| Compound ID |
Compound Name |
Compound Formula |
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CP0091326
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(3S,6S,9R,12S,15S,23S)-15-((S)-2-acetylamino-hexanoylamino)-9-benzyl-6-(3-guanidino-propyl)-12-(3H-imidazol-4-ylmethyl)-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18hexaaza-cyclotricosane-23-carboxylic acid amide
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C50H69N15O9
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16
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| 1 |
EC50 = 0.2042 nM
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| 2 |
EC50 = 1.5 nM
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| 3 |
EC50 = 1.8 nM
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| 4 |
EC50 = 1.85 nM
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| 5 |
EC50 = 1.9 nM
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| 6 |
EC50 = 2.4 nM
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| 7 |
EC50 = 3.1 nM
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| 8 |
EC50 = 5.1 nM
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| 9 |
EC50 = 33.9 nM
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| 10 |
IC50 = 1.2 nM
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| 11 |
IC50 = 1.25 nM
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| 12 |
IC50 = 1.3 nM
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| 13 |
IC50 = 1.9 nM
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| 14 |
IC50 = 2 nM
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| 15 |
IC50 = 9.8 nM
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| 16 |
Ki = 16.98 nM
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CP0041451
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CAS_75921-69-6
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C78H111N21O19
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5
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| 1 |
EC50 = 0.3 nM
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| 2 |
EC50 = 0.36 nM
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| 3 |
EC50 = 0.8 nM
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| 4 |
EC50 = 6.8 nM
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| 5 |
IC50 = 3.3 nM
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CP0376199
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(3S)-3-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-4-methylsulfanylbutanoyl]amino]acetyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-5-carbamimidamido-1-[[(2S)-1-(carboxymethylamino)-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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C74H99N21O16S
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2
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| 1 |
EC50 = 0.33 nM
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| 2 |
IC50 = 6.7 nM
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CP0473015
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(2S)-2-acetamido-N-[(2R)-1-[[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-amino-1-oxo-3-sulfanylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]-5-(diaminomethylideneamino)pentanamide
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C49H70N18O9S2
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2
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| 1 |
EC50 = 0.6918 nM
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| 2 |
Ki = 15.49 nM
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CP0390481
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(4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-hydroxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]hexanoyl]amino]-5-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-6-amino-1-[(2S)-2-[[(2S)-1-amino-3-methyl-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-2-oxoethyl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]pentanoic acid
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C78H113N21O18
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2
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| 1 |
EC50 = 0.8 nM
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| 2 |
IC50 = 3.3 nM
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CP0482142
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(10S,13S,16S,19R,22S)-19-benzyl-16-[3-(diaminomethylideneamino)propyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-7,12,15,18,21,24-hexaoxo-6,11,14,17,20,23-hexazaspiro[4.19]tetracosane-10-carboxamide
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C43H55N13O7
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2
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| 1 |
EC50 = 1 nM
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| 2 |
IC50 = 59 nM
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CP0403237
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(2S,5R,8R,11S,14S,17S)-8-benzyl-2-butyl-5,11-bis[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
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C43H62N14O7
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2
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| 1 |
EC50 = 1.2 nM
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| 2 |
IC50 = 140 nM
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CP0458133
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(S)-2-Acetamido-N-((R)-1-((2S,4S)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)-3-(1H-imidazol-4-yl)propanamide
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C36H44N8O4
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2
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| 1 |
EC50 = 1.3 nM
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| 2 |
Ki = 117 nM
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CP0045108
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(4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(2S)-6-amino-1-[(2S)-2-{[(1S)-1-carbamoyl-2-methylpropyl]carbamoyl}pyrrolidin-1-yl]-1-oxohexan-2-yl]carbamoyl}methyl)carbamoyl]-2-(1H-indol-3-yl)ethyl]carbamoyl}-4-carbamimidamidobutyl]carbamoyl}-2-phenylethyl]carbamoyl}-2-(1H-imidazol-5-yl)ethyl]carbamoyl}-4-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-acetamido-3-hydroxypropanamido]-3-(4-hydroxyphenyl)propanamido]-3-hydroxypropanamido]-4-(methylsulfanyl)butanamido]butanoic acid
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C77H109N21O19S
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4
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| 1 |
EC50 = 1.4 nM
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|
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| 2 |
EC50 = 6.7 nM
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| 3 |
EC50 = 16.7 nM
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| 4 |
IC50 = 30 nM
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CP0381782
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-4,7,10-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C57H77N15O9
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2
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| 1 |
EC50 = 1.47 nM
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| 2 |
IC50 = 2220 nM
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CP0382502
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]acetyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-aminooxy-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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C75H102N22O16
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2
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| 1 |
EC50 = 1.6 nM
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| 2 |
IC50 = 45 nM
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CP0404108
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(9S,12S,15S,18R,21S)-18-benzyl-15-[3-(diaminomethylideneamino)propyl]-21-(1H-imidazol-5-ylmethyl)-12-(1H-indol-3-ylmethyl)-6,11,14,17,20,23-hexaoxo-5,10,13,16,19,22-hexazaspiro[3.19]tricosane-9-carboxamide
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C42H53N13O7
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2
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| 1 |
EC50 = 1.8 nM
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| 2 |
IC50 = 55 nM
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CP0462964
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(3S,6S,9R,12S,15S,23S)-15-[(2S)-2-aminohexanamido]-6-(3-carbamimidamidopropyl)-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexaazacyclotricosane-23-carboxamide
Show/Hide
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C52H69N15O8
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2
|
| 1 |
EC50 = 1.85 nM
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|
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| 2 |
IC50 = 1.25 nM
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CP0762853
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15-(2-Acetylamino-hexanoylamino)-9-benzyl-6-(3-guanidino-propyl)-12-(3H-imidazol-4-ylmethyl)-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18hexaaza-cyclotetracosane-24-carboxylic acid amide
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C51H71N15O9
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2
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| 1 |
EC50 = 1.88 nM
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| 2 |
Ki = 1.2 nM
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CP0377559
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(3S,9S,17S,20S,23S,26R,29S)-9-[[(2S)-2-acetamidohexanoyl]amino]-23-[3-(diaminomethylideneamino)propyl]-20-(1H-indol-3-ylmethyl)-26-(naphthalen-2-ylmethyl)-2,8,11,19,22,25,28-heptaoxo-1,7,12,18,21,24,27-heptazatricyclo[27.3.0.03,7]dotriacontane-17-carboxamide
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C58H78N14O10
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2
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| 1 |
EC50 = 1.9 nM
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| 2 |
IC50 = 2.4 nM
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CP0383561
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(9S,12S,15S,18R,21S)-15-[3-(diaminomethylideneamino)propyl]-21-(1H-imidazol-5-ylmethyl)-12-(1H-indol-3-ylmethyl)-18-(naphthalen-2-ylmethyl)-7,11,14,17,20,23-hexaoxo-6,10,13,16,19,22-hexazaspiro[4.18]tricosane-9-carboxamide
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C46H55N13O7
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2
|
| 1 |
EC50 = 1.9 nM
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| 2 |
IC50 = 16 nM
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CP0388054
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Ac-Tyr-Val-Nle-Gly-His-DPhe-Arg-Trp-Asp-Arg-Phe-Gly-NH2)
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C77H104N22O16
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2
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| 1 |
EC50 = 2 nM
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| 2 |
IC50 = 2 nM
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CP0393265
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Ac-Tyr-Val-Nle-Gly-His-D-Phe-Arg-Trp-Asp-Arg-Phe-Gly-NH2
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C77H104N22O17
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2
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| 1 |
EC50 = 2 nM
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| 2 |
IC50 = 2 nM
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CP0870111
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(3R,6S,9S,12R,15S)-12-benzyl-9-(3-carbamimidamidopropyl)-15-(1H-imidazol-5-ylmethyl)-6-(1H-indol-3-ylmethyl)-19-nitro-5,8,11,14,17-pentaoxo-2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17-hexadecahydro-1,4,7,10,13,16-benzothiapentazacyclononadecine-3-carboxamide
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|
C42H47N13O8S
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2
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| 1 |
EC50 = 2 nM
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| 2 |
IC50 = 40 nM
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CP0455645
|
BREMELANOTIDE
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C50H68N14O10
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2
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| 1 |
EC50 = 2.399 nM
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| 2 |
Ki = 190.55 nM
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CP0389079
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(8S,11S,14S,17R,20S)-14-[3-(diaminomethylideneamino)propyl]-20-(1H-imidazol-5-ylmethyl)-11-(1H-indol-3-ylmethyl)-17-(naphthalen-2-ylmethyl)-6,10,13,16,19,22-hexaoxo-5,9,12,15,18,21-hexazaspiro[3.18]docosane-8-carboxamide
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C45H53N13O7
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2
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| 1 |
EC50 = 3.2 nM
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| 2 |
IC50 = 5.1 nM
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CP0402650
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(11S,14S,17S,20R,23S)-20-benzyl-17-[3-(diaminomethylideneamino)propyl]-23-(1H-imidazol-5-ylmethyl)-14-(1H-indol-3-ylmethyl)-8,13,16,19,22,25-hexaoxo-7,12,15,18,21,24-hexazaspiro[5.19]pentacosane-11-carboxamide
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C44H57N13O7
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2
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| 1 |
EC50 = 4.1 nM
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| 2 |
IC50 = 74 nM
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CP0084312
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(S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)-2-(4-phenyl-butyrylamino)-propionylamino]-3-phenyl-propionylamino}-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
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|
C42H51N11O5
|
1
|
| 1 |
EC50 = 4.7 nM
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CP0390482
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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|
C74H102N20O15
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2
|
| 1 |
EC50 = 5 nM
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| 2 |
IC50 = 4.1 nM
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CP0383567
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(10S,13S,16S,19R,22S)-16-[3-(diaminomethylideneamino)propyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-19-(naphthalen-2-ylmethyl)-7,12,15,18,21,24-hexaoxo-6,11,14,17,20,23-hexazaspiro[4.19]tetracosane-10-carboxamide
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C47H57N13O7
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2
|
| 1 |
EC50 = 5 nM
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| 2 |
IC50 = 1.2 nM
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CP0047872
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(S)-2-{(S)-2-[(S)-2-[2-(4-Chloro-phenoxy)-acetylamino]-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
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|
C40H46ClN11O6
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1
|
| 1 |
EC50 = 6 nM
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CP0390103
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(4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-hydroxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-6-amino-1-[(2S)-2-[[(2S)-1-amino-3-methyl-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-2-oxoethyl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]pentanoic acid
