General Information of the Protein
Protein ID
PT04664
Protein Name
Myc proto-oncogene protein
Secondarily
Protein Name
Class E basic helix-loop-helix protein 39
Proto-oncogene c-Myc
Transcription factor p64
Gene Name
MYC
Secondarily
Gene Name
BHLHE39
Sequence
MDFFRVVENQQPPATMPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTELLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPNPARGHSVCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKSCASQDSSAFSPSSDSLLSSTESSPQGSPEPLVLHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQAPGKRSESGSPSAGGHSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAKRVKLDSVRVLRQISNNRKCTSPRSSDTEENVKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAEEQKLISEEDLLRKRREQLKHKLEQLRNSCA
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Organism
Homo sapiens, Human
Protein Classification
Transcription factor
Function
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3' (PubMed:24940000, PubMed:25956029). Activates the transcription of growth-related genes (PubMed:24940000, PubMed:25956029). Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis (PubMed:24940000, PubMed:25956029). Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells (By similarity). Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). Positively regulates transcription of HNRNPA1, HNRNPA2 and PTBP1 which in turn regulate splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform (PubMed:20010808).
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Uniprot ID
Primary ID:
P01106

Secondarily ID:
A0A024R9L7
A0A087WUS5
A8WFE7
H0YBT0
P01107
Q14026
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Ensembl ID
ENSG00000136997
HGNC ID
HGNC:7553
Subcellular Location
Nucleus
Nucleoplasm
Nucleus
Nucleolus
Map of Molecular Bioactivity Related to the Protein
Map of Molecular Bioactivity Related to the Protein

Protein
Cell Line
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000025 , HEK-293T
 Cell Line Info 
Compound ID Compound Name Compound Formula
CP0874563
 Compound Info 
(Z)-5-((5-((6-acetyl-1H-benzo[d]imidazol-2-yl)thio)furan-2-yl)methylene)-3-isopropylthiazolidine-2,4-dione
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C20H17N3O4S2
  1
1
IC50 = 260 nM
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CP0887758
 Compound Info 
(Z)-3-isopropyl-5-((5-((6-nitro-1H-benzo[d]imidazol-2-yl)thio)furan-2-yl)methylene)thiazolidine-2,4-dione
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C18H14N4O5S2
  1
1
IC50 = 360 nM
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CP0957748
 Compound Info 
(Z)-N-(2-((5-((3-isopropyl-2,4-dioxothiazolidin-5-ylidene)methyl)furan-2-yl)thio)-1H-benzo[d]imidazol-6-yl)benzamide
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C25H20N4O4S2
  1
1
IC50 = 400 nM
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CP0942646
 Compound Info 
(Z)-3-isopropyl-5-((5-((6-(trifluoromethoxy)-1H-benzo[d]imidazol-2-yl)thio)furan-2-yl)methylene)thiazolidine-2,4-dione
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C19H14F3N3O4S2
  1
1
IC50 = 440 nM
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CP0961412
 Compound Info 
(Z)-5-((6-((1H-benzo[d]imidazol-2-yl)thio)benzofuran-2-yl)methylene)-3-isopropylthiazolidine-2,4-dione
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C22H17N3O3S2
  1
1
IC50 = 540 nM
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CP0957746
 Compound Info 
(Z)-5-((5-((5,6-dichloro-1H-benzo[d]imidazol-2-yl)thio)furan-2-yl)methylene)-3-isopropylthiazolidine-2,4-dione
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C18H13Cl2N3O3S2
  1
1
IC50 = 630 nM
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CP0942644
 Compound Info 
(Z)-3-isopropyl-5-((5-((6-isopropyl-1H-benzo[d]imidazol-2-yl)thio)furan-2-yl)methylene)thiazolidine-2,4-dione
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C21H21N3O3S2
  1
1
IC50 = 640 nM
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CP0957745
 Compound Info 
(Z)-3-isopropyl-5-((5-(6-(trifluoromethyl)-1H-benzo[d]imidazol-2-ylthio)furan-2-yl)methylene)thiazolidine-2,4-dione
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C19H14F3N3O3S2
