General Information of the Compound
Compound ID
CP0966768
Compound Name
N-(3-((Z)-5-((5-((1H-benzo[d]imidazol-2-yl)thio)furan-2-yl)methylene)-2,4-dioxothiazolidin-3-yl)propyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide
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Structure
Formula
C28H30N6O5S3
Molecular Weight
626.786
Canonical SMILES
O=C(CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21)NCCCN1C(=O)S/C(=C\c2ccc(Sc3nc4ccccc4[nH]3)o2)C1=O
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InChI
InChI=1S/C28H30N6O5S3/c35-22(9-4-3-8-20-24-19(15-40-20)30-26(37)33-24)29-12-5-13-34-25(36)21(41-28(34)38)14-16-10-11-23(39-16)42-27-31-17-6-1-2-7-18(17)32-27/h1-2,6-7,10-11,14,19-20,24H,3-5,8-9,12-13,15H2,(H,29,35)(H,31,32)(H2,30,33,37)/b21-14-/t19-,20-,24-/m0/s1
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InChIKey
YHEZJDRNSJAKFT-WIQGMPOSSA-N
Physicochemical Property
logP
4.5755
Rotatable Bonds
12
Heavy Atom Count
42
Polar Areas
149.43
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
9
Complexity
42

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 155520257
ChEMBL ID
CHEMBL4448869
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT04664, Myc proto-oncogene protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
IC50 = 2280 nM
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