General Information of the Compound
Compound ID
CP0887772
Compound Name
ethyl 2-((3aS,10bS)-3a-benzyl-4-oxo-2-phenyl-3aH-benzo[e]oxazolo[4,5-c]azepin-5(4H,6H,10bH)-yl)acetate
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Structure
Formula
C28H26N2O4
Molecular Weight
454.526
Canonical SMILES
CCOC(=O)CN1Cc2ccccc2[C@@H]2OC(c3ccccc3)=N[C@]2(Cc2ccccc2)C1=O
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InChI
InChI=1S/C28H26N2O4/c1-2-33-24(31)19-30-18-22-15-9-10-16-23(22)25-28(27(30)32,17-20-11-5-3-6-12-20)29-26(34-25)21-13-7-4-8-14-21/h3-16,25H,2,17-19H2,1H3/t25-,28-/m0/s1
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InChIKey
PKJUQWSLBMUTAC-LSYYVWMOSA-N
Physicochemical Property
logP
4.0915
Rotatable Bonds
6
Heavy Atom Count
34
Polar Areas
68.2
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
5
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 130334802
ChEMBL ID
CHEMBL4459646
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT04664, Myc proto-oncogene protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
IC50 = 3380 nM
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