  1
1
IC50 = 640 nM
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CP0949903
 Compound Info 
(Z)-5-((5-(1H-benzo[d]imidazol-2-ylthio)furan-2-yl)methylene)-3-isopropylthiazolidine-2,4-dione
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C18H15N3O3S2
  1
1
IC50 = 670 nM
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CP0970005
 Compound Info 
(Z)-5-((5-((6-chloro-1H-benzo[d]imidazol-2-yl)thio)furan-2-yl)methylene)-3-isopropylthiazolidine-2,4-dione
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C18H14ClN3O3S2
  1
1
IC50 = 790 nM
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CP0960866
 Compound Info 
(Z)-5-((5-((1H-benzo[d]imidazol-2-yl)thio)furan-2-yl)methylene)-3-isopropylimidazolidine-2,4-dione
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C18H16N4O3S
  1
1
IC50 = 830 nM
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CP0966771
 Compound Info 
(Z)-N-(2-(5-((3-isopropyl-2,4-dioxothiazolidin-5-ylidene)methyl)furan-2-ylthio)-1H-benzo[d]imidazol-6-yl)acetamide
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C20H18N4O4S2
  1
1
IC50 = 930 nM
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CP0909643
 Compound Info 
(Z)-5-((5-((7-chloro-1H-benzo[d]imidazol-2-yl)thio)furan-2-yl)methylene)-3-isopropylthiazolidine-2,4-dione
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C18H14ClN3O3S2
  1
1
IC50 = 980 nM
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CP0966772
 Compound Info 
(Z)-5-(3-((1H-benzo[d]imidazol-2-yl)oxy)benzylidene)-3-isopropylthiazolidine-2,4-dione
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C20H17N3O3S
  1
1
IC50 = 990 nM
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CP0946064
 Compound Info 
(Z)-5-((5-((6-chloro-1H-benzo[d]imidazol-2-yl)thio)furan-2-yl)methylene)-3-isopropylimidazolidine-2,4-dione
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C18H15ClN4O3S
  1
1
IC50 = 1050 nM
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CP0909640
 Compound Info 
(Z)-3-isopropyl-5-((5-((6-methoxy-1H-benzo[d]imidazol-2-yl)thio)furan-2-yl)methylene)thiazolidine-2,4-dione
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C19H17N3O4S2
  1
1
IC50 = 1190 nM
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CP0909641
 Compound Info 
(Z)-1-(3-(5-((5-((1H-benzo[d]imidazol-2-yl)thio)furan-2-yl)methylene)-2,4-dioxothiazolidin-3-yl)propyl)-3-phenylurea
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C25H21N5O4S2
  1
1
IC50 = 1220 nM
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CP0960877
 Compound Info 
(3aS,10bS)-3a-benzyl-2-phenyl-5-(2-(phenylsulfonyl)ethyl)-3a,5,6,10b-tetrahydro-4H-benzo[c]furo[2,3-e]azepin-4-one
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C33H29NO4S
  1
1
IC50 = 1250 nM
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CP0957749
 Compound Info 
(Z)-methyl 2-(5-((3-isopropyl-2,4-dioxothiazolidin-5-ylidene)methyl)furan-2-ylthio)-1H-benzo[d]imidazole-6-carboxylate
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C20H17N3O5S2
  1
1
IC50 = 1490 nM
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CP0960482
 Compound Info 
(Z)-3-isopropyl-5-((5-((7-methyl-1H-benzo[d]imidazol-2-yl)thio)furan-2-yl)methylene)thiazolidine-2,4-dione
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C19H17N3O3S2
  1
1
IC50 = 1500 nM
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CP0853200
 Compound Info 
(Z)-5-((5-((1H-benzo[d]imidazol-2-yl)thio)thiophen-2-yl)methylene)-3-isopropylthiazolidine-2,4-dione
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C18H15N3O2S3
  1
1
IC50 = 1620 nM
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CP0946324
 Compound Info 
(Z)-3-isopropyl-5-((5-((7-methoxy-1H-benzo[d]imidazol-2-yl)thio)furan-2-yl)methylene)thiazolidine-2,4-dione
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C19H17N3O4S2
  1
1
IC50 = 1630 nM
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CP0968352
 Compound Info 
(Z)-3-isopropyl-5-((5-(1-methyl-1H-benzo[d]imidazol-2-ylthio)furan-2-yl)methylene)thiazolidine-2,4-dione
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C19H17N3O3S2
  1
1
IC50 = 1670 nM
