General Information of the Compound
Compound ID
CP0867097
Compound Name
CHEMBL3955179
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Structure
Formula
C32H39ClN4O4
Molecular Weight
579.141
Canonical SMILES
O=C1NC/C=C\c2ccccc2OCCNC2(CCCC2)C(=O)NC2(CCCC2)C(=O)N[C@H]1Cc1cccc(Cl)c1
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InChI
InChI=1S/C32H39ClN4O4/c33-25-12-7-9-23(21-25)22-26-28(38)34-18-8-11-24-10-1-2-13-27(24)41-20-19-35-31(14-3-4-15-31)30(40)37-32(29(39)36-26)16-5-6-17-32/h1-2,7-13,21,26,35H,3-6,14-20,22H2,(H,34,38)(H,36,39)(H,37,40)/b11-8-/t26-/m0/s1
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InChIKey
MTGASXKPLWBSEL-HYMLKPMKSA-N
Physicochemical Property
logP
3.9207
Rotatable Bonds
2
Heavy Atom Count
41
Polar Areas
108.56
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
5
Complexity
41

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 134143746
ChEMBL ID
CHEMBL3955179
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01155, Growth hormone secretagogue receptor type 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 0.1 nM
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