Brief Information of the Compound and Protein
Compound Name
2-(3-chloro-4-fluorophenyl)-N-(3,5-difluorophenyl)-1-(pyridin-2-yl)-2,7-diazaspiro[3.5]nonane-7-carboxamide
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PubChem ID
CID: 49863137
Canonical SMILES
Fc1cc(F)cc(NC(=O)N2CCC3(CN(C3c3ccccn3)c3ccc(F)c(Cl)c3)CC2)c1
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Compound Formula C25H22ClF3N4O
Compound Structure
Protein Name
Voltage-dependent T-type calcium channel subunit alpha-1H
Protein Classification
Ion channel
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Voltage-gated ion channel
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Voltage-gated calcium channel
Uniprot ID
O95180
Gene Name
CACNA1H
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 41 nM
   TI
   LI
   LO
   TS