| Compound ID |
Compound Name |
Compound Formula |
|
CP0543722
|
3-(4-chlorophenyl)-N-[4-(2-morpholin-4-ylethyl)phenyl]-4-oxophthalazine-1-carboxamide
Show/Hide
|
C27H25ClN4O3
|
8
|
| 1 |
EC50 = 65.31 nM
|
|
|
| 2 |
IC50 = 2410 nM
|
|
|
| 3 |
IC50 = 2460 nM
|
|
|
| 4 |
IC50 = 3150 nM
|
|
|
| 5 |
IC50 = 4310 nM
|
|
|
| 6 |
IC50 = 6620 nM
|
|
|
| 7 |
IC50 = 14270 nM
|
|
|
| 8 |
IC50 = 83680 nM
|
|
|
|
CP0389820
|
N-(4-tert-butylphenyl)-2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]benzamide
Show/Hide
|
C33H39N5O4
|
14
|
| 1 |
EC50 = 252.6 nM
|
|
|
| 2 |
IC50 = 1260 nM
|
|
|
| 3 |
IC50 = 1270 nM
|
|
|
| 4 |
IC50 = 3330 nM
|
|
|
| 5 |
IC50 = 4330 nM
|
|
|
| 6 |
IC50 = 6020 nM
|
|
|
| 7 |
IC50 = 6320 nM
|
|
|
| 8 |
IC50 = 10320 nM
|
|
|
| 9 |
IC50 = 12520 nM
|
|
|
| 10 |
IC50 = 17210 nM
|
|
|
| 11 |
IC50 = 18390 nM
|
|
|
| 12 |
IC50 = 34900 nM
|
|
|
| 13 |
IC50 = 37180 nM
|
|
|
| 14 |
IC50 = 37210 nM
|
|
|
|
CP0444582
|
N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-3-[[4-(furan-2-yl)pyrimidin-2-yl]amino]-4-methylbenzamide
Show/Hide
|
C29H31N5O4
|
10
|
| 1 |
EC50 = 1190 nM
|
|
|
| 2 |
IC50 = 180 nM
|
|
|
| 3 |
IC50 = 420 nM
|
|
|
| 4 |
IC50 = 4880 nM
|
|
|
| 5 |
IC50 = 16920 nM
|
|
|
| 6 |
IC50 = 25680 nM
|
|
|
| 7 |
IC50 = 38970 nM
|
|
|
| 8 |
IC50 = 45320 nM
|
|
|
| 9 |
IC50 = 76830 nM
|
|
|
| 10 |
IC50 = 84320 nM
|
|
|
|
CP0116921
|
1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tetrahydro-2-isoquinolinyl)ethyl]phenyl}-4,5-dimethoxy-2-(3-quinolylcarboxamido)benzamide
Show/Hide
|
C38H38N4O6
|
7
|
| 1 |
IC50 = 460 nM
|
|
|
| 2 |
IC50 = 1600 nM
|
|
|
| 3 |
IC50 = 1970 nM
|
|
|
| 4 |
IC50 = 3020 nM
|
|
|
| 5 |
IC50 = 4970 nM
|
|
|
| 6 |
IC50 = 8280 nM
|
|
|
| 7 |
IC50 = 14390 nM
|
|
|
|
CP0002778
|
4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
Show/Hide
|
C29H31N7O
|
1
|
| 1 |
IC50 = 580 nM
|
|
|
|
CP0531428
|
N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-3-[[4-(2-hydroxyphenyl)pyrimidin-2-yl]amino]-4-methylbenzamide
Show/Hide
|
C31H33N5O4
|
1
|
| 1 |
IC50 = 920 nM
|
|
|
|
CP0451088
|
N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-4-methyl-3-[(4-thiophen-2-ylpyrimidin-2-yl)amino]benzamide
Show/Hide
|
C29H31N5O3S
|
1
|
| 1 |
IC50 = 940 nM
|
|
|
|
CP0547994
|
N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-4-methyl-3-[(4-phenylpyrimidin-2-yl)amino]benzamide
Show/Hide
|
C37H37N5O3
|
1
|
| 1 |
IC50 = 1030 nM
|
|
|
|
CP0419245
|
N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-3-[[4-(3-hydroxyphenyl)pyrimidin-2-yl]amino]-4-methylbenzamide
Show/Hide
|
C37H37N5O4
|
1
|
| 1 |
IC50 = 1050 nM
|
|
|
|
CP0553197
|
N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-4-methyl-3-[[4-(4-methylphenyl)pyrimidin-2-yl]amino]benzamide
Show/Hide
|
C32H35N5O3
|
1
|
| 1 |
IC50 = 1180 nM
|
|
|
|
CP0534059
|
N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-4-methyl-3-[(4-pyridin-2-ylpyrimidin-2-yl)amino]benzamide
