| Compound ID |
Compound Name |
Compound Formula |
|
CP0926416
|
(E)-N-[(S)-1-((R)-2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethylamino)-1-oxopropan-2-yl]-2-cyano-3-(4-methoxyphenyl)acrylamide
Show/Hide
|
C42H41N7O4
|
2
|
| 1 |
EC50 = 1.4 nM
|
|
|
| 2 |
Ki = 3 nM
|
|
|
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CP0037119
|
1-{[(2R)-3-(benzyloxy)-1-{1-methanesulfonyl-1,2-dihydrospiro[indole-3,4'-piperidine]-1'-yl}-1-oxopropan-2-yl]carbamoyl}-1-methylethan-1-aminium
Show/Hide
|
C27H36N4O5S
|
1
|
| 1 |
EC50 = 1.43 nM
|
|
|
|
CP0946942
|
(R)-N-[3-(2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethylamino)-3-oxopropyl]-2-cyano-3-(4-methoxyphenyl)acrylamide
Show/Hide
|
C42H41N7O4
|
2
|
| 1 |
EC50 = 3.6 nM
|
|
|
| 2 |
Ki = 14 nM
|
|
|
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CP0875558
|
(R,E)-N-[2-(2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-(2-morpholinoethyl)-4H-1,2,4-triazol-3-yl)ethylamino)-2-oxoethyl]-2-cyano-3-(4-(dimethylamino)phenyl)acrylamide
Show/Hide
|
C40H45N9O4
|
2
|
| 1 |
EC50 = 6 nM
|
|
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| 2 |
Ki = 6.3 nM
|
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|
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CP0686858
|
1N-[1-benzyloxymethyl-2-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-2-oxo-(1R)-ethyl]-2-aminomethylcarboxamido-3-hydroxy-(2S)-propanamide; Trifluoroacetate
Show/Hide
|
C30H38F3N5O9S
|
1
|
| 1 |
EC50 = 7.95 nM
|
|
|
|
CP0079401
|
(6S,9R,12R)-6-cyclopropyl-8,9-dimethyl-12-[(4-methylphenyl)methyl]-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-triene-7,10,13-trione
Show/Hide
|
C30H40N4O4
|
1
|
| 1 |
EC50 = 8.2 nM
|
|
|
|
CP0901778
|
(R)-N-[2-(2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethylamino)-2-oxoethyl]-1-(4-cyano-2-methyloxazol-5-yl)piperidine-4-carboxamide
Show/Hide
|
C41H43N9O4
|
2
|
| 1 |
EC50 = 8.2 nM
|
|
|
| 2 |
Ki = 6.6 nM
|
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|
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CP0901779
|
(R,E)-N-[2-(2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethylamino)-2-oxoethyl]-2-cyano-3-(thiophen-2-yl)acrylamide
Show/Hide
|
C38H35N7O3S
|
2
|
| 1 |
EC50 = 8.6 nM
|
|
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| 2 |
Ki = 9.7 nM
|
|
|
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CP0387430
|
3-[(1S)-1-(2,3-dichloro-4-ethynylphenyl)ethyl]-1-methyl-1-[1-[5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]piperidin-4-yl]urea
Show/Hide
|
C31H33Cl2N5O
|
2
|
| 1 |
EC50 = 10.6 nM
|
|
|
| 2 |
IC50 = 156 nM
|
|
|
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CP0284752
|
(6S,9R,12R)-6-cyclopropyl-8,9-dimethyl-12-[[4-(trifluoromethyl)phenyl]methyl]-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-triene-7,10,13-trione
Show/Hide
|
C30H37F3N4O4
|
2
|
| 1 |
EC50 = 11 nM
|
|
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| 2 |
Ki = 0.1 nM
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|
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CP0158770
|
(2S)-2,6-diamino-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-naphthalen-1-yl-1-oxopropan-2-yl]hexanamide
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|
C51H67N9O6
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0885412
|
(R,E)-N-[2-(2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethylamino)-2-oxoethyl]-2-cyano-3-(4-fluorophenyl)acrylamide
Show/Hide
|
C40H36FN7O3
|
2
|
| 1 |
EC50 = 14.2 nM
|
|
|
| 2 |
Ki = 0.6 nM
|
|
|
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CP0946597
|
(R,E)-N-[2-(2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethylamino)-2-oxoethyl]-2-cyano-3-(1H)pyrrol-2yl)acrylamide
Show/Hide
|
C38H36N8O3
|
2
|
| 1 |
EC50 = 15.8 nM
|
|
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| 2 |
Ki = 8.5 nM
|
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|
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CP0260067
|
(3R,6S,9R,12R)-12-[(4-chlorophenyl)methyl]-6-cyclopropyl-3,8,9-trimethyl-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-triene-7,10,13-trione
Show/Hide
|
C30H39ClN4O4
|
1
|
| 1 |
EC50 = 18 nM
|
|
|
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CP0885411
|
(R)-N-[2-(2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethylamino)-2-oxoethyl]-3-(4-hydroxyphenyl)-propanamide
Show/Hide
|
C39H40N6O4
|
2
|
| 1 |
EC50 = 19 nM
|
|
|
| 2 |
Ki = 35 nM
|
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CP0722711
|
2-(1-amino-1-methylethylcarboxamido)-3-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-3-oxo-(2R)-propyl octanoate; Trifluoroacetate
Show/Hide
|
C30H45F3N4O8S
|
1
|
| 1 |
EC50 = 19.6 nM
|
|
|
|
CP0238556
|
(6S,9R,12R)-6-[(2S)-butan-2-yl]-12-[(4-chlorophenyl)methyl]-8,9-dimethyl-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-triene-7,10,13-trione
Show/Hide
|
C30H41ClN4O4
|
2
|
| 1 |
EC50 = 20 nM
|
|
|
| 2 |
Ki = 0.34 nM
|
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|
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CP0910876
|
(R,E)-N-[2-(2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethylamino)-2-oxoethyl]-2-cyano-3-p-tolylacrylamide
Show/Hide
|
C41H39N7O3
|
2
|
| 1 |
EC50 = 21.5 nM
|
|
|
| 2 |
Ki = 1 nM
|
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|
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CP0213740
|
(6S,9R,12R)-12-benzyl-6-cyclopropyl-8,9-dimethyl-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-triene-7,10,13-trione
Show/Hide
|
C29H38N4O4
|
2
|
| 1 |
EC50 = 23 nM
|
|
|
| 2 |
Ki = 0.1 nM
|
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|
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CP0910877
|
(R)-N-[2-(2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-(2-(piperidin-1-yl)ethyl)-4H-1,2,4-triazol-3-yl)ethylamino)-2-oxoethyl]-2-cyano-3-(4-methoxyphenyl)acrylamide
Show/Hide
|
C40H44N8O4
|
2
|
| 1 |
EC50 = 23 nM
|
|
|
| 2 |
Ki = 14 nM
|
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|
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CP0923332
|
(R,E)-N-(2-(1-(5-(2-(1H-Indol-3-yl)ethyl)-4-(4-methoxybenzyl)-4H-1,2,4-triazol-3-yl)-2-(1H-Indol-3-yl)ethylamino)-2-oxoethyl)-2-cyano-3-(4-methoxyphenyl)acrylamide
Show/Hide
|
C43H40N8O4
|
2
|
| 1 |
EC50 = 25 nM
|
|
|
| 2 |
Ki = 1.4 nM
|
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|
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CP0238497
|
(3S,6S,9R,12R)-6-cyclopropyl-12-[(4-fluorophenyl)methyl]-3,8,9-trimethyl-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-triene-7,10,13-trione
Show/Hide
|
C30H39FN4O4
|
2
|
| 1 |
EC50 = 26 nM
|
|
|
| 2 |
Ki = 10 nM
|
|
|
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CP0213761
|
(6S,9R,12R)-6-cyclopropyl-21-fluoro-12-[(4-fluorophenyl)methyl]-8,9-dimethyl-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(18),19,21-triene-7,10,13-trione
Show/Hide
|
C29H36F2N4O4
|
2
|
| 1 |
EC50 = 27 nM
|
|
|
| 2 |
Ki = 0.1 nM
|
|
|
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CP0943476
|
(R)-N-[2-(2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethylamino)-2-oxoethyl]-2-cyano-3-(4-hydroxyphenyl)acrylamide
Show/Hide
|
C40H37N7O4
|
2
|
| 1 |
EC50 = 27 nM
|
|
|
| 2 |
Ki = 3 nM
|
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CP0885413
|
(R,E)-N-[2-(2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethylamino)-2-oxoethyl]-2-cyano-3-(1H)indol-3-yl)acrylamide
Show/Hide
|
C42H38N8O3
|
2
|
| 1 |
EC50 = 28 nM
|
|
|
| 2 |
Ki = 6.3 nM
|
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CP0726922
|
(2R,5S,8R,11R)-5-cyclopropyl-11-(4-fluorobenzyl)-2,7,8-trimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione hydrochloride hydrate
Show/Hide
|
C30H42ClFN4O5
|
1
|
| 1 |
EC50 = 29 nM
|
|
|
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CP0387368
|
3-[(1S)-1-[2,3-dichloro-4-(2-cyclopropylethynyl)phenyl]ethyl]-1-methyl-1-[1-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]piperidin-4-yl]urea
Show/Hide
|
C34H37Cl2N5O
|
2
|
| 1 |
EC50 = 29.4 nM
|
|
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| 2 |
IC50 = 68.2 nM
|
|
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CP0134612
|
GHRELIN
Show/Hide
|
C147H245N45O42
|
1
|
| 1 |
EC50 = 32 nM
|
|
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CP0902846
|
(R)-2-cyano-N-[2-(1-(5-(2-(diethylamino)ethyl)-4-(4-methoxybenzyl)-4H-1,2,4-triazol-3-yl)-2-(1H-Indol-3-yl)ethylamino)-2-oxoethyl]-3-(4-methoxyphenyl)acrylamide
Show/Hide
|
C39H44N8O4
|
2
|
| 1 |
EC50 = 35 nM
|
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| 2 |
Ki = 10 nM
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CP0151994
|
(6S,12R)-12-[(4-hydroxyphenyl)methyl]-8-methyl-6-propyl-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-triene-7,10,13-trione
Show/Hide
|
C28H38N4O5
|
2
|
| 1 |
EC50 = 39 nM
|
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| 2 |
Ki = 100 nM
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CP0191601
|
(6S,9R,12R)-12-benzyl-8,9-dimethyl-6-propyl-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-triene-7,10,13-trione
Show/Hide
|
C29H40N4O4
|
1
|
| 1 |
EC50 = 40 nM
|
|
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CP0450827
|
1-[1-(5-chloro-2,3-dihydro-1H-inden-1-yl)piperidin-4-yl]-3-[(1S)-1-(2,3-dichloro-4-methoxyphenyl)ethyl]-1-methylurea
Show/Hide
|
C25H30Cl3N3O2
|
2
|
| 1 |
EC50 = 40.7 nM
|
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| 2 |
IC50 = 315 nM
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CP0869709
|
(R)-N-[2-(2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-(2-morpholinoethyl)-4H-1,2,4-triazol-3-yl)ethylamino)-2-oxoethyl]-2-cyano-3-(4-hydroxyphenyl)acrylamide
Show/Hide
|
C38H40N8O5
|
2
|
| 1 |
EC50 = 42 nM
|
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| 2 |
Ki = 64 nM
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CP0907060
|
(R,E)-N-[2-(2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethylamino)-2-oxoethyl]-2-cyano-3-phenylacrylamide
Show/Hide
|
C40H37N7O3
|
2
|
| 1 |
EC50 = 45 nM
|
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| 2 |
Ki = 9 nM
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CP0260069
|
(3R,6S,9R,12R)-6-cyclohexyl-12-[(4-fluorophenyl)methyl]-3,8,9-trimethyl-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-triene-7,10,13-trione
Show/Hide
|
C33H45FN4O4
|
1
|
| 1 |
EC50 = 49 nM
|
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CP0871673
|
(R,E)-N-[2-(2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethylamino)-2-oxoethyl]-2-cyano-3-(4-methoxyphenyl)acrylamide
Show/Hide
|
C41H39N7O4
|
2
|
| 1 |
EC50 = 50 nM
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| 2 |
Ki = 0.5 nM
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CP0493514
|
3-[(1S)-1-[2,3-dichloro-4-(2-cyclopropylethynyl)phenyl]ethyl]-1-methyl-1-[1-[5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]piperidin-4-yl]urea
Show/Hide
|
C34H37Cl2N5O
|
2
|
| 1 |
EC50 = 51 nM
|
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| 2 |
IC50 = 80 nM
|
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CP0871674
|
(S)-N-[2-((R)-2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethylamino)-2-oxoethyl]-2-amino-3-(4-methoxyphenyl)propanamide
Show/Hide
|
C40H43N7O4
|
2
|
| 1 |
EC50 = 62 nM
|
|
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| 2 |
Ki = 17 nM
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CP0049105
|
(SP)Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2
Show/Hide
|
C63H98N18O13S
|
1
|
| 1 |
EC50 = 66 nM
|
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CP0394769
|
3-[(1S)-1-(2,3-dichloro-4-methoxyphenyl)ethyl]-1-methyl-1-[1-[5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]piperidin-4-yl]urea
Show/Hide
|
C30H35Cl2N5O2
|
2
|
| 1 |
EC50 = 67 nM
|
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| 2 |
IC50 = 171 nM
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CP0773560
|
2-[1-aminomethylcarboxamido-2-hydroxy-(1S)-ethylcarboxamido]-3-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-3-oxo-(2R)-propyl octanoate; Trifluoroacatate
Show/Hide
|
C31H46F3N5O10S
|
1
|
| 1 |
EC50 = 68.2 nM
|
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CP0735614
|
1N-[1-benzyloxymethyl-2-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-2-oxo-(1R)-ethyl]-2-amino-3-hydroxy-(2S)-propanamide; Trifluoroacetate
Show/Hide
|
C28H35F3N4O8S
|
1
|
| 1 |
EC50 = 69.2 nM
|
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CP0536191
|
3-[(1S)-1-(2,3-dichloro-4-methoxyphenyl)ethyl]-1-methyl-1-[1-[5-(triazol-2-yl)-2,3-dihydro-1H-inden-1-yl]piperidin-4-yl]urea
Show/Hide
|
C27H32Cl2N6O2
|
2
|
| 1 |
EC50 = 70 nM
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| 2 |
IC50 = 240 nM
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CP0310709
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2-[1-[1-aminomethylcarboxamido-2-heptylcarbonyloxy-(1S)-ethylcarboxamido]-2-hydroxy-(1S)-ethylcarboxamido]-3-phenyl-(2S)-propanoic acid
Show/Hide
|
C25H38N4O8
|
1
|
| 1 |
EC50 = 72 nM
|
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CP0489546
|
3-[(1S)-1-(2,3-dichloro-4-methoxyphenyl)ethyl]-1-methyl-1-[1-(5-methyl-2,3-dihydro-1H-inden-1-yl)piperidin-4-yl]urea
Show/Hide
|
C26H33Cl2N3O2
|
2
|
| 1 |
EC50 = 73 nM
|
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| 2 |
IC50 = 329 nM
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CP0907057
|
(R,E)-N-[2-(2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-(2-morpholinoethyl)-4H-1,2,4-triazol-3-yl)ethylamino)-2-oxoethyl]-2-cyano-3-phenylacrylamide
Show/Hide
|
C38H40N8O4
|
2
|
| 1 |
EC50 = 73 nM
|
|
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| 2 |
Ki = 67 nM
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CP0205852
|
(6S,12R)-12-benzyl-8-methyl-6-propyl-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-triene-7,10,13-trione
Show/Hide
|
C28H38N4O4
|
2
|
| 1 |
EC50 = 83 nM
|
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| 2 |
Ki = 10 nM
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CP0536192
|
3-[(1S)-1-[2,3-dichloro-4-(2-cyclopropylethynyl)phenyl]ethyl]-1-methyl-1-[1-(5-pyrimidin-5-yl-2,3-dihydro-1H-inden-1-yl)piperidin-4-yl]urea
Show/Hide
|
C33H35Cl2N5O
|
2
|
| 1 |
EC50 = 84.8 nM
|
|
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| 2 |
IC50 = 85.9 nM
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CP0260072
|
(7R,10R,13S,16R)-13-cyclopropyl-7-[(4-fluorophenyl)methyl]-10,11-dimethyl-24-oxa-5,8,11,14-tetrazatricyclo[14.6.2.019,23]tetracosa-1(23),19,21-triene-6,9,12-trione
Show/Hide
|
C31H39FN4O4
|
1
|
| 1 |
EC50 = 85 nM
|
|
|
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CP0387427
|
3-[(1S)-1-(2,3-dichloro-4-methoxyphenyl)ethyl]-1-[1-(5-methoxy-2,3-dihydro-1H-inden-1-yl)piperidin-4-yl]-1-methylurea
Show/Hide
|
C26H33Cl2N3O3
|
2
|
| 1 |
EC50 = 85.7 nM
|
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| 2 |
IC50 = 120 nM
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CP0943475
|
(R,E)-N-[2-(2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethylamino)-2-oxoethyl]-2-cyano-3-(4-(dimethylamino)phenyl)acrylamide
Show/Hide
|
C42H42N8O3
|
2
|
| 1 |
EC50 = 89 nM
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|
|
| 2 |
Ki = 2.4 nM
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CP0536193
|
methyl 2,3-dichloro-4-[(1S)-1-[[methyl-[1-[5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]piperidin-4-yl]carbamoyl]amino]ethyl]benzoate
Show/Hide
|
C31H35Cl2N5O3
|
2
|
| 1 |
EC50 = 96 nM
|
|
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| 2 |
IC50 = 303 nM
|
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CP0462170
|
3-[(1S)-1-[2,3-dichloro-4-(2-cyclopropylethynyl)phenyl]ethyl]-1-methyl-1-[1-(5-methyl-2,3-dihydro-1H-inden-1-yl)piperidin-4-yl]urea
Show/Hide
|
C30H35Cl2N3O
|
2
|
| 1 |
EC50 = 117 nM
|
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| 2 |
IC50 = 282 nM
|
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CP0450826
|
3-[(1S)-1-(4-amino-2,3-dichlorophenyl)ethyl]-1-methyl-1-[1-[5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]piperidin-4-yl]urea
Show/Hide
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C29H34Cl2N6O
|
2
|
| 1 |
EC50 = 121 nM
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|
|
| 2 |
IC50 = 571 nM
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CP0354578
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(6S,12R,16E)-12-benzyl-8-methyl-6-propyl-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),16,18,20-tetraene-7,10,13-trione
Show/Hide
|
C28H36N4O4
|
1
|
| 1 |
EC50 = 134 nM
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|
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|
CP0885414
|
(R)-N-[2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethyl]-2-(2-(4-hydroxyphenyl)acetamido)-acetamide
Show/Hide
|
C38H38N6O4
|
2
|
| 1 |
EC50 = 155 nM
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|
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| 2 |
Ki = 23 nM
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CP0450822
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3-[(1S)-1-(2,3-dichloro-4-hydroxyphenyl)ethyl]-1-methyl-1-[1-(5-methyl-2,3-dihydro-1H-inden-1-yl)piperidin-4-yl]urea
Show/Hide
|
C25H31Cl2N3O2
|
2
|
| 1 |
EC50 = 189 nM
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|
|
| 2 |
IC50 = 1166 nM
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CP0467815
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3-[(1S)-1-(2,3-dichloro-4-pyrazin-2-ylphenyl)ethyl]-1-methyl-1-[1-[5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]piperidin-4-yl]urea
Show/Hide
|
C33H35Cl2N7O
|
3
|
| 1 |
EC50 = 194 nM
|
|
|
| 2 |
EC50 > 30000 nM
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|
|
| 3 |
IC50 = 369 nM
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CP0467814
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3-[(1S)-1-(2,3-dichloro-4-cyclopropylphenyl)ethyl]-1-methyl-1-[1-[5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]piperidin-4-yl]urea
Show/Hide
|
C32H37Cl2N5O
|
2
|
| 1 |
EC50 = 298 nM
|
|
|
| 2 |
IC50 = 2870 nM
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CP0416438
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3-[(1S)-1-[2,3-dichloro-4-(2-cyclopropylethynyl)phenyl]propyl]-1-methyl-1-[1-[5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]piperidin-4-yl]urea
Show/Hide
|
C35H39Cl2N5O
|
2
|
| 1 |
EC50 = 306 nM
|
|
|
| 2 |
IC50 = 192 nM
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CP0084690
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(3R,6R,9S,15E)-3-benzyl-9-[(2S)-butan-2-yl]-6,7-dimethyl-1,4,7,10-tetrazacyclooctadec-15-ene-2,5,8-trione
Show/Hide
|
C27H42N4O3
|
1
|
| 1 |
EC50 = 310 nM
|
|
|
|
CP0354581
|
(6S,9R,12R)-12-benzyl-6-[(2S)-butan-2-yl]-8,9-dimethyl-5,8,11,14-tetrazabicyclo[17.4.0]tricosa-1(23),19,21-triene-7,10,13-trione
Show/Hide
|
C32H46N4O3
|
2
|
| 1 |
EC50 = 360 nM
|
|
|
| 2 |
Ki = 10 nM
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CP0558710
|
3-[(1S)-1-[2,3-dichloro-4-(2-cyclopropylethynyl)phenyl]ethyl]-1-[3,3-dimethyl-1-[5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]piperidin-4-yl]-1-methylurea
Show/Hide
|
C36H41Cl2N5O
|
2
|
| 1 |
EC50 = 363 nM
|
|
|
| 2 |
IC50 = 530 nM
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|
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CP0727184
|
2-(1-amino-1-methylethylcarboxamido)-3-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-3-oxo-(2S)-propyl octanoate; trifluoroacetate
Show/Hide
|
C30H45F3N4O8S
|
1
|
| 1 |
EC50 = 378.1 nM
|
|
|
|
CP0677986
|
2-[1-amino-2-hydroxy-(1S)-ethylcarboxamido]-3-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-3-oxo-(2R)-propyl octanoate; Trifluoroacetate
Show/Hide
|
C29H43F3N4O9S
|
1
|
| 1 |
EC50 = 432.2 nM
|
|
|
|
CP0387429
|
3-[(1S)-2-cyclopropyl-1-(2,3-dichloro-4-methoxyphenyl)ethyl]-1-methyl-1-[1-[5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]piperidin-4-yl]urea
Show/Hide
|
C33H39Cl2N5O2
|
2
|
| 1 |
EC50 = 439 nM
|
|
|
| 2 |
IC50 = 1800 nM
|
|
|
|
CP0650732
|
2-[1-aminomethylcarboxamido-2-hydroxy-(1S)-ethylcarboxamido]-3-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-3-oxo-(2S)-propyl octanoate; trifluoroactate
Show/Hide
|
C31H46F3N5O10S
|
1
|
| 1 |
EC50 = 448.5 nM
|
|
|
|
CP0416439
|
N-[(1S)-1-(2,3-dichloro-4-pyrazin-2-ylphenyl)ethyl]-2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonane-7-carboxamide
Show/Hide
|
C34H35Cl2N7O
|
3
|
| 1 |
EC50 = 483 nM
|
|
|
| 2 |
EC50 > 30000 nM
|
|
|
| 3 |
IC50 = 1210 nM
|
|
|
|
CP0566619
|
3-[(1S)-2-cyclopropyl-1-(2,3-dichloro-4-pyrazin-2-ylphenyl)ethyl]-1-methyl-1-[1-[5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]piperidin-4-yl]urea
Show/Hide
|
C36H39Cl2N7O
|
2
|
| 1 |
EC50 = 484 nM
|
|
|
| 2 |
IC50 = 4540 nM
|
|
|
|
CP0094817
|
(6S,9R,12R)-12-benzyl-6-[(2S)-butan-2-yl]-8,9-dimethyl-2-oxa-5,8,11,14-tetrazabicyclo[15.4.0]henicosa-1(21),17,19-triene-7,10,13-trione
Show/Hide
|
C29H40N4O4
|
2
|
| 1 |
EC50 = 530 nM
|
|
|
| 2 |
Ki = 100 nM
|
|
|
|
CP0450824
|
3-[(1S)-1-[2,3-dichloro-4-(2-cyclopropylethynyl)phenyl]ethyl]-1-methyl-1-[1-(5-pyrimidin-2-yl-2,3-dihydro-1H-inden-1-yl)piperidin-4-yl]urea
Show/Hide
|
C33H35Cl2N5O
|
2
|
| 1 |
EC50 = 634 nM
|
|
|
| 2 |
IC50 = 798 nM
|
|
|
|
CP0084691
|
(6S,9R,12R)-6-cyclopropyl-12-[(4-fluorophenyl)methyl]-4,8,9-trimethyl-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-triene-7,10,13-trione
Show/Hide
|
C30H39FN4O4
|
2
|
| 1 |
EC50 = 760 nM
|
|
|
| 2 |
Ki = 0.1 nM
|
|
|
|
CP0536248
|
3-[(1S)-1-[2,3-dichloro-4-(2-cyclopropylethynyl)phenyl]ethyl]-1-ethyl-1-[1-[5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]piperidin-4-yl]urea
Show/Hide
|
C35H39Cl2N5O
|
2
|
| 1 |
EC50 = 937 nM
|
|
|
| 2 |
IC50 = 2920 nM
|
|
|
|
CP0482305
|
3-[(1S)-2-cyclopropyl-1-(2,3-dichlorophenyl)ethyl]-1-methyl-1-[1-[5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]piperidin-4-yl]urea
Show/Hide
|
C32H37Cl2N5O
|
2
|
| 1 |
EC50 = 970 nM
|
|
|
| 2 |
IC50 = 5400 nM
|
|
|
|
CP0478662
|
3-[(1S)-1-[2,3-dichloro-4-(2-cyclopropylethynyl)phenyl]ethyl]-1-methyl-1-[1-[(1S)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]piperidin-4-yl]urea
Show/Hide
|
C34H37Cl2N5O
|
2
|
| 1 |
EC50 = 1276 nM
|
|
|
| 2 |
IC50 = 1276 nM
|
|
|
|
CP0538072
|
3-[(1R)-1-(2,3-dichloro-4-pyrazin-2-ylphenyl)-2,2,2-trifluoroethyl]-1-methyl-1-[1-[5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]piperidin-4-yl]urea
Show/Hide
|
C33H32Cl2F3N7O
|
2
|
| 1 |
EC50 = 2164 nM
|
|
|
| 2 |
IC50 = 8080 nM
|
|
|
|
CP0531872
|
N-[(3R,4S)-1-(benzenesulfonyl)-4-[[(3S)-piperidin-3-yl]carbamoyl]pyrrolidin-3-yl]-1-cyclopropylimidazole-4-carboxamide
Show/Hide
|
C23H30N6O4S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0938185
|
trans-N-((3R,4R)-3-((2-(Dimethylamino)ethyl)carbamoyl)-1-(phenylsulfonyl)piperidin-4-yl)-5-methyl-1H-indole-2-carboxamide
Show/Hide
|
C26H33N5O4S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0387432
|
N-[(2,3-dichloro-4-pyrazin-2-ylphenyl)methyl]-2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonane-7-carboxamide
Show/Hide
|
C33H33Cl2N7O
|
2
|
| 1 |
EC50 > 30000 nM
|
|
|
| 2 |
IC50 = 4010 nM
|
|
|
|
CP0457386
|
1-methyl-3-[(2-methylimidazo[2,1-b][1,3]thiazol-6-yl)methyl]-1-(1-methylpiperidin-4-yl)urea
Show/Hide
|
C15H23N5OS
|
2
|
| 1 |
EC50 > 30000 nM
|
|
|
| 2 |
IC50 > 30000 nM
|
|
|
|
CP0457387
|
1-methyl-3-[1-(2-methylimidazo[2,1-b][1,3]thiazol-6-yl)ethyl]-1-(1-methylpiperidin-4-yl)urea
Show/Hide
|
C16H25N5OS
|
2
|
| 1 |
EC50 > 30000 nM
|
|
|
| 2 |
IC50 > 30000 nM
|
|
|
|
CP0476459
|
3-[(2,3-dichloro-4-pyrazin-2-ylphenyl)methyl]-1-methyl-1-[1-[5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]piperidin-4-yl]urea
Show/Hide
|
C32H33Cl2N7O
|
2
|
| 1 |
EC50 > 30000 nM
|
|
|
| 2 |
IC50 = 2330 nM
|
|
|
|
CP0545879
|
2-chloro-5-ethyl-N-[[6-[3-(4-methylpiperazin-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]benzamide
Show/Hide
|
C25H30ClN5O4S2
|
1
|
| 1 |
IC50 = 0.078 nM
|
|
|
|
CP0677002
|
(S)-6-(4-chlorophenyl)-3-((1-isopropylpiperidin-3-yl)methyl)-2-o-tolylquinazolin-4(3H)-one
Show/Hide
|
C30H32ClN3O
|
1
|
| 1 |
IC50 = 0.12 nM
|
|
|
|
CP0537743
|
2-chloro-N-[[6-[3-(4-methylpiperazin-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]-5-pyrrol-1-ylbenzamide
Show/Hide
|
C27H29ClN6O4S2
|
1
|
| 1 |
IC50 = 0.15 nM
|
|
|
|
CP0494289
|
2-chloro-4-cyano-N-[[6-[3-(4-methylpiperazin-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]-5-pyrrolidin-1-ylbenzamide
Show/Hide
|
C28H32ClN7O4S2
|
1
|
| 1 |
IC50 = 0.24 nM
|
|
|
|
CP0947416
|
rac-2-(4-Chlorophenyl)-5-(2-methylphenyl)-6-{[1-(propan-2-yl)piperidin-3-yl]methyl}-2,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
Show/Hide
|
C27H30ClN5O
|
1
|
| 1 |
IC50 = 0.28 nM
|
|
|
|
CP0410659
|
2-chloro-N-[[6-[3-(4-methylpiperazin-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]-5-pyrrolidin-1-ylbenzamide
Show/Hide
|
C27H33ClN6O4S2
|
1
|
| 1 |
IC50 = 0.29 nM
|
|
|
|
CP0414994
|
2,4-dichloro-N-[[6-[3-(4-methylpiperazin-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]-5-pyrazol-1-ylbenzamide
Show/Hide
|
C26H27Cl2N7O4S2
|
1
|
| 1 |
IC50 = 0.31 nM
|
|
|
|
CP0547512
|
2-chloro-5-ethoxy-N-[[6-[3-(4-methylpiperazin-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]benzamide
Show/Hide
|
C25H30ClN5O5S2
|
1
|
| 1 |
IC50 = 0.31 nM
|
|
|
|
CP0396758
|
2-chloro-5-cyclopropyl-N-[[6-[3-(4-methylpiperazin-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]benzamide
Show/Hide
|
C26H30ClN5O4S2
|
1
|
| 1 |
IC50 = 0.33 nM
|
|
|
|
CP0542160
|
2-chloro-4-cyano-N-[[6-(1-methylpiperidin-4-yl)sulfonyl-1,3-benzothiazol-2-yl]carbamoyl]-5-pyrrolidin-1-ylbenzamide
Show/Hide
|
C26H27ClN6O4S2
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0556742
|
2-chloro-N-[[6-[3-(diethylamino)propylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]-5-pyrrol-1-ylbenzamide
Show/Hide
|
C26H28ClN5O4S2
|
1
|
| 1 |
IC50 = 0.43 nM
|
|
|
|
CP0498623
|
2-chloro-N-[[6-[3-(4-methylpiperazin-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]-4-(3-methylpyrazol-1-yl)benzamide
Show/Hide
|
C27H30ClN7O4S2
|
1
|
| 1 |
IC50 = 0.48 nM
|
|
|
|
CP0494290
|
2-chloro-N-[[6-[3-(4-methylpiperazin-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]-5-(3-methylpyrazol-1-yl)benzamide
Show/Hide
|
C27H30ClN7O4S2
|
1
|
| 1 |
IC50 = 0.53 nM
|
|
|
|
CP0396757
|
5-chloro-1-methyl-N-[[6-[3-(4-methylpiperazin-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]indole-6-carboxamide
Show/Hide
|
C26H29ClN6O4S2
|
1
|
| 1 |
IC50 = 0.57 nM
|
|
|
|
CP0542159
|
2-chloro-4-methoxy-N-[[6-[3-(4-methylpiperazin-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]-5-pyrazol-1-ylbenzamide
Show/Hide
|
C27H30ClN7O5S2
|
1
|
| 1 |
IC50 = 0.62 nM
|
|
|
|
CP0487683
|
2-chloro-N-[[6-[3-(4-methylpiperazin-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]-5-pyrazol-1-ylbenzamide
Show/Hide
|
C26H28ClN7O4S2
|
1
|
| 1 |
IC50 = 0.67 nM
|
|
|
|
CP0480500
|
2-chloro-N-[[6-[3-(4-methylpiperazin-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]-5-pyridin-2-ylbenzamide
Show/Hide
|
C28H29ClN6O4S2
|
1
|
| 1 |
IC50 = 0.69 nM
|
|
|
|
CP0548316
|
2-chloro-N-[[6-[3-(4-methylpiperazin-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]-5-morpholin-4-ylbenzamide
Show/Hide
|
C27H33ClN6O5S2
|
1
|
| 1 |
IC50 = 0.77 nM
|
|
|
|
CP0859448
|
2-(3-ethoxyphenyl)-5-(2-methylpyridin-3-yl)-6-(((S)-1-(((R)-tetrahydrofuran-2-yl)methyl)piperidin-3-yl)methyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
|
C30H36N6O3
|
1
|
| 1 |
IC50 = 0.91 nM
|
|
|
|
CP0476041
|
2-chloro-N-[[6-(1-methylpiperidin-4-yl)sulfonyl-1,3-benzothiazol-2-yl]carbamoyl]-5-pyrrolidin-1-ylbenzamide
Show/Hide
|
C25H28ClN5O4S2
|
1
|
| 1 |
IC50 = 0.92 nM
|
|
|
|
CP0732542
|
rac-2-(4-Fluorophenyl)-6-((1-isopropylpiperidin-3-yl)methyl)-5-o-tolyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
|
C27H30FN5O
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0761780
|
2-(4-Chlorophenyl)-6-{[(3R)-1-(2-methoxyethyl)piperidin-3-yl]methyl}-5-(2-methylphenyl)-2,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
