General Information of the Compound
Compound ID
CP0915635
Compound Name
(2R,5S,8R,11R)-11-benzyl-5-cyclopropyl-19-fluoro-2,7,8-trimethyl-4,5,7,8,10,11,13,14,15,16-decahydro-2H-benzo[q][1,4,7,10,13]oxatetraazacyclooctadecine-6,9,12(3H)-trione
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Structure
Formula
C30H39FN4O4
Molecular Weight
538.664
Canonical SMILES
C[C@@H]1CN[C@@H](C2CC2)C(=O)N(C)[C@H](C)C(=O)N[C@H](Cc2ccccc2)C(=O)NCCCc2ccc(F)cc2O1
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InChI
InChI=1S/C30H39FN4O4/c1-19-18-33-27(23-11-12-23)30(38)35(3)20(2)28(36)34-25(16-21-8-5-4-6-9-21)29(37)32-15-7-10-22-13-14-24(31)17-26(22)39-19/h4-6,8-9,13-14,17,19-20,23,25,27,33H,7,10-12,15-16,18H2,1-3H3,(H,32,37)(H,34,36)/t19-,20-,25-,27+/m1/s1
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InChIKey
FSBQWWFVZJJRPA-ABNZCKJZSA-N
Physicochemical Property
logP
2.598
Rotatable Bonds
3
Heavy Atom Count
39
Polar Areas
99.77
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
5
Complexity
39

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 24969783
SID: 56267926
ChEMBL ID
CHEMBL3909838
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01155, Growth hormone secretagogue receptor type 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 10 nM
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   LI
   LO
   TS