General Information of the Compound
Compound ID
CP0966765
Compound Name
(3aS,10bS)-3a,5-dibenzyl-2-(4-(3-hydroxypropoxy)phenyl)-5,6-dihydro-3aH-benzo[e]oxazolo[4,5-c]azepin-4(10bH)-one
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Structure
Formula
C34H32N2O4
Molecular Weight
532.64
Canonical SMILES
O=C1N(Cc2ccccc2)Cc2ccccc2[C@@H]2OC(c3ccc(OCCCO)cc3)=N[C@]12Cc1ccccc1
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InChI
InChI=1S/C34H32N2O4/c37-20-9-21-39-29-18-16-27(17-19-29)32-35-34(22-25-10-3-1-4-11-25)31(40-32)30-15-8-7-14-28(30)24-36(33(34)38)23-26-12-5-2-6-13-26/h1-8,10-19,31,37H,9,20-24H2/t31-,34-/m0/s1
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InChIKey
USQDBZLQTBWLEQ-VBTAUBHQSA-N
Physicochemical Property
logP
5.4898
Rotatable Bonds
9
Heavy Atom Count
40
Polar Areas
71.36
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
40

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 24868698
ChEMBL ID
CHEMBL4588488
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT04664, Myc proto-oncogene protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
IC50 = 7880 nM
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