Brief Information of the Compound and Protein
Compound Name
2-(3-chlorophenyl)-7-(5-fluoro-6-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-3-(pyridin-2-yl)-2,7-diazaspiro[3.5]nonan-1-one
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PubChem ID
CID: 24936281
SID: 53834369
Canonical SMILES
Fc1cc2[nH]c(nc2cc1C(F)(F)F)N1CCC2(CC1)C(N(C2=O)c1cccc(Cl)c1)c1ccccn1
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Compound Formula C26H20ClF4N5O
Compound Structure
Protein Name
Voltage-dependent T-type calcium channel subunit alpha-1H
Protein Classification
Ion channel
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Voltage-gated ion channel
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Voltage-gated calcium channel
Uniprot ID
O95180
Gene Name
CACNA1H
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 44 nM
   TI
   LI
   LO
   TS
2
IC50 = 63 nM
   TI
   LI
   LO
   TS