Show/Hide
|
C27H30ClN5O2
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0410663
|
2-chloro-5-(3,5-dimethylpyrazol-1-yl)-N-[[6-[3-(4-methylpiperazin-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]benzamide
Show/Hide
|
C28H32ClN7O4S2
|
1
|
| 1 |
IC50 = 1.3 nM
|
|
|
|
CP0476036
|
2-chloro-N-[[6-[3-(4-methylpiperazin-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]benzamide
Show/Hide
|
C23H26ClN5O4S2
|
1
|
| 1 |
IC50 = 1.3 nM
|
|
|
|
CP0965220
|
rac-6-(4-Chlorophenyl)-3-((1-isopropylpiperidin-3-yl)methyl)-2-o-tolylthieno[3,2-d]pyrimidin-4(3H)-one
Show/Hide
|
C28H30ClN3OS
|
1
|
| 1 |
IC50 = 1.5 nM
|
|
|
|
CP0893152
|
(S)-6-((1-(Cyclobutylmethyl)piperidin-3-yl)methyl)-2-(3-methoxyphenyl)-5-(2-methylpyridin-3-yl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
|
C29H34N6O2
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0898825
|
rac-2-(3-Chlorophenyl)-6-((1-isopropylpiperidin-3-yl)methyl)-5-o-tolyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
|
C27H30ClN5O
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0800584
|
(S)-6-((1-Isopropylpiperidin-3-yl)methyl)-2-(3-methoxyphenyl)-5-(2-methylpyridin-3-yl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
|
C27H32N6O2
|
1
|
| 1 |
IC50 = 1.7 nM
|
|
|
|
CP0893150
|
2-(3-Methoxyphenyl)-6-(((S)-1-((S)-1-methoxypropan-2-yl)piperidin-3-yl)methyl)-5-(2-methylpyridin-3-yl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
|
C28H34N6O3
|
1
|
| 1 |
IC50 = 1.7 nM
|
|
|
|
CP0767323
|
rac-6-((1-Isopropylpiperidin-3-yl)methyl)-2-(3-methoxyphenyl)-5-o-tolyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
|
C28H33N5O2
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0903935
|
(S)-6-((1-(Furan-2-ylmethyl)piperidin-3-yl)methyl)-2-(3-methoxyphenyl)-5-(2-methylpyridin-3-yl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
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C29H30N6O3
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1
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| 1 |
IC50 = 2.7 nM
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CP0544639
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2-chloro-N-[[6-[3-(diethylamino)propylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]-5-morpholin-4-ylbenzamide
Show/Hide
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C26H32ClN5O5S2
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1
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| 1 |
IC50 = 2.9 nM
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CP0480526
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2-chloro-N-[[6-[3-(diethylamino)propylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]-5-pyrazol-1-ylbenzamide
Show/Hide
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C25H27ClN6O4S2
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1
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| 1 |
IC50 = 3.9 nM
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CP0413598
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2-chloro-N-[[6-[3-(4-methyl-1,4-diazepan-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]benzamide
Show/Hide
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C24H28ClN5O4S2
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1
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| 1 |
IC50 = 4.2 nM
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CP0077530
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1-[2-[[2-chloro-4-(triazol-2-yl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-2-(2-methylimidazo[2,1-b][1,3]thiazol-6-yl)ethanone
Show/Hide
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C24H26ClN7OS
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3
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| 1 |
IC50 = 4.6 nM
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| 2 |
Ki = 5.495 nM
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| 3 |
Ki = 7 nM
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CP0842291
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5-(2-Methylpyridin-3-yl)-2-(3-propoxyphenyl)-6-(((S)-1-(((R)-tetrahydrofuran-2-yl)methyl)piperidin-3-yl)methyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
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C31H38N6O3
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1
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| 1 |
IC50 = 4.8 nM
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CP0864776
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6-(((S)-1-((S)-2-Ethoxypropyl)piperidin-3-yl)methyl)-2-(3-methoxyphenyl)-5-(2-methylpyridin-3-yl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
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C29H36N6O3
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1
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| 1 |
IC50 = 5 nM
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CP0677604
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2-(3-Methoxyphenyl)-5-(2-methylpyridin-3-yl)-6-(((S)-1-(((R)-tetrahydrofuran-2-yl)methyl)piperidin-3-yl)methyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
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C29H34N6O3
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1
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| 1 |
IC50 = 5.1 nM
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CP0545880
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2-chloro-5-ethynyl-N-[[6-[3-(4-methylpiperazin-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]benzamide
Show/Hide
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C25H26ClN5O4S2
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1
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| 1 |
IC50 = 5.1 nM
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CP0959399
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(S)-6-((1-Isobutylpiperidin-3-yl)methyl)-2-(3-methoxyphenyl)-5-(2-methylpyridin-3-yl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
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C28H34N6O2
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1
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| 1 |
IC50 = 5.7 nM
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CP0767324
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(S)-6-((1-(2-Methoxyethyl)piperidin-3-yl)methyl)-2-(3-methoxyphenyl)-5-(2-methylpyridin-3-yl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
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C27H32N6O3
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1
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| 1 |
IC50 = 6.1 nM
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CP0052201
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2-chloro-N-[[6-(1-methylpiperidin-4-yl)sulfonyl-1,3-benzothiazol-2-yl]carbamoyl]-5-morpholin-4-ylbenzamide
Show/Hide
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C25H28ClN5O5S2
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1
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| 1 |
IC50 = 6.7 nM
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CP0400202
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5-chloro-1-methyl-N-[[6-(1-methylpiperidin-4-yl)sulfonyl-1,3-benzothiazol-2-yl]carbamoyl]-2,3-dihydroindole-6-carboxamide
Show/Hide
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C24H26ClN5O4S2
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1
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| 1 |
IC50 = 7.2 nM
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CP0767322
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rac-6-((1-Isopropylpiperidin-3-yl)methyl)-2-(4-methoxyphenyl)-5-o-tolyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
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C28H33N5O2
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1
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| 1 |
IC50 = 7.3 nM
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CP0898826
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2-(3-Methoxyphenyl)-5-(2-methylpyridin-3-yl)-6-(((3S)-1-((tetrahydrofuran-2-yl)methyl)piperidin-3-yl)methyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
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C29H34N6O3
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1
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| 1 |
IC50 = 7.6 nM
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CP0414343
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2-chloro-4-ethoxy-N-[[6-(1-methylpiperidin-4-yl)sulfonyl-1,3-benzothiazol-2-yl]carbamoyl]-5-pyrazol-1-ylbenzamide
Show/Hide
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C26H27ClN6O5S2
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1
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| 1 |
IC50 = 8 nM
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CP0379173
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2-chloro-N-[[6-[3-(2-methoxyethylamino)propylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]benzamide
Show/Hide
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C21H23ClN4O5S2
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1
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| 1 |
IC50 = 8.6 nM
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CP0536596
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2-chloro-N-[[6-[3-(dimethylamino)propylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]benzamide
Show/Hide
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C20H21ClN4O4S2
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1
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| 1 |
IC50 = 8.7 nM
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CP0482054
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2-chloro-N-[[6-[3-(4-methylpiperazin-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]-3-pyrazol-1-ylbenzamide
Show/Hide
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C26H28ClN7O4S2
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1
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| 1 |
IC50 = 8.8 nM
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CP0659811
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2-(3-Isopropoxyphenyl)-5-(2-methylpyridin-3-yl)-6-(((S)-1-(((R)-tetrahydrofuran-2-yl)methyl)piperidin-3-yl)methyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
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C31H38N6O3
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1
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| 1 |
IC50 = 11 nM
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CP0881785
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(S)-6-((1-(Cyclopentylmethyl)piperidin-3-yl)methyl)-2-(3-methoxyphenyl)-5-(2-methylpyridin-3-yl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
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C30H36N6O2
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1
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| 1 |
IC50 = 12 nM
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CP0898824
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rac-4-(6-((1-Isopropylpiperidin-3-yl)methyl)-7-oxo-5-o-tolyl-6,7-dihydro-2H-pyrazolo[4,3-d]pyrimidin-2-yl)benzonitrile
Show/Hide
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C28H30N6O
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1
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| 1 |
IC50 = 12 nM
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CP0508618
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2-(4-methoxyphenyl)-1-[2-(5-pyrimidin-2-yl-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
Show/Hide
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C29H32N4O2
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1
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| 1 |
IC50 = 12.59 nM
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CP0536598
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2-chloro-N-[[6-[3-(diethylamino)propylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]benzamide
Show/Hide
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C22H25ClN4O4S2
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1
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| 1 |
IC50 = 13 nM
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CP0337820
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1-[2-[[2-chloro-4-(triazol-2-yl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-2-(4-methoxyphenoxy)ethanone
Show/Hide
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C25H28ClN5O3
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2
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| 1 |
IC50 = 14 nM
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| 2 |
Ki = 11 nM
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CP0859447
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2-(3-Methoxyphenyl)-5-(2-methylpyridin-3-yl)-6-(((S)-1-(((S)-tetrahydrofuran-2-yl)methyl)piperidin-3-yl)methyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
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C29H34N6O3
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1
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| 1 |
IC50 = 15 nM
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CP0388289
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2-chloro-N-[[6-(1-methylpiperidin-4-yl)sulfonyl-1,3-benzothiazol-2-yl]carbamoyl]-5-pyrazol-1-ylbenzamide
Show/Hide
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C24H23ClN6O4S2
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1
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| 1 |
IC50 = 15 nM
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CP0410496
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1-[2-[(2-chloro-4-pyrimidin-2-ylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-2-(4-methoxyphenyl)ethanone
Show/Hide
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C27H29ClN4O2
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1
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| 1 |
IC50 = 15.85 nM
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CP0692360
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6-(4-Chlorophenyl)-3-{[(3R)-1-(2-methoxyethyl)piperidin-3-yl]methyl}-2-(2-methylphenyl)thieno[3,2-d]pyrimidin-4(3H)-one
Show/Hide
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C28H30ClN3O2S
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1
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| 1 |
IC50 = 16 nM
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CP0867282
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2-(3-Methoxyphenyl)-5-(2-methylpyridin-3-yl)-6-(((3S)-1-(oxetan-2-ylmethyl)piperidin-3-yl)methyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
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C28H32N6O3
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1
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| 1 |
IC50 = 23 nM
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CP0379174
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2-chloro-N-[(6-methylsulfonyl-1,3-benzothiazol-2-yl)carbamoyl]-5-pyrrol-1-ylbenzamide
Show/Hide
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C20H15ClN4O4S2
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1
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| 1 |
IC50 = 23 nM
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CP0237836
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2-(2-methylimidazo[2,1-b][1,3]thiazol-6-yl)-1-[2-[[4-(triazol-2-yl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
Show/Hide
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C24H27N7OS
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2
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| 1 |
IC50 = 25 nM
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| 2 |
Ki = 69 nM
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CP0688641
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2-(3-(Difluoromethoxy)phenyl)-5-(2-methylpyridin-3-yl)-6-(((S)-1-(((R)-tetrahydrofuran-2-yl)methyl)piperidin-3-yl)methyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
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C29H32F2N6O3
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1
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| 1 |
IC50 = 27 nM
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CP0396759
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2-chloro-N-[[6-[2-(propan-2-ylamino)ethylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]benzamide
Show/Hide
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C20H21ClN4O4S2
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1
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| 1 |
IC50 = 27 nM
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CP0522545
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2-(5-methoxypyridin-2-yl)-1-[2-[5-(1,3-thiazol-2-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
Show/Hide
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C27H30N4O2S
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1
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| 1 |
IC50 = 30.2 nM
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CP0732543
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rac-3-(6-((1-Isopropylpiperidin-3-yl)methyl)-7-oxo-5-o-tolyl-6,7-dihydro-2H-pyrazolo[4,3-d]pyrimidin-2-yl)benzonitrile
Show/Hide
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C28H30N6O
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1
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| 1 |
IC50 = 32 nM
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CP0414995
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2-chloro-N-[[6-(1-methylpiperidin-4-yl)sulfonyl-1,3-benzothiazol-2-yl]carbamoyl]-5-(5-methylpyrazol-1-yl)benzamide
Show/Hide
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C25H25ClN6O4S2
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1
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| 1 |
IC50 = 33 nM
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CP0379667
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2-(5-methoxypyridin-2-yl)-1-[2-(5-pyrimidin-2-yl-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
Show/Hide
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C28H31N5O2
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1
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| 1 |
IC50 = 37.15 nM
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CP0905405
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6-(((S)-1-((R)-2-Ethoxypropyl)piperidin-3-yl)methyl)-2-(3-methoxyphenyl)-5-(2-methylpyridin-3-yl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
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C29H36N6O3
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1
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| 1 |
IC50 = 40 nM
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CP0659810
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rac-4-[6-{[1-(2-Methoxyethyl)piperidin-3-yl]methyl}-5-(2-methylpyridin-3-yl)-7-oxo-6,7-dihydro-2H-pyrazolo[4,3-d]pyrimidin-2-yl]benzonitrile
Show/Hide
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C27H29N7O2
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1
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| 1 |
IC50 = 44 nM
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CP0410658
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2-chloro-N-[[6-(2-pyrrolidin-1-ylethylsulfonyl)-1,3-benzothiazol-2-yl]carbamoyl]benzamide
Show/Hide
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C21H21ClN4O4S2
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1
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| 1 |
IC50 = 44 nM
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CP0213038
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6-(4-chlorophenyl)-3-{[(3S)-1-isopropylpiperidin-3-yl]methyl}-2-methylquinazolin-4(3H)-one
Show/Hide
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C24H28ClN3O
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1
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| 1 |
IC50 = 52 nM
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CP0881786
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2-(4-Methoxyphenyl)-5-(2-methylpyridin-3-yl)-6-(((S)-1-(((R)-tetrahydrofuran-2-yl)methyl)piperidin-3-yl)methyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
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C29H34N6O3
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1
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| 1 |
IC50 = 52 nM
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CP0126754
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1-[2-[[2-chloro-4-(2-methylpropoxy)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-2-(6-methoxypyridin-3-yl)oxyethanone
Show/Hide
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C26H34ClN3O4
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2
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| 1 |
IC50 = 59 nM
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| 2 |
Ki = 17 nM
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CP0688178
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2-(4-Chlorophenyl)-6-{[(3R)-1-(2-methoxyethyl)piperidin-3-yl]methyl}-5-(2-methylphenyl)[1,3]thiazolo[4,5-d]pyrimidin-7(6H)-one
Show/Hide
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C27H29ClN4O2S
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1
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| 1 |
IC50 = 59 nM
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CP0905404
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2-(3-Methoxyphenyl)-5-(2-methylpyridin-3-yl)-6-(((3S)-1-((tetrahydrofuran-3-yl)methyl)piperidin-3-yl)methyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
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C29H34N6O3
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1
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| 1 |
IC50 = 60 nM
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CP0548314
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2-chloro-N-[[6-(1-methylpiperidin-4-yl)sulfonyl-1,3-benzothiazol-2-yl]carbamoyl]benzamide
Show/Hide
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C21H21ClN4O4S2
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1
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| 1 |
IC50 = 65 nM
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CP0482055
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2-chloro-N-[(6-methoxy-1,3-benzothiazol-2-yl)carbamoyl]benzamide
Show/Hide
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C16H12ClN3O3S
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1
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| 1 |
IC50 = 76 nM
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CP0536597
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2-chloro-N-[[6-[2-(4-methylpiperazin-1-yl)ethylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]benzamide
Show/Hide
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C22H24ClN5O4S2
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1
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| 1 |
IC50 = 83 nM
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CP0139619
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2-(1,3-benzothiazol-2-yl)-1-[2-[[4-(2-methylpropoxy)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
Show/Hide
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C27H33N3O2S
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2
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| 1 |
IC50 = 86 nM
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| 2 |
Ki = 25 nM
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CP0211931
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1-[2-[[2-chloro-4-(2-methylpropoxy)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-2-(4-methoxyphenoxy)ethanone
Show/Hide
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C27H35ClN2O4
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2
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| 1 |
IC50 = 86 nM
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| 2 |
Ki = 20 nM
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CP0139744
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2-(2-methylimidazo[2,1-b][1,3]thiazol-6-yl)-1-[2-[(4-pyrimidin-2-ylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
Show/Hide
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C26H28N6OS
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2
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| 1 |
IC50 = 90 nM
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| 2 |
Ki = 14 nM
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CP0211932
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2-(4-methoxyphenoxy)-1-[2-[[4-(triazol-2-yl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
Show/Hide
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C25H29N5O3
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2
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| 1 |
IC50 = 102 nM
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| 2 |
Ki = 14 nM
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CP0487203
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3-[(1S)-1-(2,3-dichloro-4-ethynylphenyl)ethyl]-1-methyl-1-[1-(5-methyl-2,3-dihydro-1H-inden-1-yl)piperidin-4-yl]urea
Show/Hide
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C27H31Cl2N3O
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1
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| 1 |
IC50 = 106 nM
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CP0416277
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2-(2H-indazol-3-yl)-1-[2-[[4-(2-methylpropoxy)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
Show/Hide
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C27H34N4O2
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2
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| 1 |
IC50 = 120 nM
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| 2 |
Ki = 14 nM
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CP0893151
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(S)-2-(3-Methoxyphenyl)-5-(2-methylpyridin-3-yl)-6-((1-(oxazol-5-ylmethyl)piperidin-3-yl)methyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
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C28H29N7O3
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1
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| 1 |
IC50 = 120 nM
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CP0903934
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2-(3-Methoxyphenyl)-5-(2-methylpyridin-3-yl)-6-(((3S)-1-((tetrahydro-2H-pyran-2-yl)methyl)piperidin-3-yl)methyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
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C30H36N6O3
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1
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| 1 |
IC50 = 120 nM
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CP0410662
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2-chloro-N-[(6-methylsulfonyl-1,3-benzothiazol-2-yl)carbamoyl]benzamide
Show/Hide
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C16H12ClN3O4S2
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1
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| 1 |
IC50 = 120 nM
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CP0450829
