Brief Information of the Compound and Protein
Compound Name
ethyl 4-[3-(4-fluorophenyl)-2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carboxylate
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Canonical SMILES
CCOC(=O)N1CCC(CC1)c1cc(O)n2nc(C)c(-c3ccc(F)cc3)c2n1
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Compound Formula C21H23FN4O3
Compound Structure
Protein Name
Short transient receptor potential channel 6
Protein Classification
Ion channel
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Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
Q61143
Gene Name
TRPC6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  4
1
EC50 = 1400 nM
   TI
   LI
   LO
   TS
2
EC50 = 2500 nM
   TI
   LI
   LO
   TS
3
EC50 = 4660 nM
   TI
   LI
   LO
   TS
4
EC50 = 7200 nM
   TI
   LI
   LO
   TS