Show/Hide
|
C36H36N6O3
|
1
|
| 1 |
IC50 = 1220 nM
|
|
|
|
CP0532221
|
N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-3-[[4-(4-methoxyphenyl)pyrimidin-2-yl]amino]-4-methylbenzamide
Show/Hide
|
C32H35N5O4
|
1
|
| 1 |
IC50 = 1770 nM
|
|
|
|
CP0547996
|
N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-4-methyl-3-[[4-(4-methylphenyl)pyrimidin-2-yl]amino]benzamide
Show/Hide
|
C38H39N5O3
|
1
|
| 1 |
IC50 = 1950 nM
|
|
|
|
CP0547993
|
N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-3-[[4-(2-hydroxyphenyl)pyrimidin-2-yl]amino]-4-methylbenzamide
Show/Hide
|
C37H37N5O4
|
1
|
| 1 |
IC50 = 1980 nM
|
|
|
|
CP0444569
|
N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-4-methyl-3-[(4-thiophen-2-ylpyrimidin-2-yl)amino]benzamide
Show/Hide
|
C35H35N5O3S
|
1
|
| 1 |
IC50 = 2310 nM
|
|
|
|
CP0532223
|
N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-4-methyl-3-[(4-phenylpyrimidin-2-yl)amino]benzamide
Show/Hide
|
C31H33N5O3
|
1
|
| 1 |
IC50 = 2470 nM
|
|
|
|
CP0532225
|
N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-5-hydroxy-4-oxochromene-2-carboxamide
Show/Hide
|
C29H28N2O6
|
1
|
| 1 |
IC50 = 2750 nM
|
|
|
|
CP0531430
|
N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-3-[[4-(4-fluorophenyl)pyrimidin-2-yl]amino]-4-methylbenzamide
Show/Hide
|
C31H32FN5O3
|
1
|
| 1 |
IC50 = 2950 nM
|
|
|
|
CP0531429
|
N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-3-[[4-(3-hydroxyphenyl)pyrimidin-2-yl]amino]-4-methylbenzamide
Show/Hide
|
C31H33N5O4
|
1
|
| 1 |
IC50 = 3010 nM
|
|
|
|
CP0552099
|
3-(4-chlorophenyl)-N-[(4-cyanophenyl)methyl]-4-oxophthalazine-1-carboxamide
Show/Hide
|
C23H15ClN4O2
|
1
|
| 1 |
IC50 = 3120 nM
|
|
|
|
CP0541483
|
4-tert-butyl-N-[2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]phenyl]benzamide
Show/Hide
|
C33H39N5O4
|
1
|
| 1 |
IC50 = 3420 nM
|
|
|
|
CP0532227
|
N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-3-[[4-(4-fluorophenyl)pyrimidin-2-yl]amino]-4-methylbenzamide
Show/Hide
|
C37H36FN5O3
|
1
|
| 1 |
IC50 = 4020 nM
|
|
|
|
CP0541484
|
2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-[4-(trifluoromethoxy)phenyl]benzamide
Show/Hide
|
C30H30F3N5O5
|
1
|
| 1 |
IC50 = 4520 nM
|
|
|
|
CP0543748
|
N-benzhydryl-3-(4-chlorophenyl)-4-oxophthalazine-1-carboxamide
Show/Hide
|
C28H20ClN3O2
|
1
|
| 1 |
IC50 = 5180 nM
|
|
|
|
CP0478387
|
N-(4-butylphenyl)-2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]benzamide
Show/Hide
|
C33H39N5O4
|
1
|
| 1 |
IC50 = 6250 nM
|
|
|
|
CP0543747
|
3-(4-chlorophenyl)-4-oxo-N-[[3-(trifluoromethoxy)phenyl]methyl]phthalazine-1-carboxamide
Show/Hide
|
C23H15ClF3N3O3
|
1
|
| 1 |
IC50 = 6350 nM
|
|
|
|
CP0036382
|
CAS_52-53-9
Show/Hide
|
C27H38N2O4
|
5
|
| 1 |
IC50 = 6470 nM
|
|
|
| 2 |
IC50 = 10730 nM
|
|
|
| 3 |
IC50 = 17250 nM
|
|
|
| 4 |
IC50 = 17550 nM
|
|
|
| 5 |
IC50 = 31280 nM
|
|
|
|
CP0451089
|
N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-6-fluoro-4-oxochromene-2-carboxamide
Show/Hide
|
C29H27FN2O5
|
1
|
| 1 |
IC50 = 6620 nM
|
|
|
|
CP0532222
|
N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-4-methyl-3-[(4-pyridin-2-ylpyrimidin-2-yl)amino]benzamide
Show/Hide
|
C30H32N6O3
|
1
|
| 1 |
IC50 = 6900 nM
|
|
|
|
CP0465652
|
N-(4-chlorophenyl)-2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]benzamide
Show/Hide
|
C29H30ClN5O4
|
1
|
| 1 |
IC50 = 6930 nM
|
|
|
|
CP0576510
|
3-(4-chlorophenyl)-N-[4-[2-(3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-4-oxophthalazine-1-carboxamide
Show/Hide
|
C32H27ClN4O2
|
1
|
| 1 |
IC50 = 6930 nM
|
|
|
|
CP0410563
|
2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-(4-methylphenyl)benzamide
Show/Hide
|
C30H33N5O4
|
1
|
| 1 |
IC50 = 7650 nM
|
|
|
|
CP0410565
|
2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-(3,4-dimethoxyphenyl)benzamide
Show/Hide
|
C31H35N5O6
|
1
|
| 1 |
IC50 = 7820 nM
|
|
|
|
CP0465651
|
2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-(4-fluorophenyl)benzamide
Show/Hide
|
C29H30FN5O4
|
1
|
| 1 |
IC50 = 8290 nM
|
|
|
|
CP0478388
|
2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-(4-methoxyphenyl)benzamide
Show/Hide
|
C30H33N5O5
|
1
|
| 1 |
IC50 = 8380 nM
|
|
|
|
CP0451522
|
2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-(3-methoxyphenyl)benzamide
Show/Hide
|
C30H33N5O5
|
1
|
| 1 |
IC50 = 8730 nM
|
|
|
|
CP0576506
|
N-(1H-benzimidazol-2-yl)-3-(4-chlorophenyl)-4-oxophthalazine-1-carboxamide
Show/Hide
|
C22H14ClN5O2
|
1
|
| 1 |
IC50 = 9350 nM
|
|
|
|
CP0532224
|
N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-4-oxochromene-2-carboxamide
Show/Hide
|
C29H28N2O5
|
1
|
| 1 |
IC50 = 9610 nM
|
|
|
|
CP0576508
|
3-(4-chlorophenyl)-4-oxo-N-[(3,4,5-trimethoxyphenyl)methyl]phthalazine-1-carboxamide
Show/Hide
|
C25H22ClN3O5
|
1
|
| 1 |
IC50 = 10410 nM
|
|
|
|
CP0465650
|
2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-(3-methylphenyl)benzamide
Show/Hide
|
C30H33N5O4
|
1
|
| 1 |
IC50 = 12160 nM
|
|
|
|
CP0576505
|
3-(4-chlorophenyl)-N-[4-(4-methylpiperazin-1-yl)phenyl]-4-oxophthalazine-1-carboxamide
Show/Hide
|
C26H24ClN5O2
|
1
|
| 1 |
IC50 = 12280 nM
|
|
|
|
CP0543746
|
3-(4-chlorophenyl)-N-(2-morpholin-4-ylethyl)-4-oxophthalazine-1-carboxamide
Show/Hide
|
C21H21ClN4O3
|
1
|
| 1 |
IC50 = 13620 nM
|
|
|
|
CP0571178
|
3-(4-chlorophenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-4-oxophthalazine-1-carboxamide
Show/Hide
|
C25H22ClN3O4
|
1
|
| 1 |
IC50 = 13790 nM
|
|
|
|
CP0576759
|
3-(4-chlorophenyl)-N-(4-morpholin-4-ylphenyl)-4-oxophthalazine-1-carboxamide
Show/Hide
|
C25H21ClN4O3
|
1
|
| 1 |
IC50 = 14460 nM
|
|
|
|
CP0036082
|
N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine
Show/Hide
|
C22H24ClFN4O3
|
1
|
| 1 |
IC50 = 19970 nM
|
|
|
|
CP0578337
|
