General Information of the Compound
Compound ID
CP0849810
Compound Name
(1R,2S,4S,5S,6R)-N-(2-((5Z)-5-(4-Ethylbenzylidene)-2,4-dioxothiazolidin-3-yl)ethyl)-5,6-dihydroxybicyclo[2.2.1]heptane-2-carboxamide
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Structure
Formula
C22H26N2O5S
Molecular Weight
430.526
Canonical SMILES
CCc1ccc(/C=C2\SC(=O)N(CCNC(=O)[C@H]3C[C@@H]4C[C@H]3[C@@H](O)[C@H]4O)C2=O)cc1
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InChI
InChI=1S/C22H26N2O5S/c1-2-12-3-5-13(6-4-12)9-17-21(28)24(22(29)30-17)8-7-23-20(27)16-11-14-10-15(16)19(26)18(14)25/h3-6,9,14-16,18-19,25-26H,2,7-8,10-11H2,1H3,(H,23,27)/b17-9-/t14-,15+,16-,18-,19+/m0/s1
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InChIKey
ASOQKZPGBLSXSN-BGFIBISZSA-N
Physicochemical Property
logP
1.7793
Rotatable Bonds
6
Heavy Atom Count
30
Polar Areas
106.94
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
6
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 122417816
ChEMBL ID
CHEMBL4549582
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT04664, Myc proto-oncogene protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
IC50 > 30000 nM
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