| Compound ID |
Compound Name |
Compound Formula |
|
CP0477388
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-[4-(dimethylamino)phenyl]acetamide
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|
C20H20F2N4O
|
1
|
| 1 |
IC50 = 3.4 nM
|
|
|
|
CP0408590
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-(1,3,3-trimethyl-2-oxoindol-5-yl)acetamide
Show/Hide
|
C23H22F2N4O2
|
1
|
| 1 |
IC50 = 3.8 nM
|
|
|
|
CP0412187
|
N-[1-[(4-chlorophenyl)methyl]pyrazol-3-yl]-2-[4-(dimethylamino)phenyl]acetamide
Show/Hide
|
C20H21ClN4O
|
1
|
| 1 |
IC50 = 4.1 nM
|
|
|
|
CP0412191
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-[4-(3-methyloxetan-3-yl)phenyl]acetamide
Show/Hide
|
C22H21F2N3O2
|
1
|
| 1 |
IC50 = 4.3 nM
|
|
|
|
CP0396378
|
2-[4-(dimethylamino)phenyl]-N-[1-[[4-(trifluoromethoxy)phenyl]methyl]pyrazol-3-yl]acetamide
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|
C21H21F3N4O2
|
1
|
| 1 |
IC50 = 5.1 nM
|
|
|
|
CP0389186
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-(1H-indol-6-yl)acetamide
Show/Hide
|
C20H16F2N4O
|
1
|
| 1 |
IC50 = 5.3 nM
|
|
|
|
CP0446022
|
(3R,5S)-N,1-dibenzyl-8-fluoro-3,5-dimethyl-3,5-dihydro-2H-pyrido[2,3-e][1,4]diazepine-4-carboxamide
Show/Hide
|
C25H27FN4O
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0412180
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-(4-propan-2-ylphenyl)acetamide
Show/Hide
|
C21H21F2N3O
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0520044
|
2-[4-(3,3-difluorocyclobutyl)phenyl]-N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]acetamide
Show/Hide
|
C22H19F4N3O
|
1
|
| 1 |
IC50 = 6.1 nM
|
|
|
|
CP0085972
|
3-chloro-2,5,5-trimethyl-N-[[2-(propan-2-yloxymethyl)phenyl]methyl]-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
|
C23H31ClN2O2
|
1
|
| 1 |
IC50 = 6.6 nM
|
|
|
|
CP0412184
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-[6-(3,3-difluoropyrrolidin-1-yl)pyridin-3-yl]acetamide
Show/Hide
|
C21H19F4N5O
|
1
|
| 1 |
IC50 = 6.7 nM
|
|
|
|
CP0255833
|
N-[1-[(5-cyanopyridin-2-yl)methyl]pyrazol-3-yl]-2-[3-methyl-4-(2,2,2-trifluoroethoxy)phenyl]acetamide
Show/Hide
|
C21H18F3N5O2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0412178
|
2-(4-tert-butylphenyl)-N-[1-[(5-cyanopyridin-2-yl)methyl]pyrazol-3-yl]acetamide
Show/Hide
|
C22H23N5O
|
1
|
| 1 |
IC50 = 7.5 nM
|
|
|
|
CP0396376
|
N-[1-[(3,5-difluoro-4-methoxyphenyl)methyl]pyrazol-3-yl]-2-[4-(dimethylamino)phenyl]acetamide
Show/Hide
|
C21H22F2N4O2
|
1
|
| 1 |
IC50 = 7.8 nM
|
|
|
|
CP0541307
|
N-[1-[(5-cyanopyridin-2-yl)methyl]pyrazol-3-yl]-2-[3-ethyl-4-(2,2,2-trifluoroethoxy)phenyl]acetamide
Show/Hide
|
C22H20F3N5O2
|
1
|
| 1 |
IC50 = 7.8 nM
|
|
|
|
CP0143412
|
2-(4-propan-2-ylphenyl)-N-[(1R)-1-[5-(2,2,2-trifluoroethoxy)pyridin-2-yl]ethyl]acetamide
Show/Hide
|
C20H23F3N2O2
|
1
|
| 1 |
IC50 = 8.2 nM
|
|
|
|
CP0481948
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-(1-methylindazol-5-yl)acetamide
Show/Hide
|
C20H17F2N5O
|
1
|
| 1 |
IC50 = 8.4 nM
|
|
|
|
CP0408536
|
N-[2-(3,4-Difluoro-benzyl)-2H-[1,2,3]triazol-4-yl]-2-(1-methyl-1H-indazol-5-yl)-acetamide
Show/Hide
|
C19H16F2N6O
|
1
|
| 1 |
IC50 = 8.6 nM
|
|
|
|
CP0382618
|
(3R,5S)-N-benzyl-1-[(2,3-difluorophenyl)methyl]-3,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C26H27F2N3O
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0392102
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-[4-(2,2-dimethyl-1,3-dioxolan-4-yl)phenyl]acetamide
Show/Hide
|
C23H23F2N3O3
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0412186
|
N-[1-[[4-(difluoromethoxy)phenyl]methyl]pyrazol-3-yl]-2-[4-(dimethylamino)phenyl]acetamide
Show/Hide
|
C21H22F2N4O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0477385
|
2-[4-(dimethylamino)phenyl]-N-[1-[(4-methylphenyl)methyl]pyrazol-3-yl]acetamide
Show/Hide
|
C21H24N4O
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0382629
|
(3R,5S)-1-[(2-fluorophenyl)methyl]-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C24H25FN4O
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0471804
|
2-[4-(3,3-difluorocyclobutyl)oxyphenyl]-N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]acetamide
Show/Hide
|
C22H19F4N3O2
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0424410
|
(3R,5S)-1-benzyl-8-fluoro-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C24H25FN4O
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0536135
|
3-chloro-2,5,5-trimethyl-N-[[2-(pyrazol-1-ylmethyl)phenyl]methyl]-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
|
C23H27ClN4O
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0412179
|
2-[4-(dimethylamino)phenyl]-N-[1-[(4-fluorophenyl)methyl]pyrazol-3-yl]acetamide
Show/Hide
|
C20H21FN4O
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0377009
|
(3R,5S)-N-benzyl-3,5-dimethyl-1-[[5-(trifluoromethyl)furan-2-yl]methyl]-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C25H26F3N3O2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0481954
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-[4-(3-fluorooxetan-3-yl)phenyl]acetamide
Show/Hide
|
C21H18F3N3O2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0396285
|
(3R,5S)-1-[(3-fluorophenyl)methyl]-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C24H25FN4O
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0452703
|
(3R,5S)-3,5-dimethyl-N-pyridin-3-yl-1-[[5-(trifluoromethyl)furan-2-yl]methyl]-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C23H23F3N4O2
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0477602
|
(3R,5S)-1-benzyl-N-[(4-methoxyphenyl)methyl]-3,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C27H31N3O2
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0404249
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-(1H-indol-5-yl)acetamide
Show/Hide
|
C20H16F2N4O
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0412200
|
N-[1-[(4-cyano-3-fluorophenyl)methyl]pyrazol-3-yl]-2-[4-(dimethylamino)phenyl]acetamide
Show/Hide
|
C21H20FN5O
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0551482
|
(3R,5S)-N-benzyl-3,5-dimethyl-1-[[2-(trifluoromethyl)-1,3-thiazol-5-yl]methyl]-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C24H25F3N4OS
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0446098
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-(3-methyl-2-oxo-1,3-benzoxazol-6-yl)acetamide
Show/Hide
|
C20H16F2N4O3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0554828
|
5-(4-bromophenyl)-N,3-bis(4-fluorophenyl)-3,4-dihydropyrazole-2-carboxamide
Show/Hide
|
C22H16BrF2N3O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0519622
|
(3R,5S)-1-[(3,4-difluorophenyl)methyl]-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C24H24F2N4O
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0085643
|
Act-709478
Show/Hide
|
C22H18F3N5O
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0227177
|
N-[1-[(5-cyanopyridin-2-yl)methyl]pyrazol-3-yl]-2-[3-methyl-4-(3,3,3-trifluoropropoxy)phenyl]acetamide
Show/Hide
|
C22H20F3N5O2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0475586
|
(5S,6S)-3-chloro-2,5,6-trimethyl-N-[[2-(2-methylpropoxy)phenyl]methyl]-4,5,6,7-tetrahydroisoindole-1-carboxamide
Show/Hide
|
C23H31ClN2O2
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0396345
|
N-[1-[(4-cyanophenyl)methyl]pyrazol-3-yl]-2-[4-(dimethylamino)phenyl]acetamide
Show/Hide
|
C21H21N5O
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0459417
|
(3S)-N,3-bis(4-fluorophenyl)-5-pyridin-4-yl-3,4-dihydropyrazole-2-carboxamide
Show/Hide
|
C21H16F2N4O
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0396309
|
3-chloro-N-[[2-(ethoxymethyl)phenyl]methyl]-2,5,5-trimethyl-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
|
C22H29ClN2O2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0471736
|
3-chloro-N-[(2-ethoxyphenyl)methyl]-2,5,5-trimethyl-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
|
C21H27ClN2O2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0471781
|
3-chloro-2-methyl-N-[[2-(2-methylpropoxy)phenyl]methyl]-5-(trifluoromethyl)-4,5,6,7-tetrahydroisoindole-1-carboxamide
Show/Hide
|
C22H26ClF3N2O2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0475590
|
3-chloro-2,5,5-trimethyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
|
C21H24ClF3N2O2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0520052
|
5-chloro-4-ethyl-1,3-dimethyl-N-[[2-(2-methylpropoxy)phenyl]methyl]pyrrole-2-carboxamide
Show/Hide
|
C20H27ClN2O2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0412194
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-[6-[(3S)-3-fluoropyrrolidin-1-yl]pyridin-3-yl]acetamide
Show/Hide
|
C21H20F3N5O
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0865123
|
N-(4-Cyano-1-(3,4-difluorobenzyl)-1H-pyrazol-3-yl)-2-(1-methyl-1H-indazol-5-yl)acetamide
Show/Hide
|
C21H16F2N6O
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0382620
|
(3R,5S)-1-benzyl-6,8-difluoro-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C24H24F2N4O
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0471802
|
N-[4-[(3,4-difluorophenyl)methyl]-1,3-thiazol-2-yl]-2-(4-propan-2-ylphenyl)acetamide
Show/Hide
|
C21H20F2N2OS
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0429377
|
3-chloro-2,5,5-trimethyl-N-[[3-(2,2,2-trifluoroethoxy)pyridin-2-yl]methyl]-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
|
C20H23ClF3N3O2
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0481950
|
N-(1-benzylpyrazol-3-yl)-2-(4-propan-2-ylphenyl)acetamide
Show/Hide
|
C21H23N3O
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0455946
|
(3R,5S)-N-[(4-methoxyphenyl)methyl]-3,5-dimethyl-1-[[5-(trifluoromethyl)furan-2-yl]methyl]-3,5-dihydro-2H-pyrido[3,4-e][1,4]diazepine-4-carboxamide
Show/Hide
|
C25H27F3N4O3
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0469496
|
N,3-bis(4-fluorophenyl)-5-phenyl-3,4-dihydropyrazole-2-carboxamide
Show/Hide
|
C22H17F2N3O
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0455950
|
(3R,5S)-1-[dideuterio(phenyl)methyl]-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C24H26N4O