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CP0960869
 Compound Info 
(Z)-5-(4-((1H-benzo[d]imidazol-2-yl)thio)benzylidene)-3-isopropylthiazolidine-2,4-dione
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C20H17N3O2S2
  1
1
IC50 = 1820 nM
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CP0955484
 Compound Info 
(Z)-tert-butyl 2-(5-((5-((1H-benzo[d]imidazol-2-yl)thio)furan-2-yl)methylene)-2,4-dioxothiazolidin-3-yl)acetate
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C21H19N3O5S2
  1
1
IC50 = 1960 nM
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CP0964590
 Compound Info 
(3aS,10bS)-3a-benzyl-5-(2-hydroxyethyl)-2-phenyl-5,6-dihydro-3aH-benzo[e]oxazolo[4,5-c]azepin-4(10bH)-one
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C26H24N2O3
  1
1
IC50 = 2150 nM
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CP0853201
 Compound Info 
(Z)-5-((5-(1H-benzo[d]imidazol-2-ylthio)furan-2-yl)methylene)-3-sec-butylthiazolidine-2,4-dione
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C19H17N3O3S2
  1
1
IC50 = 2220 nM
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CP0966768
 Compound Info 
N-(3-((Z)-5-((5-((1H-benzo[d]imidazol-2-yl)thio)furan-2-yl)methylene)-2,4-dioxothiazolidin-3-yl)propyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide
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C28H30N6O5S3
  1
1
IC50 = 2280 nM
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CP0960880
 Compound Info 
(Z)-methyl 2-(5-((5-(1H-benzo[d]imidazol-2-ylthio)furan-2-yl)methylene)-2,4-dioxothiazolidin-3-yl)propanoate
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C19H15N3O5S2
  1
1
IC50 = 2770 nM
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CP0955485
 Compound Info 
(Z)-methyl 2-(5-((5-((1H-benzo[d]imidazol-2-yl)thio)furan-2-yl)methylene)-2,4-dioxothiazolidin-3-yl)acetate
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C18H13N3O5S2
  1
1
IC50 = 3260 nM
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CP0942645
 Compound Info 
5-(1H-benzo[d]imidazol-2-ylthio)-N-phenylfuran-2-carboxamide
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C18H13N3O2S
  1
1
IC50 = 3320 nM
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CP0887772
 Compound Info 
ethyl 2-((3aS,10bS)-3a-benzyl-4-oxo-2-phenyl-3aH-benzo[e]oxazolo[4,5-c]azepin-5(4H,6H,10bH)-yl)acetate
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C28H26N2O4
  1
1
IC50 = 3380 nM
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CP0887759
 Compound Info 
(Z)-5-((5-(6-amino-1H-benzo[d]imidazol-2-ylthio)furan-2-yl)methylene)-3-isopropylthiazolidine-2,4-dione
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C18H16N4O3S2
  1
1
IC50 = 4560 nM
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CP0955935
 Compound Info 
N-((5-((1H-benzo[d]imidazol-2-yl)thio)furan-2-yl)methyl)aniline
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C18H15N3OS
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1
IC50 = 4660 nM
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CP0946058
 Compound Info 
Methyl (4S,5S)-5-(2-(azidomethyl)phenyl)-4-benzyl-2-phenyl-4,5-dihydrooxazole-4-carboxylate
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C25H22N4O3
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1
IC50 = 4670 nM
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CP0864177
 Compound Info 
3-(4-((3aS,10bS)-3a-benzyl-4-oxo-5-(2-(phenylsulfonyl)ethyl)-4,5,6,10b-tetrahydro-3aH-benzo[e]oxazolo[4,5-c]azepin-2-yl)phenoxy)propyl acetate
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C37H36N2O7S
  1
1
IC50 = 4700 nM
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CP0887771
 Compound Info 
(3aS,10bS)-5-acetyl-3a-benzyl-2-phenyl-5,6-dihydro-3aH-benzo[e]oxazolo[4,5-c]azepin-4(10bH)-one
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C26H22N2O3
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1
IC50 = 4810 nM
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CP0951342
 Compound Info 
3-(4-((3aR,10bS)-3a-benzyl-5-(2-(phenylsulfonyl)ethyl)-4,5,6,10b-tetrahydro-3aH-benzo[e]oxazolo[4,5-c]azepin-2-yl)phenoxy)propyl 2-(2-(2-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)ethoxy)ethoxy)ethylcarbamate
