General Information of the Compound
Compound ID
CP0882332
Compound Name
(3-((2-((7-Nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)benzamido)methyl)phenyl)boronic acid
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Structure
Formula
C20H16BN5O6
Molecular Weight
433.189
Canonical SMILES
O=C(NCc1cccc(B(O)O)c1)c1ccccc1Nc1ccc([N+](=O)[O-])c2nonc12
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InChI
InChI=1S/C20H16BN5O6/c27-20(22-11-12-4-3-5-13(10-12)21(28)29)14-6-1-2-7-15(14)23-16-8-9-17(26(30)31)19-18(16)24-32-25-19/h1-10,23,28-29H,11H2,(H,22,27)
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InChIKey
DLCHXENQPCKSRP-UHFFFAOYSA-N
Physicochemical Property
logP
1.4844
Rotatable Bonds
7
Heavy Atom Count
32
Polar Areas
163.65
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
9
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 145124374
ChEMBL ID
CHEMBL4560104
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT04664, Myc proto-oncogene protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
IC50 = 24000 nM
   TI
   LI
   LO
   TS
Cell Viability or Cytotoxicity Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000002 K-562 Homo sapiens (Human)  1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CL000091 MV4-11 Homo sapiens (Human)  1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS