General Information of the Compound
Compound ID
CP0955484
Compound Name
(Z)-tert-butyl 2-(5-((5-((1H-benzo[d]imidazol-2-yl)thio)furan-2-yl)methylene)-2,4-dioxothiazolidin-3-yl)acetate
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Structure
Formula
C21H19N3O5S2
Molecular Weight
457.533
Canonical SMILES
CC(C)(C)OC(=O)CN1C(=O)S/C(=C\c2ccc(Sc3nc4ccccc4[nH]3)o2)C1=O
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InChI
InChI=1S/C21H19N3O5S2/c1-21(2,3)29-16(25)11-24-18(26)15(30-20(24)27)10-12-8-9-17(28-12)31-19-22-13-6-4-5-7-14(13)23-19/h4-10H,11H2,1-3H3,(H,22,23)/b15-10-
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InChIKey
HYZPHHWSAVCHMU-GDNBJRDFSA-N
Physicochemical Property
logP
4.6851
Rotatable Bonds
5
Heavy Atom Count
31
Polar Areas
105.5
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
8
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 121395625
ChEMBL ID
CHEMBL4473626
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT04664, Myc proto-oncogene protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
IC50 = 1960 nM
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