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C52H64N6O10S2
  1
1
IC50 = 5380 nM
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CP0960868
 Compound Info 
(Z)-5-((5-((3H-imidazo[4,5-b]pyridin-2-yl)thio)furan-2-yl)methylene)thiazolidine-2,4-dione
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C14H8N4O3S2
  1
1
IC50 = 5600 nM
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CP0853199
 Compound Info 
(Z)-5-((5-(benzo[d]thiazol-2-ylthio)furan-2-yl)methylene)-3-isopropylthiazolidine-2,4-dione
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C18H14N2O3S3
  1
1
IC50 = 5720 nM
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CP0864176
 Compound Info 
(3aS,10bS)-3a-benzyl-8-chloro-2-phenyl-5-(2-(phenylsulfonyl)ethyl)-5,6-dihydro-3aH-benzo[e]oxazolo[4,5-c]azepin-4(10bH)-one
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C32H27ClN2O4S
  1
1
IC50 = 5940 nM
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CP0638986
 Compound Info 
(3aS,10bS)-3a-benzyl-2-phenyl-5-(2-(phenylsulfonyl)ethyl)-5,6-dihydro-3aH-benzo[e]oxazolo[4,5-c]azepin-4(10bH)-one
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C32H28N2O4S
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1
IC50 = 6190 nM
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CP0970006
 Compound Info 
(Z)-5-((5-(1H-benzo[d]imidazol-2-ylthio)furan-2-yl)methylene)-3-(3-aminopropyl)thiazolidine-2,4-dione 2,2,2-trifluoroacetate
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C20H17F3N4O5S2
  1
1
IC50 = 6520 nM
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CP0966767
 Compound Info 
(Z)-1-(3-(5-((5-(1H-benzo[d]imidazol-2-ylthio)furan-2-yl)methylene)-2,4-dioxothiazolidin-3-yl)propyl)-3-ethylurea
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C21H21N5O4S2
  1
1
IC50 = 6770 nM
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CP0853202
 Compound Info 
(Z)-5-((5-(1H-benzo[d]imidazol-2-ylthio)furan-2-yl)methylene)-3-(2-oxo-2-(4-phenylpiperazin-1-yl)ethyl)thiazolidine-2,4-dione
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C27H23N5O4S2
  1
1
IC50 = 7010 nM
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CP0955933
 Compound Info 
(Z)-5-((5-((1H-benzo[d]imidazol-2-yl)thio)furan-2-yl)methylene)imidazolidine-2,4-dione
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C15H10N4O3S
  1
1
IC50 = 7500 nM
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CP0964589
 Compound Info 
(3aS,10bS)-5-allyl-3a-benzyl-2-phenyl-5,6-dihydro-3aH-benzo[e]oxazolo[4,5-c]azepin-4(10bH)-one
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C27H24N2O2
  1
1
IC50 = 7670 nM
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CP0966766
 Compound Info 
(Z)-3-isopropyl-5-((5-(pyridin-2-ylthio)furan-2-yl)methylene)thiazolidine-2,4-dione
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C16H14N2O3S2
  1
1
IC50 = 7670 nM
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CP0966765
 Compound Info 
(3aS,10bS)-3a,5-dibenzyl-2-(4-(3-hydroxypropoxy)phenyl)-5,6-dihydro-3aH-benzo[e]oxazolo[4,5-c]azepin-4(10bH)-one
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C34H32N2O4
  1
1
IC50 = 7880 nM
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CP0970007
 Compound Info 
5-((1H-benzo[d]imidazol-2-yl)thio)-N-isopropylfuran-2-carboxamide
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C15H15N3O2S
  1
1
IC50 = 7900 nM
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CP0968212
 Compound Info 
(E)-3-((5-((1H-benzo[d]imidazol-2-yl)thio)furan-2-yl)methylene)pyrrolidine-2,5-dione
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C16H11N3O3S
  1
1
IC50 = 9020 nM
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CP0887774
 Compound Info 
(3aS,10bS)-3a-benzyl-2-(4-(3-hydroxypropoxy)phenyl)-5,6-dihydro-3aH-benzo[e]oxazolo[4,5-c]azepin-4(10bH)-one
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C27H26N2O4
  1
1
IC50 = 9340 nM
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CP0969652
 Compound Info 
(Z)-5-((5-(benzo[d]oxazol-2-ylthio)furan-2-yl)methylene)-3-isopropylthiazolidine-2,4-dione
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C18H14N2O4S2
