Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2,3-dihydro-1,4-benzodioxin-3-ylmethyl-[2-(2,6-dimethoxyphenoxy)ethyl]amine;hydrochloride
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 PubChem ID
CID: 5685
SID: 14778240
Canonical SMILES
COc1cccc(OC)c1OCCNCC1COc2ccccc2O1
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Compound Formula C19H23NO5
Compound Structure
Protein Name
 Protein Info 
Alpha-1A adrenergic receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Adrenergic receptor
Uniprot ID
P35348
Gene Name
ADRA1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
Ki = 0.16 nM
   TI
   LI
   LO
   TS
2
Ki = 0.4266 nM
   TI
   LI
   LO
   TS
3
Ki = 0.97174 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.1585 nM
2 Ki = 0.37 nM
3 Ki = 0.4266 nM