyl)-2-phenoxyethanamine
Show/Hide
|
C17H25NOS2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0386946
|
2-[(3R)-3-aminopiperidin-1-yl]-6,7-dimethoxyquinazolin-4-amine
Show/Hide
|
C15H21N5O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0464899
|
(3S)-N-[(3R)-1-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperidin-3-yl]-2,3-dihydro-1,4-benzodioxine-3-carboxamide
Show/Hide
|
C24H27N5O5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0464900
|
(3R)-N-[(3R)-1-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperidin-3-yl]-2,3-dihydro-1,4-benzodioxine-3-carboxamide
Show/Hide
|
C24H27N5O5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0402933
|
2-(2-methoxyphenoxy)-N-[[(2R,3S)-3-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C20H25NO4
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0416975
|
2-(2,6-dimethoxyphenoxy)-N-[[(2R,3R)-3-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C21H27NO5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0421814
|
N-[(3,3-diphenyl-1,4-dioxan-2-yl)methyl]-2-phenoxyethanamine
Show/Hide
|
C25H27NO3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0421815
|
1-(2-methoxyphenyl)-4-[(2-phenyl-1,4-dioxan-2-yl)methyl]piperazine
Show/Hide
|
C22H28N2O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0421816
|
1-(2-methoxyphenyl)-4-[[(2R,3S)-3-phenyl-1,4-dioxan-2-yl]methyl]piperazine
Show/Hide
|
C22H28N2O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0421818
|
2-phenoxy-N-[(2-phenyl-1,4-dioxan-2-yl)methyl]ethanamine
Show/Hide
|
C19H23NO3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0421820
|
2-(2-methoxyphenoxy)-N-[(2-phenyl-1,4-dioxan-2-yl)methyl]ethanamine
Show/Hide
|
C20H25NO4
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0421821
|
2-(2-methoxyphenoxy)-N-[[(2R,3R)-3-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C20H25NO4
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0434677
|
2-(2,6-dimethoxyphenoxy)-N-[(3,3-diphenyl-1,4-dioxan-2-yl)methyl]ethanamine
Show/Hide
|
C27H31NO5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0434680
|
2-(2,6-dimethoxyphenoxy)-N-[(2-phenyl-1,4-dioxan-2-yl)methyl]ethanamine
Show/Hide
|
C21H27NO5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0484174
|
2-phenoxy-N-[[(2R,3R)-3-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C19H23NO3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0484175
|
2-phenoxy-N-[[(2R,3S)-3-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C19H23NO3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0535381
|
N-[(3,3-diphenyl-1,4-dioxan-2-yl)methyl]-2-(2-methoxyphenoxy)ethanamine
Show/Hide
|
C26H29NO4
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0538009
|
2-(2,6-dimethoxyphenoxy)-N-[[(2R,3S)-3-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C21H27NO5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0538010
|
1-(2-methoxyphenyl)-4-[[(2R,3R)-3-phenyl-1,4-dioxan-2-yl]methyl]piperazine
Show/Hide
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C22H28N2O3
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1
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| 1 |
Ki > 1000 nM
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CP0448770
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N-[4-oxo-1'-(2-pyridin-2-ylethyl)spiro[3H-chromene-2,4'-piperidine]-6-yl]methanesulfonamide
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C21H25N3O4S
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1
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| 1 |
Ki > 2000 nM
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