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|
C77H111N21O18S
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2
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| 1 |
EC50 = 6.7 nM
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| 2 |
IC50 = 30 nM
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CP0045745
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(S)-2-{(R)-2-[(S)-2-Acetylamino-3-(1H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
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C34H43N11O5
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2
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| 1 |
EC50 = 7.1 nM
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| 2 |
IC50 = 63 nM
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CP0406932
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(2S)-2-[[2-[[(2S)-2-acetamidohexanoyl]amino]acetyl]amino]-6-amino-N-[(2R)-1-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]hexanamide
Show/Hide
|
C44H65N13O8
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2
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| 1 |
EC50 = 7.943 nM
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| 2 |
IC50 = 199.53 nM
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CP0182893
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(S)-2-{(S)-2-[(S)-2-[2-(4-Chloro-phenyl)-acetylamino]-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
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C40H46ClN11O5
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1
|
| 1 |
EC50 = 9.3 nM
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CP0551927
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(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-21,21-dimethyl-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.3.1]octacosa-1(28),24,26-triene-5-carboxamide
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C56H74N14O8S2
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2
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| 1 |
EC50 = 9.4 nM
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| 2 |
IC50 = 244 nM
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CP0376213
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-4,10-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
|
C56H75N15O9
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2
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| 1 |
EC50 = 9.92 nM
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| 2 |
IC50 = 412 nM
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CP0394004
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(S)-2-acetamido-N1-((R)-1-((2S,4S)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)pentanediamide
Show/Hide
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C32H41N7O4
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2
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| 1 |
EC50 = 10 nM
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| 2 |
Ki = 835 nM
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CP0393261
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(3S)-3-[[(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-aminooxy-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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|
C80H105N19O16
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2
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| 1 |
EC50 = 11 nM
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| 2 |
IC50 = 3 nM
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CP0376221
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,4,13-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
|
C57H77N15O9
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3
|
| 1 |
EC50 = 11 nM
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| 2 |
IC50 = 106 nM
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| 3 |
Kd = 10 nM
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CP0421219
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(3S)-N-((1R)-1-[(4-Fluorophenyl)methyl]-2-{(2S)-4-[(1S)-2-(methylamino)-1-(2-naphthalenylmethyl)-2-oxoethyl]-3-oxo-2-propyl-1-piperazinyl}-2-oxoethyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide
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C40H44FN5O4
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2
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| 1 |
EC50 = 12 nM
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| 2 |
Ki = 80 nM
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CP0402649
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(5S,8R,11S,14S,17S)-8-benzyl-11-[3-(diaminomethylideneamino)propyl]-5-(1H-imidazol-5-ylmethyl)-14-(1H-indol-3-ylmethyl)-2,2-dimethyl-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
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C41H53N13O7
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2
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| 1 |
EC50 = 12 nM
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| 2 |
IC50 = 57 nM
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CP0184629
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(O)C-(C6H4)-C(O)-c[His-D-Phe-Arg-Trp-Lys]-NH2) (MK-6)
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C46H55N13O7
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2
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| 1 |
EC50 = 13 nM
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| 2 |
Ki = 280 nM
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CP0217814
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(S)-2-{(S)-2-[(S)-2-(2,2-Dimethyl-propionylamino)-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
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C37H49N11O5
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1
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| 1 |
EC50 = 13 nM
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CP0863666
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H-Tyr-Val-Nle-Gly-Pro-Phe-Arg-D-Nal(2'')-Asp-Arg-Phe-Gly-NH2
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C76H102N18O16
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2
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| 1 |
EC50 = 13 nM
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| 2 |
IC50 = 32 nM
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CP0376248
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-7,10-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
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C56H75N15O9
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2
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| 1 |
EC50 = 13.2 nM
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| 2 |
IC50 = 65 nM
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CP0375705
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Ac-Nle-c[Asp-trans-4-guanidinyl-Pro-DPhe-Arg-Trp-Lys]-NH2
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C50H72N16O9
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2
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| 1 |
EC50 = 14 nM
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| 2 |
IC50 = 1 nM
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CP0376447
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(S)-2-acetamido-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)-3-(1H-imidazol-4-yl)propanamide
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C36H44N8O4
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2
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| 1 |
EC50 = 15 nM
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| 2 |
Ki = 26 nM
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CP0400476
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-4,13-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
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C56H75N15O9
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2
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| 1 |
EC50 = 16 nM
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| 2 |
IC50 = 3660 nM
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CP0040024
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(S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)-2-(3-phenyl-propionylamino)-propionylamino]-3-phenyl-propionylamino}-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
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C41H49N11O5
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1
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| 1 |
EC50 = 17 nM
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CP0094502
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(O)C-(C6H4)-C(O)-c[His-D-Nal(2')-Arg-Trp-Lys]-NH2) (MK-7)
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C50H57N13O7
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2
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| 1 |
EC50 = 18 nM
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| 2 |
Ki = 7.8 nM
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CP0383563
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(5S,8R,11S,14S,17S)-11-[3-(diaminomethylideneamino)propyl]-5-(1H-imidazol-5-ylmethyl)-14-(1H-indol-3-ylmethyl)-2,2-dimethyl-8-(naphthalen-2-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
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C45H55N13O7
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2
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| 1 |
EC50 = 19 nM
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| 2 |
IC50 = 27 nM
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CP0507015
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(2S)-2-[[(3S,6S,9R,12S,15S,18S)-3-[[(2S)-2-aminopropanoyl]amino]-9-benzyl-12-[3-(diaminomethylideneamino)propyl]-6-(1H-imidazol-5-ylmethyl)-15-(1H-indol-3-ylmethyl)-4,7,10,13,16-pentaoxo-1,5,8,11,14,17,21,22-octazabicyclo[18.2.1]tricosa-20(23),21-diene-18-carbonyl]amino]-4-methylsulfanylbutanoic acid
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C48H63N17O9S
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1
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| 1 |
EC50 = 19.4 nM
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CP0432640
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1-[3-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,37S,40S,43R,46S)-43-benzyl-4,19-bis[(2S)-butan-2-yl]-34-(3-carbamimidamidopropyl)-28-[(1S)-1-hydroxyethyl]-22-(hydroxymethyl)-46-(1H-imidazol-5-ylmethyl)-37-(1H-indol-3-ylmethyl)-25,38-dimethyl-3,6,12,18,21,24,27,30,33,36,39,42,45,48-tetradecaoxo-50,51-dithia-2,5,11,17,20,23,26,29,32,35,38,41,44,47-tetradecazatetracyclo[29.17.4.07,11.013,17]dopentacontan-40-yl]propyl]guanidine
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C77H113N23O16S2
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2
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| 1 |
EC50 = 20.42 nM
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| 2 |
Ki = 323.59 nM
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CP0442686
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N-[(2R)-3-(4-fluorophenyl)-1-[(2S)-4-[(2S)-1-(methylamino)-3-naphthalen-2-yl-1-oxopropan-2-yl]-3-oxo-2-propylpiperazin-1-yl]-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
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C35H40FN5O5
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2
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| 1 |
EC50 = 25 nM
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| 2 |
Ki = 128 nM
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CP0440073
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(2S)-2-[[2-[[2-[acetyl(butyl)amino]acetyl]amino]acetyl]amino]-6-amino-N-[(2R)-1-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]hexanamide
Show/Hide
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C44H65N13O8
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2
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| 1 |
EC50 = 25.12 nM
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| 2 |
IC50 = 125.89 nM
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CP0432502
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(2S,5S,8R,11S,14S,17S)-8-benzyl-2-butyl-11-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-3,6,9,12,15,20-hexaoxo-5-propan-2-yl-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
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C42H59N11O7
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2
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| 1 |
EC50 = 27 nM
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| 2 |
IC50 = 600 nM
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CP0378391
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(4R,7S,10S,13S)-4-benzyl-7-[3-(diaminomethylideneamino)propyl]-10-(1H-indol-3-ylmethyl)-2,5,8,11,19-pentaoxo-3,6,9,12,18,21,24-heptazabicyclo[18.4.0]tetracosa-1(24),20,22-triene-13-carboxamide
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C38H46N12O6
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2
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| 1 |
EC50 = 27 nM
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| 2 |
IC50 = 1100 nM
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CP0228189
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(S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)-2-phenylacetylamino-propionylamino]-3-phenyl-propionylamino}-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
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C40H47N11O5
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1
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| 1 |
EC50 = 28 nM
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CP0384353
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(11S,14S,17S,20R,23S)-20-benzyl-17-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-2,13,16,19,22-pentaoxo-1,6,12,15,18,21-hexazabicyclo[21.3.0]hexacosane-11-carboxamide
Show/Hide
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C41H57N11O6
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2
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| 1 |
EC50 = 29 nM
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| 2 |
IC50 = 385 nM
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CP0408790
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(9S,12S,15S,18R,21S)-18-benzyl-15-[3-(diaminomethylideneamino)propyl]-21-(1H-imidazol-5-ylmethyl)-12-(1H-indol-3-ylmethyl)-7,11,14,17,20,23-hexaoxo-6,10,13,16,19,22-hexazaspiro[4.18]tricosane-9-carboxamide
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C42H53N13O7
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2
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| 1 |
EC50 = 30 nM
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| 2 |
IC50 = 10 nM
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CP0437025
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(4R,7S,10S,13R,16S,19S,22R)-22-[[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]amino]-13-benzyl-16-(1H-imidazol-5-ylmethyl)-7-(1H-indol-3-ylmethyl)-10,19-dimethyl-6,9,12,15,18,21-hexaoxo-1,2-dithia-5,8,11,14,17,20-hexazacyclotricosane-4-carboxamide
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C46H61N15O9S2
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1
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| 1 |
EC50 = 30.9 nM
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CP0404106
