Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT06402 , Short transient receptor potential channel 6
 Protein Info 
Gene Name TRPC6
Organism Mus musculus, Mouse
Protein Classification Ion channel
Uniprot ID Q61143
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT06402
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0386836
 Compound Info 
CHEMBL4085233
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C22H23F3N4O3
  2
1
EC50 = 890 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
EC50 = 1385 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0386837
 Compound Info 
ethyl 4-[3-(4-fluorophenyl)-2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carboxylate
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C21H23FN4O3
  4
1
EC50 = 1400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
EC50 = 2500 nM
 Bioactivity Info 
   TI
   LI
   LO
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3
EC50 = 4660 nM
 Bioactivity Info 
   TI
   LI
   LO
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4
EC50 = 7200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0519446
 Compound Info 
ethyl 4-[2-methyl-3-(4-nitrophenyl)-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carboxylate
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C21H23N5O5
  1
1
EC50 = 2000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0386835
 Compound Info 
benzyl 4-[3-(4-chlorophenyl)-2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carboxylate
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C26H25ClN4O3
  2
1
EC50 = 2050 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
EC50 = 7790 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0393949
 Compound Info 
CHEMBL4060400
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C26H25FN4O3
  2
1
EC50 = 3240 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
EC50 = 3910 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0564251
 Compound Info 
CHEMBL4069075
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C22H25N5O5
  1
1
EC50 = 8000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0519456
 Compound Info 
5-[1-(6-bromopyridine-3-carbonyl)piperidin-4-yl]-3-(4-fluorophenyl)-2-methyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
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C24H21BrFN5O2
  1
1
EC50 = 12300 nM
 Bioactivity Info 
   TI
   LI
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CP0460485
 Compound Info 
3-(4-fluorophenyl)-2-methyl-5-(1-propanoylpiperidin-4-yl)-1H-pyrazolo[1,5-a]pyrimidin-7-one
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C21H23FN4O2
  1
1
EC50 = 28800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS