General Information of the Compound
Compound ID
CP0564251
Compound Name
CHEMBL4069075
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Formula
C22H25N5O5
Molecular Weight
439.472
Canonical SMILES
CCOC(=O)N1CCC(C)(CC1)c1cc(O)n2nc(C)c(-c3ccc(cc3)[N+]([O-])=O)c2n1
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InChI
InChI=1S/C22H25N5O5/c1-4-32-21(29)25-11-9-22(3,10-12-25)17-13-18(28)26-20(23-17)19(14(2)24-26)15-5-7-16(8-6-15)27(30)31/h5-8,13,28H,4,9-12H2,1-3H3
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InChIKey
ZZVNIQCKODXPKO-UHFFFAOYSA-N
Physicochemical Property
logP
3.82852
Rotatable Bonds
4
Heavy Atom Count
32
Polar Areas
123.1
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
8
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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ChEMBL ID
CHEMBL4069075
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06402, Short transient receptor potential channel 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 8000 nM
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