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(10S,13S,16S,19R,22S)-19-benzyl-16-[3-(diaminomethylideneamino)propyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-8,12,15,18,21,24-hexaoxo-7,11,14,17,20,23-hexazaspiro[5.18]tetracosane-10-carboxamide
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C43H55N13O7
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2
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| 1 |
EC50 = 33 nM
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| 2 |
IC50 = 11 nM
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CP0432499
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(2S,5S,8R,11S,14S,17S)-8-benzyl-2-butyl-11-[3-(diaminomethylideneamino)propyl]-5-(1H-imidazol-5-ylmethyl)-14-(1H-indol-3-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
Show/Hide
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C43H57N13O7
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2
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| 1 |
EC50 = 37 nM
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| 2 |
IC50 = 560 nM
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CP0440776
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(2S)-N-((1R)-1-[(4-Fluorophenyl)methyl]-2-{(2S)-4-[(1S)-2-(methylamino)-1-(2-naphthalenylmethyl)-2-oxoethyl]-3-oxo-2-propyl-1-piperazinyl}-2-oxoethyl)-2-pyrrolidinecarboxamide
Show/Hide
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C35H42FN5O4
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2
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| 1 |
EC50 = 40 nM
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| 2 |
Ki = 165 nM
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CP0133486
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(D)-(S)-5-Guanidino-2-{(S)-2-[(S)-2-(2-hydroxy-3-phenyl-propionylamino)-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
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C41H49N11O6
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1
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| 1 |
EC50 = 40.5 nM
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CP0374873
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(S)-2-acetamido-N1-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)pentanediamide
Show/Hide
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C35H45N7O5
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2
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| 1 |
EC50 = 42 nM
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| 2 |
Ki = 50 nM
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CP0377558
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(3R,6R,14R,17S,20S,23S,26R)-6-[[(2S)-2-acetamidohexanoyl]amino]-20-[3-(diaminomethylideneamino)propyl]-3,17-bis(1H-indol-3-ylmethyl)-23-(naphthalen-2-ylmethyl)-2,5,8,16,19,22,25-heptaoxo-1,4,9,15,18,21,24-heptazabicyclo[24.3.0]nonacosane-14-carboxamide
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C64H81N15O10
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2
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| 1 |
EC50 = 42 nM
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| 2 |
IC50 = 11.1 nM
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CP0421220
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(S)-2-((S)-4-((R)-2-Acetamido-3-amino propan-(4-fluorophenyl)-propanoyl)-2-oxo-3-propylpiperazin-1-yl)-N-methyl-3-(naphthalen-2-yl)propanamide
Show/Hide
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C34H42FN5O4
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2
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| 1 |
EC50 = 44 nM
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| 2 |
Ki = 322 nM
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CP0440775
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(2S)-N-((1R)-1-[(4-Fluorophenyl)methyl]-2-{(2S)-4-[(1S)-2-(methylamino)-1-(2-naphthalenylmethyl)-2-oxoethyl]-3-oxo-2-propyl-1-piperazinyl}-2-oxoethyl)-2-piperidinecarboxamide
Show/Hide
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C36H44FN5O4
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2
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| 1 |
EC50 = 44 nM
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| 2 |
Ki = 155 nM
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CP0228609
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(S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)-2-pentanoylamino-propionylamino]-3-phenyl-propionylamino}-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
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C37H49N11O5
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1
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| 1 |
EC50 = 45 nM
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CP0858763
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(3R,6S,9S,12S,15S)-9-(3-carbamimidamidopropyl)-15-(1H-imidazol-5-ylmethyl)-6-(1H-indol-3-ylmethyl)-12-(naphthalen-2-ylmethyl)-19-nitro-5,8,11,14,17-pentaoxo-2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17-hexadecahydro-1,4,7,10,13,16-benzothiapentazacyclononadecine-3-carboxamide
Show/Hide
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C46H49N13O8S
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2
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| 1 |
EC50 = 50 nM
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| 2 |
IC50 > 1000 nM
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CP0388186
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(2S)-N-Methyl-2-[(3S)-4-(N-methyl-L-alanyl-4-fluoro-D-phenylalanyl)-2-oxo-3-propyl-1-piperazinyl]-3-(2-naphthalenyl)propanamide
Show/Hide
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C34H42FN5O4
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2
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| 1 |
EC50 = 51 nM
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| 2 |
Ki = 207 nM
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CP0421224
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(S)-2-((S)-4-((R)-3-(4-Fluorophenyl)-2-(2-(methylamino)acetamido)propanoyl)-2-oxo-3-propylpiperazin-1-yl)-N-methyl-3-(naphthalen-2-yl)propanamide
Show/Hide
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C33H40FN5O4
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2
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| 1 |
EC50 = 52 nM
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| 2 |
Ki = 282 nM
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CP0859091
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(S)-2-((R)-2-((S)-4-acetamido-3-oxo-4,5-dihydroazepino[3,4-b]indol-2(1H,3H,10H)-yl)-3-phenylpropanamido)-N-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-5-guanidinopentanamide
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C40H46N10O5
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1
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| 1 |
EC50 = 52 nM
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CP0848658
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(S)-2-((R)-2-((S)-7-acetamido-6-oxo-7,8-dihydro-4H-[1,2,3]triazolo[1,5-a][1,4]diazepin-5(6H)-yl)-3-phenylpropanamido)-N-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-5-guanidinopentanamide
Show/Hide
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C34H42N12O5
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2
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| 1 |
EC50 = 55 nM
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| 2 |
IC50 = 1000 nM
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CP0858758
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(3R,6S,9S,12R,15S)-12-benzyl-9-(3-carbamimidamidopropyl)-15-(1H-imidazol-5-ylmethyl)-6-(naphthalen-2-ylmethyl)-19-nitro-5,8,11,14,17-pentaoxo-2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17-hexadecahydro-1,4,7,10,13,16-benzothiapentazacyclononadecine-3-carboxamide
Show/Hide
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C44H48N12O8S
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2
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| 1 |
EC50 = 56 nM
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| 2 |
IC50 = 610 nM
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CP0389091
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(2S)-2-[[(2R)-2-[[(2S)-2-acetamido-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(4-bromophenyl)propanoyl]amino]-N-[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]hexanamide
Show/Hide
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C34H41BrN8O5
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2
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| 1 |
EC50 = 57 nM
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| 2 |
IC50 = 224 nM
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CP0257564
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N'-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]oxamide
Show/Hide
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C34H42N12O6
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1
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| 1 |
EC50 = 58 nM
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CP0388184
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1-Amino-N-((R)-3-(4-fluorophenyl)-1-((S)-4-((S)-1-(methylamino)-3-(naphthalen-2-yl)-1-oxopropan-2-yl)-2-propylpiperazin-1-yl)-1-oxopropan-2-yl)cyclopentanecarboxamide
Show/Hide
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C36H44FN5O4
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2
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| 1 |
EC50 = 58 nM
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| 2 |
Ki = 471 nM
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CP0341428
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4-[[(2S)-1-[[(2R)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
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C42H57N13O8
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2
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| 1 |
EC50 = 68 nM
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| 2 |
Ki = 140 nM
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CP0442493
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(S)-2-acetamido-N-((R)-1-((2S,4S)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)-3-(4-hydroxyphenyl)propanamide
Show/Hide
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C39H46N6O5
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2
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| 1 |
EC50 = 68 nM
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| 2 |
Ki = 425 nM
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CP0197083
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9-Benzyl-6-(3-guanidino-propyl)-12-(3H-imidazol-4-ylmethyl)-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18hexaaza-cyclotricosane-23-carboxylic acid amide
Show/Hide
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C42H55N13O7
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2
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| 1 |
EC50 = 70 nM
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| 2 |
Ki = 77 nM
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CP0228070
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6-(3-Guanidino-propyl)-12-(3H-imidazol-4-ylmethyl)-3-(1H-indol-3-ylmethyl)-9-naphthalen-2-ylmethyl-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18hexaaza-cyclotricosane-23-carboxylic acid amide
Show/Hide
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C46H57N13O7
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2
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| 1 |
EC50 = 70 nM
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| 2 |
Ki = 12.1 nM
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CP0182921
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N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]cyclopropanecarboxamide
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C36H45N11O5
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1
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| 1 |
EC50 = 71 nM
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CP0383562
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(5S,8R,11S,14S,17S)-11-[3-(diaminomethylideneamino)propyl]-5-(1H-imidazol-5-ylmethyl)-14-(1H-indol-3-ylmethyl)-2,2-dimethyl-8-(naphthalen-2-ylmethyl)-3,6,9,12,15,19-hexaoxo-1,4,7,10,13,16-hexazacyclononadecane-17-carboxamide
Show/Hide
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C44H53N13O7
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2
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| 1 |
EC50 = 73 nM
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| 2 |
IC50 = 14 nM
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CP0184588
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5-Benzyl-8-(3-guanidino-propyl)-2-(3H-imidazol-4-ylmethyl)-11-(1H-indol-3-ylmethyl)-3,6,9,12,20,24-hexaoxo-1,4,7,10,13,19hexaaza-cyclotetracosane-14-carboxylic acid amide
Show/Hide
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C43H57N13O7
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2
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| 1 |
EC50 = 75 nM
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| 2 |
Ki = 110 nM
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CP0402648
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(10S,13S,16S,19R,22S)-16-[3-(diaminomethylideneamino)propyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-19-(naphthalen-2-ylmethyl)-8,12,15,18,21,24-hexaoxo-7,11,14,17,20,23-hexazaspiro[5.18]tetracosane-10-carboxamide
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C47H57N13O7
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2
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| 1 |
EC50 = 76 nM
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| 2 |
IC50 = 3.9 nM
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CP0404107
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(5S,8R,11S,14S,17S)-8-benzyl-11-[3-(diaminomethylideneamino)propyl]-5-(1H-imidazol-5-ylmethyl)-14-(1H-indol-3-ylmethyl)-2,2-dimethyl-3,6,9,12,15,19-hexaoxo-1,4,7,10,13,16-hexazacyclononadecane-17-carboxamide
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C40H51N13O7
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2
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| 1 |
EC50 = 76 nM
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| 2 |
IC50 = 20 nM
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CP0371977
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1-Amino-N-((R)-3-(4-fluorophenyl)-1-((S)-4-((S)-1-(methylamino)-3-(naphthalen-2-yl)-1-oxopropan-2-yl)-2-propylpiperazin-1-yl)-1-oxopropan-2-yl)cyclobutanecarboxamide
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C35H42FN5O4
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2
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| 1 |
EC50 = 84 nM
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| 2 |
Ki = 377 nM
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CP0376444
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(S)-2-acetamido-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)-3-(4-hydroxyphenyl)propanamide
Show/Hide
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C39H46N6O5
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2
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| 1 |
EC50 = 85 nM
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| 2 |
Ki = 42 nM
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CP0049389
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(S)-2-{(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
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C36H47N11O5
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1
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| 1 |
EC50 = 93.3 nM
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CP0427899
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(7S,10R,13S,16S,19S)-10-benzyl-13-[3-(diaminomethylideneamino)propyl]-16-(1H-indol-3-ylmethyl)-2,8,11,14,17,25-hexaoxo-3,9,12,15,18,24-hexazatricyclo[24.4.0.03,7]triaconta-1(30),26,28-triene-19-carboxamide
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C45H55N11O7
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2
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| 1 |
EC50 = 95 nM
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| 2 |
IC50 > 1000 nM
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CP0101637
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N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]benzamide
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C39H45N11O5
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1
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| 1 |
EC50 = 98.3 nM
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CP0847693
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(3R,6S,9S,12S,25aS)-3-benzyl-6-(3-carbamimidamidopropyl)-9-(1H-indol-3-ylmethyl)-1,4,7,10,18,21-hexaoxo-1H,2H,3H,4H,5H,6H,7H,8H,9H,10H,11H,12H,13H,14H,15H,16H,17H,18H,21H,23H,24H,25H,25aH-pyrrolo[2,1-l]1,4,7,10,13,18-hexaazacyclotricosane-12-carboxamide
Show/Hide
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C41H53N11O7
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2
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| 1 |
EC50 = 100 nM
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| 2 |
IC50 > 1000 nM
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CP0377259
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N-[(2R)-3-(4-fluorophenyl)-1-[(2S)-4-[(2S)-1-(methylamino)-3-naphthalen-2-yl-1-oxopropan-2-yl]-3-oxo-2-propylpiperazin-1-yl]-1-oxopropan-2-yl]pyridine-4-carboxamide
Show/Hide
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C36H38FN5O4
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2
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| 1 |
EC50 = 103 nM
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| 2 |
Ki = 309 nM
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CP0421223
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N-[(2R)-3-(4-fluorophenyl)-1-[(2S)-4-[(2S)-1-(methylamino)-3-naphthalen-2-yl-1-oxopropan-2-yl]-3-oxo-2-propylpiperazin-1-yl]-1-oxopropan-2-yl]piperidine-4-carboxamide
Show/Hide
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C36H44FN5O4
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2
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| 1 |
EC50 = 108 nM
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| 2 |
Ki = 127 nM
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CP0421222
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2-{4-[2-Acetylamino-3-(4-fluoro-phenyl)-propionyl]-2-oxo-3-propyl-piperazin-1-yl}-N-methyl-3-naphthalen-2-yl-propionamide
Show/Hide
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C32H37FN4O4
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2
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| 1 |
EC50 = 113 nM
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| 2 |
Ki = 201 nM
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CP0389097
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(2S)-2-[[(2R)-2-[[(2S)-2-acetamido-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-N-[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]hexanamide
Show/Hide
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C34H41ClN8O5
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2
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| 1 |
EC50 = 116 nM
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| 2 |
IC50 > 1000 nM
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CP0204764
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(S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)-2-(3,3,3-trifluoro-propionylamino)-propionylamino]-3-phenyl-propionylamino}-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
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C35H42F3N11O5
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1
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| 1 |
EC50 = 120 nM
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CP0389089
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(2S)-2-[[(2R)-2-[[(2S)-2-acetamido-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-N-[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]hexanamide
Show/Hide
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C34H42N8O5
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2
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| 1 |
EC50 = 120 nM
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| 2 |
IC50 > 1000 nM
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CP0390462
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(2S)-2-[[(3S,6S,9R,12S,15S,18S)-9-benzyl-3-[[(2S)-2,6-diaminohexanoyl]amino]-12-[3-(diaminomethylideneamino)propyl]-6-(1H-imidazol-5-ylmethyl)-15-(1H-indol-3-ylmethyl)-4,7,10,13,16-pentaoxo-1,5,8,11,14,17,21,22-octazabicyclo[18.2.1]tricosa-20(23),21-diene-18-carbonyl]amino]-4-methylsulfanylbutanoic acid
Show/Hide
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C51H70N18O9S
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1
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| 1 |
EC50 = 122.6 nM
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CP0336462
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(S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)-2-isobutyrylamino-propionylamino]-3-phenyl-propionylamino}-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
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C36H47N11O5
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1
|
| 1 |
EC50 = 130 nM
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CP0372168
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Ac-Nle-c[Asp-trans-4-guanidinyl-Pro-DNal(2')-Arg-Trp-Lys]-NH2
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C54H74N16O9
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2
|
| 1 |
EC50 = 130 nM
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|
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| 2 |
IC50 = 2.3 nM
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CP0376683
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(3S)-3-[[(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]acetyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-aminooxy-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
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C75H102N22O16
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2
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| 1 |
EC50 = 140 nM
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| 2 |
IC50 = 25 nM
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CP0421221
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N-[(2R)-3-(4-fluorophenyl)-1-[(2S)-4-[(2S)-1-(methylamino)-3-naphthalen-2-yl-1-oxopropan-2-yl]-3-oxo-2-propylpiperazin-1-yl]-1-oxopropan-2-yl]pyridine-3-carboxamide
Show/Hide
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C36H38FN5O4
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2
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| 1 |
EC50 = 147 nM
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| 2 |
Ki = 144 nM
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CP0430803
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(S)-2-((S)-3-allyl-4-((R)-2-amino-3-(4-fluorophenyl)propanoyl)-2-oxopiperazin-1-yl)-N-methyl-3-(naphthalen-2-yl)propanamide
Show/Hide
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C30H33FN4O3
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1
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| 1 |
EC50 = 148 nM
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CP0423112
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(S)-2-((S)-4-((R)-2-Amino-3-(4-fluorophenyl)propanoyl)-2-oxo-3-propylpiperazin-1-yl)-N-methyl-3-(naphthalen-2-yl)propanamide
Show/Hide
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C30H35FN4O3
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2
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| 1 |
EC50 = 149 nM
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| 2 |
Ki = 727 nM
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CP0873314
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(3R,6S,9S,12S,15S)-12-[(4-aminophenyl)methyl]-9-(3-carbamimidamidopropyl)-15-(1H-imidazol-5-ylmethyl)-6-(1H-indol-3-ylmethyl)-19-nitro-5,8,11,14,17-pentaoxo-2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17-hexadecahydro-1,4,7,10,13,16-benzothiapentazacyclononadecine-3-carboxamide
Show/Hide
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C42H48N14O8S
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2
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| 1 |
EC50 = 150 nM
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| 2 |
IC50 > 1000 nM
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CP0393526
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(2S)-2-[[2-[[2-[acetyl(butyl)amino]acetyl]amino]acetyl]amino]-6-amino-N-[(2R)-1-[[2-[[2-[(2-amino-2-oxoethyl)amino]-2-oxoethyl]-[2-(1H-indol-3-yl)ethyl]amino]-2-oxoethyl]-[3-(diaminomethylideneamino)propyl]amino]-1-oxo-3-phenylpropan-2-yl]hexanamide
Show/Hide
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C45H67N13O8
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2
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| 1 |
EC50 = 158.49 nM
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| 2 |
IC50 = 3162.28 nM
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CP0403572
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(2S)-2-[[2-[[(2S)-2-acetamidohexanoyl]amino]acetyl]amino]-6-amino-N-[(2R)-1-[[2-[[2-[(2-amino-2-oxoethyl)amino]-2-oxoethyl]-[2-(1H-indol-3-yl)ethyl]amino]-2-oxoethyl]-[3-(diaminomethylideneamino)propyl]amino]-1-oxo-3-phenylpropan-2-yl]hexanamide
Show/Hide
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C45H67N13O8
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2
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| 1 |
EC50 = 158.49 nM
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| 2 |
IC50 = 1995.26 nM
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CP0100500
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(S)-2-{(S)-2-[(S)-2-(2-Cyano-acetylamino)-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
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C35H42N12O5
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1
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| 1 |
EC50 = 160 nM
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CP0149367
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(R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid [(R)-1-(4-chloro-benzyl)-2-(4-cyclohexyl-4-[1,2,4]triazol-1-ylmethyl-piperidin-1-yl)-2-oxo-ethyl]-amide
Show/Hide
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C33H41ClN6O2
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4
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| 1 |
EC50 = 160 nM
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| 2 |
EC50 = 1400 nM
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| 3 |
Ki = 125 nM
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| 4 |
Ki = 2300 nM
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CP0437028
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(2S)-2-[[(2S,5S,8R,11S,14S,17S)-8-benzyl-2,11-bis[3-(diaminomethylideneamino)propyl]-5-(1H-imidazol-5-ylmethyl)-14-(1H-indol-3-ylmethyl)-3,6,9,12,15-pentaoxo-1,4,7,10,13,16,20,21-octazabicyclo[17.2.1]docosa-19(22),20-diene-17-carbonyl]amino]-4-methylsulfanylbutanoic acid
Show/Hide
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C48H64N18O8S
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1
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| 1 |
EC50 = 160 nM
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CP0436848
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(2S)-2-[[(3S,6S,9R,12S,15S,18S)-9-benzyl-3-[[(2S)-2,6-diaminohexanoyl]amino]-12-[3-(diaminomethylideneamino)propyl]-6-(1H-imidazol-5-ylmethyl)-15-(1H-indol-3-ylmethyl)-4,7,10,13,16-pentaoxo-1,5,8,11,14,17,21,22-octazabicyclo[18.2.1]tricosa-20(23),21-diene-18-carbonyl]amino]propanoic acid
Show/Hide
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C49H66N18O9
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1
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| 1 |
EC50 = 161.7 nM
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CP0376217
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,4-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C56H75N15O9
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2
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| 1 |
EC50 = 162 nM
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| 2 |
IC50 = 17.8 nM
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CP0308897
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(S)-2-{(S)-2-[(S)-2-acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
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C34H43N11O5
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3
|
| 1 |
EC50 = 170 nM
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| 2 |
EC50 = 248 nM
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| 3 |
Ki = 2865 nM
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CP0455642
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1-[3-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,37S,40S,43R,46S)-43-benzyl-4,19-bis[(2S)-butan-2-yl]-34-(3-carbamimidamidopropyl)-28-[(1S)-1-hydroxyethyl]-22-(hydroxymethyl)-46-(1H-imidazol-5-ylmethyl)-37-(1H-indol-3-ylmethyl)-25,38,47-trimethyl-3,6,12,18,21,24,27,30,33,36,39,42,45,48-tetradecaoxo-50,51-dithia-2,5,11,17,20,23,26,29,32,35,38,41,44,47-tetradecazatetracyclo[29.17.4.07,11.013,17]dopentacontan-40-yl]propyl]guanidine
Show/Hide
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C78H115N23O16S2
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2
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| 1 |
EC50 = 204.17 nM
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| 2 |
Ki = 1949.84 nM
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CP0376382
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(S)-N-((R)-1-((2S,4S)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
Show/Hide
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C38H44N6O3
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2
|
| 1 |
EC50 = 214 nM
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| 2 |
Ki = 529 nM
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CP0388181
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(2S)-2-((3S)-4-{4-Fluoro-N-[(methyloxy)acetyl]-D-phenylalanyl}-2-oxo-3-propyl-1-piperazinyl)-N-methyl-3-(2-naphthalenyl)propanamide
Show/Hide
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C33H39FN4O5
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2
|
| 1 |
EC50 = 215 nM
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| 2 |
Ki = 170 nM
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CP0049442
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(S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)-2-(2-methylsulfanyl-acetylamino)-propionylamino]-3-phenyl-propionylamino}-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
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C35H45N11O5S
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1
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| 1 |
EC50 = 230 nM
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CP0459828
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(2R)-2-amino-3-(4-chlorophenyl)-1-[4-cyclohexyl-4-(1,2,4-triazol-1-ylmethyl)piperidin-1-yl]propan-1-one
Show/Hide
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C23H32ClN5O
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2
|
| 1 |
EC50 = 230 nM
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| 2 |
Ki = 2300 nM
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CP0376441
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(S)-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
Show/Hide
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C38H44N6O3
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2
|
| 1 |
EC50 = 232 nM
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| 2 |
Ki = 86 nM
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CP0423111
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(S)-2-((S)-4-((R)-2-Amino-3-(4-fluorophenyl)propanoyl)-3-ethyl-2-oxopiperazin-1-yl)-N-methyl-3-(naphthalen-2-yl)propanamide
Show/Hide
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C29H33FN4O3
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2
|
| 1 |
EC50 = 237 nM
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| 2 |
Ki = 947 nM
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CP0545381
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(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-4,4-dimethyl-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.2.2]octacosa-1(26),24,27-triene-5-carboxamide
Show/Hide
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C56H74N14O8S2
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2
|
| 1 |
EC50 = 246 nM
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| 2 |
IC50 = 64 nM
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CP0389092
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(2S)-2-[[(2R)-2-[[(2S)-2-acetamido-3-(1H-imidazol-5-yl)propanoyl]amino]-3-[4-(trifluoromethyl)phenyl]propanoyl]amino]-N-[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]hexanamide
Show/Hide
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C35H41F3N8O5
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2
|
| 1 |
EC50 = 252 nM
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| 2 |
IC50 = 90 nM
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CP0389093
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(2S)-2-[[(2R)-2-[[(2S)-2-acetamido-3-(1H-imidazol-5-yl)propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-N-[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]hexanamide
Show/Hide
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C38H44N8O5
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2
|
| 1 |
EC50 = 255 nM
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| 2 |
IC50 > 1000 nM
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CP0376440
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(S)-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)piperidine-2-carboxamide
Show/Hide
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C34H44N6O3
|
2
|
| 1 |
EC50 = 260 nM
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|
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| 2 |
Ki = 156 nM
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CP0425429
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(2R,4R)-1-((R)-2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-3-phenylpropanoyl)-N-(2-guanidinoethyl)-4-(naphthalen-2-ylmethoxy)pyrrolidine-2-carboxamide
Show/Hide
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C34H41N9O4
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2
|
| 1 |
EC50 = 266 nM
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|
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| 2 |
Ki = 703 nM
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CP0423109
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2-{4-[2-Amino-3-(4-fluoro-phenyl)-propionyl]-3-isopropyl-2-oxopiperazin-1-yl}-N-methyl-3-naphthalen-2-yl-propionamide
Show/Hide
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C30H35FN4O3
|
2
|
| 1 |
EC50 = 271 nM
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|
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| 2 |
Ki = 1862 nM
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CP0383564
|
(8S,11S,14S,17R,20S)-17-benzyl-14-[3-(diaminomethylideneamino)propyl]-20-(1H-imidazol-5-ylmethyl)-11-(1H-indol-3-ylmethyl)-6,10,13,16,19,22-hexaoxo-5,9,12,15,18,21-hexazaspiro[3.18]docosane-8-carboxamide
Show/Hide
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C41H51N13O7
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2
|
| 1 |
EC50 = 276 nM
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|
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| 2 |
IC50 > 1000 nM
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CP0376380
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(S)-N-((R)-1-((2S,4S)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)piperidine-2-carboxamide
Show/Hide
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C34H44N6O3
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2
|
| 1 |
EC50 = 286 nM
|
|
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| 2 |
Ki = 1263 nM
|
|
|
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CP0390464
|
(2S)-2-[[(3S,6S,9R,12S,15S,18S)-3-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-9-benzyl-12-[3-(diaminomethylideneamino)propyl]-6-(1H-imidazol-5-ylmethyl)-15-(1H-indol-3-ylmethyl)-4,7,10,13,16-pentaoxo-1,5,8,11,14,17,21,22-octazabicyclo[18.2.1]tricosa-20(23),21-diene-18-carbonyl]amino]-4-methylsulfanylbutanoic acid
Show/Hide
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C51H70N20O9S
|
1
|
| 1 |
EC50 = 290.6 nM
|
|
|
|
CP0190200
|
(S)-5-Guanidino-2-{(S)-2-[(S)-2-(2-hydroxy-acetylamino)-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
|
C34H43N11O6
|
1
|
| 1 |
EC50 = 300 nM
|
|
|
|
CP0403238
|
(2S,5S,8R,11S,14S,17S)-8-benzyl-2,5-dibutyl-11-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
Show/Hide
|
C43H61N11O7
|
2
|
| 1 |
EC50 = 300 nM
|
|
|
| 2 |
IC50 = 250 nM
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|
|
|
CP0423110
|
2-{4-[2-Amino-3-(4-fluoro-phenyl)-propionyl]-3-methyl-2-oxopiperazin-1-yl}-N-methyl-3-naphthalen-2-yl-propionamide
Show/Hide
|
C28H31FN4O3
|
2
|
| 1 |
EC50 = 300 nM
|
|
|
| 2 |
Ki = 2832 nM
|
|
|
|
CP0393258
|
(3S)-3-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]acetyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-(carboxymethylamino)-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C79H103N21O16
|
2
|
| 1 |
EC50 = 300 nM
|
|
|
| 2 |
IC50 = 5 nM
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|
|
|
CP0674615
|
H-Tyr-Val-Nle-Gly-His-D-Nal(2)-Arg-D-Trp-Asp-Arg-Phe-Gly-NH2
Show/Hide
|
C79H104N22O15
|
2
|
| 1 |
EC50 = 300 nM
|
|
|
| 2 |
IC50 = 5 nM
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|
|
|
CP0408810
|
1-[3-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,37S,40S,43R,46S)-43-benzyl-4,19-bis[(2S)-butan-2-yl]-34-(3-carbamimidamidopropyl)-28-[(1S)-1-hydroxyethyl]-22-(hydroxymethyl)-46-(1H-imidazol-5-ylmethyl)-37-(1H-indol-3-ylmethyl)-25,38,41-trimethyl-3,6,12,18,21,24,27,30,33,36,39,42,45,48-tetradecaoxo-50,51-dithia-2,5,11,17,20,23,26,29,32,35,38,41,44,47-tetradecazatetracyclo[29.17.4.07,11.013,17]dopentacontan-40-yl]propyl]guanidine
Show/Hide
|
C78H115N23O16S2
|
2
|
| 1 |
EC50 = 309.03 nM
|
|
|
| 2 |
Ki > 1000 nM
|
|
|
|
CP0376438
|
(S)-2-acetamido-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)-3-phenylpropanamide
Show/Hide
|
C39H46N6O4
|
2
|
| 1 |
EC50 = 313 nM
|
|
|
| 2 |
Ki = 154 nM
|
|
|
|
CP0389096
|
(2S)-2-[[(2R)-2-[[(2S)-2-acetamido-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(4-fluorophenyl)propanoyl]amino]-N-[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]hexanamide
Show/Hide
|
C34H41FN8O5
|
2
|
| 1 |
EC50 = 315 nM
|
|
|
| 2 |
IC50 > 1000 nM
|
|
|
|
CP0404685
|
(2S)-2-acetamido-N-[2-[[2-[[(2R)-1-[[(2S)-5-amino-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]-(4-aminobutyl)amino]-2-oxoethyl]hexanamide
Show/Hide
|
C43H63N11O8
|
2
|
| 1 |
EC50 = 316.23 nM
|
|
|
| 2 |
IC50 = 158.49 nM
|
|
|
|
CP0439061
|
(2S)-2-[[2-[[(2S)-2-acetamidohexanoyl]amino]acetyl]amino]-6-amino-N-[(2R)-1-[[(2S)-1-[[2-[(2-amino-2-oxoethyl)amino]-2-oxoethyl]-(1H-indol-3-ylmethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]hexanamide
Show/Hide
|
C44H65N13O8
|
2
|
| 1 |
EC50 = 316.23 nM
|
|
|
| 2 |
IC50 = 501.19 nM
|
|
|
|
CP0382074
|
(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,4,7,13-tetramethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
|
C58H79N15O9
|
2
|
| 1 |
EC50 = 326 nM
|
|
|
| 2 |
IC50 = 20 nM
|
|
|
|
CP0858767
|
(3R,6R,9S,12R,15S)-12-benzyl-9-(3-carbamimidamidopropyl)-15-(1H-imidazol-5-ylmethyl)-6-(naphthalen-2-ylmethyl)-19-nitro-5,8,11,14,17-pentaoxo-2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17-hexadecahydro-1,4,7,10,13,16-benzothiapentazacyclononadecine-3-carboxamide
Show/Hide
|
C44H48N12O8S
|
2
|
| 1 |
EC50 = 330 nM
|
|
|
| 2 |
IC50 > 8000 nM
|
|
|
|
CP0395362
|
(2R,4R)-1-((R)-2-((S)-2-acetamido-3-(1H-imidazol-4-yl)propanamido)-3-phenylpropanoyl)-N-(2-guanidinoethyl)-4-(naphthalen-2-ylmethoxy)pyrrolidine-2-carboxamide
Show/Hide
|
C36H43N9O5
|
2
|
| 1 |
EC50 = 340 nM
|
|
|
| 2 |
Ki = 824 nM
|
|
|
|
CP0048619
|
2-{(S)-2-[(S)-2-Amino-3-(3H-imidazol-4-yl)-propionylamino]-1-oxo-3-phenyl-propylamino}-5-guanidino-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
|
C32H41N11O4
|
1
|
| 1 |
EC50 = 350 nM
|
|
|
|
CP0050698
|
(S)-2-{(S)-2-[(S)-2-(4-Chloro-benzenesulfonylamino)-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
|
C38H44ClN11O6S
|
1
|
| 1 |
EC50 = 390 nM
|
|
|
|
CP0551926
|
(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-4,4-dimethyl-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.3.1]octacosa-1(27),24(28),25-triene-5-carboxamide
Show/Hide
|
C56H74N14O8S2
|
2
|
| 1 |
EC50 = 435 nM
|
|
|
| 2 |
IC50 = 71 nM
|
|
|
|
CP0089083
|
(S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)-2-propionylamino-propionylamino]-3-phenyl-propionylamino}-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
|
C35H45N11O5
|
1
|
| 1 |
EC50 = 450 nM
|
|
|
|
CP0376220
|
(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-4,7-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
|
C56H75N15O9
|
2
|
| 1 |
EC50 = 463 nM
|
|
|
| 2 |
IC50 = 19.7 nM
|
|
|
|
CP0432200
|
1-[3-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,37S,40S,43R,46S)-43-benzyl-4,19-bis[(2S)-butan-2-yl]-34-(3-carbamimidamidopropyl)-28-[(1S)-1-hydroxyethyl]-22-(hydroxymethyl)-46-(1H-imidazol-5-ylmethyl)-37-(1H-indol-3-ylmethyl)-25-methyl-3,6,12,18,21,24,27,30,33,36,39,42,45,48-tetradecaoxo-50,51-dithia-2,5,11,17,20,23,26,29,32,35,38,41,44,47-tetradecazatetracyclo[29.17.4.07,11.013,17]dopentacontan-40-yl]propyl]guanidine
Show/Hide
|
C76H111N23O16S2
|
2
|
| 1 |
EC50 = 467.74 nM
|
|
|
| 2 |
Ki > 1000 nM
|
|
|
|
CP0378708
|
(2S)-2-[[2-[[(2S)-2-acetamidohexanoyl]amino]acetyl]amino]-6-amino-N-[(2R)-1-[[2-[[2-[(2-amino-2-oxoethyl)amino]-2-oxoethyl]-[2-(1H-indol-3-yl)ethyl]amino]-2-oxoethyl]-[4-(diaminomethylideneamino)butyl]amino]-1-oxo-3-phenylpropan-2-yl]hexanamide
Show/Hide
|
C46H69N13O8
|
2
|
| 1 |
EC50 = 501.19 nM
|
|
|
| 2 |
IC50 = 630.96 nM
|
|
|
|
CP0407278
|
(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-4-methylsulfanylbutanoyl]amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C74H100N22O15S
|
2
|
| 1 |
EC50 = 520 nM
|
|
|
| 2 |
IC50 = 40 nM
|
|
|
|
CP0407277
|
(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-4-methylsulfanylbutanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C73H100N20O15S
|
2
|
| 1 |
EC50 = 521 nM
|
|
|
| 2 |
IC50 = 118 nM
|
|
|
|
CP0044734
|
(S)-2-{(R)-2-[(S)-2-acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid ((S)-1-methylcarbamoyl-2-naphthalen-2-yl-ethyl)-amide
Show/Hide
|
C37H46N10O5
|
2
|
| 1 |
EC50 = 541 nM
|
|
|
| 2 |
Ki = 1195 nM
|
|
|
|
CP0481519
|
N-[(2R)-3-(4-fluorophenyl)-1-[(2S)-4-[(2S)-1-(methylamino)-3-naphthalen-2-yl-1-oxopropan-2-yl]-3-oxo-2-propylpiperazin-1-yl]-1-oxopropan-2-yl]-2,2-dimethylpropanamide
Show/Hide
|
C35H43FN4O4
|
2
|
| 1 |
EC50 = 545 nM
|
|
|
| 2 |
Ki = 827 nM
|
|
|
|
CP0395396
|
(S)-2-acetamido-N1-((R)-1-((2R,4R)-2-(2-guanidinoethylcarbamoyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)pentanediamide
Show/Hide
|
C35H44N8O6
|
2
|
| 1 |
EC50 = 563 nM
|
|
|
| 2 |
Ki = 1488 nM
|
|
|
|
CP0182484
|
(S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)-2-(2-methoxy-acetylamino)-propionylamino]-3-phenyl-propionylamino}-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
|
C35H45N11O6
|
1
|
| 1 |
EC50 = 570 nM
|
|
|
|
CP0376439
|
(S)-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)pyrrolidine-2-carboxamide
Show/Hide
|
C33H42N6O3
|
2
|
| 1 |
EC50 = 593 nM
|
|
|
| 2 |
Ki = 219 nM
|
|
|
|
CP0375709
|
Ac-Nle-c[Asp-His-DNal(2')-trans-4-guanidinyl-Pro-Trp-Lys]-NH2
Show/Hide
|
C54H69N15O9
|
2
|
| 1 |
EC50 = 620 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0403580
|
(2S)-2-[[2-[[(2S)-2-acetamidohexanoyl]amino]acetyl]amino]-6-amino-N-[(2R)-1-[[2-[[2-[(2-amino-2-oxoethyl)amino]-2-oxoethyl]-(1H-indol-3-ylmethyl)amino]-2-oxoethyl]-[3-(diaminomethylideneamino)propyl]amino]-1-oxo-3-phenylpropan-2-yl]hexanamide
Show/Hide
|
C44H65N13O8
|
2
|
| 1 |
EC50 = 630.96 nM
|
|
|
| 2 |
IC50 = 5011.87 nM
|
|
|
|
CP0437027
|
(2S)-2-[[(3S,6S,9R,12S,15S,18S)-9-benzyl-3-[[(2S)-2,6-diaminohexanoyl]amino]-12-[3-(diaminomethylideneamino)propyl]-15-(1H-indol-3-ylmethyl)-6-methyl-4,7,10,13,16-pentaoxo-1,5,8,11,14,17,21,22-octazabicyclo[18.2.1]tricosa-20(23),21-diene-18-carbonyl]amino]-4-methylsulfanylbutanoic acid
Show/Hide
|
C48H68N16O9S
|
1
|
| 1 |
EC50 = 633.1 nM
|
|
|
|
CP0178413
|
(S)-5-Guanidino-2-{(S)-2-[(S)-2-(4-hydroxy-butyrylamino)-3-(3H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
|
C36H47N11O6
|
1
|
| 1 |
EC50 = 640 nM
|
|
|
|
CP0550596
|
(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.2.2]octacosa-1(26),24,27-triene-5-carboxamide
Show/Hide
|
C54H70N14O8S2
|
2
|
| 1 |
EC50 = 645 nM
|
|
|
| 2 |
IC50 = 24 nM
|
|
|
|
CP0099822
|
CAS_72711-43-4
Show/Hide
|
C74H99N21O16S
|
2
|
| 1 |
EC50 = 700 nM
|
|
|
| 2 |
IC50 = 71 nM
|
|
|
|
CP0400880
|
(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,10-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
|
C56H75N15O9
|
2
|
| 1 |
EC50 = 709 nM
|
|
|
| 2 |
IC50 = 795 nM
|
|
|
|
CP0495602
|
(2S)-2-[[(3S,6S,9R,12S,15S,18S)-9-benzyl-3-[[(2S)-2,6-diaminohexanoyl]amino]-12-[3-(diaminomethylideneamino)propyl]-6-(1H-imidazol-5-ylmethyl)-15-(naphthalen-2-ylmethyl)-4,7,10,13,16-pentaoxo-1,5,8,11,14,17,21,22-octazabicyclo[18.2.1]tricosa-20(23),21-diene-18-carbonyl]amino]-4-methylsulfanylbutanoic acid
Show/Hide
|
C53H71N17O9S
|
1
|
| 1 |
EC50 = 721.6 nM
|
|
|
|
CP0378891
|
(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-4,10,13-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
|
C57H77N15O9
|
2
|
| 1 |
EC50 = 753 nM
|
|
|
| 2 |
IC50 = 988 nM
|
|
|
|
CP0408806
|
1-[3-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,37S,40S,43R,46S)-43-benzyl-4,19-bis[(2S)-butan-2-yl]-34-(3-carbamimidamidopropyl)-28-[(1S)-1-hydroxyethyl]-22-(hydroxymethyl)-46-(1H-imidazol-5-ylmethyl)-37-(1H-indol-3-ylmethyl)-25,41-dimethyl-3,6,12,18,21,24,27,30,33,36,39,42,45,48-tetradecaoxo-50,51-dithia-2,5,11,17,20,23,26,29,32,35,38,41,44,47-tetradecazatetracyclo[29.17.4.07,11.013,17]dopentacontan-40-yl]propyl]guanidine
Show/Hide
|
C77H113N23O16S2
|
2
|
| 1 |
EC50 = 758.58 nM
|
|
|
| 2 |
Ki = 7585.78 nM
|
|
|
|
CP0376209
|
(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,7,10,13-tetramethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
|
C58H79N15O9
|
2
|
| 1 |
EC50 = 770 nM
|
|
|
| 2 |
IC50 = 6050 nM
|
|
|
|
CP0652962
|
22-Benzyl-19-(3-guanidino-propyl)-16-(1H-indol-3-ylmethyl)-4,7,15,18,21,24-hexaoxo-docosahydro-3a,8,14,17,20,23-hexaaza-cyclopentacyclotricosene-13-carboxylic acid amide
Show/Hide
|
C41H55N11O7
|
2
|
| 1 |
EC50 = 790 nM
|
|
|
| 2 |
Ki = 390 nM
|
|
|
|
CP0393528
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(2S)-2-[[2-[[2-[acetyl(butyl)amino]acetyl]amino]acetyl]amino]-6-amino-N-[(2R)-1-[[(2S)-1-[[2-[(2-amino-2-oxoethyl)amino]-2-oxoethyl]-(1H-indol-3-ylmethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]hexanamide
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C44H65N13O8
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2
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| 1 |
EC50 = 794.33 nM
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| 2 |
IC50 = 1258.93 nM
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CP0382076
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-4,7,13-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C57H77N15O9
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2
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| 1 |
EC50 = 802 nM
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| 2 |
IC50 = 51 nM
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CP0410710
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(2S)-2-[[(3S,6S,9R,12S,15S,18S)-15-(1-benzothiophen-3-ylmethyl)-9-benzyl-3-[[(2S)-2,6-diaminohexanoyl]amino]-12-[3-(diaminomethylideneamino)propyl]-6-(1H-imidazol-5-ylmethyl)-4,7,10,13,16-pentaoxo-1,5,8,11,14,17,21,22-octazabicyclo[18.2.1]tricosa-20(23),21-diene-18-carbonyl]amino]-4-methylsulfanylbutanoic acid
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C51H69N17O9S2
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1
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| 1 |
EC50 = 821.3 nM
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CP0452991
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(S)-N-((R)-1-((2R,4R)-2-(2-guanidinoethylcarbamoyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
Show/Hide
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C38H43N7O4
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2
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| 1 |
EC50 = 825 nM
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| 2 |
Ki = 4393 nM
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CP0184237
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(S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)-2-methanesulfonylamino-propionylamino]-3-phenyl-propionylamino}-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
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C33H43N11O6S
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1
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| 1 |
EC50 = 840 nM
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CP0388185
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1-Amino-N-((1R)-1-[(4-fluorophenyl)methyl]-2-{(2S)-4-[(1S)-2-(methylamino)-1-(2-naphthalenylmethyl)-2-oxoethyl]-3-oxo-2-propyl-1-piperazinyl}-2-oxoethyl)cyclopropanecarboxamide
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C34H40FN5O4
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2
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| 1 |
EC50 = 848 nM
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| 2 |
Ki = 434 nM
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CP0441673
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1-(3-((2S,4R)-1-((R)-2-amino-3-phenylpropanoyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-2-yl)propyl)guanidine
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C28H35N5O2
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2
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| 1 |
EC50 = 871 nM
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| 2 |
Ki = 1244 nM
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CP0547334
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(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.3.1]octacosa-1(27),24(28),25-triene-5-carboxamide
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C54H70N14O8S2
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2
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| 1 |
EC50 = 902 nM
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| 2 |
IC50 = 32 nM
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CP0410091
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-phenylpropanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-aminooxy-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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C77H103N21O16
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2
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| 1 |
EC50 = 951 nM
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| 2 |
IC50 = 6 nM
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CP0421225
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N-[(2R)-3-(4-fluorophenyl)-1-[(2S)-4-[(2S)-1-(methylamino)-3-naphthalen-2-yl-1-oxopropan-2-yl]-3-oxo-2-propylpiperazin-1-yl]-1-oxopropan-2-yl]pyridine-2-carboxamide
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C36H38FN5O4
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2
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| 1 |
EC50 = 984 nM
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| 2 |
Ki = 215 nM
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CP0103609
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9-Benzyl-12-(3H-imidazol-4-ylmethyl)-3-(1H-indol-3-ylmethyl)-6-methyl-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18hexaaza-cyclotricosane-23-carboxylic acid amide
Show/Hide
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C39H48N10O7
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2
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| 1 |
EC50 = 1000 nM
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| 2 |
Ki = 370 nM
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CP0376106
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]acetyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-(carboxymethylamino)-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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C75H101N21O16
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2
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| 1 |
EC50 = 1000 nM
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| 2 |
IC50 = 62 nM
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CP0408815
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2-[(1R,4S,7S,13S,16S,19R,22S,25S,28R,31S,37S,40S,46S)-19,46-dibenzyl-4-[(2S)-butan-2-yl]-16,31-bis(3-carbamimidamidopropyl)-25-[(1R)-1-hydroxyethyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-17-methyl-3,6,12,15,18,21,24,27,30,33,36,39,45,48-tetradecaoxo-50,51-dithia-2,5,11,14,17,20,23,26,29,32,35,38,44,47-tetradecazatetracyclo[26.20.4.07,11.040,44]dopentacontan-37-yl]acetic acid
Show/Hide
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C80H109N23O17S2
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2
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| 1 |
EC50 = 1000 nM
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| 2 |
Ki > 1000 nM
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CP0408822
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1-[3-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,37S,40S,43R,46S)-43-benzyl-4,19-bis[(2S)-butan-2-yl]-34-(3-carbamimidamidopropyl)-28-[(1S)-1-hydroxyethyl]-22-(hydroxymethyl)-46-(1H-imidazol-5-ylmethyl)-37-(1H-indol-3-ylmethyl)-25,38,41,47-tetramethyl-3,6,12,18,21,24,27,30,33,36,39,42,45,48-tetradecaoxo-50,51-dithia-2,5,11,17,20,23,26,29,32,35,38,41,44,47-tetradecazatetracyclo[29.17.4.07,11.013,17]dopentacontan-40-yl]propyl]guanidine
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C79H117N23O16S2
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2
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| 1 |
EC50 = 1000 nM
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| 2 |
Ki = 3981.07 nM
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CP0430807
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N-[(2R)-3-(4-fluorophenyl)-1-[(2S)-4-[(2S)-1-(methylamino)-3-naphthalen-2-yl-1-oxopropan-2-yl]-3-oxo-2-propylpiperazin-1-yl]-1-oxopropan-2-yl]-1,3-thiazole-4-carboxamide
Show/Hide
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C34H36FN5O4S
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2
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| 1 |
EC50 = 1100 nM
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| 2 |
Ki = 428 nM
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CP0378892
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-7,10,13-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C57H77N15O9
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2
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| 1 |
EC50 = 1130 nM
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| 2 |
IC50 = 336 nM
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CP0376385
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(S)-2-acetamido-N-((R)-1-((2R,4S)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)-3-(1H-imidazol-4-)propanamide
Show/Hide
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C36H44N8O4
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2
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| 1 |
EC50 = 1134 nM
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| 2 |
Ki = 1958 nM
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CP0446498
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(S)-2-acetamido-N-((R)-1-((2R,4S)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)-3-(4-hydroxyphenyl)propanamide
Show/Hide
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C39H46N6O5
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2
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| 1 |
EC50 = 1171 nM
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| 2 |
Ki = 2884 nM
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CP0485886
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(2R,4R)-1-((R)-2-((S)-2-acetamido-3-(4-hydroxyphenyl)propanamido)-3-phenylpropanoyl)-N-(2-guanidinoethyl)-4-(naphthalen-2-ylmethoxy)pyrrolidine-2-carboxamide
Show/Hide
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C39H45N7O6
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2
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| 1 |
EC50 = 1218 nM
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| 2 |
Ki = 501 nM
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CP0442508
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N-[(2R)-1-[(2S,4R)-2-[3-(diaminomethylideneamino)propyl]-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl]-1-oxo-3-phenylpropan-2-yl]acetamide
Show/Hide
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C30H37N5O3
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2
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| 1 |
EC50 = 1384 nM
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| 2 |
Ki = 289 nM
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CP0376246
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,4,7,10,13-pentamethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C59H81N15O9
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2
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| 1 |
EC50 = 1400 nM
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| 2 |
IC50 = 5820 nM
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CP0422296
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(S)-N-((R)-1-((2R,4R)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
Show/Hide
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C38H44N6O3
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2
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| 1 |
EC50 = 1474 nM
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| 2 |
Ki = 8102 nM
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CP0408813
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2-[(1R,4S,7S,13S,16S,19R,22S,25S,28R,31S,37S,40S,46S)-19,46-dibenzyl-4-[(2S)-butan-2-yl]-16,31-bis(3-carbamimidamidopropyl)-25-[(1R)-1-hydroxyethyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-3,6,12,15,18,21,24,27,30,33,36,39,45,48-tetradecaoxo-50,51-dithia-2,5,11,14,17,20,23,26,29,32,35,38,44,47-tetradecazatetracyclo[26.20.4.07,11.040,44]dopentacontan-37-yl]acetic acid
Show/Hide
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C79H107N23O17S2
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2
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| 1 |
EC50 = 1479.11 nM
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| 2 |
Ki = 17782.79 nM
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CP0432500
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(2S,5R,8R,11S,14S,17S)-5-(3-amino-3-oxopropyl)-8-benzyl-2-butyl-11-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
Show/Hide
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C42H58N12O8
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2
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| 1 |
EC50 = 1700 nM
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| 2 |
IC50 = 270 nM
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CP0374869
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(S)-N-((R)-1-((2R,4R)-2-(2-guanidinoethylcarbamoyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)piperidine-2-carboxamide
Show/Hide
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C34H43N7O4
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2
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| 1 |
EC50 = 1774 nM
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| 2 |
Ki = 3852 nM
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CP0376207
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,10,13-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C57H77N15O9
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2
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| 1 |
EC50 = 1790 nM
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| 2 |
IC50 = 13.7 nM
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CP0388955
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,7,10-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C57H77N15O9
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2
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| 1 |
EC50 = 1810 nM
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| 2 |
IC50 = 8 nM
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CP0376211
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-4,7,10,13-tetramethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C58H79N15O9
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2
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| 1 |
EC50 = 1950 nM
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| 2 |
IC50 = 657 nM
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CP0395139
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(2S)-2-[[2-[[(2S)-2-acetamidohexanoyl]amino]acetyl]amino]-6-amino-N-[(2R)-1-[[(2S)-1-[[2-[(2-amino-2-oxoethyl)amino]-2-oxoethyl]-[2-(1H-indol-3-yl)ethyl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]hexanamide
Show/Hide
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C45H67N13O8
