General Information of the Compound
| Compound ID |
CP0386946
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| Compound Name |
2-[(3R)-3-aminopiperidin-1-yl]-6,7-dimethoxyquinazolin-4-amine
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| Structure |
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| Formula |
C15H21N5O2
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| Molecular Weight |
303.366
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| Canonical SMILES |
COc1cc2nc(nc(N)c2cc1OC)N1CCC[C@@H](N)C1
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| InChI |
InChI=1S/C15H21N5O2/c1-21-12-6-10-11(7-13(12)22-2)18-15(19-14(10)17)20-5-3-4-9(16)8-20/h6-7,9H,3-5,8,16H2,1-2H3,(H2,17,18,19)/t9-/m1/s1
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| InChIKey |
NZORUWSOGKMFNY-SECBINFHSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01089, Alpha-1A adrenergic receptor
Protein ID: PT01007, Alpha-1B adrenergic receptor
Protein ID: PT01004, Alpha-1D adrenergic receptor