General Information of the Compound
Compound ID
CP0961429
Compound Name
N-(2-(2-(2-((3aS,10bS)-3a-benzyl-4-oxo-2-phenyl-3aH-benzo[e]oxazolo[4,5-c]azepin-5(4H,6H,10bH)-yl)acetamido)ethylamino)-2-oxoethyl)-3-(3-methyl-3H-diazirin-3-yl)-N-(prop-2-ynyl)propanamide
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Structure
Formula
C38H39N7O5
Molecular Weight
673.774
Canonical SMILES
C#CCN(CC(=O)NCCNC(=O)CN1Cc2ccccc2[C@@H]2OC(c3ccccc3)=N[C@]2(Cc2ccccc2)C1=O)C(=O)CCC1(C)N=N1
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InChI
InChI=1S/C38H39N7O5/c1-3-22-44(33(48)18-19-37(2)42-43-37)25-31(46)39-20-21-40-32(47)26-45-24-29-16-10-11-17-30(29)34-38(36(45)49,23-27-12-6-4-7-13-27)41-35(50-34)28-14-8-5-9-15-28/h1,4-17,34H,18-26H2,2H3,(H,39,46)(H,40,47)/t34-,38-/m0/s1
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InChIKey
UBBDRMRCYYMYHT-UVNLRBHVSA-N
Physicochemical Property
logP
3.1848
Rotatable Bonds
14
Heavy Atom Count
50
Polar Areas
145.13
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
8
Complexity
50

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 155515656
ChEMBL ID
CHEMBL4442285
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT04664, Myc proto-oncogene protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
IC50 = 18730 nM
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