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0470835
|
3-chloro-2,5,5-trimethyl-N-[[5-methyl-4-(pyrazol-1-ylmethyl)-1,2-oxazol-3-yl]methyl]-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
|
C21H26ClN5O2
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0475588
|
3-bromo-N-[[2-(methoxymethyl)phenyl]methyl]-5,5-dimethyl-6,7-dihydro-4H-2-benzothiophene-1-carboxamide
Show/Hide
|
C20H24BrNO2S
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0366788
|
N-[1-[(5-cyanopyridin-2-yl)methyl]pyrazol-3-yl]-2-[3-methyl-4-(trifluoromethoxy)phenyl]acetamide
Show/Hide
|
C20H16F3N5O2
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0450852
|
5-chloro-3-ethyl-1,4-dimethyl-N-[[2-(2-methylpropoxy)phenyl]methyl]pyrrole-2-carboxamide
Show/Hide
|
C20H27ClN2O2
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0475587
|
3-chloro-2-methyl-N-[[2-(2-methylpropoxy)phenyl]methyl]-5,6-dihydro-4H-cyclopenta[c]pyrrole-1-carboxamide
Show/Hide
|
C20H25ClN2O2
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0396291
|
(3R,5S)-N,1-dibenzyl-3,5,8-trimethyl-3,5-dihydro-2H-pyrido[2,3-e][1,4]diazepine-4-carboxamide
Show/Hide
|
C26H30N4O
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0444157
|
1-[(3R,5S)-3,5-dimethyl-1-[[2-(trifluoromethyl)-1,3-thiazol-5-yl]methyl]-3,5-dihydro-2H-1,4-benzodiazepin-4-yl]-3-pyridin-3-ylpropan-1-one
Show/Hide
|
C24H25F3N4OS
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0408544
|
1-[(3,4-difluorophenyl)methyl]-N-[[6-(3,3-difluoropyrrolidin-1-yl)pyridin-3-yl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C21H19F4N5O
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0412188
|
N-[(6-pyrrolidin-1-ylpyridin-3-yl)methyl]-2-[[4-(trifluoromethoxy)phenyl]methyl]-1,3-oxazole-4-carboxamide
Show/Hide
|
C22H21F3N4O3
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0377011
|
(3R,5S)-N,1-dibenzyl-3,5-dimethyl-3,5-dihydro-2H-pyrido[2,3-e][1,4]diazepine-4-carboxamide
Show/Hide
|
C25H28N4O
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0382630
|
(3R,5S)-1-[(4-fluorophenyl)methyl]-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C24H25FN4O
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0471801
|
2-(4-tert-butylphenyl)-N-[1-[(3,4-difluorophenyl)methyl]-1,2,4-triazol-3-yl]acetamide
Show/Hide
|
C21H22F2N4O
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0396377
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-[4-(oxetan-3-yloxy)phenyl]acetamide
Show/Hide
|
C21H19F2N3O3
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0059960
|
N,3-bis(4-fluorophenyl)-5-pyridin-4-yl-3,4-dihydropyrazole-2-carboxamide
Show/Hide
|
C21H16F2N4O
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0399520
|
(5R)-N-(4-bromophenyl)-5-(2-hydroxyethyl)-5-(4-methoxyphenyl)-3-pyridin-3-yl-4H-pyrazole-1-carboxamide
Show/Hide
|
C24H23BrN4O3
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0396294
|
(3R,5S)-N-benzyl-1-[(6-methoxypyridin-3-yl)methyl]-3,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C26H30N4O2
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0471733
|
3-cyano-2,5,5-trimethyl-N-[[3-(2,2,2-trifluoroethoxy)pyridin-2-yl]methyl]-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
|
C21H23F3N4O2
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0404251
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-[4-[(3-methyloxetan-3-yl)methoxy]phenyl]acetamide
Show/Hide
|
C23H23F2N3O3
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0541429
|
(2S,3S)-2-(1-(4-chlorophenyl)-2-(3-fluorophenyl)-3-oxo-2,7-diazaspiro[3.5]nonane-7-carboxamido)-3-methylpentanoic cyanic anhydride
Show/Hide
|
C27H28ClFN4O4
|
2
|
| 1 |
IC50 = 35 nM
|
|
|
| 2 |
IC50 = 17000 nM
|
|
|
|
CP0412468
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-(1-methylpyrrolo[2,3-b]pyridin-5-yl)acetamide
Show/Hide
|
C20H17F2N5O
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0377005
|
(3R,5S)-N,1-dibenzyl-8-chloro-3,5-dimethyl-3,5-dihydro-2H-pyrido[2,3-e][1,4]diazepine-4-carboxamide
Show/Hide
|
C25H27ClN4O
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0446099
|
2-[4-(dimethylamino)phenyl]-N-[1-[(3-methylphenyl)methyl]pyrazol-3-yl]acetamide
Show/Hide
|
C21H24N4O
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0444161
|
1-[(3R,5S)-1-benzyl-3,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepin-4-yl]-3-pyridin-3-ylpropan-1-one
Show/Hide
|
C26H29N3O
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0471738
|
3-chloro-2,5,5-trimethyl-N-[[2-(1,2,4-triazol-1-ylmethyl)phenyl]methyl]-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
|
C22H26ClN5O
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0396344
|
N-(1-benzylpyrazol-3-yl)-2-[4-(dimethylamino)phenyl]acetamide
Show/Hide
|
C20H22N4O
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0470836
|
3-chloro-2,5,5-trimethyl-N-[[2-(2,2,2-trifluoroethoxy)pyridin-3-yl]methyl]-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
|
C20H23ClF3N3O2
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0475589
|
3-bromo-N-[[2-(ethoxymethyl)phenyl]methyl]-5,5-dimethyl-6,7-dihydro-4H-2-benzothiophene-1-carboxamide
Show/Hide
|
C21H26BrNO2S
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0459418
|
N-(4-fluorophenyl)-3-(4-methylsulfonylphenyl)-5-phenyl-3,4-dihydropyrazole-2-carboxamide
Show/Hide
|
C23H20FN3O3S
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0405694
|
2-(3-chloro-4-fluorophenyl)-N-(3,5-difluorophenyl)-1-(pyridin-2-yl)-2,7-diazaspiro[3.5]nonane-7-carboxamide
Show/Hide
|
C25H22ClF3N4O
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0467444
|
2-(3-chloro-4-fluorophenyl)-N-(3,5-difluorophenyl)-1-oxo-3-(pyridin-2-yl)-2,7-diazaspiro[3.5]nonane-7-carboxamide
Show/Hide
|
C25H20ClF3N4O2
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0396286
|
(3R,5S)-N-benzyl-3,5-dimethyl-1-[[6-(trifluoromethyl)pyridin-2-yl]methyl]-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C26H27F3N4O
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0396287
|
(3R,5S)-3,5-dimethyl-N-pyridin-3-yl-1-[[2-(trifluoromethyl)-1,3-thiazol-5-yl]methyl]-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C22H22F3N5OS
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0471731
|
3-chloro-2,5,5-trimethyl-N-[[2-(3,3,3-trifluoropropoxy)phenyl]methyl]-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
|
C22H26ClF3N2O2
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0511059
|
2-(3-chlorophenyl)-7-(5-fluoro-6-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-3-(pyridin-2-yl)-2,7-diazaspiro[3.5]nonan-1-one
Show/Hide
|
C26H20ClF4N5O
|
2
|
| 1 |
IC50 = 44 nM
|
|
|
| 2 |
IC50 = 63 nM
|
|
|
|
CP0444064
|
(3R,5S)-N-benzyl-3,5-dimethyl-1-[2-[(2-methylpropan-2-yl)oxy]ethyl]-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C25H35N3O2
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0532987
|
(3R,5S)-N-benzyl-3,5-dimethyl-1-[[5-(trifluoromethyl)furan-2-yl]methyl]-3,5-dihydro-2H-pyrido[3,4-e][1,4]diazepine-4-carboxamide
Show/Hide
|
C24H25F3N4O2
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0481946
|
2-[4-(dimethylamino)phenyl]-N-[1-[(4-fluorophenyl)methyl]pyrazol-3-yl]propanamide
Show/Hide
|
C21H23FN4O
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0382829
|
(2S,3S)-isopropyl 2-(1-(4-chlorophenyl)-2-(3-fluorophenyl)-3-oxo-2,7-diazaspiro[3.5]nonane-7-carboxamido)-3-methylpentanoate
Show/Hide
|
C29H35ClFN3O4
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0459413
|
5-(4-bromophenyl)-N-(3-fluorophenyl)-3-(4-fluorophenyl)-3,4-dihydropyrazole-2-carboxamide
Show/Hide
|
C22H16BrF2N3O
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0412195
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-[6-(dimethylamino)pyridin-3-yl]acetamide
Show/Hide
|
C19H19F2N5O
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0446069
|
[(3R,5S)-1-benzyl-3,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepin-4-yl]-(oxan-4-yl)methanone
Show/Hide
|
C24H30N2O2
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0865213
|
2-(4-Dimethylamino-phenyl)-N-[1-(4-methoxy-benzyl)-1H-pyrazol-3-yl]-acetamide
Show/Hide
|
C21H24N4O2
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0444065
|
(3R,5S)-1-benzyl-N-[(4-methoxyphenyl)methyl]-3,5-dimethyl-3,5-dihydro-2H-pyrido[3,4-e][1,4]diazepine-4-carboxamide
Show/Hide
|
C26H30N4O2
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0382579
|
(3R,5S)-N-benzyl-1-[(2-fluoropyridin-3-yl)methyl]-3,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C25H27FN4O
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0532988
|
1-[(3R,5S)-1-benzyl-3,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepin-4-yl]-2-morpholin-4-ylethanone
Show/Hide
|
C24H31N3O2
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0408322
|
1-[(3R,5S)-1-benzyl-6-fluoro-3,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepin-4-yl]-3-pyridin-3-ylpropan-1-one
Show/Hide
|
C26H28FN3O
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0444018
|
(3R,5S)-1-benzyl-6-fluoro-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C24H25FN4O
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0408272
|
(5R)-N-(4-chlorophenyl)-5-(2-hydroxyethyl)-3-(4-methoxyphenyl)-5-pyridin-3-yl-4H-pyrazole-1-carboxamide
Show/Hide
|
C24H23ClN4O3
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
|
CP0377007
|
(3R,5S)-N-[(4-methoxyphenyl)methyl]-3,5-dimethyl-1-(3-methylbutyl)-3,5-dihydro-2H-pyrido[3,4-e][1,4]diazepine-4-carboxamide
Show/Hide
|
C24H34N4O2
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
|
CP0519621
|
1-[(3R,5S)-1-benzyl-3,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepin-4-yl]-2-(1,3-thiazol-5-yl)ethanone
Show/Hide
|
C23H25N3OS
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
|
CP0482595
|
3-chloro-2,6,6-trimethyl-N-[[2-(2-methylpropoxy)phenyl]methyl]-5,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
|
C23H31ClN2O2
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
|
CP0455786
|
3-chloro-N-[[3-[(3S)-3-fluoropyrrolidin-1-yl]pyridin-2-yl]methyl]-2,5,5-trimethyl-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
|
C22H28ClFN4O
|
1
|
| 1 |
IC50 = 56 nM
|
|
|
|
CP0481945
|
N-(1-benzylpyrazol-3-yl)-2-(4-methoxy-3-methylphenyl)acetamide
Show/Hide
|
C20H21N3O2
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
|
CP0377008
|
[(3R,5S)-1-benzyl-3,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepin-4-yl]-morpholin-4-ylmethanone
Show/Hide
|
C23H29N3O2
|
1
|
| 1 |
IC50 = 58 nM
|
|
|
|
CP0452712
|
(3R,5S)-1-benzyl-6-fluoro-3,5-dimethyl-N-(oxetan-3-yl)-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C22H26FN3O2
|
1
|
| 1 |
IC50 = 59 nM
|
|
|
|
CP0491072
|
2-(3-chloro-4-fluorophenyl)-7-(6-chloro-5-fluoro-1H-benzo[d]imidazol-2-yl)-3-(pyridin-2-yl)-2,7-diazaspiro[3.5]nonan-1-one
Show/Hide
|
C25H19Cl2F2N5O
|
2
|
| 1 |
IC50 = 60 nM
|
|
|
| 2 |
IC50 = 84 nM
|
|
|
|
CP0554826
|
N-(4-fluorophenyl)-5-(2-hydroxyethyl)-5-[4-(2-methoxyethoxy)phenyl]-3-phenyl-4H-pyrazole-1-carboxamide
Show/Hide
|
C27H28FN3O4
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0452701
|
(3R,5S)-1-benzyl-3,5-dimethyl-N-(oxetan-3-yl)-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C22H27N3O2
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0455947
|
(3R,5S)-1-benzyl-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C24H26N4O
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0486197
|
(2R,4S)-3,3,9-trimethyl-N-[[2-(trifluoromethyl)phenyl]methyl]-8-thiatricyclo[4.3.0.02,4]nona-1(9),6-diene-7-carboxamide
Show/Hide
|
C20H20F3NOS
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0382631
|
(3R,5S)-1-(cyclopentylmethyl)-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C23H30N4O
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0396289
|
1-[(3R,5S)-3,5-dimethyl-1-(3-methylbutyl)-3,5-dihydro-2H-1,4-benzodiazepin-4-yl]-3-pyridin-3-ylpropan-1-one
Show/Hide
|
C24H33N3O
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0494493
|
2-(4-propan-2-ylphenyl)-N-[1-[2-(2,2,2-trifluoroethoxy)ethyl]pyrazol-3-yl]acetamide
Show/Hide
|
C18H22F3N3O2
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0450850
|
3-bromo-N-[(2-ethoxyphenyl)methyl]-5,5-dimethyl-6,7-dihydro-4H-2-benzothiophene-1-carboxamide
Show/Hide
|
C20H24BrNO2S
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
|
CP0429373
|
3-cyano-2,5,5-trimethyl-N-[[2-(2,2,2-trifluoroethoxy)pyridin-3-yl]methyl]-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
|
C21H23F3N4O2
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0510168
|
1-[(3R,5S)-6-fluoro-3,5-dimethyl-1-(3-methylbutyl)-3,5-dihydro-2H-1,4-benzodiazepin-4-yl]-3-pyridin-3-ylpropan-1-one
Show/Hide
|
C24H32FN3O
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0376862
|
5-(4-bromophenyl)-3-(4-fluorophenyl)-N-phenyl-3,4-dihydropyrazole-2-carboxamide
Show/Hide
|
C22H17BrFN3O
|
1
|
| 1 |
IC50 = 68 nM
|
|
|
|
CP0444069
|
(3R,5S)-N,1-dibenzyl-7-chloro-3,5-dimethyl-3,5-dihydro-2H-pyrido[2,3-e][1,4]diazepine-4-carboxamide
Show/Hide
|
C25H27ClN4O
|
1
|
| 1 |
IC50 = 68 nM
|
|
|
|
CP0399518
|
N,5-bis(4-fluorophenyl)-5-(hydroxymethyl)-3-phenyl-4H-pyrazole-1-carboxamide
Show/Hide
|
C23H19F2N3O2
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0400297
|
7-(6-chloro-1H-benzo[d]imidazol-2-yl)-2-(3-chloro-4-fluorophenyl)-3-(pyridin-2-yl)-2,7-diazaspiro[3.5]nonan-1-one
Show/Hide
|
C25H20Cl2FN5O
|
2
|
| 1 |
IC50 = 71 nM
|
|
|
| 2 |
IC50 = 78 nM
|
|
|
|
CP0865116
|
4-(3,4-Difluorobenzyl)-N-(4-(dimethylamino)benzyl)thiazole-2-carboxamide
Show/Hide
|
C20H19F2N3OS
|
1
|
| 1 |
IC50 = 71 nM
|
|
|
|
CP0382624
|
(3R,5S)-N-benzyl-1-[(2,3-difluorophenyl)methyl]-3,5-dimethyl-3,5-dihydro-2H-pyrido[3,4-e][1,4]diazepine-4-carboxamide
Show/Hide
|
C25H26F2N4O
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0444047
|
(3R,5S)-N,1-dibenzyl-6-fluoro-3,5-dimethyl-3,5-dihydro-2H-pyrido[3,4-e][1,4]diazepine-4-carboxamide
Show/Hide
|
C25H27FN4O
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0410031
|
N-[[1-[2-(tert-butylamino)-2-oxoethyl]piperidin-4-yl]methyl]-3-chloro-5-fluorobenzamide
Show/Hide
|
C19H27ClFN3O2
|
1
|
| 1 |
IC50 = 73 nM
|
|
|
|
CP0412189
|
1-[(3,4-difluorophenyl)methyl]-N-[(4-propan-2-ylphenyl)methyl]pyrazole-3-carboxamide
Show/Hide
|
C21H21F2N3O
|
1
|
| 1 |
IC50 = 74 nM
|
|
|
|
CP0404137
|
[(1S,2R,4S)-2-[2-[3-(1H-benzimidazol-2-yl)propyl-methylamino]ethyl]-6-fluoro-4-hydroxy-1-propan-2-yl-3,4-dihydro-1H-naphthalen-2-yl] 2-methylpropanoate
Show/Hide
|
C30H40FN3O3
|
1
|
| 1 |
IC50 = 76 nM
|
|
|
|
CP0421965
|
1-(4-chlorophenyl)-2-(3-fluorophenyl)-N-((S)-1-(4-fluorophenyl)ethyl)-3-oxo-2,7-diazaspiro[3.5]nonane-7-carboxamide
Show/Hide
|
C28H26ClF2N3O2
|
1
|
| 1 |
IC50 = 82 nM
|
|
|
|
CP0463071
|
[(1R,8R,12R)-12-[2-[3-(4-methoxy-1H-benzimidazol-2-yl)propyl-methylamino]ethyl]-12-tricyclo[6.3.2.02,7]trideca-2,4,6-trienyl] 2-methylpropanoate
Show/Hide
|
C31H41N3O3
|
1
|
| 1 |
IC50 = 84 nM
|
|
|
|
CP0482176
|
2-[(3,4-difluorophenyl)methyl]-N-[(1-methylindazol-5-yl)methyl]triazole-4-carboxamide
Show/Hide
|
C19H16F2N6O
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0396296
|
(3R,5S)-3,5-dimethyl-1-[2-[(2-methylpropan-2-yl)oxy]ethyl]-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C23H32N4O2
|
1
|
| 1 |
IC50 = 91 nM
|
|
|
|
CP0444013
|
(3R,5S)-3,5-dimethyl-1-(3-methylbutyl)-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C22H30N4O
|
1
|
| 1 |
IC50 = 91 nM
|
|
|
|
CP0542970
|
1-[(3R,5S)-6-fluoro-3,5-dimethyl-1-[[2-(trifluoromethyl)-1,3-thiazol-5-yl]methyl]-3,5-dihydro-2H-1,4-benzodiazepin-4-yl]-3-pyridin-3-ylpropan-1-one
Show/Hide
|
C24H24F4N4OS
|
1
|
| 1 |
IC50 = 93 nM
|
|
|
|
CP0377006
|
(3R,5S)-N,1-dibenzyl-7-fluoro-3,5-dimethyl-3,5-dihydro-2H-pyrido[2,3-e][1,4]diazepine-4-carboxamide
Show/Hide
|
C25H27FN4O
|
1
|
| 1 |
IC50 = 95 nM
|
|
|
|
CP0452705
|
(3R,5S)-N-benzyl-1-[(2-fluorophenyl)methyl]-3,5-dimethyl-3,5-dihydro-2H-pyrido[3,4-e][1,4]diazepine-4-carboxamide
Show/Hide
|
C25H27FN4O
|
1
|
| 1 |
IC50 = 95 nM
|
|
|
|
CP0412183
|
1-[(3,4-difluorophenyl)methyl]-N-[[4-(3-fluorooxetan-3-yl)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C21H18F3N3O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0521801
|
2-[(3,4-difluorophenyl)methyl]-N-[[4-(dimethylamino)phenyl]methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C20H19F2N3OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0396292
|
(3R,5S)-N,1-dibenzyl-3,5-dimethyl-8-(trifluoromethyl)-3,5-dihydro-2H-pyrido[2,3-e][1,4]diazepine-4-carboxamide
Show/Hide
|
C26H27F3N4O
|
1
|
| 1 |
IC50 = 104 nM
|
|
|
|
CP0421967
|
2-(3-chloro-4-fluorophenyl)-7-(5-fluoro-6-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-3-(pyridin-2-yl)-2,7-diazaspiro[3.5]nonan-1-one
Show/Hide
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C26H19ClF5N5O
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1
|
| 1 |
IC50 = 106 nM
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CP0404138
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[(1S,2R,4R)-2-[2-[3-(1H-benzimidazol-2-yl)propyl-methylamino]ethyl]-6-fluoro-4-hydroxy-1-propan-2-yl-3,4-dihydro-1H-naphthalen-2-yl] 2-methylpropanoate
Show/Hide
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C30H40FN3O3
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1
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| 1 |
IC50 = 107 nM
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CP0405693
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(2S,3S)-methyl 2-(1-(4-chlorophenyl)-2-(3-fluorophenyl)-3-oxo-2,7-diazaspiro[3.5]nonane-7-carboxamido)-3-methylpentanoate
Show/Hide
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C27H31ClFN3O4
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1
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| 1 |
IC50 = 109 nM
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CP0546236
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benzyl N-[2-[3-[benzyl-(3-chlorophenyl)sulfamoyl]anilino]-2-oxoethyl]-N-methylcarbamate
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C30H28ClN3O5S
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1
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| 1 |
IC50 = 110 nM
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CP0382465
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N,3-bis(4-fluorophenyl)-5-(1-oxidopyridin-1-ium-4-yl)-3,4-dihydropyrazole-2-carboxamide
Show/Hide
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C21H16F2N4O2
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1
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| 1 |
IC50 = 110 nM
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CP0475591
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3-chloro-2,5,5-trimethyl-N-[[3-(2,2,2-trifluoroethoxy)pyridin-4-yl]methyl]-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
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C20H23ClF3N3O2
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1
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| 1 |
IC50 = 110 nM
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CP0534565
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2,5,5-trimethyl-N-[[2-(2,2,2-trifluoroethoxy)pyridin-3-yl]methyl]-3-(trifluoromethyl)-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
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C21H23F6N3O2
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1
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| 1 |
IC50 = 110 nM
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CP0444045
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(3R,5S)-1-benzyl-7-fluoro-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
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C24H25FN4O
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1
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| 1 |
IC50 = 112 nM
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CP0463072
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[(1S,2R,4S)-2-[2-[3-(1H-benzimidazol-2-yl)propyl-methylamino]ethyl]-6-fluoro-4-phenylmethoxy-1-propan-2-yl-3,4-dihydro-1H-naphthalen-2-yl] 2-methylpropanoate
Show/Hide
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C37H46FN3O3
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1
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| 1 |
IC50 = 113 nM
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CP0491071
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2-(3-chlorophenyl)-N-(3,4-difluorophenyl)-1-oxo-3-(pyridin-2-yl)-2,7-diazaspiro[3.5]nonane-7-carboxamide
Show/Hide
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C25H21ClF2N4O2
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1
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| 1 |
IC50 = 118 nM
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CP0376861
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N-(4-fluorophenyl)-5-(2-hydroxyethyl)-3,5-diphenyl-4H-pyrazole-1-carboxamide
Show/Hide
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C24H22FN3O2
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1
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| 1 |
IC50 = 120 nM
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CP0404250
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N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-(3-methylbenzimidazol-5-yl)acetamide
Show/Hide
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C20H17F2N5O
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1
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| 1 |
IC50 = 120 nM
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CP0013607
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2-methoxyacetic acid [(1S,2S)-2-[2-[3-(1H-benzimidazol-2-yl)propyl-methyl-amino]ethyl]-6-fluoro-1-isopropyl-tetralin-2-yl] ester;hydrate;hydrochloride
Show/Hide
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C29H38FN3O3
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3
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| 1 |
IC50 = 130 nM
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| 2 |
IC50 = 181 nM
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| 3 |
IC50 = 1000 nM
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CP0539423
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[(1S,2R,4R)-2-[2-[3-(1H-benzimidazol-2-yl)propyl-methylamino]ethyl]-6-fluoro-4-phenylmethoxy-1-propan-2-yl-3,4-dihydro-1H-naphthalen-2-yl] 2-methylpropanoate
Show/Hide
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C37H46FN3O3
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1
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| 1 |
IC50 = 132 nM
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CP0129660
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1-(4-chlorophenyl)-N-(3,5-difluorophenyl)-2-isopropyl-2,7-diazaspiro[3.5]nonane-7-carboxamide
Show/Hide
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C23H26ClF2N3O
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2
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| 1 |
IC50 = 138 nM
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| 2 |
IC50 = 328 nM
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CP0488772
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1-(4-chlorophenyl)-2-(3-fluorophenyl)-3-oxo-N-((S)-1-phenylethyl)-2,7-diazaspiro[3.5]nonane-7-carboxamide
Show/Hide
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C28H27ClFN3O2
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1
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| 1 |
IC50 = 139 nM
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CP0410029
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N-(4-bromophenyl)-5-(2-hydroxyethyl)-5-(4-methoxyphenyl)-3-pyridin-3-yl-4H-pyrazole-1-carboxamide
Show/Hide
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C24H23BrN4O3
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1
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| 1 |
IC50 = 140 nM
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CP0477386
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N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-[6-(2,2,2-trifluoroethoxy)pyridin-3-yl]acetamide
Show/Hide
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C19H15F5N4O2
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1
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| 1 |
IC50 = 140 nM
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CP0568717
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N-[1-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]ethyl]-2-(4-propan-2-ylphenyl)acetamide
Show/Hide
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C23H25F2N3O
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1
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| 1 |
IC50 = 140 nM
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CP0382615
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(3R)-N,1-dibenzyl-3-methyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
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C25H27N3O
|
1
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| 1 |
IC50 = 141 nM
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CP0573758
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[(1S,2S)-2-[2-[3-(1H-benzimidazol-2-yl)propyl-methylamino]ethyl]-6-fluoro-1-propan-2-yl-3,4-dihydro-1H-naphthalen-2-yl] 2-methylpropanoate
Show/Hide
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C30H40FN3O2
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1
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| 1 |
IC50 = 149 nM
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CP0429720
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N-(1-benzylpyrazol-3-yl)-2-[4-(trifluoromethoxy)phenyl]acetamide
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C19H16F3N3O2
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1
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| 1 |
IC50 = 155 nM
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CP0475592
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(2R,4S)-N-[[4-(ethoxymethyl)phenyl]methyl]-3,3,9-trimethyl-8-thiatricyclo[4.3.0.02,4]nona-1(9),6-diene-7-carboxamide
Show/Hide
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C22H27NO2S
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1
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| 1 |
IC50 = 160 nM
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CP0412463
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N-[[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]methyl]-2-(4-propan-2-ylphenyl)acetamide
Show/Hide
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C22H23F2N3O
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1
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| 1 |
IC50 = 160 nM
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CP0486049
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4-[[2-[(4-fluorophenyl)methyl]-4H-imidazo[4,5-c]pyrazol-5-yl]methyl]-N,N-dimethylaniline
Show/Hide
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C20H20FN5
|
1
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| 1 |
IC50 = 160 nM
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CP0396361
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1-benzyl-4-(difluoromethyl)-5-phenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
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C27H22F5N3O2
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1
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| 1 |
IC50 = 170 nM
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CP0421961
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N-(3,5-difluorophenyl)-3-(4-fluorophenyl)-2-propan-2-yl-2,7-diazaspiro[3.5]nonane-7-carboxamide
Show/Hide
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C23H26F3N3O
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2
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| 1 |
IC50 = 172 nM
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| 2 |
IC50 = 995 nM
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CP0129662
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1-(4-chlorophenyl)-N-(3,4-difluorophenyl)-2-isopropyl-2,7-diazaspiro[3.5]nonane-7-carboxamide
Show/Hide
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C23H26ClF2N3O
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2
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| 1 |
IC50 = 174 nM
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| 2 |
IC50 = 340 nM
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CP0497490
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1-(4-chlorophenyl)-N-(3,5-difluorophenyl)-2-isobutyl-2,7-diazaspiro[3.5]nonane-7-carboxamide
Show/Hide
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C24H28ClF2N3O
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1
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| 1 |
IC50 = 177 nM
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CP0457159
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benzyl N-[2-[3-[(3-chlorophenyl)-(4-methylpentyl)sulfamoyl]anilino]-2-oxoethyl]-N-methylcarbamate
Show/Hide
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C29H34ClN3O5S
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1
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| 1 |
IC50 = 180 nM
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CP0471472
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1-(4-chlorophenyl)-2-(3-fluorophenyl)-N-((2S,3S)-3-methyl-1-(methylamino)-1-oxopentan-2-yl)-3-oxo-2,7-diazaspiro[3.5]nonane-7-carboxamide
Show/Hide
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C27H32ClFN4O3
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1
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| 1 |
IC50 = 182 nM
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CP0425133
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[(1R,8R,12R)-12-[2-[3-(1H-benzimidazol-2-yl)propyl-methylamino]ethyl]-12-tricyclo[6.3.2.02,7]trideca-2,4,6-trienyl] 2-methylpropanoate
Show/Hide
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C30H39N3O2
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1
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| 1 |
IC50 = 184 nM
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CP0412202
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2-[4-(dimethylamino)phenyl]-N-[1-[(2-methylphenyl)methyl]pyrazol-3-yl]acetamide
Show/Hide
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C21H24N4O
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1
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| 1 |
IC50 = 190 nM
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CP0459982
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[(1S,2S,4R)-2-[2-[3-(1H-benzimidazol-2-yl)propyl-methylamino]ethyl]-4-butyl-6-fluoro-1-propan-2-yl-3,4-dihydro-1H-naphthalen-2-yl] 2-methoxyacetate
Show/Hide
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C33H46FN3O3
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1
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| 1 |
IC50 = 193 nM
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CP0396283
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(2R,5S)-N,1-dibenzyl-2,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
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C26H29N3O
|
1
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| 1 |
IC50 = 198 nM
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CP0380491
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3-(4-fluorophenyl)-5-phenyl-N-pyridin-4-yl-3,4-dihydropyrazole-2-carboxamide
Show/Hide
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C21H17FN4O
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1
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| 1 |
IC50 = 202 nM
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CP0396153
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(3R,5S)-1-benzyl-9-fluoro-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C24H25FN4O
|
1
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| 1 |
IC50 = 205 nM
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CP0425136
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[(1S,2S)-2-[2-[3-(1H-benzimidazol-2-yl)propyl-methylamino]ethyl]-6-fluoro-4,4-dimethyl-1-propan-2-yl-1,3-dihydronaphthalen-2-yl] 2-methoxyacetate
Show/Hide
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C31H42FN3O3
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1
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| 1 |
IC50 = 207 nM
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CP0396297
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(3R,5S)-N-benzyl-3,5-dimethyl-1-phenyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
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C25H27N3O
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1
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| 1 |
IC50 = 209 nM
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CP0425135
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[(1S,8S,9S)-9-[2-[3-(1H-benzimidazol-2-yl)propyl-methylamino]ethyl]-9-tricyclo[6.2.2.02,7]dodeca-2,4,6-trienyl] cyclopropanecarboxylate
Show/Hide
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C29H35N3O2
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1
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| 1 |
IC50 = 210 nM
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CP0412466
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N-(1-benzylpyrazol-3-yl)-2-(4-methylphenyl)acetamide
Show/Hide
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C19H19N3O
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1
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| 1 |
IC50 = 210 nM
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CP0486052
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N-(1-benzylpyrazol-3-yl)-2-(4-ethoxyphenyl)acetamide
Show/Hide
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C20H21N3O2
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1
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| 1 |
IC50 = 210 nM
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CP0382582
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(3R,5S)-N,1-dibenzyl-3,5-dimethyl-3,5-dihydro-2H-pyrido[3,2-e][1,4]diazepine-4-carboxamide
Show/Hide
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C25H28N4O
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1
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| 1 |
IC50 = 212 nM
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CP0502328
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1-(4-chlorophenyl)-N-(3,5-difluorophenyl)-2-methyl-2,7-diazaspiro[3.5]nonane-7-carboxamide
Show/Hide
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C21H22ClF2N3O
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1
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| 1 |
IC50 = 214 nM
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CP0408587
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4-bromo-1-methyl-5-phenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
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C20H17BrF3N3O2
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1
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| 1 |
IC50 = 220 nM
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CP0908753
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2-(6-Cyclopropyl-pyridin-3-yl)-N-[1-(3,4-difluoro-benzyl)-1H-pyrazol-3-yl]-acetamide
Show/Hide
|
C20H18F2N4O
|
1
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| 1 |
IC50 = 220 nM
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CP0501583
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1-(4-chlorophenyl)-2-(3-fluorophenyl)-3-oxo-N-((S)-1-phenylpropyl)-2,7-diazaspiro[3.5]nonane-7-carboxamide
Show/Hide
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C29H29ClFN3O2
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1
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| 1 |
IC50 = 224 nM
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CP0425128
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3-(1H-benzimidazol-2-yl)-N-[2-[(1S,8S,9S)-9-methoxy-9-tricyclo[6.2.2.02,7]dodeca-2,4,6-trienyl]ethyl]-N-methylpropan-1-amine
Show/Hide
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C26H33N3O
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1
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| 1 |
IC50 = 224 nM
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CP0452704
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(3R,5S)-N,1-dibenzyl-7-chloro-3,5-dimethyl-3,5-dihydro-2H-pyrido[3,4-e][1,4]diazepine-4-carboxamide
Show/Hide
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C25H27ClN4O
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1
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| 1 |
IC50 = 224 nM
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CP0395729
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1-[(3R,5S)-1-benzyl-3,5-dimethyl-3,5-dihydro-2H-pyrido[3,4-e][1,4]diazepin-4-yl]-3-(4-fluorophenyl)propan-1-one
Show/Hide
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C26H28FN3O
|
1
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| 1 |
IC50 = 225 nM
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CP0870883
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(+/-)-N-Benzyl-3,5-dimethyl-1-(phenylmethyl-d2)-1,2,3,5-tetrahydro-4H-pyrido[3,4-e][1,4]diazepine-4-carboxamide
Show/Hide
|
C25H28N4O
|
1
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| 1 |
IC50 = 230 nM
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CP0396298
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(3R,5S)-1-benzyl-3,5,8-trimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C25H28N4O
|
1
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| 1 |
IC50 = 231 nM
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CP0457160
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propan-2-yl 2-(3-chloro-N-[3-[[2-[methyl(phenylmethoxycarbonyl)amino]acetyl]amino]phenyl]sulfonylanilino)acetate
Show/Hide
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C28H30ClN3O7S
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1
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| 1 |
IC50 = 240 nM
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CP0399522
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5-[2-(dimethylamino)ethyl]-N-(4-fluorophenyl)-5-(4-methylphenyl)-3-phenyl-4H-pyrazole-1-carboxamide
Show/Hide
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C27H29FN4O
|
1
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| 1 |
IC50 = 240 nM
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CP0424412
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(3R,5S)-1-benzyl-6-fluoro-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-pyrido[3,4-e][1,4]diazepine-4-carboxamide
Show/Hide
|
C23H24FN5O
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1
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| 1 |
IC50 = 240 nM
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CP0389181
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3,5-dichloro-4-cyclopropyl-1-methyl-N-[[2-(2-methylpropoxy)phenyl]methyl]pyrrole-2-carboxamide
Show/Hide
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C20H24Cl2N2O2
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1
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| 1 |
IC50 = 240 nM
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CP0444160
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(5S)-N,1-dibenzyl-5-methyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C25H27N3O
|
1
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| 1 |
IC50 = 241 nM
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CP0388256
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(2S)-methyl 3-tert-butoxy-2-(1-(4-chlorophenyl)-2-(3-fluorophenyl)-3-oxo-2,7-diazaspiro[3.5]nonane-7-carboxamido)propanoate
Show/Hide
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C28H33ClFN3O5
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1
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| 1 |
IC50 = 251 nM
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CP0467443
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(2R,3R)-methyl 2-(1-(4-fluorophenyl)-2-isopropyl-2,7-diazaspiro[3.5]nonane-7-carboxamido)-3-methylpentanoate
Show/Hide
|
C24H36FN3O3
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1
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| 1 |
IC50 = 256 nM
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CP0481947
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3-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-5-[(4-propan-2-ylphenyl)methyl]-1H-1,2,4-triazole
Show/Hide
|
C22H21F2N5
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1
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| 1 |
IC50 = 260 nM
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CP0445134
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6-(3-ethylpent-2-enyl)-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
Show/Hide
|
C22H24O5
|
1
|
| 1 |
IC50 = 260 nM
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CP0213567
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4-[2-(ethylamino)ethyl]-1,5-diphenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C29H29F3N4O2
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1
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| 1 |
IC50 = 280 nM
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CP0486051
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N-(1-benzylpyrazol-3-yl)-2-(4-chlorophenyl)acetamide
Show/Hide
|
C18H16ClN3O
|
1
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| 1 |
IC50 = 280 nM
|
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CP0567831
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5-(4-bromophenyl)-N,3-bis(4-fluorophenyl)-3,4-dihydropyrazole-2-carbothioamide
Show/Hide
|
C22H16BrF2N3S
|
1
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| 1 |
IC50 = 281 nM
|
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CP0473607
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2-(3,4-difluorophenyl)-1-oxo-3-(pyridin-2-yl)-N-(3-(trifluoromethyl)phenyl)-2,7-diazaspiro[3.5]nonane-7-carboxamide
Show/Hide
|
C26H21F5N4O2
|
1
|
| 1 |
IC50 = 283 nM
|
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CP0429388
|
4-bromo-5-cyclopropyl-1-(2-fluorophenyl)-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C22H18BrF4N3O2
|
1
|
| 1 |
IC50 = 290 nM
|
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CP0282371
|
2-[4-[2-(tert-butylcarbamoylamino)ethyl]piperazin-1-yl]-N-(3,5-dichlorophenyl)acetamide
Show/Hide
|
C19H29Cl2N5O2
|
1
|
| 1 |
IC50 = 300 nM
|
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CP0408586
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4-bromo-1-(2-fluorophenyl)-5-phenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C25H18BrF4N3O2
|
1
|
| 1 |
IC50 = 300 nM
|
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CP0382580
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(3R,5S)-1-benzyl-6-methoxy-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C25H28N4O2
|
1
|
| 1 |
IC50 = 305 nM
|
|
|
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CP0396364
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4-(2-hydroxyethyl)-1,5-diphenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C27H24F3N3O3
|
1
|
| 1 |
IC50 = 310 nM
|
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|
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CP0549306
|
3,5-dichloro-N-[[3-(3,3-dimethylbutyl)-3-azabicyclo[3.1.0]hexan-6-yl]methyl]benzamide
Show/Hide
|
C19H26Cl2N2O
|
1
|
| 1 |
IC50 = 310 nM
|
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CP0382464
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5-(4-bromophenyl)-N-cyclohexyl-3-(4-fluorophenyl)-3,4-dihydropyrazole-2-carboxamide
Show/Hide
|
C22H23BrFN3O
|
1
|
| 1 |
IC50 = 316 nM
|
|
|
|
CP0428656
|
[(1S,2R,4S)-2-[2-[3-(1H-benzimidazol-2-yl)propyl-methylamino]ethyl]-6-fluoro-4-methoxy-1-propan-2-yl-3,4-dihydro-1H-naphthalen-2-yl] 2-methylpropanoate
Show/Hide
|
C31H42FN3O3
|
1
|
| 1 |
IC50 = 318 nM
|
|
|
|
CP0398337
|
(3R)-N,3-bis(4-fluorophenyl)-5-pyridin-4-yl-3,4-dihydropyrazole-2-carboxamide
Show/Hide
|
C21H16F2N4O
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
|
CP0535760
|
methyl (2S,3S)-2-[[3-(4-chlorophenyl)-2-cyclopropyl-2,7-diazaspiro[3.5]nonane-7-carbonyl]amino]-3-methylpentanoate
Show/Hide
|
C24H34ClN3O3
|
2
|
| 1 |
IC50 = 325 nM
|
|
|
| 2 |
IC50 = 713 nM
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|
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CP0566172
|
N-(4-fluorophenyl)-5-(2-hydroxyethyl)-5-(4-methylphenyl)-3-pyridin-4-yl-4H-pyrazole-1-carboxamide
Show/Hide
|
C24H23FN4O2
|
1
|
| 1 |
IC50 = 330 nM
|
|
|
|
CP0471732
|
2,5,5-trimethyl-N-[[2-(2,2,2-trifluoroethoxy)pyridin-3-yl]methyl]-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
|
C20H24F3N3O2
|
1
|
| 1 |
IC50 = 330 nM
|
|
|
|
CP0389209
|
1-[(3,4-difluorophenyl)methyl]-N-(1H-indol-5-ylmethyl)pyrazole-3-carboxamide
Show/Hide
|
C20H16F2N4O
|
1
|
| 1 |
IC50 = 330 nM
|
|
|
|
CP0396284
|
(3S,5S)-N,1-dibenzyl-3,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C26H29N3O
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0450851
|
3-bromo-5,5-dimethyl-N-[(2-propan-2-yloxyphenyl)methyl]-6,7-dihydro-4H-2-benzothiophene-1-carboxamide
Show/Hide
|
C21H26BrNO2S
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0399521
|
N-(4-fluorophenyl)-5-(methoxymethyl)-5-(4-methylphenyl)-3-phenyl-4H-pyrazole-1-carboxamide
Show/Hide
|
C25H24FN3O2
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0396362
|
4-bromo-1,5-diphenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C25H19BrF3N3O2
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0504693
|
1-(4-chlorophenyl)-2-(3-fluorophenyl)-3-oxo-N-((R)-1-phenylethyl)-2,7-diazaspiro[3.5]nonane-7-carboxamide
Show/Hide
|
C28H27ClFN3O2
|
1
|
| 1 |
IC50 = 351 nM
|
|
|
|
CP0396293
|
(3S,5R)-N,1-dibenzyl-3,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C26H29N3O
|
1
|
| 1 |
IC50 = 358 nM
|
|
|
|
CP0428655
|
[(1S,8S,9S)-9-[2-[3-(1H-benzimidazol-2-yl)propyl-methylamino]ethyl]-9-tricyclo[6.2.2.02,7]dodeca-2,4,6-trienyl] 2-methoxyacetate
Show/Hide
|
C28H35N3O3
|
1
|
| 1 |
IC50 = 361 nM
|
|
|
|
CP0429392
|
4-(difluoromethyl)-1-methyl-5-phenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C21H18F5N3O2
|
1
|
| 1 |
IC50 = 370 nM
|
|
|
|
CP0389183
|
tert-butyl 3-chloro-2-methyl-1-[[2-(2-methylpropoxy)phenyl]methylcarbamoyl]-4,6-dihydropyrrolo[3,4-c]pyrrole-5-carboxylate
Show/Hide
|
C24H32ClN3O4
|
1
|
| 1 |
IC50 = 370 nM
|
|
|
|
CP0536131
|
(2R,4S)-3,3,9-trimethyl-N-[[3-(trifluoromethoxy)phenyl]methyl]-8-thiatricyclo[4.3.0.02,4]nona-1(9),6-diene-7-carboxamide
Show/Hide
|
C20H20F3NO2S
|
1
|
| 1 |
IC50 = 370 nM
|
|
|
|
CP0408588
|
4-bromo-5-ethyl-1-phenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C21H19BrF3N3O2
|
1
|
| 1 |
IC50 = 380 nM
|
|
|
|
CP0476828
|
4-bromo-1,5-diphenyl-N-[[3-(2,2,2-trifluoroethoxy)pyridin-2-yl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C24H18BrF3N4O2
|
1
|
| 1 |
IC50 = 380 nM
|
|
|
|
CP0399517
|
5-(4-bromophenyl)-3-(4-fluorophenyl)-N-propan-2-yl-3,4-dihydropyrazole-2-carboxamide
Show/Hide
|
C19H19BrFN3O
|
1
|
| 1 |
IC50 = 382 nM
|
|
|
|
CP0539494
|
6-(3-ethylpent-2-enyl)-5,7-dihydroxy-2-(2-hydroxyphenyl)-2,3-dihydrochromen-4-one
Show/Hide
|
C22H24O5
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
|
CP0382626
|
N,1-dibenzyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C24H25N3O
|
1
|
| 1 |
IC50 = 392 nM
|
|
|
|
CP0567829
|
5-(4-bromophenyl)-3-(4-fluorophenyl)-N-pyridin-2-yl-3,4-dihydropyrazole-2-carboxamide
Show/Hide
|
C21H16BrFN4O
|
1
|
| 1 |
IC50 = 393 nM
|
|
|
|
CP0501930
|
1-(4-chlorophenyl)-2-cyclopropyl-N-(3,5-difluorophenyl)-2,7-diazaspiro[3.5]nonane-7-carboxamide
Show/Hide
|
C23H24ClF2N3O
|
1
|
| 1 |
IC50 = 398 nM
|
|
|
|
CP0553937
|
[(1R,8R,9R)-9-[2-[3-(1H-benzimidazol-2-yl)propyl-methylamino]ethyl]-9-tricyclo[6.2.2.02,7]dodeca-2,4,6-trienyl] 2-methylpropanoate
Show/Hide
|
C29H37N3O2
|
1
|
| 1 |
IC50 = 398 nM
|
|
|
|
CP0282366
|
N-[[1-[2-(tert-butylcarbamoylamino)ethyl]pyrrolidin-3-yl]methyl]-3,5-dichlorobenzamide
Show/Hide
|
C19H28Cl2N4O2
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0518118
|
4-bromo-1,5-diphenyl-N-[(2-pyrazol-1-ylphenyl)methyl]pyrazole-3-carboxamide
Show/Hide
|
C26H20BrN5O
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0388254
|
N-(3,5-difluorophenyl)-3-(4-fluorophenyl)-2-methyl-2,7-diazaspiro[3.5]nonane-7-carboxamide
Show/Hide
|
C21H22F3N3O
|
1
|
| 1 |
IC50 = 410 nM
|
|
|
|
CP0491069
|
(2S,3S)-methyl 2-(1-(4-chlorophenyl)-2-methyl-2,7-diazaspiro[3.5]nonane-7-carboxamido)-3-methylpentanoate
Show/Hide
|
C22H32ClN3O3
|
1
|
| 1 |
IC50 = 410 nM
|
|
|
|
CP0463866
|
N-(4-fluorophenyl)-3-methyl-5-phenyl-3,4-dihydropyrazole-2-carboxamide
Show/Hide
|
C17H16FN3O
|
1
|
| 1 |
IC50 = 410 nM
|
|
|
|
CP0520712
|
N-(4-fluorophenyl)-3-(4-methylsulfonylphenyl)-5-pyridin-4-yl-3,4-dihydropyrazole-2-carboxamide
Show/Hide
|
C22H19FN4O3S
|
1
|
| 1 |
IC50 = 410 nM
|
|
|
|
CP0408589
|
4-(hydroxymethyl)-1,5-diphenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C26H22F3N3O3
|
1
|
| 1 |
IC50 = 410 nM
|
|
|
|
CP0536149
|
4-bromo-1-(4-fluorophenyl)-5-phenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C25H18BrF4N3O2
|
1
|
| 1 |
IC50 = 410 nM
|
|
|
|
CP0382622
|
(3R,5S)-1-benzyl-8-fluoro-7-methoxy-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C25H27FN4O2
|
1
|
| 1 |
IC50 = 414 nM
|
|
|
|
CP0372728
|
propan-2-yl 2-(3-chloro-N-[3-[3-(phenylmethoxycarbonylamino)propanoylamino]phenyl]sulfonylanilino)acetate
Show/Hide
|
C28H30ClN3O7S
|
1
|
| 1 |
IC50 = 420 nM
|
|
|
|
CP0459416
|
5-(4-bromophenyl)-3-(4-fluorophenyl)-N-(2-phenylethyl)-3,4-dihydropyrazole-2-carboxamide
Show/Hide
|
C24H21BrFN3O
|
1
|
| 1 |
IC50 = 420 nM
|
|
|
|
CP0555467
|
N-(4-fluorophenyl)-5-(2-hydroxyethyl)-5-(4-methylsulfonylphenyl)-3-phenyl-4H-pyrazole-1-carboxamide
Show/Hide
|
C25H24FN3O4S
|
1
|
| 1 |
IC50 = 420 nM
|
|
|
|
CP0446025
|
(3R,5S)-1-benzyl-8-bromo-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C24H25BrN4O
|
1
|
| 1 |
IC50 = 428 nM
|
|
|
|
CP0459412
|
N-(4-fluorophenyl)-5-(4-methylphenyl)-5-(2-morpholin-4-ylethyl)-3-phenyl-4H-pyrazole-1-carboxamide
Show/Hide
|
C29H31FN4O2
|
1
|
| 1 |
IC50 = 430 nM
|
|
|
|
CP0398336
|
5-(4-bromophenyl)-3-(4-fluorophenyl)-N-(4-methoxyphenyl)-3,4-dihydropyrazole-2-carboxamide
Show/Hide
|
C23H19BrFN3O2
|
1
|
| 1 |
IC50 = 447 nM
|
|
|
|
CP0539493
|
6-(2-cyclopentylideneethyl)-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
Show/Hide
|
C22H22O5
|
1
|
| 1 |
IC50 = 460 nM
|
|
|
|
CP0382616
|
(2S,5S)-N,1-dibenzyl-2,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C26H29N3O
|
1
|
| 1 |
IC50 = 464 nM
|
|
|
|
CP0429371
|
3-bromo-N-[[4-(methoxymethyl)phenyl]methyl]-5,5-dimethyl-6,7-dihydro-4H-2-benzothiophene-1-carboxamide
Show/Hide
|
C20H24BrNO2S
|
1
|
| 1 |
IC50 = 470 nM
|
|
|
|
CP0446023
|
(3R,5S)-N-benzyl-3,5-dimethyl-1-(pyridin-2-ylmethyl)-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C25H28N4O
|
1
|
| 1 |
IC50 = 479 nM
|
|
|
|
CP0445135
|
5,7-dihydroxy-2-(4-hydroxyphenyl)-6-(3-methylbutyl)-2,3-dihydrochromen-4-one
Show/Hide
|
C20H22O5
|
1
|
| 1 |
IC50 = 480 nM
|
|
|
|
CP0282368
|
N-[[1-[2-(tert-butylcarbamoylamino)ethyl]piperidin-3-yl]methyl]-3,5-dichlorobenzamide
Show/Hide
|
C20H30Cl2N4O2
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0282370
|
N-[[1-[2-(tert-butylcarbamoylamino)ethyl]piperidin-4-yl]methyl]-3,5-dichlorobenzamide
Show/Hide
|
C20H30Cl2N4O2
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0296630
|
N-(1-adamantyl)-2-[4-[2-(tert-butylcarbamoylamino)ethyl]piperazin-1-yl]acetamide
Show/Hide
|
C23H41N5O2
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0334974
|
N-[1-[2-(tert-butylcarbamoylamino)ethyl]piperidin-3-yl]-3,5-dichlorobenzamide
Show/Hide
|
C19H28Cl2N4O2
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0455948
|
(3R,5S)-N-benzyl-3,5-dimethyl-1-(pyridin-3-ylmethyl)-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C25H28N4O
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0539492
|
6-(2-cyclopentylethyl)-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
Show/Hide
|
C22H24O5
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0482011
|
N-benzyl-1,5-diphenylpyrazole-3-carboxamide
Show/Hide
|
C23H19N3O
|
1
|
| 1 |
IC50 = 510 nM
|
|
|
|
CP0418472
|
2-(5-chloropyridin-3-yl)-N-(3,5-difluorophenyl)-1-oxo-3-(pyridin-2-yl)-2,7-diazaspiro[3.5]nonane-7-carboxamide
Show/Hide
|
C24H20ClF2N5O2
|
1
|
| 1 |
IC50 = 519 nM
|
|
|
|
CP0382581
|
(3R,5S)-1-benzyl-7-methoxy-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C25H28N4O2
|
1
|
| 1 |
IC50 = 530 nM
|
|
|
|
CP0471735
|
(2R,4S)-3,3,9-trimethyl-N-[[3-(trifluoromethyl)phenyl]methyl]-8-thiatricyclo[4.3.0.02,4]nona-1(9),6-diene-7-carboxamide
Show/Hide
|
C20H20F3NOS
|
1
|
| 1 |
IC50 = 530 nM
|
|
|
|
CP0457158
|
propan-2-yl 2-(3-chloro-N-[3-(3-phenylpropanoylamino)phenyl]sulfonylanilino)acetate
Show/Hide
|
C26H27ClN2O5S
|
1
|
| 1 |
IC50 = 540 nM
|
|
|
|
CP0392225
|
[(1S,2R,4R)-2-[2-[3-(1H-benzimidazol-2-yl)propyl-methylamino]ethyl]-6-fluoro-4-methoxy-1-propan-2-yl-3,4-dihydro-1H-naphthalen-2-yl] 2-methylpropanoate
Show/Hide
|
C31H42FN3O3
|
1
|
| 1 |
IC50 = 557 nM
|
|
|
|
CP0450861
|
4-bromo-1-(3-fluorophenyl)-5-phenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C25H18BrF4N3O2
|
1
|
| 1 |
IC50 = 580 nM
|
|
|
|
CP0463422
|
4-[2-(cyclopropylamino)ethyl]-1,5-diphenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C30H29F3N4O2
|
1
|
| 1 |
IC50 = 590 nM
|
|
|
|
CP0010753
|
N-[[1-[2-(tert-butylcarbamoylamino)ethyl]-4-(hydroxymethyl)piperidin-4-yl]methyl]-3,5-dichlorobenzamide
Show/Hide
|
C21H32Cl2N4O3
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0333311
|
N-[[1-[2-(tert-butylcarbamoylamino)ethyl]-4-hydroxypiperidin-4-yl]methyl]-3,5-dichlorobenzamide
Show/Hide
|
C20H30Cl2N4O3
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0389184
|
4-(difluoromethyl)-5-phenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]-1-(2,2,2-trifluoroethyl)pyrazole-3-carboxamide
Show/Hide
|
C22H17F8N3O2
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0482015
|
4-bromo-1,5-diphenyl-N-[[2-(2,2,2-trifluoroethoxy)pyridin-3-yl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C24H18BrF3N4O2
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0444163
|
(3R,5S)-3,5-dimethyl-1-(3-methylbutyl)-N-pyridin-3-yl-3,5-dihydro-2H-pyrido[3,4-e][1,4]diazepine-4-carboxamide
Show/Hide
|
C21H29N5O
|
1
|
| 1 |
IC50 = 604 nM
|
|
|
|
CP0482179
|
N-(1-benzylpyrazol-3-yl)-2-(4-methoxyphenyl)acetamide
Show/Hide
|
C19H19N3O2
|
1
|
| 1 |
IC50 = 610 nM
|
|
|
|
CP0380490
|
5-(4-bromophenyl)-N-(4-ethylphenyl)-3-(4-fluorophenyl)-3,4-dihydropyrazole-2-carboxamide
Show/Hide
|
C24H21BrFN3O
|
1
|
| 1 |
IC50 = 613 nM
|
|
|
|
CP0382628
|
(3R)-1-benzyl-3-methyl-4-(2-phenylethyl)-2,3-dihydro-1,4-benzodiazepin-5-one
Show/Hide
|
C25H26N2O
|
1
|
| 1 |
IC50 = 618 nM
|
|
|
|
CP0552233
|
5,7-dihydroxy-2-(2-hydroxyphenyl)-6-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one
Show/Hide
|
C20H20O5
|
1
|
| 1 |
IC50 = 640 nM
|
|
|
|
CP0486214
|
(2R,4S)-N-[(2-chlorophenyl)methyl]-3,3,9-trimethyl-8-thiatricyclo[4.3.0.02,4]nona-1(9),6-diene-7-carboxamide
Show/Hide
|
C19H20ClNOS
|
1
|
| 1 |
IC50 = 670 nM
|
|
|
|
CP0382627
|
(3R,5S)-N,1-dibenzyl-3,5-dimethyl-2-oxo-3,5-dihydro-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C26H27N3O2
|
1
|
| 1 |
IC50 = 682 nM
|
|
|
|
CP0542453
|
N-(4-fluorophenyl)-5-(4-methylphenyl)-5-[2-(4-methylpiperazin-1-yl)ethyl]-3-phenyl-4H-pyrazole-1-carboxamide
Show/Hide
|
C30H34FN5O
|
1
|
| 1 |
IC50 = 690 nM
|
|
|
|
CP0519502
|
(5S,7R)-N,9-dibenzyl-5,7-dimethyl-7,8-dihydro-5H-pyridazino[3,4-e][1,4]diazepine-6-carboxamide
Show/Hide
|
C24H27N5O
|
1
|
| 1 |
IC50 = 695 nM
|
|
|
|
CP0482178
|
N-(1-benzylpyrazol-3-yl)-2-(3-chlorophenyl)acetamide
Show/Hide
|
C18H16ClN3O
|
1
|
| 1 |
IC50 = 750 nM
|
|
|
|
CP0475697
|
(3R,5S)-1-benzyl-3,5-dimethyl-N-pyridin-3-yl-8-(2,2,2-trifluoroethoxy)-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C26H27F3N4O2
|
1
|
| 1 |
IC50 = 790 nM
|
|
|
|
CP0473591
|
(2R,3R)-methyl 2-(1-(4-chlorophenyl)-2-methyl-3-oxo-2,7-diazaspiro[3.5]nonane-7-carboxamido)-3-methylpentanoate
Show/Hide
|
C22H30ClN3O4
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0127886
|
N-[1-[2-(tert-butylcarbamoylamino)ethyl]azetidin-3-yl]-3,5-dichlorobenzamide
Show/Hide
|
C17H24Cl2N4O2
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0282364
|
N-[1-[2-(tert-butylcarbamoylamino)ethyl]pyrrolidin-3-yl]-3,5-dichlorobenzamide
Show/Hide
|
C18H26Cl2N4O2
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0446027
|
(3R,5S)-1-[dideuterio(phenyl)methyl]-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-pyrido[3,4-e][1,4]diazepine-4-carboxamide
Show/Hide
|
C23H25N5O
|
1
|
| 1 |
IC50 = 815 nM
|
|
|
|
CP0389185
|
4-(difluoromethyl)-1,5-diphenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C26H20F5N3O2
|
1
|
| 1 |
IC50 = 820 nM
|
|
|
|
CP0500666
|
(2S)-methyl 2-(1-(4-chlorophenyl)-2-(3-fluorophenyl)-3-oxo-2,7-diazaspiro[3.5]nonane-7-carboxamido)propanoate
Show/Hide
|
C24H25ClFN3O4
|
1
|
| 1 |
IC50 = 827 nM
|
|
|
|
CP0446070
|
(3R,5S)-N,1-dibenzyl-N,3,5-trimethyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C27H31N3O
|
1
|
| 1 |
IC50 = 835 nM
|
|
|
|
CP0382617
|
benzyl (3R,5S)-1-benzyl-3,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxylate
Show/Hide
|
C26H28N2O2
|
1
|
| 1 |
IC50 = 841 nM
|
|
|
|
CP0463423
|
4-ethenyl-1,5-diphenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C27H22F3N3O2
|
1
|
| 1 |
IC50 = 850 nM
|
|
|
|
CP0396288
|
(3R,5S)-1-benzyl-8-cyano-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C25H25N5O
|
1
|
| 1 |
IC50 = 860 nM
|
|
|
|
CP0477601
|
(3R,5S)-1-benzyl-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-pyrido[3,4-e][1,4]diazepine-4-carboxamide
Show/Hide
|
C23H25N5O
|
1
|
| 1 |
IC50 = 860 nM
|
|
|
|
CP0450864
|
4-bromo-5-phenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]-1-(2,2,2-trifluoroethyl)pyrazole-3-carboxamide
Show/Hide
|
C21H16BrF6N3O2
|
1
|
| 1 |
IC50 = 890 nM
|
|
|
|
CP0523391
|
N-(1-adamantyl)-2-[4-[2-(2,2-dimethylpropylsulfonylamino)ethyl]piperazin-1-yl]acetamide
Show/Hide
|
C23H42N4O3S
|
1
|
| 1 |
IC50 = 900 nM
|
|
|
|
CP0469497
|
N,3-bis(4-fluorophenyl)-5-methyl-3,4-dihydropyrazole-2-carboxamide
Show/Hide
|
C17H15F2N3O
|
1
|
| 1 |
IC50 = 900 nM
|
|
|
|
CP0479162
|
1-(4-chlorophenyl)-N-(3,5-difluorophenyl)-2-methyl-3-oxo-2,7-diazaspiro[3.5]nonane-7-carboxamide
Show/Hide
|
C21H20ClF2N3O2
|
1
|
| 1 |
IC50 = 920 nM
|
|
|
|
CP0396295
|
(3R,5S)-N-benzyl-1-ethyl-3,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C21H27N3O
|
1
|
| 1 |
IC50 = 922 nM
|
|
|
|
CP0408539
|
(2R,4S)-3,3,9-trimethyl-N-[(2-methylphenyl)methyl]-8-thiatricyclo[4.3.0.02,4]nona-1(9),6-diene-7-carboxamide
Show/Hide
|
C20H23NOS
|
1
|
| 1 |
IC50 = 990 nM
|
|
|
|
CP0417640
|
N-(1-adamantyl)-2-[4-[2-(tert-butylamino)-2-oxoethyl]piperazin-1-yl]acetamide
Show/Hide
|
C22H38N4O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0389187
|
1,5-diphenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C25H20F3N3O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0344603
|
(2S)-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-8-[(2R)-5-methyl-2-(prop-1-en-2-yl)hex-4-en-1-yl]-2,3-dihydro-4H-chromen-4-one
Show/Hide
|
C25H28O6
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0450628
|
(2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-en-1-yl)-3,4-dihydro-2H-1-benzopyran-4-one
Show/Hide
|
C20H20O5
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0538721
|
2-(4-hydroxyphenyl)-6-(3-methylbut-2-enyl)-5,7-bis(oxidanyl)-2,3-dihydrochromen-4-one
Show/Hide
|
C20H20O5
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0445136
|
5,7-dihydroxy-2-(3-hydroxyphenyl)-6-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one
Show/Hide
|
C20H20O5
|
1
|
| 1 |
IC50 = 1020 nM
|
|
|
|
CP0865121
|
N-(1-Benzyl-1H-pyrazol-3-yl)-2-m-tolyl-acetamide
Show/Hide
|
C19H19N3O
|
1
|
| 1 |
IC50 = 1040 nM
|
|
|
|
CP0450863
|
4-(difluoromethyl)-1-(2-fluorophenyl)-5-phenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C26H19F6N3O2
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0391825
|
N-(1-adamantyl)-2-[4-[3-(tert-butylcarbamoylamino)propyl]piperazin-1-yl]acetamide
Show/Hide
|
C24H43N5O2
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0517705
|
tert-butyl N-[2-[4-[2-(1-adamantylamino)-2-oxoethyl]piperazin-1-yl]ethyl]carbamate
Show/Hide
|
C23H40N4O3
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0539495
|
5-hydroxy-2-(2-hydroxyphenyl)-6-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one
Show/Hide
|
C20H20O4
|
1
|
| 1 |
IC50 = 1250 nM
|
|
|
|
CP0471473
|
N-butan-2-yl-1-(4-chlorophenyl)-2-(3-fluorophenyl)-3-oxo-2,7-diazaspiro[3.5]nonane-7-carboxamide
Show/Hide
|
C24H27ClFN3O2
|
1
|
| 1 |
IC50 = 1251 nM
|
|
|
|
CP0417638
|
N-[3-[4-[2-(1-adamantylamino)-2-oxoethyl]piperazin-1-yl]propyl]-2,2-dimethylpropanamide
Show/Hide
|
C24H42N4O2
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0450867
|
(2R,4S)-3,3,9-trimethyl-N-[(4-methylphenyl)methyl]-8-thiatricyclo[4.3.0.02,4]nona-1(9),6-diene-7-carboxamide
Show/Hide
|
C20H23NOS
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0429394
|
1-benzyl-4-bromo-5-phenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C26H21BrF3N3O2
|
1
|
| 1 |
IC50 = 1450 nM
|
|
|
|
CP0519761
|
(3R,5S)-1-benzyl-3,5-dimethyl-4-(1-methylimidazol-4-yl)sulfonyl-3,5-dihydro-2H-1,4-benzodiazepine
Show/Hide
|
C22H26N4O2S
|
1
|
| 1 |
IC50 = 1490 nM
|
|
|
|
CP0463421
|
4-(difluoromethyl)-1-(3-fluorophenyl)-5-phenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C26H19F6N3O2
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0408320
|
(3R,5S)-1-benzyl-8-methoxy-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C25H28N4O2
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0372729
|
benzyl N-[2-[3-[(3-chlorophenyl)-[2-oxo-2-(propan-2-ylamino)ethyl]sulfamoyl]anilino]-2-oxoethyl]-N-methylcarbamate
Show/Hide
|
C28H31ClN4O6S
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0482016
|
N-[(2-fluorophenyl)methyl]-1,5-diphenylpyrazole-3-carboxamide
Show/Hide
|
C23H18FN3O
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0425132
|
[(1S,8S,9S)-9-[2-[3-(1H-benzimidazol-2-yl)propyl-methylamino]ethyl]-3,6-diazatricyclo[6.2.2.02,7]dodeca-2,4,6-trien-9-yl] 2-methylpropanoate
Show/Hide
|
C27H35N5O2
|
1
|
| 1 |
IC50 = 2065 nM
|
|
|
|
CP0483098
|
N-(1-benzylpyrazol-3-yl)-1-(4-methoxyphenyl)cyclopropane-1-carboxamide
Show/Hide
|
C21H21N3O2
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
|
CP0396363
|
4-[2-(diethylamino)ethyl]-1,5-diphenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C31H33F3N4O2
|
1
|
| 1 |
IC50 = 2150 nM
|
|
|
|
CP0501805
|
1-(4-chlorophenyl)-2-cyclopropyl-N-(3,5-difluorophenyl)-3-oxo-2,7-diazaspiro[3.5]nonane-7-carboxamide
Show/Hide
|
C23H22ClF2N3O2
|
1
|
| 1 |
IC50 = 2258 nM
|
|
|
|
CP0470498
|
2-[[1-(4-fluorophenyl)-5-propan-2-ylpyrazol-3-yl]methyl]-3H-1,2-benzothiazole 1,1-dioxide
Show/Hide
|
C20H20FN3O2S
|
1
|
| 1 |
IC50 = 2320 nM
|
|
|
|
CP0391824
|
N-(1-adamantyl)-2-[4-(3-tert-butylsulfonylpropyl)piperazin-1-yl]acetamide
Show/Hide
|
C23H41N3O3S
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0451387
|
2-[(1-phenyl-5-propan-2-ylpyrazol-3-yl)methyl]-3H-1,2-benzothiazole 1,1-dioxide
Show/Hide
|
C20H21N3O2S
|
1
|
| 1 |
IC50 = 2520 nM
|
|
|
|
CP0475698
|
(3R,5S)-3,5-dimethyl-1-(oxan-2-ylmethyl)-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C23H30N4O2
|
1
|
| 1 |
IC50 = 2670 nM
|
|
|
|
CP0472880
|
N-[2-[4-[2-(1-adamantylamino)-2-oxoethyl]piperazin-1-yl]ethyl]-2,2-dimethylpropanamide
Show/Hide
|
C23H40N4O2
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
|
CP0449008
|
N-[[4-[2-(tert-butylcarbamoylamino)ethyl]morpholin-2-yl]methyl]-3,5-dichlorobenzamide
Show/Hide
|
C19H28Cl2N4O3
|
1
|
| 1 |
IC50 = 3300 nM
|
|
|
|
CP0491070
|
(S)-methyl 2-(1-(4-chlorophenyl)-2-(3-fluorophenyl)-3-oxo-2,7-diazaspiro[3.5]nonane-7-carboxamido)-3-hydroxypropanoate
Show/Hide
|
C24H25ClFN3O5
|
1
|
| 1 |
IC50 = 3333 nM
|
|
|
|
CP0471814
|
N-(1-benzylpyrazol-3-yl)-2-(2-methylphenyl)acetamide
Show/Hide
|
C19H19N3O
|
1
|
| 1 |
IC50 = 3400 nM
|
|
|
|
CP0382830
|
2-(3-chlorophenyl)-N-(3,5-difluorophenyl)-1-oxo-3-(pyridin-2-yl)-2,7-diazaspiro[3.5]nonane-7-carboxamide
Show/Hide
|
C25H21ClF2N4O2
|
1
|
| 1 |
IC50 = 3490 nM
|
|
|
|
CP0446775
|
2-[(1-tert-butyl-5-propan-2-ylpyrazol-3-yl)methyl]-3H-1,2-benzothiazole 1,1-dioxide
Show/Hide
|
C18H25N3O2S
|
1
|
| 1 |
IC50 = 3690 nM
|
|
|
|
CP0470499
|
N-[[4-methyl-5-(2-methylpropyl)-1-phenylpyrazol-3-yl]methyl]benzenesulfonamide
Show/Hide
|
C21H25N3O2S
|
1
|
| 1 |
IC50 = 4300 nM
|
|
|
|
CP0452711
|
(3R,5S)-1-(benzenesulfonyl)-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C23H24N4O3S
|
1
|
| 1 |
IC50 = 4695 nM
|
|
|
|
CP0417642
|
N-(1-adamantyl)-2-[4-[2-(tert-butylamino)ethyl]piperazin-1-yl]acetamide
Show/Hide
|
C22H40N4O
|
1
|
| 1 |
IC50 = 4900 nM
|
|
|
|
CP0482012
|
4-(difluoromethyl)-1-(4-fluorophenyl)-5-phenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C26H19F6N3O2
|
1
|
| 1 |
IC50 = 5000 nM
|
|
|
|
CP0459414
|
[5-(4-bromophenyl)-3-(4-fluorophenyl)-3,4-dihydropyrazol-2-yl]-phenylmethanone
Show/Hide
|
C22H16BrFN2O
|
1
|
| 1 |
IC50 = 5390 nM
|
|
|
|
CP0313143
|
N-[[5-(2-methylpropyl)-1-phenylpyrazol-3-yl]methyl]benzenesulfonamide
Show/Hide
|
C20H23N3O2S
|
1
|
| 1 |
IC50 = 5800 nM
|
|
|
|
CP0429387
|
(2S,4R)-N-[(2-methoxyphenyl)methyl]-3,3,9-trimethyl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C19H23N3O2
|
1
|
| 1 |
IC50 = 5800 nM
|
|
|
|
CP0389208
|
2-[4-(dimethylamino)phenyl]-N-(1-phenylpyrazol-3-yl)acetamide
Show/Hide
|
C19H20N4O
|
1
|
| 1 |
IC50 = 6300 nM
|
|
|
|
CP0382577
|
(3R,5S)-1-benzyl-3,5-dimethyl-4-(oxan-4-ylmethyl)-3,5-dihydro-2H-1,4-benzodiazepine
Show/Hide
|
C24H32N2O
|
1
|
| 1 |
IC50 = 7410 nM
|
|
|
|
CP0554827
|
(5S)-N-(4-bromophenyl)-5-(2-hydroxyethyl)-5-(4-methoxyphenyl)-3-pyridin-3-yl-4H-pyrazole-1-carboxamide
Show/Hide
|
C24H23BrN4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0555472
|
5-(4-bromophenyl)-N-(2-fluorophenyl)-3-(4-fluorophenyl)-3,4-dihydropyrazole-2-carboxamide
Show/Hide
|
C22H16BrF2N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0471734
|
4-chloro-5-methyl-N-[[2-(2-methylpropoxy)phenyl]methyl]-2,3-dihydro-1H-pyrrolo[3,4-c]pyrrole-6-carboxamide
Show/Hide
|
C19H24ClN3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0412185
|
N-[1-[(4-acetamidophenyl)methyl]pyrazol-3-yl]-2-[4-(dimethylamino)phenyl]acetamide
Show/Hide
|
C22H25N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0412197
|
2-[4-(dimethylamino)phenyl]-N-[1-[[4-(2-oxopyrrolidin-1-yl)phenyl]methyl]pyrazol-3-yl]acetamide
Show/Hide
|
C24H27N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0412204
|
N-(1-benzylpyrazol-3-yl)benzamide
Show/Hide
|
C17H15N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0483095
|
3-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-5-(4-propan-2-ylphenyl)-1,2,4-oxadiazole
Show/Hide
|
C21H18F2N4O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0486053
|
N-(1-benzylpyrazol-3-yl)-2-phenylacetamide
Show/Hide
|
C18H17N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0377010
|
(3R,5S)-N-benzyl-3,5-dimethyl-1,2,3,5-tetrahydro-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C19H23N3O
|
1
|
| 1 |
IC50 > 10700 nM
|
|
|
|
CP0382635
|
(3R,5S)-N,1-dibenzyl-3,5-dimethyl-3,5-dihydro-2H-pyrido[4,3-e][1,4]diazepine-4-carboxamide
Show/Hide
|
C25H28N4O
|
1
|
| 1 |
IC50 > 11000 nM
|
|
|
|
CP0444048
|
(3S,5R)-N,1-dibenzyl-3,5-dimethyl-3,5-dihydro-2H-pyrido[3,4-e][1,4]diazepine-4-carboxamide
Show/Hide
|
C25H28N4O
|
1
|
| 1 |
IC50 > 11000 nM
|
|
|
|
CP0382619
|
(3R,5S)-1-benzoyl-N-benzyl-3,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C26H27N3O2
|
1
|
| 1 |
IC50 > 11550 nM
|
|
|
|
CP0388291
|
2-(3-chloro-4-fluorophenyl)-N-(3,4-difluorophenyl)-1-oxo-3-(pyridin-2-yl)-2,7-diazaspiro[3.5]nonane-7-carboxamide
Show/Hide
|
C25H20ClF3N4O2
|
1
|
| 1 |
IC50 = 17700 nM
|
|
|
|
CP0418473
|
2-(3-cyanophenyl)-N-(3,5-difluorophenyl)-1-oxo-3-(pyridin-2-yl)-2,7-diazaspiro[3.5]nonane-7-carboxamide
Show/Hide
|
C26H21F2N5O2
|
1
|
| 1 |
IC50 = 19300 nM
|
|
|
|
CP0399519
|
5-[4-[2-(dimethylamino)ethoxy]phenyl]-N-(4-fluorophenyl)-5-(2-hydroxyethyl)-3-phenyl-4H-pyrazole-1-carboxamide
Show/Hide
|
C28H31FN4O3
|
1
|
| 1 |
IC50 > 5300 nM
|
|
|
|
CP0534094
|
(7R,9S)-N,5-dibenzyl-7,9-dimethyl-7,9-dihydro-6H-pyrimido[5,4-e][1,4]diazepine-8-carboxamide
Show/Hide
|
C24H27N5O
|
1
|
| 1 |
IC50 > 6400 nM
|
|
|
|
CP0382621
|
(3R,5S)-1-benzyl-9-methoxy-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C25H28N4O2
|
1
|
| 1 |
IC50 > 6500 nM
|
|
|
|
CP0424411
|
(4S,6R)-N,8-dibenzyl-1,4,6-trimethyl-6,7-dihydro-4H-pyrazolo[3,4-e][1,4]diazepine-5-carboxamide
Show/Hide
|
C24H29N5O
|
1
|
| 1 |
IC50 > 7300 nM
|
|
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CP0446026
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(3R,5S)-1-benzyl-3,5-dimethyl-8-methylsulfonyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
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C25H28N4O3S
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1
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| 1 |
IC50 > 8000 nM
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CP0382578
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(3R,5S)-N-benzyl-3,5-dimethyl-1-(pyridin-4-ylmethyl)-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
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C25H28N4O
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1
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| 1 |
IC50 > 8580 nM
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