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3-[(1S)-1-[2,3-dichloro-4-(2-cyclopropylethynyl)phenyl]ethyl]-1-methyl-1-[1-[5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]pyrrolidin-3-yl]urea
Show/Hide
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C33H35Cl2N5O
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1
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| 1 |
IC50 = 148 nM
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CP0842288
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5-(2-Methylpyridin-3-yl)-2-phenyl-6-(((S)-1-(((R)-tetrahydrofuran-2-yl)methyl)piperidin-3-yl)methyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
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C28H32N6O2
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1
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| 1 |
IC50 = 190 nM
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CP0857540
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(S)-6-((1-(Cyclohexylmethyl)piperidin-3-yl)methyl)-2-(3-methoxyphenyl)-5-(2-methylpyridin-3-yl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
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C31H38N6O2
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1
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| 1 |
IC50 = 200 nM
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CP0126756
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2-(6-chloroimidazo[1,2-a]pyridin-2-yl)-1-[2-[[4-(triazol-2-yl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
Show/Hide
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C25H26ClN7O
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2
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| 1 |
IC50 = 204 nM
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| 2 |
Ki = 23 nM
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CP0548315
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2,6-dichloro-N-[(6-methoxy-1,3-benzothiazol-2-yl)carbamoyl]benzamide
Show/Hide
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C16H11Cl2N3O3S
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1
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| 1 |
IC50 = 210 nM
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CP0207825
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1-[2-[(2,2-dimethyl-3,4-dihydrochromen-6-yl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-2-(4-methoxyphenoxy)ethanone
Show/Hide
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C28H36N2O4
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5
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| 1 |
IC50 = 211 nM
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| 2 |
IC50 = 213.8 nM
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| 3 |
Ki = 213.8 nM
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| 4 |
Ki = 407.38 nM
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| 5 |
Ki = 408 nM
|
|
|
|
CP0476076
|
1-[2-[(2-chlorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-2-(4-methoxyphenoxy)ethanone
Show/Hide
|
C23H27ClN2O3
|
2
|
| 1 |
IC50 = 231 nM
|
|
|
| 2 |
Ki = 445 nM
|
|
|
|
CP0127627
|
2-(2-methylimidazo[2,1-b][1,3]thiazol-6-yl)-1-[2-[(4-pyrazol-1-ylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
Show/Hide
|
C25H28N6OS
|
2
|
| 1 |
IC50 = 298 nM
|
|
|
| 2 |
Ki = 206 nM
|
|
|
|
CP0126757
|
2-(6-chloroimidazo[1,2-a]pyridin-2-yl)-1-[2-[(4-pyrimidin-2-ylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
Show/Hide
|
C27H27ClN6O
|
2
|
| 1 |
IC50 = 321 nM
|
|
|
| 2 |
Ki = 27 nM
|
|
|
|
CP0754348
|
(S)-2-Cyclohexyl-6-((1-(2-methoxyethyl)piperidin-3-yl)methyl)-5-(2-methylpyridin-3-yl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
|
C26H36N6O2
|
1
|
| 1 |
IC50 = 370 nM
|
|
|
|
CP0362730
|
2-(4-methoxyphenyl)-1-[2-[(6-propoxypyridin-3-yl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
Show/Hide
|
C25H33N3O3
|
2
|
| 1 |
IC50 = 407 nM
|
|
|
| 2 |
Ki = 114 nM
|
|
|
|
CP0257632
|
2-(4-methoxyphenoxy)-1-[2-[(4-pyrazol-1-ylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
Show/Hide
|
C26H30N4O3
|
2
|
| 1 |
IC50 = 442 nM
|
|
|
| 2 |
Ki = 152 nM
|
|
|
|
CP0525469
|
6-(2-chloro-4-ethoxy-5-morpholin-4-ylphenyl)-3-[6-(1-methylpiperidin-4-yl)sulfonyl-1,3-benzothiazol-2-yl]-1H-pyridin-2-one
Show/Hide
|
C30H33ClN4O5S2
|
1
|
| 1 |
IC50 = 460 nM
|
|
|
|
CP0732546
|
5-Isobutyl-2-(3-methoxyphenyl)-6-(((S)-1-(((R)-tetrahydrofuran-2-yl)methyl)piperidin-3-yl)methyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
|
C27H37N5O3
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0416440
|
3-[(1S)-1-[2,3-dichloro-4-(2-cyclopropylethynyl)phenyl]ethyl]-1-[1-(2,3-dihydro-1H-inden-1-yl)piperidin-4-yl]-1-methylurea
Show/Hide
|
C29H33Cl2N3O
|
1
|
| 1 |
IC50 = 919 nM
|
|
|
|
CP0323172
|
2-chloro-4-ethoxy-N-[[6-[(4-methylpiperazin-1-yl)methyl]-1,3-benzothiazol-2-yl]carbamoyl]-5-morpholin-4-ylbenzamide
Show/Hide
|
C27H33ClN6O4S
|
1
|
| 1 |
IC50 = 960 nM
|
|
|
|
CP0842290
|
2-(3-Methoxyphenyl)-5-methyl-6-(((S)-1-(((R)-tetrahydrofuran-2-yl)methyl)piperidin-3-yl)methyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
|
C24H31N5O3
|
1
|
| 1 |
IC50 = 980 nM
|
|
|
|
CP0154281
|
2-(4-methoxyphenoxy)-1-[2-[[4-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
Show/Hide
|
C26H30N4O4
|
2
|
| 1 |
IC50 = 1070 nM
|
|
|
| 2 |
Ki = 52 nM
|
|
|
|
CP0391974
|
2-(5-methoxypyridin-2-yl)-1-[2-[(1S)-5-pyrimidin-2-yl-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
Show/Hide
|
C28H31N5O2
|
1
|
| 1 |
IC50 = 1096.48 nM
|
|
|
|
CP0450825
|
3-[[2,3-dichloro-4-(2-cyclopropylethynyl)phenyl]methyl]-1-methyl-1-[1-[5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]piperidin-4-yl]urea
Show/Hide
|
C33H35Cl2N5O
|
1
|
| 1 |
IC50 = 1130 nM
|
|
|
|
CP0450823
|
3-[(1S)-1-(2,3-dichloro-4-methoxyphenyl)ethyl]-1-[1-(5-hydroxy-2,3-dihydro-1H-inden-1-yl)piperidin-4-yl]-1-methylurea
Show/Hide
|
C25H31Cl2N3O3
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0549342
|
3-(1,3-benzothiazol-2-yl)-6-(2-chloro-4-ethoxy-5-morpholin-4-ylphenyl)-1H-pyridin-2-one
Show/Hide
|
C24H22ClN3O3S
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0387426
|
1-[1-(5-amino-2,3-dihydro-1H-inden-1-yl)piperidin-4-yl]-3-[(1S)-1-(2,3-dichloro-4-methoxyphenyl)ethyl]-1-methylurea
Show/Hide
|
C25H32Cl2N4O2
|
1
|
| 1 |
IC50 = 1510 nM
|
|
|
|
CP0516429
|
6-(2-chloro-4-ethoxy-5-morpholin-4-ylphenyl)-3-[5-(2-hydroxyacetyl)-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl]-1H-pyridin-2-one
Show/Hide
|
C25H27ClN4O5S
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0450828
|
3-[(1S)-1-[2,3-dichloro-4-(2-trimethylsilylethynyl)phenyl]ethyl]-1-methyl-1-[1-(5-methyl-2,3-dihydro-1H-inden-1-yl)piperidin-4-yl]urea
Show/Hide
|
C30H39Cl2N3OSi
|
1
|
| 1 |
IC50 = 2005 nM
|
|
|
|
CP0547591
|
3-[(1S)-1-(2,3-dichloro-4-cyclopropylphenyl)ethyl]-1-methyl-1-[1-(5-methyl-2,3-dihydro-1H-inden-1-yl)piperidin-4-yl]urea
Show/Hide
|
C28H35Cl2N3O
|
1
|
| 1 |
IC50 = 2367 nM
|
|
|
|
CP0467813
|
3-[(2,3-dichlorophenyl)methyl]-1-methyl-1-[1-[5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]piperidin-4-yl]urea
Show/Hide
|
C28H31Cl2N5O
|
1
|
| 1 |
IC50 = 2700 nM
|
|
|
|
CP0462683
|
1-(2-benzyl-2,7-diazaspiro[3.5]nonan-7-yl)-2-(4-methoxyphenoxy)ethanone
Show/Hide
|
C23H28N2O3
|
1
|
| 1 |
IC50 = 2980 nM
|
|
|
|
CP0965208
|
rac-4-[5-(2-Methylpyridin-3-yl)-6-{[1-(oxetan-3-yl)piperidin-3-yl]methyl}-7-oxo-6,7-dihydro-2H-pyrazolo[4,3-d]pyrimidin-2-yl]benzonitrile
Show/Hide
|
C27H27N7O2
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
|
CP0410661
|
2-chloro-N-[(5-methylsulfonyl-1,3-benzothiazol-2-yl)carbamoyl]benzamide
Show/Hide
|
C16H12ClN3O4S2
|
1
|
| 1 |
IC50 = 4700 nM
|
|
|
|
CP0121389
|
5-(1,3-benzothiazol-2-yl)-2-(2-chloro-4-ethoxy-5-morpholin-4-ylphenyl)-1H-pyrimidin-6-one
Show/Hide
|
C23H21ClN4O3S
|
1
|
| 1 |
IC50 = 5200 nM
|
|
|
|
CP0410660
|
2-chloro-N-[(6-methylsulfonyl-1,3-benzoxazol-2-yl)carbamoyl]benzamide
Show/Hide
|
C16H12ClN3O5S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0339575
|
2-chloro-5-[(2S,6S)-2,6-dimethylmorpholin-4-yl]-4-ethoxy-N-[6-[3-(4-methylpiperazin-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]benzamide
Show/Hide
|
C30H40ClN5O5S2
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0137373
|
2-(2-chloro-4-ethoxy-5-morpholin-4-ylphenyl)-5-[6-(1-methylpiperidin-4-yl)sulfonyl-1,3-benzothiazol-2-yl]-1H-pyrimidin-6-one
Show/Hide
|
C29H32ClN5O5S2
|
1
|
| 1 |
IC50 > 18000 nM
|
|
|
|
CP0571234
|
2-chloro-4-ethoxy-5-[(2R)-2-methylmorpholin-4-yl]-N-[6-[3-(4-methylpiperazin-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]benzamide
Show/Hide
|
C29H38ClN5O5S2
|
1
|
| 1 |
IC50 = 21000 nM
|
|
|
|
CP0368589
|
2-chloro-5-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-4-ethoxy-N-[6-[3-(4-methylpiperazin-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]benzamide
Show/Hide
|
C30H40ClN5O5S2
|
1
|
| 1 |
IC50 = 27000 nM
|
|
|
|
CP0387433
|
2,3-dichloro-4-[(1S)-1-[[methyl-[1-[5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]piperidin-4-yl]carbamoyl]amino]ethyl]benzoic acid
Show/Hide
|
C30H33Cl2N5O3
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0487589
|
2-chloro-4-ethoxy-N-[6-(1-methylpiperidin-4-yl)oxy-1,3-benzothiazol-2-yl]-5-morpholin-4-ylbenzamide
Show/Hide
|
C26H31ClN4O4S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0367161
|
2-chloro-4-ethoxy-N-[6-[(4-methylpiperazin-1-yl)methyl]-1,3-benzothiazol-2-yl]-5-morpholin-4-ylbenzamide
Show/Hide
|
C26H32ClN5O3S
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0367162
|
2-chloro-4-ethoxy-N-[6-[3-(4-methylpiperazin-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]-5-morpholin-4-ylbenzamide
Show/Hide
|
C28H36ClN5O5S2
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0368590
|
N-(1,3-benzothiazol-2-yl)-2-chloro-4-ethoxy-5-morpholin-4-ylbenzamide
Show/Hide
|
C20H20ClN3O3S
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0487588
|
6-(2-chloro-4-ethoxy-5-morpholin-4-ylphenyl)-3-[5-(2-methoxyacetyl)-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl]-1H-pyridin-2-one
Show/Hide
|
C26H29ClN4O5S
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0517571
|
2-chloro-4-ethoxy-N-[6-(1-methylpiperidin-4-yl)sulfonyl-1,3-benzothiazol-2-yl]-5-morpholin-4-ylbenzamide
Show/Hide
|
C26H31ClN4O5S2
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0525468
|
2-chloro-4-ethoxy-N-methyl-N-[[6-[(4-methylpiperazin-1-yl)methyl]-1,3-benzothiazol-2-yl]carbamoyl]-5-morpholin-4-ylbenzamide
Show/Hide
|
C28H35ClN6O4S
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0535089
|
1-(2-chloro-4-ethoxy-5-morpholin-4-ylphenyl)-3-[6-[(4-methylpiperazin-1-yl)methyl]-1,3-benzothiazol-2-yl]urea
Show/Hide
|
C26H33ClN6O3S
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0478394
|
(2R)-4-methyl-N-[(1S,2S)-2-[(1-methylindole-5-carbonyl)amino]-2,3-dihydro-1H-inden-1-yl]-1,4-oxazepane-2-carboxamide
Show/Hide
|
C26H30N4O3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0414309
|
1-[(2-chloro-4-ethoxy-5-morpholin-4-ylphenyl)methyl]-3-[6-[(4-methylpiperazin-1-yl)methyl]-1,3-benzothiazol-2-yl]urea
Show/Hide
|
C27H35ClN6O3S
|
1
|
| 1 |
IC50 > 4970 nM
|
|
|
|
CP0260064
|
(6S,9R,12R)-12-benzyl-6-[(2S)-butan-2-yl]-8,9-dimethyl-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-triene-7,10,13-trione
Show/Hide
|
C30H42N4O4
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0260068
|
(6S,9R,12R)-6-cyclopropyl-12-[(4-fluorophenyl)methyl]-8,9-dimethyl-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-triene-7,10,13-trione
Show/Hide
|
C29H37FN4O4
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0332150
|
(6S,9R,12R)-6-cyclopropyl-12-[(2-fluorophenyl)methyl]-8,9-dimethyl-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-triene-7,10,13-trione
Show/Hide
|
C29H37FN4O4
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0851619
|
(5S,11S)-11-(3-chlorobenzyl)-5-isobutyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
|
C32H41ClN4O4
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0851639
|
(5S,8R,11R)-11-benzyl-5-sec-butyl-7,8-dimethyl-4,5,7,8,10,11,13,14-octahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
|
C30H40N4O4
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0851656
|
(5S,8R,11R)-5-sec-butyl-7,8-dimethyl-11-(naphthalen-2-ylmethyl)-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
|
C34H44N4O4
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0851657
|
(5S,8R,11R)-11-benzyl-5-tert-butyl-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
|
C30H42N4O4
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0864332
|
(5S,8R,11R)-11-(4-chlorobenzyl)-5-cyclopropyl-7,8-dimethyl-4,5,7,8,10,11,13,14-octahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
|
C29H35ClN4O4
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0864414
|
(5S,8R,11R)-5-cyclopropyl-7,8-dimethyl-11-(3,4,5-trifluorobenzyl)-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
|
C29H35F3N4O4
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0864465
|
(2S,5S,11S)-5-sec-butyl-11-(3-chlorobenzyl)-2-methyl-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
|
C33H45ClN4O4
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0864940
|
(2R,5S,11S)-5-sec-butyl-11-(3-chlorobenzyl)-2-methyl-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
|
C33H45ClN4O4
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0864951
|
(5S,8R,11R)-5-cyclopropyl-11-(2,4-dichlorobenzyl)-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
|
C29H36Cl2N4O4
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0864952
|
(1aS,5S,11R,19bS)-11-sec-butyl-5-(3-chlorobenzyl)-2,3,5,6,11,12,13,14-octahydro-1H-spiro[benzo[q]cyclopropa[o][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-4,7,10(1aH,9H,19bH)-trione
Show/Hide
|
C33H43ClN4O4
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0867097
|
CHEMBL3955179
Show/Hide
|
C32H39ClN4O4
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0875141
|
(5S,8R,11R)-5-sec-butyl-11-(4-fluorobenzyl)-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
|
C30H41FN4O4
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0875579
|
(5S,8R,11S)-11-benzyl-5-isopropyl-7,8-dimethyl-4,5,7,8,10,11,13,14-octahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
|
C29H38N4O4
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0883289
|
(5S,8R,11R)-5-sec-butyl-11-(3-chlorobenzyl)-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
|
C30H41ClN4O4
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0883418
|
(5S,8R,11R)-5-sec-butyl-11-(2-chlorobenzyl)-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
|
C30H41ClN4O4
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0883419
|
(5S,8R,11R)-5-sec-butyl-11-(4-methoxybenzyl)-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
|
C31H44N4O5
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0883420
|
(5S,8R,11R)-5-sec-butyl-7,8-dimethyl-11-(naphthalen-1-ylmethyl)-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C34H44N4O4
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1
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| 1 |
Ki = 0.1 nM
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CP0894009
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(5S,8R,11R)-11-benzyl-7,8-dimethyl-5-propyl-4,5,7,8,10,11,13,14-octahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C29H38N4O4
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1
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| 1 |
Ki = 0.1 nM
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CP0899599
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(5S,8R,11R)-5-cyclopropyl-7,8-dimethyl-11-(perfluorobenzyl)-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C29H33F5N4O4
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1
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| 1 |
Ki = 0.1 nM
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CP0902767
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(5S,8R,11R)-11-(4-chlorobenzyl)-5-cyclopropyl-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C29H37ClN4O4
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1
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| 1 |
Ki = 0.1 nM
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CP0903663
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(5S,8R,11R)-5-cyclopropyl-11-(4-fluorobenzyl)-7,8-dimethyl-4,5,7,8,10,11,13,14-octahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C29H35FN4O4
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1
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| 1 |
Ki = 0.1 nM
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CP0911460
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(5S,8R,11R)-5-cyclopropyl-11-(4-iodobenzyl)-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C29H37IN4O4
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1
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| 1 |
Ki = 0.1 nM
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CP0913566
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(5S,8R,11R)-5-cyclopropyl-11-(3,4-dichlorobenzyl)-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C29H36Cl2N4O4
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1
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| 1 |
Ki = 0.1 nM
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CP0913576
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(5S,11S)-11-(2-chlorobenzyl)-5-isobutyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C32H41ClN4O4
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1
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| 1 |
Ki = 0.1 nM
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CP0915634
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(2S)-5-sec-butyl-11-(3-chlorobenzyl)-2-methyl-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C33H45ClN4O4
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1
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| 1 |
Ki = 0.1 nM
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CP0919533
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(5S,8R,11R)-11-(4-bromobenzyl)-5-cyclopropyl-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C29H37BrN4O4
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1
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| 1 |
Ki = 0.1 nM
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CP0949434
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(5S,11S)-5-sec-butyl-11-(3,4-dichlorobenzyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C32H40Cl2N4O4
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1
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| 1 |
Ki = 0.1 nM
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CP0910508
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(R)-N-[2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethyl]-2-(2-cyanoacetamido)acetamide
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C33H33N7O3
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1
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| 1 |
Ki = 0.45 nM
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CP0510437
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2-(5-methoxypyridin-2-yl)-1-[2-[(1R)-5-(triazol-2-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
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C26H30N6O2
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1
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| 1 |
Ki = 3.311 nM
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CP0946596
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(R)-N-[2-(2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethylamino)-2-oxoethyl]-2-cyano-2-methylpropanamide
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C35H37N7O3
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1
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| 1 |
Ki = 3.4 nM
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CP0426763
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2-(5-methoxypyridin-2-yl)-1-[2-[(1R)-5-(1,3-thiazol-2-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
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C27H30N4O2S
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1
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| 1 |
Ki = 3.981 nM
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CP0398733
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5-methoxy-2-[2-[2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]-2-oxoethoxy]benzonitrile
Show/Hide
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C31H33N5O3
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1
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| 1 |
Ki = 4 nM
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CP0954377
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(R)-N-[2-(2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethylamino)-2-oxoethyl]acrylamide
Show/Hide
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C33H34N6O3
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1
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| 1 |
Ki = 4 nM
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CP0389621
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2-(2-methylimidazo[2,1-b][1,3]thiazol-6-yl)-1-[2-[(1R)-5-pyrimidin-2-yl-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
Show/Hide
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C28H30N6OS
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2
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| 1 |
Ki = 4.571 nM
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| 2 |
Ki = 6.607 nM
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CP0956828
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(R)-N-[2-(2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethylamino)-2-oxoethyl]-6-cyanonicotinamide
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C37H34N8O3
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1
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| 1 |
Ki = 6.3 nM
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CP0048654
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2-(4-methoxyphenyl)-1-[2-[(1R)-5-pyrimidin-2-yl-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
Show/Hide
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C29H32N4O2
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3
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| 1 |
Ki = 6.31 nM
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| 2 |
Ki = 6.9 nM
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| 3 |
Ki = 17.38 nM
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CP0280053
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2-(5-cyclopropylpyridin-2-yl)-1-[2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
Show/Hide
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C31H35N5O
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1
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| 1 |
Ki = 6.4 nM
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CP0048653
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2-(2-methylimidazo[2,1-b][1,3]thiazol-6-yl)-1-[2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
Show/Hide
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C29H32N6OS
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1
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| 1 |
Ki = 6.607 nM
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CP0404035
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2-(4-methoxyphenyl)-1-[2-[(1R)-5-(triazol-2-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
Show/Hide
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C27H31N5O2
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1
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| 1 |
Ki = 7.413 nM
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CP0379658
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2-(5-methoxypyridin-2-yl)-1-[2-[(1R)-5-(5-methylpyrimidin-2-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
Show/Hide
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C29H33N5O2
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2
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| 1 |
Ki = 9.12 nM
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| 2 |
Ki = 85.11 nM
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CP0395745
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1-[2-[(1R)-5-(5-ethylpyrimidin-2-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]-2-(5-methoxypyridin-2-yl)ethanone
Show/Hide
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C30H35N5O2
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1
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| 1 |
Ki = 9.12 nM
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CP0053559
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5-methoxy-2-[2-[2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]-2-oxoethyl]benzamide
Show/Hide
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C31H35N5O3
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1
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| 1 |
Ki = 9.2 nM
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CP0151997
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(6S,9R,12R)-6-[(2S)-butan-2-yl]-8,9-dimethyl-12-(2-phenylethyl)-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-triene-7,10,13-trione
Show/Hide
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C31H44N4O4
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1
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| 1 |
Ki = 10 nM
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CP0151998
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(6S,9R,12R)-6-cyclopropyl-12-[(3-fluorophenyl)methyl]-8,9-dimethyl-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-triene-7,10,13-trione
Show/Hide
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C29H37FN4O4
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1
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| 1 |
Ki = 10 nM
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CP0213743
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(6S,9R,12R)-6-cyclopropyl-20-fluoro-12-[(4-fluorophenyl)methyl]-8,9-dimethyl-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(18),19,21-triene-7,10,13-trione
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C29H36F2N4O4
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1
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| 1 |
Ki = 10 nM
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CP0260123
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(6S,9R,12R)-12-benzyl-8,9-dimethyl-6-(2-methylpropyl)-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-triene-7,10,13-trione
Show/Hide
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C30H42N4O4
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1
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| 1 |
Ki = 10 nM
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CP0274269
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(7R,10R,13S)-7-benzyl-13-[(2S)-butan-2-yl]-10,11-dimethyl-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-triene-6,9,12-trione
Show/Hide
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C31H44N4O3
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1
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| 1 |
Ki = 10 nM
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CP0848575
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(5S,8R,11R)-11-(4-fluorobenzyl)-5-(1-methoxyethyl)-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C29H39FN4O5
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1
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| 1 |
Ki = 10 nM
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CP0848576
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(5S,11S)-5-sec-butyl-11-(3-chlorobenzyl)-15-methyl-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C33H45ClN4O4
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1
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| 1 |
Ki = 10 nM
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CP0851210
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(5S,11S)-5-isobutyl-11-(4-methoxybenzyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C33H44N4O5
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1
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| 1 |
Ki = 10 nM
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CP0851638
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(5S,8R,11R,Z)-5-cyclopropyl-11-(4-fluorobenzyl)-7,8-dimethyl-4,5,7,8,10,11,13,14-octahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C29H35FN4O4
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1
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| 1 |
Ki = 10 nM
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CP0851641
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(5S,11S)-11-benzyl-5-isobutyl-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C32H44N4O4
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1
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| 1 |
Ki = 10 nM
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CP0858819
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(5S,8R,11R)-5-sec-butyl-11-isobutyl-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C28H46N4O4
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1
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| 1 |
Ki = 10 nM
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CP0864461
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(5S,11S)-5-sec-butyl-11-(4-chlorobenzyl)-2,3,4,4',5,5',10,11,13,14-decahydro-2'H-spiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,3'-furan]-6,9,12(7H)-trione
Show/Hide
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C31H39ClN4O5
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1
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| 1 |
Ki = 10 nM
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CP0864462
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(5S,11R)-5-sec-butyl-11-(3-chlorobenzyl)-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C32H43ClN4O4
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1
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| 1 |
Ki = 10 nM
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CP0864937
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(5S,8R,11R)-5-cyclopropyl-7,8-dimethyl-11-(thiophen-3-ylmethyl)-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C27H36N4O4S
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1
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| 1 |
Ki = 10 nM
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CP0864938
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(5S,11S)-5-sec-butyl-11-(3-methoxybenzyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C33H44N4O5
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1
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| 1 |
Ki = 10 nM
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CP0864947
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(5S,11S)-11-benzyl-5-isobutyl-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopropane]-6,9,12(7H)-trione
Show/Hide
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C30H40N4O4
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1
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| 1 |
Ki = 10 nM
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CP0864948
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(5S,11S)-11-(4-chlorobenzyl)-5-isobutyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C32H41ClN4O4
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1
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| 1 |
Ki = 10 nM
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CP0867087
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(5S,8R,11R)-11-benzyl-5-((R)-1-methoxyethyl)-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C29H40N4O5
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1
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| 1 |
Ki = 10 nM
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CP0867091
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(5S,8R,11R)-5-sec-butyl-7,8-dimethyl-11-(pyridin-3-ylmethyl)-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C29H41N5O4
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1
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| 1 |
Ki = 10 nM
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CP0867096
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(1aS,19bS)-11-cyclopropyl-5-(4-fluorobenzyl)-8,9-dimethyl-1,1a,2,3,5,6,8,9,11,12,13,14-dodecahydrobenzo[q]cyclopropa[o][1,4,7,10,13]oxatetraazacyclooctadecine-4,7,10(19bH)-trione
Show/Hide
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C30H37FN4O4
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1
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| 1 |
Ki = 10 nM
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CP0867098
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(S)-11-(3-chlorobenzyl)-5,5-dimethyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C30H37ClN4O4
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1
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| 1 |
Ki = 10 nM
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CP0869399
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(5S,11S)-11-benzyl-5-propyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C31H40N4O4
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1
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| 1 |
Ki = 10 nM
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CP0869404
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(5S,11S)-5-sec-butyl-11-(3-fluorobenzyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C32H41FN4O4
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1
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| 1 |
Ki = 10 nM
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CP0869405
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5-sec-butyl-11-(4-chlorobenzyl)-2,3,4,4',5,5',10,11,13,14-decahydro-2'H-spiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,3'-furan]-6,9,12(7H)-trione
Show/Hide
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C31H39ClN4O5
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1
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| 1 |
Ki = 10 nM
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CP0869427
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N-((5S,8R,11R)-5-cyclopropyl-11-(4-fluorobenzyl)-7,8-dimethyl-6,9,12-trioxo-3,4,5,6,7,8,9,10,11,12,13,14,15,16-tetradecahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecin-18-yl)methanesulfonamide
Show/Hide
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C30H40FN5O6S
|
1
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| 1 |
Ki = 10 nM
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CP0871225
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(5S,11S)-11-(4-fluorobenzyl)-5-isobutyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C32H41FN4O4
|
1
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| 1 |
Ki = 10 nM
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CP0873708
|
(5S,8R,11R)-11-benzhydryl-5-sec-butyl-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C36H46N4O4
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1
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| 1 |
Ki = 10 nM
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CP0875139
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(5S,8R,11R)-11-benzyl-5-sec-butyl-8-ethyl-7-methyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C31H44N4O4
|
1
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| 1 |
Ki = 10 nM
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CP0875140
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(5S,8R,11R)-5-sec-butyl-7,8-dimethyl-11-(thiophen-2-ylmethyl)-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C28H40N4O4S
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1
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| 1 |
Ki = 10 nM
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CP0875145
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(4aS,7R,10R)-10-benzyl-6,7-dimethyl-2,3,4,4a,6,7,9,10,12,13,14,15,21,22-tetradecahydrobenzo[q]pyrido[1,2-d][1,4,7,10,13]oxatetraazacyclooctadecine-5,8,11(1H)-trione
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C30H40N4O4
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1
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| 1 |
Ki = 10 nM
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CP0875147
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(5S,8R,11R)-11-((1H-indol-3-yl)methyl)-5-cyclopropyl-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C31H39N5O4
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1
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| 1 |
Ki = 10 nM
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CP0875148
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(5S,11S)-11-(3-bromobenzyl)-5-sec-butyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C32H41BrN4O4
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1
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| 1 |
Ki = 10 nM
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CP0875149
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(5S,11S)-5-sec-butyl-11-(3-(trifluoromethyl)benzyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C33H41F3N4O4
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1
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| 1 |
Ki = 10 nM
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CP0875150
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(7R,10R,13S)-13-cyclopropyl-7-[(4-fluorophenyl)methyl]-10,11-dimethyl-17-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(18),19,21-trien-2-yne-6,9,12-trione
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C29H33FN4O4
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1
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| 1 |
Ki = 10 nM
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CP0875154
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(5S,8R,11R)-11-(3-tert-butyl-4-hydroxybenzyl)-5-cyclopropyl-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C33H46N4O5
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1
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| 1 |
Ki = 10 nM
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CP0875157
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(5S,8R,11R)-11-benzyl-5-sec-butyl-7-ethyl-8-methyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C31H44N4O4
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1
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| 1 |
Ki = 10 nM
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CP0875159
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(5S,11S)-5-isobutyl-11-(naphthalen-1-ylmethyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C36H44N4O4
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1
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| 1 |
Ki = 10 nM
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CP0875576
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(8R,11R)-11-(3-chlorobenzyl)-7,8-dimethyl-3,4,7,8,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-5,1'-cyclopentane]-6,9,12(2H)-trione
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C30H37ClN4O4
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1
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| 1 |
Ki = 10 nM
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CP0875584
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(5S,11S)-5-isobutyl-11-(naphthalen-2-ylmethyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C36H44N4O4
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1
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| 1 |
Ki = 10 nM
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CP0875588
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(7S,13S)-7-[(3-chlorophenyl)methyl]-13-sec-butyl-spiro[17-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(18),19,21-trien-2-yne-10,1'-cyclopentane]-6,9,12-trione
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C32H39ClN4O4
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1
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| 1 |
Ki = 10 nM
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CP0883269
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(1aS,5S,8S,11R,19bS)-11-cyclopropyl-5-(4-fluorobenzyl)-8,9-dimethyl-1,1a,2,3,5,6,8,9,11,12,13,14-dodecahydrobenzo[q]cyclopropa[o][1,4,7,10,13]oxatetraazacyclooctadecine-4,7,10(19bH)-trione
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C30H37FN4O4
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1
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| 1 |
Ki = 10 nM
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CP0883270
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(5S,11S)-5-sec-butyl-11-(3-chlorobenzyl)-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,3'-pyrrolidine]-6,9,12(7H)-trione
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C31H42ClN5O4
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1
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| 1 |
Ki = 10 nM
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CP0883415
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(5S,11S)-11-benzyl-5-isobutyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C32H42N4O4
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1
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| 1 |
Ki = 10 nM
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CP0883416
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(5S,11S)-11-(4-chlorobenzyl)-5-cyclopropyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C31H37ClN4O4
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1
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| 1 |
Ki = 10 nM
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CP0888237
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(5S,8R,11R)-11-benzyl-5-ethyl-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C28H38N4O4
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1
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| 1 |
Ki = 10 nM
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CP0888297
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5-sec-butyl-11-(3-chlorobenzyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C33H43ClN4O3
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1
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| 1 |
Ki = 10 nM
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CP0893998
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(5S,8R,11R)-5-sec-butyl-7,8-dimethyl-11-(pyridin-2-ylmethyl)-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C29H41N5O4
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1
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| 1 |
Ki = 10 nM
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CP0894008
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(S)-11-(3-chlorobenzyl)-8,8-dimethyl-3,4,7,8,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-5,1'-cyclopentane]-6,9,12(2H)-trione
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C30H37ClN4O4
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1
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| 1 |
Ki = 10 nM
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CP0894705
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12-sec-butyl-6-(4-fluorobenzyl)-9,10-dimethyl-3,4,6,7,9,10,13,14,15,16-decahydrobenzo[n][1,4,7,10]tetraazacyclooctadecine-5,8,11(12H)-trione
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C31H41FN4O3
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1
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| 1 |
Ki = 10 nM
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CP0895642
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(5S,11S)-11-benzyl-5-isopropyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C31H40N4O4
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1
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| 1 |
Ki = 10 nM
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CP0895644
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(3S,6R,9R)-9-benzyl-3-sec-butyl-5,6-dimethyl-2,3,5,6,8,9,12,13-octahydrobenzo[l][1,4,7,10]tetraazacyclooctadecine-4,7,10(1H,11H,16H)-trione
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C31H42N4O3
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1
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| 1 |
Ki = 10 nM
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CP0899602
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(4S,7R,10R)-10-Benzyl-4-cyclopropyl-6,7-dimethyl-22-oxa-3,6,9,12-tetraaza-tricyclo[14.5.3.0(19,23)]tetracosa-16(24),17,19(23)-triene-5,8,11-trione
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C31H40N4O4
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1
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| 1 |
Ki = 10 nM
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CP0899603
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(5S,8R,11R)-5-sec-butyl-11-(4-hydroxybenzyl)-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C30H42N4O5
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1
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| 1 |
Ki = 10 nM
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CP0901794
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(5S,8R,11R)-11-(biphenyl-4-ylmethyl)-5-sec-butyl-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C36H46N4O4
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1
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| 1 |
Ki = 10 nM
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CP0902543
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(5S,8R,11R)-11-(4-fluorobenzyl)-7,8-dimethyl-5-(2-(methylthio)ethyl)-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C29H39FN4O4S
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1
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| 1 |
Ki = 10 nM
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CP0902763
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(3S,6R,9R)-9-benzyl-3-sec-butyl-5,6-dimethyl-2,3,5,6,8,9,11,12,13,14,15,16-dodecahydrobenzo[1][1,4,7,10]tetraazacyclooctadecine-4,7,10(1H)-trione
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C31H44N4O3
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1
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| 1 |
Ki = 10 nM
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CP0902765
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11-benzyl-5-sec-butyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C32H42N4O4
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1
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| 1 |
Ki = 10 nM
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CP0902768
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(5S,11S)-11-(3-chlorobenzyl)-5-(4-hydroxybenzyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C35H39ClN4O5
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1
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| 1 |
Ki = 10 nM
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CP0903660
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(6R,9R,12S)-12-sec-butyl-6-(4-fluorobenzyl)-9,10-dimethyl-3,4,6,7,9,10,13,14,15,16-decahydrobenzo[n][1,4,7,10]tetraazacyclooctadecine-5,8,11(12H)-trione
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C31H41FN4O3
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1
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| 1 |
Ki = 10 nM
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CP0903692
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(5S,11S)-5-sec-butyl-11-(3-chlorobenzyl)-18-fluoro-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C32H42ClFN4O4
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1
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| 1 |
Ki = 10 nM
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CP0906041
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(2S,5S,8R,11R)-11-benzyl-5-sec-butyl-2,7,8-trimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C31H44N4O4
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1
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| 1 |
Ki = 10 nM
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CP0906045
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(5S,11R)-11-benzyl-7-methyl-5-propyl-4,5,7,8,10,11,13,14-octahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C28H36N4O4
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1
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| 1 |
Ki = 10 nM
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CP0911194
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(6R,9R,12S)-6-benzyl-12-sec-butyl-9,10-dimethyl-3,4,6,7,9,10,13,14,15,16-decahydrobenzo[n][1,4,7,10]tetraazacyclooctadecine-5,8,11(12H)-trione
Show/Hide
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C31H42N4O3
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1
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| 1 |
Ki = 10 nM
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CP0911457
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(5S,8R,11R)-5-sec-butyl-7,8-dimethyl-11-(pyridin-4-ylmethyl)-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C29H41N5O4
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1
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| 1 |
Ki = 10 nM
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CP0911461
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4-(((5S,8R,11R)-5-cyclopropyl-7,8-dimethyl-6,9,12-trioxo-3,4,5,6,7,8,9,10,11,12,13,14,15,16-tetradecahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecin-11-yl)methyl)benzonitrile
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C30H37N5O4
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1
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| 1 |
Ki = 10 nM
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CP0911463
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(5S,11S)-5-sec-butyl-11-(3-chlorobenzyl)-2,3,4,5,10,11,13,14-octahydro-1H-spiro[benzo[n][1,4,7,10]tetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C33H43ClN4O3
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1
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| 1 |
Ki = 10 nM
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CP0911465
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5-sec-butyl-11-(3-chlorobenzyl)-2-methyl-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C33H45ClN4O4
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1
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| 1 |
Ki = 10 nM
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CP0911468
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(5S,11S,E)-5-sec-butyl-11-(3-chlorobenzyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C32H41ClN4O4
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1
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| 1 |
Ki = 10 nM
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CP0913567
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(5S,8R,11R)-5-cyclopropyl-11-(3,5-difluorobenzyl)-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C29H36F2N4O4
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1
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| 1 |
Ki = 10 nM
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CP0913577
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6-benzyl-12-sec-butyl-9,10-dimethyl-3,4,6,7,9,10,13,14,15,16-decahydrobenzo[n][1,4,7,10]tetraazacyclooctadecine-5,8,11(12H)-trione
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C31H42N4O3
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1
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| 1 |
Ki = 10 nM
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CP0913578
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(5S,11R)-11-benzyl-5-isobutyl-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C32H44N4O4
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1
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| 1 |
Ki = 10 nM
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CP0914437
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(5S,8R,11R)-5-cyclopropyl-11-(4-fluorobenzyl)-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-pyrido[2,3-q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C28H36FN5O4
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1
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| 1 |
Ki = 10 nM
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CP0915635
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(2R,5S,8R,11R)-11-benzyl-5-cyclopropyl-19-fluoro-2,7,8-trimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C30H39FN4O4
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1
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| 1 |
Ki = 10 nM
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CP0919532
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5-cyclopropyl-11-(4-fluorobenzyl)-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-pyrido[2,3-q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C28H36FN5O4
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1
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| 1 |
Ki = 10 nM
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CP0919534
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(5S,11S)-11-(4-chlorobenzyl)-5-(thiophen-3-ylmethyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C33H37ClN4O4S
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1
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| 1 |
Ki = 10 nM
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CP0919547
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N-((S)-1-amino-3-(3-chlorophenyl)-1-oxopropan-2-yl)-1-((2S,3R)-3-methyl-2-(3-(2-pentylphenyl)propylamino)pentanamido)cyclopentanecarboxamide
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C34H47ClN4O3
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1
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| 1 |
Ki = 10 nM
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CP0930894
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CHEMBL3932434
Show/Hide
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C32H40N4O4
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1
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| 1 |
Ki = 10 nM
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CP0932748
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3-(((5S,11S)-5-sec-butyl-6,9,12-trioxo-2,3,4,5,6,7,9,10,11,12,13,14-dodecahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-11-yl)methyl)benzonitrile
Show/Hide
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C33H41N5O4
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1
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| 1 |
Ki = 10 nM
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CP0932779
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(5S,11S)-11-benzyl-5-sec-butyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C32H42N4O4
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1
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| 1 |
Ki = 10 nM
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CP0932782
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(5S,8S,11R)-11-benzyl-5-sec-butyl-8-ethyl-7,10-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C31H42N4O4
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1
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| 1 |
Ki = 10 nM
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CP0933076
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(8R,11S)-11-(3-chlorobenzyl)-8-methyl-3,4,7,8,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-5,1'-cyclopentane]-6,9,12(2H)-trione
Show/Hide
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C29H35ClN4O4
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1
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| 1 |
Ki = 10 nM
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CP0945375
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(5S,11S)-11-benzyl-5-ethyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C30H38N4O4
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1
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| 1 |
Ki = 10 nM
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CP0952678
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(5S,11S)-11-benzyl-5-isopropyl-2,3,4,4',5,5',10,11,13,14-decahydro-2'H-spiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,3'-furan]-6,9,12(7H)-trione
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C30H38N4O5
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1
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| 1 |
Ki = 10 nM
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CP0954595
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(5S,8R,11R)-5-cyclopropyl-11-(3,4-difluorobenzyl)-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C29H36F2N4O4
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1
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| 1 |
Ki = 10 nM
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CP0959891
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(5S,11S)-5-sec-butyl-11-(3,5-difluorobenzyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C32H40F2N4O4
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1
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| 1 |
Ki = 10 nM
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CP0961291
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(5S,8R,11R)-18-chloro-5-cyclopropyl-11-(4-fluorobenzyl)-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C29H36ClFN4O4
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1
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| 1 |
Ki = 10 nM
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CP0963860
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(5S,11S)-5-sec-butyl-11-(3,4-difluorobenzyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C32H40F2N4O4
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1
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| 1 |
Ki = 10 nM
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CP0911628
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(R)-N-[2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethyl]-2-acetamidoacetamide
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C32H34N6O3
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1
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| 1 |
Ki = 10 nM
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CP0395744
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2-(5-methylpyridin-2-yl)-1-[2-[(1R)-5-(triazol-2-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
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C26H30N6O
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1
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| 1 |
Ki = 10.47 nM
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CP0556202
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5-[(1R)-1-[7-[2-(2-methylimidazo[2,1-b][1,3]thiazol-6-yl)acetyl]-2,7-diazaspiro[3.5]nonan-2-yl]-2,3-dihydro-1H-inden-5-yl]pyridine-2-carboxamide
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C30H32N6O2S
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1
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| 1 |
Ki = 10.47 nM
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CP0902843
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(R)-N-[2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethyl]-2-formamidoacetamide
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C31H32N6O3
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1
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| 1 |
Ki = 12 nM
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CP0280055
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2-(5-methoxypyridin-2-yl)-1-[2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
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C29H33N5O2
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3
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| 1 |
Ki = 12.88 nM
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| 2 |
Ki = 14 nM
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| 3 |
Ki = 16.98 nM
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CP0498110
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5-methoxy-2-[2-[2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]-2-oxoethyl]benzonitrile
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C31H33N5O2
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1
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| 1 |
Ki = 13 nM
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CP0329376
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(6S,9S,12R)-12-benzyl-8,9-dimethyl-6-propyl-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-triene-7,10,13-trione
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C29H40N4O4
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1
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| 1 |
Ki = 13 nM
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CP0910878
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(R,E)-2-[2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethylamino]-2-oxoethyl 2-cyano-3-(4-methoxyphenyl)acrylate
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C41H38N6O5
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1
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| 1 |
Ki = 13 nM
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CP0515292
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2-(5-ethylpyridin-2-yl)-1-[2-[(1R)-5-pyrimidin-2-yl-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
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C29H33N5O
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1
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| 1 |
Ki = 15.49 nM
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CP0377650
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2-(5-methoxypyridin-2-yl)-1-[2-[(1R)-5-(4-methylpyrimidin-2-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
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C29H33N5O2
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2
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| 1 |
Ki = 15.49 nM
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| 2 |
Ki = 50.12 nM
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CP0385590
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2-(5-ethylpyridin-2-yl)-1-[2-[(1R)-5-(triazol-2-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
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C27H32N6O
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1
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| 1 |
Ki = 16.22 nM
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CP0386570
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5-methoxy-N-methyl-2-[2-[2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]-2-oxoethyl]benzamide
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C32H37N5O3
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1
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| 1 |
Ki = 20 nM
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CP0418550
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2-(5-methoxypyridin-2-yl)-1-[2-[(1R)-5-pyrimidin-2-yl-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
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C28H31N5O2
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2
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| 1 |
Ki = 25.12 nM
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| 2 |
Ki = 29.51 nM
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CP0432993
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2-(5-methylpyridin-2-yl)-1-[2-[(1R)-5-pyrimidin-2-yl-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
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C28H31N5O
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1
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| 1 |
Ki = 27.54 nM
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CP0398197
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N-[5-methoxy-2-[2-[2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]-2-oxoethyl]phenyl]acetamide
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C32H37N5O3
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1
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| 1 |
Ki = 28 nM
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CP0911597
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(R)-N-[2-(2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethylamino)-2-oxoethyl]-4-cyanotetrahydro-2H-pyran-4-carboxamide
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C37H39N7O4
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1
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| 1 |
Ki = 28 nM
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CP0910879
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(R,E)-N-[2-(1-(5-(2-(1H-Indol-3-yl)ethyl)-4-(4-methoxybenzyl)-4H-1,2,4-triazol-3-yl)-2-(1H-Indol-3-yl)ethylamino)-2-oxoethyl]-2-cyano-3-(4-hydroxyphenyl)acrylamide
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C42H38N8O4
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1
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| 1 |
Ki = 30 nM
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CP0385963
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2-amino-N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphenyl)methyl]-5-(2-phenylethyl)-4H-1,2,4-triazol-3-yl}ethyl]acetamide
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C30H32N6O2
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1
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| 1 |
Ki = 43 nM
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CP0425920
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2-(5-methylpyridin-2-yl)-1-[2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
Show/Hide
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C29H33N5O
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1
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| 1 |
Ki = 49 nM
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CP0871675
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(R,E)-N-[2-(2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethylamino)-2-oxoethyl]-3-(4-fluorophenyl)acrylamide
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C39H37FN6O3
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1
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| 1 |
Ki = 56 nM
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CP0864953
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(5S,11R)-11-benzyl-5-butyl-7-methyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C29H40N4O4
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1
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| 1 |
Ki = 67 nM
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CP0395652
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2-(5-methoxypyridin-2-yl)-1-[2-[(1R)-5-pyrimidin-4-yl-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
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C28H31N5O2
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1
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| 1 |
Ki = 69.18 nM
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CP0954717
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(R)-N-[2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethyl]-2-(methylamino)acetamide
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C31H34N6O2
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1
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| 1 |
Ki = 96 nM
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CP0155470
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(6S,12S)-12-benzyl-8-methyl-6-propyl-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-triene-7,10,13-trione
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C28H38N4O4
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1
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| 1 |
Ki = 100 nM
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CP0238558
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(6R,9R,12S)-6-benzyl-12-[(2S)-butan-2-yl]-9,10-dimethyl-4,7,10,13-tetrazabicyclo[15.4.0]henicosa-1(21),17,19-triene-5,8,11-trione
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C30H42N4O3
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1
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| 1 |
Ki = 100 nM
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CP0260065
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(6S,9R,12R)-12-benzyl-9-methyl-6-propyl-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-triene-7,10,13-trione
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C28H38N4O4
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1
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| 1 |
Ki = 100 nM
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CP0274331
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(3R,6R,9S)-3-benzyl-9-[(2S)-butan-2-yl]-6,7-dimethyl-1,4,7,10-tetrazacyclooctadecane-2,5,8-trione
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C27H44N4O3
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1
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| 1 |
Ki = 100 nM
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CP0284750
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(6S,12R)-6,12-dibenzyl-8-methyl-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-triene-7,10,13-trione
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C32H38N4O4
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1
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| 1 |
Ki = 100 nM
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CP0284751
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(6S,12R)-12-butyl-8-methyl-6-propyl-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-triene-7,10,13-trione
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C25H40N4O4
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1
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| 1 |
Ki = 100 nM
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CP0413131
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(6S,9S,12R)-12-benzyl-6-[(2S)-butan-2-yl]-9-(hydroxymethyl)-8-methyl-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-triene-7,10,13-trione
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C30H42N4O5
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1
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| 1 |
Ki = 100 nM
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CP0851208
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(5S,11S)-11-benzyl-5-isopropyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclohexane]-6,9,12(7H)-trione
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C32H42N4O4
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1
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| 1 |
Ki = 100 nM
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CP0851211
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CHEMBL3961696
Show/Hide
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C29H42N4O4
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1
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| 1 |
Ki = 100 nM
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CP0851213
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(5S,8R,11R)-5-sec-butyl-7,8-dimethyl-11-propyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C26H42N4O4
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1
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| 1 |
Ki = 100 nM
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CP0851637
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(5R,8R,11S)-5-benzyl-11-sec-butyl-8,9-dimethyl-2,3,5,6,8,9,11,12,13,14,15,16-dodecahydrobenzo[m][1,4,7,10]tetraazacyclooctadecine-4,7,10(1H)-trione
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C31H44N4O3
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1
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| 1 |
Ki = 100 nM
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CP0858820
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(4S,7R,10R)-10-benzyl-4-sec-butyl-6,7-dimethyl-3,4,6,7,9,10,12,13,14,15-decahydro-1H-benzo[m][1,4,7,10]tetraazacycloheptadecine-5,8,11(2H)-trione
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C30H42N4O3
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1
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| 1 |
Ki = 100 nM
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CP0863069
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(5S,8R,11R)-5-cyclopropyl-11-(4-fluorobenzyl)-7,8,16-trimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C30H39FN4O4
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1
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| 1 |
Ki = 100 nM
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CP0864331
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10-benzyl-4-sec-butyl-6,7-dimethyl-1,2,3,4,6,7,9,10,13,14,15,16-dodecahydrobenzo[m][1,4,7,10]tetraazacyclooctadecine-5,8,11(12H)-trione
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C31H44N4O3
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1
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| 1 |
Ki = 100 nM
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CP0864408
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(5S,11R)-11-((1H-indol-3-yl)methyl)-7-methyl-5-propyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C30H39N5O4
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1
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| 1 |
Ki = 100 nM
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CP0864410
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(5S,11S)-11-(biphenyl-4-ylmethyl)-5-isobutyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C38H46N4O4
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1
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| 1 |
Ki = 100 nM
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CP0864413
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(5S,11S)-5-sec-butyl-11-(3-chlorobenzyl)-2,3,4,5,10,11,14,15-octahydrospiro[benzo[n][1,4,7,10]tetraazacyclononadecine-8,1'-cyclopentane]-6,9,12(1H,7H,13H)-trione
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C34H45ClN4O3
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1
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| 1 |
Ki = 100 nM
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CP0864463
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(5S,8R,11R)-5-cyclopropyl-11-(4-fluorobenzyl)-7,8,15-trimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C30H39FN4O4
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1
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| 1 |
Ki = 100 nM
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CP0864464
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(5S,11S)-5-sec-butyl-11-(3-chlorobenzyl)-7,16-dimethyl-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C33H45ClN4O4
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1
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| 1 |
Ki = 100 nM
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CP0864933
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(5S,11S)-11-benzyl-5-(3-chlorobenzyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C35H39ClN4O4
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1
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| 1 |
Ki = 100 nM
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CP0864936
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(2R,3S,18S)-2-Benzyl-18-sec-butyl-14-oxa-1,4,17-triaza-tricyclo[18.2.1.0(8,13)]tricosa-8,10,12-triene-3,19,23-trione
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C30H39N3O4
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1
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| 1 |
Ki = 100 nM
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CP0864939
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(5S,8R,11R)-5-(2-aminoethyl)-11-(4-fluorobenzyl)-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C28H38FN5O4
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1
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| 1 |
Ki = 100 nM
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CP0864941
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(5S,11S)-5-sec-butyl-18-chloro-11-(3-chlorobenzyl)-7-methyl-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C32H42Cl2N4O4
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1
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| 1 |
Ki = 100 nM
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CP0864942
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(8S,18S)-8-sec-butyl-18-(3-chlorobenzyl)-6,9,13,16,19-pentaazaspiro[4.15]icosane-7,17,20-trione
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C26H40ClN5O3
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1
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| 1 |
Ki = 100 nM
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CP0864945
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11-benzyl-5-sec-butyl-8-(hydroxymethyl)-7-methyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C30H42N4O5
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1
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| 1 |
Ki = 100 nM
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CP0864949
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(3S,6R,9R)-9-benzyl-3-sec-butyl-5,6-dimethyl-2,3,5,6,8,9,12,13,14,15-decahydro-1H-benzo[l][1,4,7,10]tetraazacycloheptadecine-4,7,10(11H)-trione
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C30H42N4O3
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1
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| 1 |
Ki = 100 nM
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CP0864950
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(5S,8R,11R)-11-benzyl-5-sec-butyl-7,8-dimethyl-6,9,12-trioxo-3,4,5,6,7,8,9,10,11,12,13,14,15,16-tetradecahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-18-carboxylic acid
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C31H42N4O6
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1
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| 1 |
Ki = 100 nM
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CP0867092
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(5S,8R,11R)-5,11-di-sec-butyl-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C27H44N4O4
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1
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| 1 |
Ki = 100 nM
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CP0867093
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(5S,8R,11R)-11-benzyl-5-sec-butyl-7,8-dimethyl-1-oxa-4,7,10,13-tetraazacycloheptadec-15-ene-6,9,12-trione
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C25H38N4O4
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1
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| 1 |
Ki = 100 nM
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CP0867094
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(3S,6R,9R)-9-benzyl-3-sec-butyl-5,6-dimethyl-2,3,5,6,8,9,11,12-octahydro-1H-benzo[l][1,4,7,10]tetraazacycloheptadecine-4,7,10(15H)-trione
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C30H40N4O3
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1
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| 1 |
Ki = 100 nM
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CP0869426
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(8S,20S)-8-sec-butyl-20-(3-chlorobenzyl)-6,9,18,21-tetraazaspiro[4.17]docosane-7,19,22-trione
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C29H45ClN4O3
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1
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| 1 |
Ki = 100 nM
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CP0871110
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(5S,11S)-11-benzyl-5-butyl-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C32H44N4O4
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1
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| 1 |
Ki = 100 nM
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CP0871223
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(5S,11S)-11-benzyl-5-(4-methoxybenzyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C36H42N4O5
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1
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| 1 |
Ki = 100 nM
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CP0871224
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11-benzyl-5-ethyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C30H38N4O4
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1
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| 1 |
Ki = 100 nM
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CP0873084
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(8R,14S)-8-benzyl-12-methyl-14-propyl-5,6,8,9,11,12,15,16-octahydrodibenzo[b,p][1,5,8,11,14]thiatetraazacycloheptadecine-7,10,13(14H)-trione
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C31H36N4O3S
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1
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| 1 |
Ki = 100 nM
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CP0875142
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(5S,11S)-11-benzyl-5-isopropyl-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C31H42N4O4
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1
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| 1 |
Ki = 100 nM
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CP0875143
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(5S,11S)-11-benzyl-5-isopropyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopropane]-6,9,12(7H)-trione
Show/Hide
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C29H36N4O4
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1
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| 1 |
Ki = 100 nM
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CP0875144
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(3aS,6R,9R)-9-benzyl-5,6-dimethyl-3,3a,5,6,8,9,11,12,13,14,20,21-dodecahydro-1H-benzo[q]pyrrolo[1,2-d][1,4,7,10,13]oxatetraazacyclooctadecine-4,7,10(2H)-trione
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C29H38N4O4
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1
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| 1 |
Ki = 100 nM
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CP0875151
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(3S,9S)-3-sec-butyl-9-(3-chlorobenzyl)-2,3,8,9,11,12,13,14,15,16-decahydro-1H-spiro[benzo[l][1,4,7,10]tetraazacyclooctadecine-6,1'-cyclopentane]-4,7,10(5H)-trione
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C33H45ClN4O3
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1
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| 1 |
Ki = 100 nM
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CP0875156
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(5R,8S,11S)-11-benzyl-5-isopropyl-8-propyl-4,5,7,8,10,11,13,14-octahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C30H40N4O4
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1
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| 1 |
Ki = 100 nM
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CP0875196
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(5S,11S)-5-isobutyl-11-(thiophen-2-ylmethyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C30H40N4O4S
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1
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| 1 |
Ki = 100 nM
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CP0875209
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(5S,8R,11R)-11-benzyl-5-sec-butyl-8-ethyl-7,10-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C31H42N4O4
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1
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| 1 |
Ki = 100 nM
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CP0875585
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2-(((5S,11S)-11-(4-chlorobenzyl)-6,9,12-trioxo-2,3,4,5,6,7,9,10,11,12,13,14-dodecahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-5-yl)methyl)benzonitrile
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C36H38ClN5O4
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1
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| 1 |
Ki = 100 nM
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CP0875586
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(8S,20S)-8-sec-butyl-20-(3-chlorobenzyl)-12-oxa-6,9,18,21-tetraazaspiro[4.17]docos-14-ene-7,19,22-trione
Show/Hide
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C28H41ClN4O4
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1
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| 1 |
Ki = 100 nM
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CP0875587
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(6R,9R,12S)-12-cyclopropyl-6-(4-fluorobenzyl)-9,10-dimethyl-3,4,6,7,9,10,12,13,14,15-decahydrobenzo[b][1,4,7,10,13,16]dioxatetraazacyclooctadecine-5,8,11(2H)-trione
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C28H35FN4O5
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1
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| 1 |
Ki = 100 nM
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CP0883271
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(S)-11-(3-chlorobenzyl)-5,5,8,8-tetramethyl-4,5,7,8,10,11,13,14-octahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C28H35ClN4O4
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1
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| 1 |
Ki = 100 nM
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CP0883358
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(5S,11R)-11-benzyl-5-propyl-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C31H42N4O4
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1
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| 1 |
Ki = 100 nM
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CP0883373
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(5S,8R,11R)-11-benzyl-4,7,8-trimethyl-5-propyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C30H42N4O4
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1
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| 1 |
Ki = 100 nM
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CP0883417
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11-benzyl-5-isopropyl-7,8-dimethyl-4,5,7,8,10,11,13,14-octahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C29H38N4O4
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1
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| 1 |
Ki = 100 nM
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CP0883441
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(Z)-5-sec-butyl-11-(3,5-difluorobenzyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C32H40F2N4O4
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1
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| 1 |
Ki = 100 nM
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CP0888137
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(5S,11S)-11-(4-chlorobenzyl)-5-(methoxymethyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C30H37ClN4O5
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1
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| 1 |
Ki = 100 nM
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CP0888139
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(5S,11S)-11-(benzyloxymethyl)-5-sec-butyl-8,8-dimethyl-4,5,7,8,10,11,13,14-octahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C31H42N4O5
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1
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| 1 |
Ki = 100 nM
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CP0888295
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(5S,8R,11R)-11-benzyl-5-sec-butyl-7,8-dimethyl-2,3,4,5,7,8,10,11,14,15-decahydro-1H-benzo[n][1,4,7,10]tetraazacyclononadecine-6,9,12(13H)-trione
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C32H44N4O3
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1
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| 1 |
Ki = 100 nM
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CP0894000
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(5S,8R,11R)-11-benzyl-5-sec-butyl-8-isopropyl-7-methyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C32H46N4O4
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1
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| 1 |
Ki = 100 nM
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CP0894703
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(5S,11S)-11-benzyl-5-(2-chlorobenzyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C35H39ClN4O4
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1
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| 1 |
Ki = 100 nM
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CP0895643
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5-sec-butyl-11-(3,4-difluorobenzyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C32H40F2N4O4
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1
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| 1 |
Ki = 100 nM
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CP0899601
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(8S,20R)-8-sec-butyl-20-(3-chlorobenzyl)-12-oxa-6,9,18,21-tetraazaspiro[4.17]docosane-7,19,22-trione
Show/Hide
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C28H43ClN4O4
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1
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| 1 |
Ki = 100 nM
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CP0899615
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(5S,8R,11R)-11-benzyl-5-sec-butyl-7,8-dimethyl-1-oxa-4,7,10,13-tetraazacyclooctadec-16-ene-6,9,12-trione
Show/Hide
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C26H40N4O4
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1
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| 1 |
Ki = 100 nM
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CP0899616
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(5S,8R,11R)-11-((1H-imidazol-4-yl)methyl)-5-sec-butyl-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C27H40N6O4
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1
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| 1 |
Ki = 100 nM
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CP0901767
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(5S,8R,11R)-5-cyclopropyl-11-(4-fluorobenzyl)-7,8-dimethyl-18-(trifluoromethyl)-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C30H36F4N4O4
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1
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| 1 |
Ki = 100 nM
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CP0901793
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(5S,8R,11S,Z)-11-benzyl-5-sec-butyl-8-methyl-4,5,7,8,10,11,13,14-octahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C29H38N4O4
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1
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| 1 |
Ki = 100 nM
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CP0901818
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(5S,8R,11R)-5-sec-butyl-7,8-dimethyl-11-(thiazol-4-ylmethyl)-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C27H39N5O4S
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1
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| 1 |
Ki = 100 nM
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CP0901819
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(5S,8S,11R)-11-benzyl-5,8-di-sec-butyl-7-methyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C33H48N4O4
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1
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| 1 |
Ki = 100 nM
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CP0902544
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(5S,11S)-11-(benzyloxymethyl)-5-sec-butyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C33H44N4O5
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1
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| 1 |
Ki = 100 nM
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CP0902545
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11-(benzyloxymethyl)-5-sec-butyl-8,8-dimethyl-4,5,7,8,10,11,13,14-octahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C31H42N4O5
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1
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| 1 |
Ki = 100 nM
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CP0902656
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(5R,8S,11S)-8,11-dibutyl-5-isopropyl-4,5,7,8,10,11,13,14-octahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C28H44N4O4
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1
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| 1 |
Ki = 100 nM
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CP0902657
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(5S,11S)-11-benzyl-5-isopropyl-2,2',3,3',4,5,5',6',10,11,13,14-dodecahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,4'-thiopyran]-6,9,12(7H)-trione
Show/Hide
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C31H40N4O4S
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1
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| 1 |
Ki = 100 nM
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CP0902692
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(8S,18S)-8-sec-butyl-18-(3-chlorobenzyl)-6,9,16,19-tetraazaspiro[4.15]icosane-7,17,20-trione
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C27H41ClN4O3
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1
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| 1 |
Ki = 100 nM
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CP0902766
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(5S,8S,11R)-11-benzyl-5-sec-butyl-8-ethyl-7-methyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C31H44N4O4
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1
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| 1 |
Ki = 100 nM
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CP0902774
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(5R,8R,11R)-5-(aminomethyl)-11-(4-fluorobenzyl)-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C27H36FN5O4
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1
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| 1 |
Ki = 100 nM
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CP0902775
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(8S,11R)-11-(3-chlorobenzyl)-7,8-dimethyl-3,4,7,8,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-5,1'-cyclopentane]-6,9,12(2H)-trione
Show/Hide
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C30H37ClN4O4
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1
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| 1 |
Ki = 100 nM
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CP0903659
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(5S,11S)-5-((1H-imidazol-4-yl)methyl)-11-benzyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C32H38N6O4
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1
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| 1 |
Ki = 100 nM
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CP0903661
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(5'S,11'S)-5'-sec-butyl-11'-(3-chlorobenzyl)-7'-methyl-2',3',4',5',10',11',13',14',15',16'-decahydrospiro[cyclopentane-1,8'-pyrido[2,3-q][1,4,7,10,13]oxatetraazacyclooctadecine]-6',9',12'(7'H)-trione
Show/Hide
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C31H42ClN5O4
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1
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| 1 |
Ki = 100 nM
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CP0903664
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(5S,8R)-5,11-di-sec-butyl-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C27H44N4O4
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1
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| 1 |
Ki = 100 nM
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CP0903686
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9-benzyl-3-sec-butyl-5,6-dimethyl-2,3,5,6,8,9,12,13,14,15-decahydro-1H-benzo[l][1,4,7,10]tetraazacycloheptadecine-4,7,10(11H)-trione
Show/Hide
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C30H42N4O3
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1
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| 1 |
Ki = 100 nM
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CP0903688
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(5S,8R,11R)-5-(3-aminopropyl)-11-(4-fluorobenzyl)-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C29H40FN5O4
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1
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| 1 |
Ki = 100 nM
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CP0903689
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(8S,20S)-8-sec-butyl-20-(3-chlorobenzyl)-12,15-dioxa-6,9,18,21-tetraazaspiro[4.17]docosane-7,19,22-trione
Show/Hide
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C27H41ClN4O5
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1
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| 1 |
Ki = 100 nM
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CP0903690
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3-benzyl-9-sec-butyl-6,7-dimethyl-1,4,7,10-tetraazacyclooctadecane-2,5,8-trione
Show/Hide
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C27H44N4O3
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1
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| 1 |
Ki = 100 nM
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CP0906043
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(5S,8S,11S)-11-benzyl-5-sec-butyl-8-isopropyl-7-methyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C32H46N4O4
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1
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| 1 |
Ki = 100 nM
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CP0906044
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(5S,11R)-11-benzyl-7-ethyl-5-propyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C29H40N4O4
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1
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| 1 |
Ki = 100 nM
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CP0911120
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(5S,8R,11R)-5-cyclopropyl-11-(3,4-dimethoxybenzyl)-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C31H42N4O6
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1
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| 1 |
Ki = 100 nM
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CP0911459
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(8R)-5-cyclopropyl-11-(4-fluorobenzyl)-7,8-dimethyl-1-oxa-4,7,10,13-tetraazacyclooctadec-16-ene-6,9,12-trione
Show/Hide
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C25H35FN4O4
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1
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| 1 |
Ki = 100 nM
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CP0911462
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9-sec-butyl-15-(3-tert-butylbenzyl)-10,13,16-trimethylene-6,7,8,9,10,11,13,14,15,16,17,18-dodecahydro-5H-spiro[benzo[18]annulene-12,1'-cyclopentane]
Show/Hide
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C33H41F3N4O4
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1
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| 1 |
Ki = 100 nM
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CP0911464
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(5S,11S)-5-sec-butyl-11-(3-chlorobenzyl)-16,16-dimethyl-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C34H47ClN4O4
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1
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| 1 |
Ki = 100 nM
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CP0911467
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(5S,8R,11R)-5-cyclopropyl-11-(4-fluorobenzyl)-7,8,16,16-tetramethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C31H41FN4O4
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1
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| 1 |
Ki = 100 nM
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CP0911470
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(5S,11S)-5,11-diisobutyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C29H44N4O4
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1
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| 1 |
Ki = 100 nM
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CP0913568
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(8S,20S)-8-sec-butyl-20-(3-chlorobenzyl)-6,9,18,21-tetraazaspiro[4.17]docos-14-ene-7,19,22-trione
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C29H43ClN4O3
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1
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| 1 |
Ki = 100 nM
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CP0913579
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(5S,11S)-11-benzyl-5-isopropyl-2,2',3,3',4,5,5',6',10,11,13,14-dodecahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,4'-pyran]-6,9,12(7H)-trione
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C31H40N4O5
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1
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| 1 |
Ki = 100 nM
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CP0914434
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(5S,11S)-11-benzyl-5-(naphthalen-2-ylmethyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C39H42N4O4
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1
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| 1 |
Ki = 100 nM
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CP0914435
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(5S,11S)-11-benzyl-5-(thiophen-2-ylmethyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C33H38N4O4S
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1
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| 1 |
Ki = 100 nM
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CP0915636
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(5S,11S)-5-sec-butyl-11-(3-chlorobenzyl)-19-fluoro-7-methyl-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C33H44ClFN4O4
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1
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| 1 |
Ki = 100 nM
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CP0915643
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(8S,19S)-8-sec-butyl-19-(3-chlorobenzyl)-6,9,17,20-tetraazaspiro[4.16]henicosane-7,18,21-trione
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C28H43ClN4O3
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1
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| 1 |
Ki = 100 nM
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CP0919530
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(5S,8R,11R)-11-benzyl-5-((R)-1-hydroxyethyl)-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C28H38N4O5
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1
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| 1 |
Ki = 100 nM
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CP0919546
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N-((5S,8R,11R)-5-cyclopropyl-11-(4-fluorobenzyl)-7,8-dimethyl-6,9,12-trioxo-3,4,5,6,7,8,9,10,11,12,13,14,15,16-tetradecahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecin-19-yl)methanesulfonamide
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C30H40FN5O6S
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1
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| 1 |
Ki = 100 nM
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CP0919925
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(5S,11S)-5,11-dibenzyl-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C35H42N4O4
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1
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| 1 |
Ki = 100 nM
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CP0919926
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(5S,11R)-11-benzyl-5-propyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C27H36N4O4
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1
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| 1 |
Ki = 100 nM
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CP0921116
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(5S,11S)-11-benzyl-5-methyl-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C29H38N4O4
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1
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| 1 |
Ki = 100 nM
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CP0921119
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(5S,11S,Z)-5-sec-butyl-11-(3-chlorobenzyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C32H41ClN4O4
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1
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| 1 |
Ki = 100 nM
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CP0924060
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(3aR,6R,20S)-6-benzyl-20-propyl-3,3a,5,6,8,9,10,11,17,18,19,20-dodecahydro-1H-benzo[q]pyrrolo[1,2-g][1,4,7,10,13]oxatetraazacyclooctadecine-4,7,21(2H)-trione
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C30H40N4O4
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1
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| 1 |
Ki = 100 nM
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CP0924063
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(5S,11R)-8-(benzyloxymethyl)-5-sec-butyl-11-(4-fluorobenzyl)-7-methyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C37H47FN4O5
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1
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| 1 |
Ki = 100 nM
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CP0926571
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(5S,11R)-11-benzyl-8,8-dimethyl-5-propyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C29H40N4O4
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1
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| 1 |
Ki = 100 nM
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CP0932750
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(5S,11S)-11-(4-chlorobenzyl)-5-(2-methoxybenzyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C36H41ClN4O5
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1
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| 1 |
Ki = 100 nM
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CP0933068
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(5S,11S)-11-benzyl-5-(thiazol-4-ylmethyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C32H37N5O4S
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1
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| 1 |
Ki = 100 nM
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CP0945374
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(5S,11S)-11-benzyl-5-phenethyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C36H42N4O4
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1
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| 1 |
Ki = 100 nM
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CP0945398
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(4S,7R,10R)-10-benzyl-4-sec-butyl-6,7-dimethyl-1,2,3,4,6,7,9,10,13,14,15,16-dodecahydrobenzo[m][1,4,7,10]tetraazacyclooctadecine-5,8,11(12H)-trione
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C31H44N4O3
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1
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| 1 |
Ki = 100 nM
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CP0947207
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(5S,11S)-11-benzyl-5-isopropyl-1',2,3,3',4,5,10,11,13,14-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,2'-indene]-6,9,12(7H)-trione
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C35H40N4O4
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1
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| 1 |
Ki = 100 nM
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CP0947208
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(5S,8R,11R)-5-sec-butyl-11-isopropyl-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C26H42N4O4
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1
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| 1 |
Ki = 100 nM
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CP0947291
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(4S,7R,10R)-10-benzyl-4-sec-butyl-6,7-dimethyl-3,4,6,7,9,10,12,13-octahydro-1H-benzo[m][1,4,7,10]tetraazacycloheptadecine-5,8,11(2H)-trione
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C30H40N4O3
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1
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| 1 |
Ki = 100 nM
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CP0949435
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(5S,8R,11S)-5-cyclopropyl-11-(4-fluorobenzyl)-7,8-dimethyl-1-oxa-4,7,10,13-tetraazacyclooctadecane-6,9,12-trione
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C25H37FN4O4
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1
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| 1 |
Ki = 100 nM
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CP0958206
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(8S,11S)-11-(3-chlorobenzyl)-8-methyl-3,4,7,8,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-5,1'-cyclopentane]-6,9,12(2H)-trione
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C29H35ClN4O4
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1
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| 1 |
Ki = 100 nM
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CP0960138
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(5S,8R,11R)-11-(4-fluorobenzyl)-5-(methoxymethyl)-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C28H37FN4O5
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1
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| 1 |
Ki = 100 nM
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CP0963861
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(5S,11S)-5-sec-butyl-11-(thiophen-3-ylmethyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C30H40N4O4S
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1
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| 1 |
Ki = 100 nM
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CP0966785
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(5S,11S)-11-benzyl-5-(hydroxymethyl)-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C29H38N4O5
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1
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| 1 |
Ki = 100 nM
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CP0864954
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(5S,11R)-11-benzyl-5-isopropyl-7-methyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C28H38N4O4
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1
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| 1 |
Ki = 107 nM
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CP0946595
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(R)-N-[2-(2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethylamino]-2-oxoethyl)benzamide
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C37H36N6O3
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1
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| 1 |
Ki = 115 nM
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CP0907058
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(R,E)-N-[2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethyl]-2-cyano-3-(4-methoxyphenyl)-acrylamide
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C39H36N6O3
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1
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| 1 |
Ki = 122 nM
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CP0411690
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5-methoxy-2-[2-[2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]-2-oxoethoxy]benzamide
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C31H35N5O4
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1
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| 1 |
Ki = 127 nM
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CP0914507
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(R)-N-[2-(2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethylamino)-2-oxoethyl]-3-phenylpropiolamide
Show/Hide
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C39H36N6O3
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1
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| 1 |
Ki = 130 nM
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CP0923333
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(R)-N-[2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethyl]-2-(2-aminoacetamido)acetamide
Show/Hide
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C32H35N7O3
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1
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| 1 |
Ki = 130 nM
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CP0923155
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(R)-N-[2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethyl]-2-(benzylamino)acetamide
Show/Hide
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C37H38N6O2
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1
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| 1 |
Ki = 136 nM
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CP0498111
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5-methoxy-2-[3-[2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]-3-oxopropyl]benzamide
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C32H37N5O3
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1
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| 1 |
Ki = 139 nM
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CP0410420
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2-(1-methylpyrazolo[3,4-b]pyridin-3-yl)-1-[2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
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C30H33N7O
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1
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| 1 |
Ki = 166 nM
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CP0958788
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N-[2-((R)-2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethylamino)-2-oxoethyl]-2-cyano-3-phenylpropanamide
Show/Hide
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C40H39N7O3
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1
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| 1 |
Ki = 166 nM
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CP0869402
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(5S,8R,11R)-11-benzyl-5-sec-butyl-8-methyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C29H40N4O4
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1
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| 1 |
Ki = 177 nM
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CP0953360
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(R)-N-[2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethyl]-2-(dimethylamino)acetamide
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C32H36N6O2
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1
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| 1 |
Ki = 200 nM
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CP0926417
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(R)-N-[2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethyl]-2-(4-aminopiperidin-1-yl)acetamide
Show/Hide
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C35H41N7O2
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1
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| 1 |
Ki = 220 nM
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CP0875559
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(R)-N-[2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethyl]-2-(diethylamino)acetamide
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C34H40N6O2
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1
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| 1 |
Ki = 230 nM
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CP0498109
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2-methoxy-5-[2-[2-[(1R)-5-(4-methylpyrimidin-2-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]-2-oxoethyl]pyridine-4-carboxamide
Show/Hide
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C30H34N6O3
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1
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| 1 |
Ki = 263 nM
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CP0379662
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2-(4-methoxyphenyl)-1-[2-[(1S)-5-pyrimidin-2-yl-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
Show/Hide
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C29H32N4O2
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1
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| 1 |
Ki = 275.42 nM
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CP0924603
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(R)-N-[2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethyl]-2-(ethylamino)acetamide
Show/Hide
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C32H36N6O2
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1
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| 1 |
Ki = 300 nM
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CP0907059
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(R)-N-[2-(2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethylamino)-2-oxoethyl]cinnamamide
Show/Hide
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C39H38N6O3
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1
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| 1 |
Ki = 370 nM
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CP0902847
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(R)-2-[2-(2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethylamino)-2-oxoethylamino]acetic acid
Show/Hide
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C32H34N6O4
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1
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| 1 |
Ki = 617 nM
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CP0084688
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(6S,12R)-6-(4-aminobutyl)-12-benzyl-8-methyl-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-triene-7,10,13-trione
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C29H41N5O4
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1
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| 1 |
Ki = 1000 nM
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CP0151993
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(6R,12R)-12-benzyl-8-methyl-6-propyl-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-triene-7,10,13-trione
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C28H38N4O4
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1
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| 1 |
Ki = 1000 nM
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CP0848574
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(3aS,6S,20S)-6-benzyl-20-isobutyl-3,3a,5,6,8,9,10,11,17,18,19,20-dodecahydro-1H-benzo[q]pyrrolo[1,2-g][1,4,7,10,13]oxatetraazacyclooctadecine-4,7,21(2H)-trione
Show/Hide
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C31H42N4O4
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1
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| 1 |
Ki = 1000 nM
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CP0848578
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(9R,12R,15S)-15-cyclopropyl-9-(4-fluorobenzyl)-12,13-dimethyl-1,4-dioxa-7,10,13,16-tetraazacyclooctadecane-8,11,14-trione
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C24H35FN4O5
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1
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| 1 |
Ki = 1000 nM
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CP0851209
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(5S,8R,11R)-11-benzyl-5,8-di-sec-butyl-7-methyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C33H48N4O4
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1
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| 1 |
Ki = 1000 nM
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CP0863067
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11-benzyl-5-sec-butyl-8-ethyl-7,10-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C31H42N4O4
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1
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| 1 |
Ki = 1000 nM
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CP0864412
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(5S,11S)-11-benzyl-5-isopropyl-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopropane]-6,9,12(7H)-trione
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C29H38N4O4
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1
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| 1 |
Ki = 1000 nM
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CP0864944
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(8S,17S)-8-sec-butyl-17-(3-chlorobenzyl)-6,9,15,18-tetraazaspiro[4.14]nonadecane-7,16,19-trione
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C26H39ClN4O3
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1
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| 1 |
Ki = 1000 nM
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CP0864966
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(5S,8S,11R)-8-(4-aminobutyl)-11-benzyl-5-propyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C31H45N5O4
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1
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| 1 |
Ki = 1000 nM
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CP0867085
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(5R,11S)-5-Benzyl-9-methyl-11-propyl-3,6,9,12-tetraaza-bicyclo[12.3.1]octadeca-1(17),14(18),15-triene-4,7,10-trione
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C25H32N4O3
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1
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| 1 |
Ki = 1000 nM
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CP0867086
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(5S,8S,11S)-11-benzyl-5-isobutyl-8-methyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C29H40N4O4
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1
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| 1 |
Ki = 1000 nM
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CP0867136
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(5'S,11'S)-11'-benzyl-5'-isobutyl-2',3',4',5',10',11',13',14',15',16'-decahydrospiro[cyclopentane-1,8'-pyrido[2,3-q][1,4,7,10,13]oxatetraazacyclooctadecine]-6',9',12'(7'H)-trione
Show/Hide
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C31H43N5O4
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1
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| 1 |
Ki = 1000 nM
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CP0869398
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ethyl 3-((5S,11S)-5-isobutyl-6,9,12-trioxo-2,3,4,5,6,7,9,10,11,12,13,14-dodecahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-11-yl)propanoate
Show/Hide
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C30H44N4O6
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1
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| 1 |
Ki = 1000 nM
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CP0871221
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(5S,8R,11S)-11-benzyl-5-isobutyl-8-methyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C29H40N4O4
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1
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| 1 |
Ki = 1000 nM
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CP0871222
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(5S,11S)-11-benzyl-5-(4-chlorobenzyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C35H39ClN4O4
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1
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| 1 |
Ki = 1000 nM
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CP0873137
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(5S,11S)-7-methyl-11-((S)-1-phenylethyl)-5-propyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C29H40N4O4
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1
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| 1 |
Ki = 1000 nM
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CP0875138
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(5S,8R,11R)-8,11-dibenzyl-5-propyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C34H42N4O4
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1
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| 1 |
Ki = 1000 nM
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CP0875153
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15-cyclopropyl-9-(4-fluorobenzyl)-12,13-dimethyl-1,4-dioxa-7,10,13,16-tetraazacyclooctadecane-8,11,14-trione
Show/Hide
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C24H35FN4O5
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1
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| 1 |
Ki = 1000 nM
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CP0875577
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(2S,5S,11S,Z)-5-sec-butyl-11-(3-chlorobenzyl)-2-methyl-2,3,4,4',5,5',10,11,13,14-decahydro-2'H-spiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,3'-furan]-6,9,12(7H)-trione
Show/Hide
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C32H41ClN4O5
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1
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| 1 |
Ki = 1000 nM
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CP0883295
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(5S,11R)-11-benzyl-5,7-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C26H34N4O4
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1
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| 1 |
Ki = 1000 nM
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CP0883377
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(5S,11S)-11-((1H-indol-3-yl)methyl)-5-isobutyl-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C34H45N5O4
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1
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| 1 |
Ki = 1000 nM
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CP0883402
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(5S,11S)-5-isobutyl-11-phenethyl-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C33H46N4O4
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1
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| 1 |
Ki = 1000 nM
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CP0893951
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(3aS,6R,20S)-6-benzyl-20-propyl-3,3a,5,6,8,9,10,11,17,18,19,20-dodecahydro-1H-benzo[q]pyrrolo[1,2-g][1,4,7,10,13]oxatetraazacyclooctadecine-4,7,21(2H)-trione
Show/Hide
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C30H40N4O4
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1
|
| 1 |
Ki = 1000 nM
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CP0894004
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(5S,11S)-11-benzyl-5-isobutyl-4-methyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C33H44N4O4
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1
|
| 1 |
Ki = 1000 nM
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CP0894702
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(7'S,13'S)-13'-benzyl-7'-isobutyl-6',7',12',13',15',16'-hexahydro-5'H-spiro[cyclopentane-1,10'-dibenzo[b,p][1,5,8,11,14]thiatetraazacycloheptadecine]-8',11',14'(9'H)-trione
Show/Hide
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C35H42N4O3S
|
1
|
| 1 |
Ki = 1000 nM
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CP0894738
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(2S,5R,11S)-11-(3-chlorobenzyl)-5-isobutyl-2-methyl-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C33H45ClN4O4
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1
|
| 1 |
Ki = 1000 nM
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CP0899604
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(5S,11S)-5-sec-butyl-11-(3-chlorobenzyl)-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C31H42ClN5O4
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1
|
| 1 |
Ki = 1000 nM
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CP0901765
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(3aR,6S,20S)-6-benzyl-20-isobutyl-3,3a,5,6,8,9,10,11,17,18,19,20-dodecahydro-1H-benzo[q]pyrrolo[1,2-g][1,4,7,10,13]oxatetraazacyclooctadecine-4,7,21(2H)-trione
Show/Hide
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C31H42N4O4
|
1
|
| 1 |
Ki = 1000 nM
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CP0911455
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(S)-11-benzyl-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C28H36N4O4
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1
|
| 1 |
Ki = 1000 nM
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CP0911456
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(5S,11S)-5-isobutyl-11-(pyridin-4-ylmethyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C31H41N5O4
|
1
|
| 1 |
Ki = 1000 nM
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CP0911469
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4-(((5S,11S)-5-sec-butyl-7-methyl-6,9,12-trioxo-2,3,4,5,6,7,9,10,11,12,13,14-dodecahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-11-yl)methyl)benzoic acid
Show/Hide
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C34H44N4O6
|
1
|
| 1 |
Ki = 1000 nM
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|
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CP0913561
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(5S,11S)-11-(4-hydroxybenzyl)-5-isobutyl-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C32H44N4O5
|
1
|
| 1 |
Ki = 1000 nM
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|
|
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CP0914436
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(5S,8R,11R)-11-benzyl-8-(tert-butoxymethyl)-5-sec-butyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C33H48N4O5
|
1
|
| 1 |
Ki = 1000 nM
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CP0933069
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(5S,8S,11R)-11-benzyl-8-isobutyl-5-propyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C31H44N4O4
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1
|
| 1 |
Ki = 1000 nM
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CP0933070
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(5S,8S,11R)-11-benzyl-8-methyl-5-propyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C28H38N4O4
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1
|
| 1 |
Ki = 1000 nM
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CP0948679
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(5S,11S)-11-benzyl-5-isobutyl-8,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C30H42N4O4
|
1
|
| 1 |
Ki = 1000 nM
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CP0949621
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(5S,11S)-11-benzyl-5-(naphthalen-1-ylmethyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C39H42N4O4
|
1
|
| 1 |
Ki = 1000 nM
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CP0392009
|
2-(5-methoxypyridin-2-yl)-1-[2-[(1S)-1-(4-pyrimidin-2-ylphenyl)ethyl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
Show/Hide
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C27H31N5O2
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1
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| 1 |
Ki = 1122.02 nM
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CP0456879
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2-(5-methoxypyridin-2-yl)-1-[2-[(1S)-5-(1,3-thiazol-2-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
Show/Hide
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C27H30N4O2S
|
1
|
| 1 |
Ki = 1380.38 nM
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CP0902901
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(R)-[2-(2-(1H-Indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethylamino)-2-oxoethyl]carbamoyl cyanide
Show/Hide
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C32H31N7O3
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1
|
| 1 |
Ki = 1600 nM
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CP0379665
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2-(5-methoxypyridin-2-yl)-1-[2-[1-(4-pyrimidin-2-ylphenyl)ethyl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
Show/Hide
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C27H31N5O2
|
1
|
| 1 |
Ki = 1698.24 nM
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CP0392010
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2-(5-methoxypyridin-2-yl)-1-[2-[2-methoxy-1-(4-pyrimidin-2-ylphenyl)ethyl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
Show/Hide
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C28H33N5O3
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1
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| 1 |
Ki = 3630.78 nM
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CP0084689
|
(6S,12R)-12-(3-aminopropyl)-8-methyl-6-propyl-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-triene-7,10,13-trione
Show/Hide
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C24H39N5O4
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1
|
| 1 |
Ki > 10000 nM
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CP0205853
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3-[(6S,12R)-12-benzyl-8-methyl-7,10,13-trioxo-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-trien-6-yl]propanoic acid
Show/Hide
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C28H36N4O6
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1
|
| 1 |
Ki > 10000 nM
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|
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CP0205854
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(6S,12R)-12-(hydroxymethyl)-8-methyl-6-propyl-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-triene-7,10,13-trione
Show/Hide
|
C22H34N4O5
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1
|
| 1 |
Ki > 10000 nM
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|
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CP0238495
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3-[(6S,12R)-8-methyl-7,10,13-trioxo-6-propyl-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-trien-12-yl]propanoic acid
Show/Hide
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C24H36N4O6
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1
|
| 1 |
Ki > 10000 nM
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|
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CP0238530
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(6S,12R)-12-benzyl-6-(hydroxymethyl)-8-methyl-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-triene-7,10,13-trione
Show/Hide
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C26H34N4O5
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1
|
| 1 |
Ki > 10000 nM
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CP0260071
|
(3R,6R,9S)-3-benzyl-9-[(2S)-butan-2-yl]-6,7-dimethyl-1,4,7,10-tetrazacycloheptadecane-2,5,8-trione
Show/Hide
|
C26H42N4O3
|
1
|
| 1 |
Ki > 10000 nM
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CP0848227
|
(4S,10R)-10-Benzyl-6-methyl-4-propyl-3,6,9,12-tetraaza-bicyclo[13.3.1]nonadeca-1(19),15,17-triene-5,8,11-trione
Show/Hide
|
C26H34N4O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
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CP0848572
|
(5S,8R,11R)-5-sec-butyl-11-ethyl-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C25H40N4O4
|
1
|
| 1 |
Ki > 10000 nM
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CP0848573
|
(10R,13R,16S)-10-benzyl-16-sec-butyl-1,3,13,14-tetramethyl-5,6,7,8,10,11,13,14,17,18,19,20-dodecahydropyrimido[4,5-n][1,4,7,10]tetraazacyclooctadecine-2,4,9,12,15(1H,3H,16H)-pentaone
Show/Hide
|
C31H46N6O5
|
1
|
| 1 |
Ki > 10000 nM
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|
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CP0851204
|
(R)-11-benzyl-7-methyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
|
C25H32N4O4
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1
|
| 1 |
Ki > 10000 nM
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CP0851205
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(5S,11S)-11-(4-aminobutyl)-5-isobutyl-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
|
C29H47N5O4
|
1
|
| 1 |
Ki > 10000 nM
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CP0851206
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(5S,11S)-4-acetyl-11-benzyl-5-isobutyl-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C34H46N4O5
|
1
|
| 1 |
Ki > 10000 nM
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CP0851212
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(5S,8R,11S)-5-sec-butyl-11-ethyl-7,8-dimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
|
C25H40N4O4
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1
|
| 1 |
Ki > 10000 nM
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|
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CP0858818
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(5S,11S-5-isobutyl-11-(thiazol-4-ylmethyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
|
C29H39N5O4S
|
1
|
| 1 |
Ki > 10000 nM
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|
|
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CP0861114
|
(3R,9S)-3-benzyl-7-methyl-9-propyl-1,4,7,10-tetraazacyclohexadec-13-ene-2,5,8-trione
Show/Hide
|
C23H34N4O3
|
1
|
| 1 |
Ki > 10000 nM
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|
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CP0864446
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(5S,11S)-5-isobutyl-11-methyl-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
|
C26H40N4O4
|
1
|
| 1 |
Ki > 10000 nM
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|
|
|
CP0864932
|
(5R,11S)-11-benzyl-5-isobutyl-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
|
C32H44N4O4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0864934
|
(5S,11S)-5-isobutyl-11-isopropyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
|
C28H42N4O4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0864964
|
(5S,11R)-4-acetyl-11-benzyl-7-methyl-5-propyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
|
C30H40N4O5
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0864965
|
(5S,8R,11R)-11-benzyl-8-isobutyl-5-propyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
|
C31H44N4O4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0867088
|
(8R,11R)-11-benzyl-7,8-dimethyl-3,4,7,8,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-5,1'-cyclopropane]-6,9,12(2H)-trione
Show/Hide
|
C28H36N4O4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0867090
|
(5S,11S)-11-sec-butyl-5-isobutyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
|
C29H44N4O4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0867095
|
(4S,21S)-2-Benzyl-18-sec-butyl-14-oxa-1,4,17,20-tetraaza-tricyclo[19.2.1.0(8,13)]tetracosa-8,10,12-triene-3,19,24-trione
Show/Hide
|
C30H40N4O4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0867135
|
3-((5S,11S)-11-benzyl-6,9,12-trioxo-2,3,4,5,6,7,9,10,11,12,13,14,15,16-tetradecahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-5-yl)propanoic acid
Show/Hide
|
C31H40N4O6
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0869400
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3-((5S,8S,11R)-11-benzyl-6,9,12-trioxo-5-propyl-3,4,5,6,7,8,9,10,11,12,13,14,15,16-tetradecahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecin-8-yl)propanoic acid
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C30H40N4O6
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1
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| 1 |
Ki > 10000 nM
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CP0869401
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(5R,11S)-11-benzyl-7-methyl-5-propyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C28H38N4O4
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1
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| 1 |
Ki > 10000 nM
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CP0869432
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(5S,8S,11R)-8,11-dibenzyl-5-propyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C34H42N4O4
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1
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| 1 |
Ki > 10000 nM
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CP0871112
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11-benzyl-5,8-di-sec-butyl-7-methyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C33H48N4O4
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1
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| 1 |
Ki > 10000 nM
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CP0871227
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3-benzyl-9-sec-butyl-6,7-dimethyl-1,4,7,10-tetraazacycloheptadecane-2,5,8-trione
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C26H42N4O3
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1
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| 1 |
Ki > 10000 nM
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CP0875137
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(5S,11S)-11-benzyl-5-(4-fluorobenzyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C35H39FN4O4
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1
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| 1 |
Ki > 10000 nM
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CP0875158
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(S)-7-methyl-5-propyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C21H32N4O4
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1
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| 1 |
Ki > 10000 nM
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CP0875167
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(5S,11S)-4-acetyl-11-benzyl-5-isobutyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C34H44N4O5
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1
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| 1 |
Ki > 10000 nM
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CP0875185
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(6R,12S)-6-benzyl-10-methyl-12-propyl-1-oxa-4,7,10,13-tetraazacyclopentadecane-5,8,11-trione
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C21H32N4O4
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1
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| 1 |
Ki > 10000 nM
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CP0875583
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(6S,12S)-6-benzyl-12-isobutyl-spiro[4,7,10,13-tetrazabicyclo[13.2.2]nonadeca-1(17),15,18-triene-9,1'-cyclopentane]-5,8,11-trione
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C30H40N4O3
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1
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| 1 |
Ki > 10000 nM
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CP0883294
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(8S,17S)-17-benzyl-8-isobutyl-12-oxa-6,9,15,18-tetraazaspiro[4.14]nonadecane-7,16,19-trione
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C25H38N4O4
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1
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| 1 |
Ki > 10000 nM
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CP0883360
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(5S,11R)-7,11-dimethyl-5-propyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C22H34N4O4
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1
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| 1 |
Ki > 10000 nM
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CP0893996
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(5S,11S)-5-(4-aminobutyl)-11-benzyl-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C32H45N5O4
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1
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| 1 |
Ki > 10000 nM
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CP0893997
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3-((5S,8R,11R)-11-benzyl-6,9,12-trioxo-5-propyl-3,4,5,6,7,8,9,10,11,12,13,14,15,16-tetradecahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecin-8-yl)propanoic acid
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C30H40N4O6
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1
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| 1 |
Ki > 10000 nM
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CP0901795
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(1R,5R,11S,14S)-5-benzyl-9-methyl-11-propyl-17-oxa-3,6,9,12-tetraazabicyclo[12.2.1]heptadecane-4,7,10-trione
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C23H34N4O4
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1
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| 1 |
Ki > 10000 nM
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CP0901817
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(8S,18S)-18-benzyl-8-isobutyl-6,9,16,19-tetraazaspiro[4.15]icos-12-ene-7,17,20-trione
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C27H40N4O3
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1
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| 1 |
Ki > 10000 nM
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CP0901820
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(3R,6R,9S)-3-benzyl-9-sec-butyl-6,7-dimethyl-1,4,7,10-tetraazacycloheptadec-15-ene-2,5,8-trione
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C26H40N4O3
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1
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| 1 |
Ki > 10000 nM
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CP0901821
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(3R,6R,9S)-3-benzyl-9-sec-butyl-6,7-dimethyl-1,4,7,10-tetraazacyclooctadec-15-ene-2,5,8-trione
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C27H42N4O3
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1
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| 1 |
Ki > 10000 nM
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CP0901822
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(5S,8R,11R)-11-benzyl-5-sec-butyl-7,8-dimethyl-6,9,12-trioxo-3,4,5,6,7,8,9,10,11,12,13,14,15,16-tetradecahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-18-carboximidamide
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C31H44N6O4
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1
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| 1 |
Ki > 10000 nM
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CP0902762
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(5S,8R,11R)-8-(4-aminobutyl)-11-benzyl-5-propyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C31H45N5O4
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1
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| 1 |
Ki > 10000 nM
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CP0903685
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(5S,11S)-11-ethyl-5-isobutyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C27H40N4O4
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1
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| 1 |
Ki > 10000 nM
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CP0906150
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(5R,11S)-5-Benzyl-9-methyl-11-propyl-15lambda(4)-thia-3,6,9,12,17-pentaaza-bicyclo[12.2.1]heptadeca-1(16),14-diene-4,7,10-trione
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C22H29N5O3S
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1
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| 1 |
Ki > 10000 nM
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CP0906151
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3-((5S,11S)-5-isobutyl-6,9,12-trioxo-2,3,4,5,6,7,9,10,11,12,13,14,15,16-tetradecahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-11-yl)propanoic acid
Show/Hide
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C28H42N4O6
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1
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| 1 |
Ki > 10000 nM
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CP0906181
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(8S,18S)-18-benzyl-8-isobutyl-6,9,16,19-tetraazaspiro[4.15]icos-12-yne-7,17,20-trione
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C27H38N4O3
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1
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| 1 |
Ki > 10000 nM
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CP0911458
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(5S,8R,11R)-4-acetyl-11-benzyl-7,8-dimethyl-5-propyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C31H42N4O5
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1
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| 1 |
Ki > 10000 nM
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CP0913556
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(5S,11S)-11-benzyl-5-isopropyl-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,4'-piperidine]-6,9,12(7H)-trione
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C31H43N5O4
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1
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| 1 |
Ki > 10000 nM
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CP0913560
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(3R,9S)-3-Benzyl-7-methyl-9-propyl-1,4,7,10-tetraaza-cyclohexadec-13-yne-2,5,8-trione
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C23H32N4O3
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1
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| 1 |
Ki > 10000 nM
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CP0913581
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5-isobutyl-11-(pyridin-4-ylmethyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C31H41N5O4
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1
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| 1 |
Ki > 10000 nM
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CP0915637
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(5R,11R)-11-benzyl-5-isobutyl-2,3,4,5,10,11,13,14,15,16-decahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C32H44N4O4
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1
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| 1 |
Ki > 10000 nM
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CP0915652
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(5S,11S)-5-isobutyl-11-propyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C28H42N4O4
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1
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| 1 |
Ki > 10000 nM
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CP0919531
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(5S,11S)-5-benzhydryl-11-benzyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C41H44N4O4
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1
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| 1 |
Ki > 10000 nM
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CP0924061
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(2S,3aR,6R,20S)-6-benzyl-20-sec-butyl-2-hydroxy-3,3a,5,6,8,9,10,11,17,18,19,20-dodecahydro-1H-benzo[q]pyrrolo[1,2-g][1,4,7,10,13]oxatetraazacyclooctadecine-4,7,21(2H)-trione
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C31H42N4O5
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1
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| 1 |
Ki > 10000 nM
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CP0945397
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(6S,12S)-6-benzyl-12-isobutyl-spiro[4,7,10,13-tetrazabicyclo[13.3.1]nonadeca-1(18),15(19),16-triene-9,1'-cyclopentane]-5,8,11-trione
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C30H40N4O3
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1
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| 1 |
Ki > 10000 nM
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CP0950235
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3-((5S,11S)-5-isobutyl-6,9,12-trioxo-2,3,4,5,6,7,9,10,11,12,13,14-dodecahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-11-yl)propanoic acid
Show/Hide
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C28H40N4O6
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1
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| 1 |
Ki > 10000 nM
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CP0960126
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(5S,11S)-11-benzyl-5-(biphenyl-4-ylmethyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C41H44N4O4
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1
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| 1 |
Ki > 10000 nM
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CP0508619
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2-(5-methoxypyridin-2-yl)-1-[2-[(1R)-1-(4-pyrimidin-2-ylphenyl)ethyl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
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C27H31N5O2
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1
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| 1 |
Ki = 25118.86 nM
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CP0413166
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2-(5-ethylpyridin-2-yl)-1-[2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
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C30H35N5O
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1
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| 1 |
Ki > 50 nM
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CP0511171
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1-[2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]-2-(2H-pyrazolo[3,4-b]pyridin-3-yl)ethanone
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C29H31N7O
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1
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| 1 |
Ki > 50 nM
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CP0542185
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2-(1-ethylpyrazolo[3,4-b]pyridin-3-yl)-1-[2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
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C31H35N7O
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1
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| 1 |
Ki > 50 nM
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CP0848577
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(5S,11S)-5-sec-butyl-11-(hydroxymethyl)-7-methyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C27H40N4O5
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1
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| 1 |
Ki > 500 nM
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CP0864943
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(Z)-11-((1H-imidazol-4-yl)methyl)-5-isobutyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C29H40N6O4
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1
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| 1 |
Ki > 500 nM
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CP0873135
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5-sec-butyl-11-(hydroxymethyl)-7-methyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C27H40N4O5
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1
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| 1 |
Ki > 500 nM
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CP0873136
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5-sec-butyl-11-(methoxymethyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C27H40N4O5
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1
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| 1 |
Ki > 500 nM
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CP0875152
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(5S,11S)-11-((1H-imidazol-4-yl)methyl)-5-isobutyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C29H40N6O4
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1
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| 1 |
Ki > 500 nM
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CP0875193
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(5S,11S)-5-isobutyl-11-phenethyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C33H44N4O4
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1
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| 1 |
Ki > 500 nM
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CP0901769
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(5S,11S,Z)-5-sec-butyl-11-(methoxymethyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C27H40N4O5
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1
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| 1 |
Ki > 500 nM
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CP0864409
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(5S,8S,11R)-11-benzyl-5-sec-butyl-8-isobutyl-7-methyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C33H48N4O4
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1
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| 1 |
Ki > 1000 nM
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CP0864411
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(5S,11S)-5-isobutyl-11-(pyridin-3-ylmethyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C31H41N5O4
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1
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| 1 |
Ki > 1000 nM
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CP0867089
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(5S,11S)-11-benzhydryl-5-isobutyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C38H46N4O4
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1
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| 1 |
Ki > 1000 nM
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CP0869403
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(5S,11S)-5-isobutyl-11-(pyridin-2-ylmethyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C31H41N5O4
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1
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| 1 |
Ki > 1000 nM
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CP0875195
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5-isobutyl-11-(pyridin-3-ylmethyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
Show/Hide
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C31H41N5O4
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1
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| 1 |
Ki > 1000 nM
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CP0883376
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(5S,11S)-11-benzyl-5-isopropyl-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,4'-piperidine]-6,9,12(7H)-trione
Show/Hide
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C31H41N5O4
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1
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| 1 |
Ki > 1000 nM
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CP0894001
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11-benzyl-5-sec-butyl-7-methyl-8-propyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C32H46N4O4
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1
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| 1 |
Ki > 1000 nM
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CP0894003
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(4S,7R,10R)-10-benzyl-4-sec-butyl-6,7-dimethyl-1,2,3,4,6,7,9,10,13,14-decahydrobenzo[m][1,4,7,10]tetraazacyclooctadecine-5,8,11(12H)-trione
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C31H42N4O3
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1
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| 1 |
Ki > 1000 nM
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CP0899614
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(5S,8S,11R)-11-benzyl-5-sec-butyl-7-methyl-8-propyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
Show/Hide
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C32H46N4O4
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1
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| 1 |
Ki > 1000 nM
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CP0901762
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(5S,8R,11R)-11-benzyl-5-sec-butyl-8-(thiazol-4-ylmethyl)-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C32H41N5O4S
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1
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| 1 |
Ki > 1000 nM
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CP0901768
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(5S,8R,11R)-11-benzyl-5-sec-butyl-8-(hydroxymethyl)-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C29H40N4O5
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1
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| 1 |
Ki > 1000 nM
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CP0906182
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(5R,8R,11R)-11-benzyl-5-sec-butyl-8-isobutyl-7-methyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C33H48N4O4
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1
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| 1 |
Ki > 1000 nM
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CP0921117
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(5S,11S)-11-benzyl-5-(pyridin-2-ylmethyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C34H39N5O4
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1
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| 1 |
Ki > 1000 nM
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CP0952679
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5-isobutyl-11-(pyridin-2-ylmethyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C31H41N5O4
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1
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| 1 |
Ki > 1000 nM
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CP0955075
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11-benzyl-5-sec-butyl-8-isopropyl-7-methyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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C32H46N4O4
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1
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| 1 |
Ki > 1000 nM
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CP0959549
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(5S,11S)-11-benzyl-5-(pyridin-4-ylmethyl)-2,3,4,5,10,11,13,14-octahydrospiro[benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-8,1'-cyclopentane]-6,9,12(7H)-trione
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C34H39N5O4
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1
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| 1 |
Ki > 1000 nM
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CP0379666
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2-(5-methoxypyridin-2-yl)-1-[2-[(1S)-2-methyl-1-(4-pyrimidin-2-ylphenyl)propyl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
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C29H35N5O2
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1
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| 1 |
Ki < 20892.96 nM
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CP0487377
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2-(5-methoxypyridin-2-yl)-1-[2-[(1R)-2-methyl-1-(4-pyrimidin-2-ylphenyl)propyl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
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C29H35N5O2
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1
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| 1 |
Ki < 29512.09 nM
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CP0487378
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2-(5-methoxypyridin-2-yl)-1-[2-[2-methyl-1-(4-pyrimidin-2-ylphenyl)propyl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
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C29H35N5O2
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1
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| 1 |
Ki < 30199.52 nM
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