  1
1
IC50 = 9390 nM
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CP0951343
 Compound Info 
2-((3aS,10bS)-3a-benzyl-4-oxo-2-phenyl-3aH-benzo[e]oxazolo[4,5-c]azepin-5(4H,6H,10bH)-yl)-N-(prop-2-ynyl)acetamide
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C29H25N3O3
  1
1
IC50 = 10140 nM
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CP0960483
 Compound Info 
2-((5-((4-ethylpiperazin-1-yl)methyl)furan-2-yl)thio)-1H-benzo[d]imidazole
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C18H22N4OS
  1
1
IC50 = 10230 nM
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CP0887770
 Compound Info 
(3aS,10bS)-3a-benzyl-2-phenyl-3a,5,6,10b-tetrahydro-4H-benzo[c]furo[2,3-e]azepin-4-one
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C25H21NO2
  1
1
IC50 = 11340 nM
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CP0966769
 Compound Info 
(Z)-5-((5-(1H-benzo[d]imidazol-2-ylthio)furan-2-yl)methylene)-3-phenylthiazolidine-2,4-dione
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C21H13N3O3S2
  1
1
IC50 = 11900 nM
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CP0968321
 Compound Info 
(3aS,10bS)-3a-benzyl-2-phenyl-5,6-dihydro-3aH-benzo[e]oxazolo[4,5-c]azepin-4(10bH)-one
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C24H20N2O2
  1
1
IC50 = 16760 nM
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CP0966764
 Compound Info 
(3aS,10bS)-5-benzoyl-3a-benzyl-2-phenyl-5,6-dihydro-3aH-benzo[e]oxazolo[4,5-c]azepin-4(10bH)-one
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C31H24N2O3
  1
1
IC50 = 17200 nM
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CP0961429
 Compound Info 
N-(2-(2-(2-((3aS,10bS)-3a-benzyl-4-oxo-2-phenyl-3aH-benzo[e]oxazolo[4,5-c]azepin-5(4H,6H,10bH)-yl)acetamido)ethylamino)-2-oxoethyl)-3-(3-methyl-3H-diazirin-3-yl)-N-(prop-2-ynyl)propanamide
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C38H39N7O5
  1
1
IC50 = 18730 nM
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CP0941901
 Compound Info 
(Z)-5-((5-(1H-imidazol-2-ylthio)furan-2-yl)methylene)-3-isopropylthiazolidine-2,4-dione
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C14H13N3O3S2
  1
1
IC50 = 20800 nM
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CP0882332
 Compound Info 
(3-((2-((7-Nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)benzamido)methyl)phenyl)boronic acid
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C20H16BN5O6
  1
1
IC50 = 24000 nM
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CP0946337
 Compound Info 
1,3-dimethyl-5-((5-(1-methyl-1H-benzo[d]imidazol-2-ylthio)furan-2-yl)methylene)pyrimidine-2,4,6(1H,3H,5H)-trione
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C19H16N4O4S
  1
1
IC50 = 26810 nM
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CP0853205
 Compound Info 
3-((5-((1H-benzo[d]imidazol-2-yl)thio)furan-2-yl)methyl)thiazolidine-2,4-dione
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C15H11N3O3S2
  1
1
IC50 = 29970 nM
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CP0010755
 Compound Info 
(5Z)-5-[(4-ethylphenyl)methylidene]-1,3-thiazolidine-2,4-dione
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C12H11NO2S
  1
1
IC50 > 30000 nM
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CP0849810
 Compound Info 
(1R,2S,4S,5S,6R)-N-(2-((5Z)-5-(4-Ethylbenzylidene)-2,4-dioxothiazolidin-3-yl)ethyl)-5,6-dihydroxybicyclo[2.2.1]heptane-2-carboxamide
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C22H26N2O5S
  1
1
IC50 > 30000 nM
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CP0894454
 Compound Info 
2-((7-Nitrobenzo[c] [1,2,5]oxadiazol-4-yl)amino)benzamide
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C13H9N5O4
  1
1
IC50 > 30000 nM
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CP0938226
 Compound Info 
(1S,2S,4S)-N-(2-((5Z)-5-(4-Ethylbenzylidene)-2,4-dioxothiazolidin-3-yl)ethyl)bicyclo[2.2.1]hept-5-ene-2-carboxamide
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C22H24N2O3S
  1
1
IC50 > 30000 nM
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CP0953330
 Compound Info 
(Z)-3-(2-((1R,2R,4R,5S,6R)-5,6-Dihydroxybicyclo[2.2.1]heptane-2-yl)ethyl)-5-(4-ethylbenzylidene)thiazolidine-2,4-dione
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C21H25NO4S
  1
1
IC50 > 30000 nM
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CP0957165
 Compound Info 
(4-((2-((7-Nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)benzamido)methyl)phenyl)boronic acid
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C20H16BN5O6
  1
1
IC50 > 30000 nM
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CP0965278
 Compound Info 
(Z)-3-(2-((1S,2S,4S)-Bicyclo[2.2.1]hept-5-en-2-yl)ethyl)-5-(4-ethylbenzylidene)thiazolidine-2,4-dione
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C21H23NO2S
  1
1
IC50 > 30000 nM
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CP0946067
 Compound Info 
4-((5-(1H-benzo[d]imidazol-2-ylthio)furan-2-yl)methyl)morpholine
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C16H17N3O2S
  1
1
IC50 = 32900 nM
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CP0909642
 Compound Info 
sodium (Z)-2-(5-((5-(1H-benzo[d]imidazol-2-ylthio)furan-2-yl)methylene)-2,4-dioxothiazolidin-3-yl)acetate
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C17H10N3NaO5S2
  1
1
IC50 = 33650 nM
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CP0946066
 Compound Info 
(5-((1H-benzo[d]imidazol-2-yl)thio)furan-2-yl)methanol
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C12H10N2O2S
  1
1
IC50 > 40000 nM
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CP0960481
 Compound Info 
(Z)-5-((5-(1H-benzo[d]imidazol-2-yl)furan-2-yl)methylene)-3-isopropylthiazolidine-2,4-dione
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C18H15N3O3S
  1
1
IC50 > 40000 nM
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CP0887773
 Compound Info 
2-((3aS,10bS)-3a-benzyl-4-oxo-2-phenyl-3aH-benzo[e]oxazolo[4,5-c]azepin-5(4H,6H,10bH)-yl)acetic acid
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C26H22N2O4
  1
1
IC50 > 50000 nM
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CP0969646
 Compound Info 
(3aS,10bS)-2-phenyl-5,6-dihydro-3aH-benzo[e]oxazolo[4,5-c]azepin-4(10bH)-one
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C17H14N2O2
  1
1
IC50 > 50000 nM
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CP0954996
 Compound Info 
N-((5-(1H-benzo[d]imidazol-2-ylthio)furan-2-yl)methyl)propan-2-amine
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C15H17N3OS
  1
1
IC50 = 57470 nM
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CP0966770
 Compound Info 
1-(5-((1H-benzo[d]imidazol-2-yl)thio)furan-2-yl)-N,N-dimethylmethanamine
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C14H15N3OS
  1
1
IC50 = 59370 nM
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CP0946068
 Compound Info 
methyl 2-(((5-(1H-benzo[d]imidazol-2-yl)thio)furan-2-yl)methylamino)acetate
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C15H15N3O3S
  1
1
IC50 = 75900 nM
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CP0946065
 Compound Info 
methyl 2-((Z)-5-((E)-3-(furan-2-yl)allylidene)-2,4-dioxothiazolidin-3-yl)propanoate
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C14H13NO5S
  1
1
IC50 > 100000 nM
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CP0961411
 Compound Info 
(Z)-3-isopropyl-5-((5-methylfuran-2-yl)methylene)thiazolidine-2,4-dione
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C12H13NO3S
  1
1
IC50 > 100000 nM
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CP0968327
 Compound Info 
(Z)-3-isopropyl-5-((5-(p-tolylthio)furan-2-yl)methylene)thiazolidine-2,4-dione
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C18H17NO3S2
  1
1
IC50 > 100000 nM
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CP0968354
 Compound Info 
(Z)-3-isopropyl-5-((E)-2-methyl-3-phenylallylidene)thiazolidine-2,4-dione
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C16H17NO2S
  1
1
IC50 > 100000 nM
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Clinical Information about the Protein
Target 1 ( Myc messenger RNA (MYC mRNA) )
Target Type Clinical trial Target
Target 2 ( Proto-oncogene c-Myc (MYC) )
Target Type Literature-reported Target