N,N-dibenzyl-3-(4-chlorophenyl)-4-oxophthalazine-1-carboxamide
Show/Hide
|
C29H22ClN3O2
|
1
|
| 1 |
IC50 = 20610 nM
|
|
|
|
CP0390060
|
2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-(4-nitrophenyl)benzamide
Show/Hide
|
C29H30N6O6
|
1
|
| 1 |
IC50 = 21070 nM
|
|
|
|
CP0410562
|
2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-(2-methylphenyl)benzamide
Show/Hide
|
C30H33N5O4
|
1
|
| 1 |
IC50 = 21910 nM
|
|
|
|
CP0572938
|
3-(4-chlorophenyl)-4-oxo-N-(2-phenylethyl)phthalazine-1-carboxamide
Show/Hide
|
C23H18ClN3O2
|
1
|
| 1 |
IC50 = 22730 nM
|
|
|
|
CP0495662
|
N-(3-chlorophenyl)-2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]benzamide
Show/Hide
|
C29H30ClN5O4
|
1
|
| 1 |
IC50 = 22820 nM
|
|
|
|
CP0576760
|
3-(4-chlorophenyl)-N-[(4-methoxyphenyl)methyl]-4-oxophthalazine-1-carboxamide
Show/Hide
|
C23H18ClN3O3
|
1
|
| 1 |
IC50 = 24280 nM
|
|
|
|
CP0410564
|
2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-phenylbenzamide
Show/Hide
|
C29H31N5O4
|
1
|
| 1 |
IC50 = 25520 nM
|
|
|
|
CP0523551
|
2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-(2-nitrophenyl)benzamide
Show/Hide
|
C29H30N6O6
|
1
|
| 1 |
IC50 = 26920 nM
|
|
|
|
CP0410560
|
2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-(3-nitrophenyl)benzamide
Show/Hide
|
C29H30N6O6
|
1
|
| 1 |
IC50 = 27690 nM
|
|
|
|
CP0475330
|
2-[[1-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]triazol-4-yl]methoxy]-N-(3,4,5-trimethoxyphenyl)benzamide
Show/Hide
|
C32H37N5O7
|
1
|
| 1 |
IC50 = 31920 nM
|
|
|
|
CP0576509
|
3-(4-chlorophenyl)-4-oxo-N-(pyridin-4-ylmethyl)phthalazine-1-carboxamide
Show/Hide
|
C21H15ClN4O2
|
1
|
| 1 |
IC50 = 34750 nM
|
|
|
|
CP0569303
|
3-(4-chlorophenyl)-4-oxo-N-[(4-phenylphenyl)methyl]phthalazine-1-carboxamide
Show/Hide
|
C28H20ClN3O2
|
1
|
| 1 |
IC50 = 35120 nM
|
|
|
|
CP0568028
|
3-(4-chlorophenyl)-N-[2-(3-fluorophenyl)ethyl]-4-oxophthalazine-1-carboxamide
Show/Hide
|
C23H17ClFN3O2
|
1
|
| 1 |
IC50 = 46320 nM
|
|
|
|
CP0576507
|
3-(4-chlorophenyl)-N-[2-(3-chlorophenyl)ethyl]-4-oxophthalazine-1-carboxamide
Show/Hide
|
C23H17Cl2N3O2
|
1
|
| 1 |
IC50 = 46540 nM
|
|
|
|
CP0574618
|
3-(4-chlorophenyl)-4-oxo-N-(pyridin-3-ylmethyl)phthalazine-1-carboxamide
Show/Hide
|
C21H15ClN4O2
|
1
|
| 1 |
IC50 = 50900 nM
|
|
|
|
CP0543855
|
3-(4-chlorophenyl)-N-(3-morpholin-4-ylpropyl)-4-oxophthalazine-1-carboxamide
Show/Hide
|
C22H23ClN4O3
|
1
|
| 1 |
IC50 = 65560 nM
|
|
|
|
CP0444570
|
N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-7-methyl-4-oxochromene-2-carboxamide
Show/Hide
|
C30H30N2O5
|
1
|
| 1 |
IC50 = 84850 nM
|
|
|
|
CP0141589
|
3-((3S,6S)-6-Isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydro-pyrazino[1',2':1,6]pyrido[3,4-b]indol-3-yl)-propionic acid tert-butyl ester
Show/Hide
|
C26H35N3O5
|
1
|
| 1 |
IC50 = 86790 nM
|
|
|
|
CP0664710
|
SID49681823
Show/Hide
|
C27H30ClNO11
|
1
|
| 1 |
IC50 = 96910 nM
|
|
|