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2
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| 1 |
EC50 = 1995.26 nM
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| 2 |
IC50 = 7943.28 nM
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CP0395141
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(2S)-2-[[(2R)-2-[[2-[[2-[[2-[acetyl(butyl)amino]acetyl]amino]acetyl]-(4-aminobutyl)amino]acetyl]amino]-3-phenylpropanoyl]amino]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-5-(diaminomethylideneamino)pentanamide
Show/Hide
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C44H65N13O8
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2
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| 1 |
EC50 = 1995.26 nM
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| 2 |
IC50 = 1258.93 nM
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CP0848656
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(S)-2-((R)-2-((S)-4-acetamido-3-oxo-4,5-dihydro-1H-benzo[c]azepin-2(3H)-yl)-3-phenylpropanamido)-N-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-5-guanidinopentanamide
Show/Hide
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C38H45N9O5
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2
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| 1 |
EC50 = 2000 nM
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| 2 |
IC50 > 2000 nM
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CP0442509
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N-[(2R)-1-[(2S,4R)-2-[3-(diaminomethylideneamino)propyl]-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl]-1-oxo-3-phenylpropan-2-yl]-3-phenylpropanamide
Show/Hide
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C37H43N5O3
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2
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| 1 |
EC50 = 2051 nM
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| 2 |
Ki = 403 nM
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CP0408821
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1-[3-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,37S,40S,43S,46S)-43-benzyl-4,19-bis[(2S)-butan-2-yl]-34-(3-carbamimidamidopropyl)-28-[(1S)-1-hydroxyethyl]-22-(hydroxymethyl)-46-(1H-imidazol-5-ylmethyl)-37-(1H-indol-3-ylmethyl)-25-methyl-3,6,12,18,21,24,27,30,33,36,39,42,45,48-tetradecaoxo-50,51-dithia-2,5,11,17,20,23,26,29,32,35,38,41,44,47-tetradecazatetracyclo[29.17.4.07,11.013,17]dopentacontan-40-yl]propyl]guanidine
Show/Hide
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C76H111N23O16S2
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2
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| 1 |
EC50 = 2137.96 nM
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| 2 |
Ki = 23442.29 nM
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CP0388943
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,7,13-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C57H77N15O9
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2
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| 1 |
EC50 = 2370 nM
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| 2 |
IC50 = 2.5 nM
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CP0865305
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(S)-2-((R)-2-((S)-4-acetamido-3-oxo-4,5-dihydroazepino[3,4-b]indol-2(1H,3H,10H)-yl)-3-(4-bromophenyl)propanamido)-N-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-5-guanidinopentanamide
Show/Hide
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C40H45BrN10O5
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2
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| 1 |
EC50 = 2435 nM
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| 2 |
IC50 = 100 nM
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CP0376449
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N-[(2R)-1-[(2R,4R)-2-[2-(diaminomethylideneamino)ethylcarbamoyl]-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl]-1-oxo-3-phenylpropan-2-yl]piperidine-4-carboxamide
Show/Hide
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C34H43N7O4
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2
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| 1 |
EC50 = 2474 nM
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| 2 |
Ki = 3177 nM
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CP0375708
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Ac-Nle-c[Asp-cis-4-guanidinyl-Pro-DPhe-Arg-Trp-Lys]-NH2
Show/Hide
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C50H72N16O9
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2
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| 1 |
EC50 = 2500 nM
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| 2 |
IC50 = 2.8 nM
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CP0432642
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2-[(1R,4S,7S,13S,16S,19R,22S,25S,28R,31S,37S,40S,46S)-19,46-dibenzyl-4-[(2S)-butan-2-yl]-16,31-bis(3-carbamimidamidopropyl)-25-[(1R)-1-hydroxyethyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-14-methyl-3,6,12,15,18,21,24,27,30,33,36,39,45,48-tetradecaoxo-50,51-dithia-2,5,11,14,17,20,23,26,29,32,35,38,44,47-tetradecazatetracyclo[26.20.4.07,11.040,44]dopentacontan-37-yl]acetic acid
Show/Hide
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C80H109N23O17S2
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2
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| 1 |
EC50 = 2691.53 nM
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| 2 |
Ki = 53703.18 nM
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CP0441512
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3-[(2S,5S,8R,11S,14S,17S)-2-butyl-17-carbamoyl-11-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-8-(naphthalen-2-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicos-5-yl]propanoic acid
Show/Hide
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C46H59N11O9
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2
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| 1 |
EC50 = 2800 nM
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| 2 |
IC50 = 140 nM
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CP0495915
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(S)-2-acetamido-N1-((R)-1-((2R,4S)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)pentanediamide
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C32H41N7O4
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2
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| 1 |
EC50 = 2986 nM
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| 2 |
Ki = 29064 nM
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CP0394002
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(S)-N-((R)-1-((2R,4S)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
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C38H44N6O3
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2
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| 1 |
EC50 = 3152 nM
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| 2 |
Ki = 4180 nM
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CP0496851
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(2S)-2-[[2-[[2-[acetyl(butyl)amino]acetyl]amino]acetyl]amino]-6-amino-N-[(2R)-1-[[(2S)-1-[[2-[(2-amino-2-oxoethyl)amino]-2-oxoethyl]-[2-(1H-indol-3-yl)ethyl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]hexanamide
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C45H67N13O8
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1
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| 1 |
EC50 = 3162.28 nM
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CP0422298
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(S)-2-acetamido-N-((R)-1-((2R,4R)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)-3-(1H-imidazol-4-yl)propanamide
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C36H44N8O4
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2
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| 1 |
EC50 = 3720 nM
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| 2 |
Ki = 7226 nM
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CP0382077
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,4,7,10-tetramethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
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C58H79N15O9
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2
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| 1 |
EC50 = 3930 nM
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| 2 |
IC50 = 1270 nM
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CP0404666
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(2S)-2-acetamido-N-[2-[4-aminobutyl-[2-[[(2R)-1-[[2-[[2-[(2-amino-2-oxoethyl)amino]-2-oxoethyl]-[2-(1H-indol-3-yl)ethyl]amino]-2-oxoethyl]-[3-(diaminomethylideneamino)propyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]hexanamide
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C45H67N13O8
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2
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| 1 |
EC50 = 3981.07 nM
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| 2 |
IC50 = 3981.07 nM
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CP0490820
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(2S)-2-[[2-[[(2S)-2-acetamidohexanoyl]amino]acetyl]amino]-6-amino-N-[(2R)-1-[[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]-[3-(diaminomethylideneamino)propyl]amino]-1-oxo-3-phenylpropan-2-yl]hexanamide
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C44H65N13O8
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2
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| 1 |
EC50 = 3981.07 nM
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| 2 |
IC50 = 5011.87 nM
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CP0432515
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3-[(2S,5R,8R,11S,14S,17S)-8-benzyl-2-butyl-17-carbamoyl-11-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicos-5-yl]propanoic acid
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C42H57N11O9
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2
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| 1 |
EC50 = 4300 nM
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| 2 |
IC50 = 1200 nM
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CP0392780
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(2S)-2-acetamido-N-[2-[4-aminobutyl-[2-[[(2R)-1-[[(2S)-1-[[2-[(2-amino-2-oxoethyl)amino]-2-oxoethyl]-(1H-indol-3-ylmethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]hexanamide
Show/Hide
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C44H65N13O8
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2
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| 1 |
EC50 = 5011.87 nM
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| 2 |
IC50 = 794.33 nM
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CP0916344
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2-{(S)-2-[2-(Acetyl-butyl-amino)-acetylamino]-1-oxo-ethylamino}-6-amino-hexanoic acid {1-[{[1-(carbamoylmethyl-carbamoyl)-2-(1H-indol-3-yl)-ethylcarbamoyl]-methyl}-(3-guanidino-propyl)-carbamoyl]-2-phenyl-ethyl}-amide
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C44H65N13O8
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1
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| 1 |
EC50 = 5011.87 nM
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CP0382072
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,4,10,13-tetramethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
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C58H79N15O9
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2
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| 1 |
EC50 = 5180 nM
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| 2 |
IC50 = 1670 nM
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CP0396381
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2-[(1R,4S,7S,13S,16S,19R,22S,25S,28R,31S,37S,40S,46S)-19,46-dibenzyl-4-[(2S)-butan-2-yl]-16,31-bis(3-carbamimidamidopropyl)-25-[(1R)-1-hydroxyethyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-17,23-dimethyl-3,6,12,15,18,21,24,27,30,33,36,39,45,48-tetradecaoxo-50,51-dithia-2,5,11,14,17,20,23,26,29,32,35,38,44,47-tetradecazatetracyclo[26.20.4.07,11.040,44]dopentacontan-37-yl]acetic acid
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C81H111N23O17S2
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2
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| 1 |
EC50 = 5370.32 nM
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| 2 |
Ki = 24547.09 nM
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CP0404667
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(2R)-2-[[2-[[2-[[2-[acetyl(butyl)amino]acetyl]amino]acetyl]-(4-aminobutyl)amino]acetyl]amino]-N-[2-[[2-[(2-amino-2-oxoethyl)amino]-2-oxoethyl]-[2-(1H-indol-3-yl)ethyl]amino]-2-oxoethyl]-N-[3-(diaminomethylideneamino)propyl]-3-phenylpropanamide
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C45H67N13O8
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2
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| 1 |
EC50 = 6309.57 nM
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| 2 |
IC50 = 3981.07 nM
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CP0404671
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(2S)-2-acetamido-N-[2-[4-aminobutyl-[2-[[(2R)-1-[[2-[[2-[(2-amino-2-oxoethyl)amino]-2-oxoethyl]-(1H-indol-3-ylmethyl)amino]-2-oxoethyl]-[3-(diaminomethylideneamino)propyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]hexanamide
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C44H65N13O8
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1
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| 1 |
EC50 = 6309.57 nM
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CP0408819
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1-[3-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,37S,40S,43R,46S)-43-benzyl-4,19-bis[(2S)-butan-2-yl]-34-(3-carbamimidamidopropyl)-28-[(1S)-1-hydroxyethyl]-22-(hydroxymethyl)-46-(1H-imidazol-5-ylmethyl)-37-(1H-indol-3-ylmethyl)-25,41,47-trimethyl-3,6,12,18,21,24,27,30,33,36,39,42,45,48-tetradecaoxo-50,51-dithia-2,5,11,17,20,23,26,29,32,35,38,41,44,47-tetradecazatetracyclo[29.17.4.07,11.013,17]dopentacontan-40-yl]propyl]guanidine
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C78H115N23O16S2
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2
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| 1 |
EC50 = 6918.31 nM
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| 2 |
Ki = 28183.83 nM
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CP0408820
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2-[(1R,4S,7S,13S,16S,19R,22S,25S,28R,31S,37S,40S,46S)-19,46-dibenzyl-4-[(2S)-butan-2-yl]-16,31-bis(3-carbamimidamidopropyl)-25-[(1R)-1-hydroxyethyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-23-methyl-3,6,12,15,18,21,24,27,30,33,36,39,45,48-tetradecaoxo-50,51-dithia-2,5,11,14,17,20,23,26,29,32,35,38,44,47-tetradecazatetracyclo[26.20.4.07,11.040,44]dopentacontan-37-yl]acetic acid
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C80H109N23O17S2
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2
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| 1 |
EC50 = 7413.1 nM
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| 2 |
Ki = 38904.51 nM
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CP0408808
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1-[3-[(1R,4S,7S,13S,19S,22S,25S,28S,31R,34S,37S,40S,43R,46S)-43-benzyl-4,19-bis[(2S)-butan-2-yl]-34-(3-carbamimidamidopropyl)-28-[(1S)-1-hydroxyethyl]-22-(hydroxymethyl)-46-(1H-imidazol-5-ylmethyl)-37-(1H-indol-3-ylmethyl)-25,47-dimethyl-3,6,12,18,21,24,27,30,33,36,39,42,45,48-tetradecaoxo-50,51-dithia-2,5,11,17,20,23,26,29,32,35,38,41,44,47-tetradecazatetracyclo[29.17.4.07,11.013,17]dopentacontan-40-yl]propyl]guanidine
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C77H113N23O16S2
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2
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| 1 |
EC50 = 8709.64 nM
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| 2 |
Ki = 24547.09 nM
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CP0103613
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6-(3-Guanidino-propyl)-12-(3H-imidazol-4-ylmethyl)-3-(1H-indol-3-ylmethyl)-9-methyl-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18hexaaza-cyclotricosane-23-carboxylic acid amide
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C36H51N13O7
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1
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| 1 |
EC50 > 10000 nM
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CP0149707
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8-(3-Guanidino-propyl)-2-(3H-imidazol-4-ylmethyl)-11-(1H-indol-3-ylmethyl)-5-naphthalen-2-ylmethyl-3,6,9,12,20,24-hexaoxo-1,4,7,10,13,19hexaaza-cyclotetracosane-14-carboxylic acid amide
Show/Hide
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C47H59N13O7
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
Ki = 5.9 nM
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CP0371887
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4-[(3S,8aS)-3-benzyl-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-N-[2-(1H-indol-3-yl)ethyl]-4-oxobutanamide
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C28H34N4O2
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0371892
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1-((3R,8aS)-3-benzyl-hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-3-(1H-indol-3-yl)propan-1-one
Show/Hide
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C25H29N3O
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 1.2 nM
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CP0371896
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4-[(3R,8aS)-3-benzyl-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-N-[2-(1H-indol-3-yl)ethyl]-4-oxobutanamide
Show/Hide
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C28H34N4O2
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0381774
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N-[(2S)-1-[(3S,8aS)-3-benzyl-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-3-(1H-indol-3-yl)propanamide
Show/Hide
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C31H41N7O2
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0381776
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1-((3R,8aS)-3-benzyl-hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-2-phenylethanone
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C22H26N2O
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 5 nM
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CP0381777
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N-[6-[(3S,8aS)-3-benzyl-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-6-oxohexyl]-3-(1H-indol-3-yl)propanamide
Show/Hide
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C31H40N4O2
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0381817
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1-((3S,8aS)-3-benzyl-hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-2-phenylethanone
Show/Hide
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C22H26N2O
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 350 nM
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CP0424734
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1-((3S,8aS)-3-benzyl-hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-3-(1H-indol-3-yl)propan-1-one
Show/Hide
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C25H29N3O
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0378867
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(2S,5S,8R,11S,14S,17S)-2-butyl-11-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-8-(naphthalen-2-ylmethyl)-3,6,9,12,15,20-hexaoxo-5-propan-2-yl-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
Show/Hide
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C46H61N11O7
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3
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 1.7 nM
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| 3 |
Kd = 3.981 nM
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CP0403235
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(2S,5R,8R,11S,14S,17S)-2-butyl-5,11-bis[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-8-(naphthalen-2-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
Show/Hide
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C47H64N14O7
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 2.6 nM
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CP0403236
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2-[(2S,5S,8R,11S,14S,17S)-8-benzyl-2-butyl-17-carbamoyl-11-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicos-5-yl]acetic acid
Show/Hide
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C41H55N11O9
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0403239
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(3S,8S,11S,14S,17R,20R)-17-benzyl-3-butyl-14-[3-(diaminomethylideneamino)propyl]-11-(1H-indol-3-ylmethyl)-2,5,10,13,16,19-hexaoxo-1,4,9,12,15,18-hexazabicyclo[18.3.0]tricosane-8-carboxamide
Show/Hide
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C42H57N11O7
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 2700 nM
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CP0432501
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2-[(2S,5R,8R,11S,14S,17S)-2-butyl-17-carbamoyl-11-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-8-(naphthalen-2-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicos-5-yl]acetic acid
Show/Hide
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C45H57N11O9
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 820 nM
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CP0432503
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(2S,5S,8R,11S,14S,17S)-2,5-dibutyl-11-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-8-(naphthalen-2-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
Show/Hide
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C47H63N11O7
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 6 nM
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CP0432514
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(2S,5S,8R,11S,14S,17S)-5-(3-amino-3-oxopropyl)-2-butyl-11-[3-(diaminomethylideneamino)propyl]-14-(1H-indol-3-ylmethyl)-8-(naphthalen-2-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
Show/Hide
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C46H60N12O8
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 1.4 nM
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CP0441513
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(2S,5S,8R,11S,14S,17S)-2-butyl-11-[3-(diaminomethylideneamino)propyl]-5-(1H-imidazol-5-ylmethyl)-14-(1H-indol-3-ylmethyl)-8-(naphthalen-2-ylmethyl)-3,6,9,12,15,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-17-carboxamide
Show/Hide
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C47H59N13O7
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 12 nM
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CP0442492
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(3S,8S,11S,14S,17R,20S)-3-butyl-14-[3-(diaminomethylideneamino)propyl]-11-(1H-indol-3-ylmethyl)-17-(naphthalen-2-ylmethyl)-2,5,10,13,16,19-hexaoxo-1,4,9,12,15,18-hexazabicyclo[18.3.0]tricosane-8-carboxamide
Show/Hide
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C46H59N11O7
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 13 nM
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CP0376105
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]acetyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-aminooxy-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
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C82H106N20O16
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 3000 nM
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CP0444828
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(2R,5S,8S,11S,19S)-19-[(2S)-2-aminohexanamido]-2-benzyl-5-(3-carbamimidamidopropyl)-8-(1H-indol-3-ylmethyl)-3,6,9,17,20,31-hexaoxo-1,4,7,10,16,21-hexaazatricyclo[20.8.1.0^{24,29}]hentriaconta-24(29),25,27-triene-11-carboxamide
Show/Hide
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C52H69N13O8
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 50 nM
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CP0462965
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(S)-3-((R)-2-acetamidohexanamido)-4-(2-((S)-1-((S)-1-((S)-1-((S)-1,6-diamino-1-oxohexan-2-ylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-5-guanidino-1-oxopentan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-3-oxo-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-ylamino)
Show/Hide
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C54H73N13O10
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0485356
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(2R,5S,8S,11S,19S)-19-[(2S)-2-aminohexanamido]-5-(3-carbamimidamidopropyl)-8-(1H-indol-3-ylmethyl)-2-(naphthalen-2-ylmethyl)-3,6,9,17,20,31-hexaoxo-1,4,7,10,16,21-hexaazatricyclo[20.8.1.0^{24,29}]hentriaconta-24(29),25,27-triene-11-carboxamide
Show/Hide
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C56H71N13O8
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 43 nM
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CP0376205
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-10-methyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C55H73N15O9
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2
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| 1 |
EC50 > 10000 nM
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|
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| 2 |
IC50 = 27.4 nM
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CP0376215
|
(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,4,10-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C57H77N15O9
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2
|
| 1 |
EC50 > 10000 nM
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|
|
| 2 |
IC50 = 147 nM
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CP0376219
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,13-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C56H75N15O9
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2
|
| 1 |
EC50 > 10000 nM
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|
|
| 2 |
IC50 = 24.9 nM
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|
|
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CP0378890
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,4,7-trimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C57H77N15O9
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3
|
| 1 |
EC50 > 10000 nM
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|
|
| 2 |
IC50 = 9.7 nM
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|
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| 3 |
Kd = 3.162 nM
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CP0382073
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-7,13-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C56H75N15O9
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3
|
| 1 |
EC50 > 10000 nM
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|
|
| 2 |
IC50 = 15.3 nM
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|
|
| 3 |
Kd = 6.31 nM
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CP0382079
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-4-methyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
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C55H73N15O9
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2
|
| 1 |
EC50 > 10000 nM
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|
|
| 2 |
IC50 = 20.4 nM
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|
|
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CP0382100
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-13-methyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
|
C55H73N15O9
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2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 3.2 nM
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|
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CP0388945
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(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
|
C54H71N15O9
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2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 3.74 nM
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|
|
|
CP0388946
|
(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1,7-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
|
C56H75N15O9
|
3
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 1.6 nM
|
|
|
| 3 |
Kd = 0.7943 nM
|
|
|
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CP0400431
|
(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-7-methyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
|
C55H73N15O9
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 47.4 nM
|
|
|
|
CP0400881
|
(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-10,13-dimethyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
|
C56H75N15O9
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 547 nM
|
|
|
|
CP0400882
|
(3S,6S,9R,12S,15S,23S)-15-[[(2R)-2-acetamidohexanoyl]amino]-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-1-methyl-9-(naphthalen-2-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
Show/Hide
|
C55H73N15O9
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2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 23 nM
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|
|
|
CP0454325
|
(2R)-2-amino-N-[(2R)-1-cyclohexyl-5-(diaminomethylideneamino)pentan-2-yl]-3-(4-fluorophenyl)propanamide
Show/Hide
|
C21H34FN5O
|
2
|
| 1 |
EC50 > 15000 nM
|
|
|
| 2 |
Ki = 9100 nM
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|
|
|
CP0034706
|
(S)-2-{(R)-2-[(S)-2-acetylamino-3-(4-hydroxy-phenyl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid ((S)-1-methylcarbamoyl-2-naphthalen-2-yl-ethyl)-amide
Show/Hide
|
C40H48N8O6
|
2
|
| 1 |
EC50 = 20000 nM
|
|
|
| 2 |
Ki = 1727 nM
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|
|
|
CP0135132
|
(2S)-2-[[(2R)-2-amino-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)-N-[(2S)-1-(methylamino)-3-naphthalen-2-yl-1-oxopropan-2-yl]pentanamide
Show/Hide
|
C29H37N7O3
|
2
|
| 1 |
EC50 = 20000 nM
|
|
|
| 2 |
Ki = 22562 nM
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|
|
|
CP0376435
|
(S)-2-acetamido-N1-((R)-1-((2R,4R)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)pentanediamide
Show/Hide
|
C32H41N7O4
|
2
|
| 1 |
EC50 = 20000 nM
|
|
|
| 2 |
Ki = 15358 nM
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|
|
|
CP0376436
|
(S)-N-((R)-1-((2R,4R)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)piperidine-2-carboxamide
Show/Hide
|
C34H44N6O3
|
2
|
| 1 |
EC50 = 20000 nM
|
|
|
| 2 |
Ki = 7441 nM
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|
|
|
CP0376437
|
(S)-2-acetamido-N-((R)-1-((2R,4R)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)-3-(4-hydroxyphenyl)propanamide
Show/Hide
|
C39H46N6O5
|
2
|
| 1 |
EC50 = 20000 nM
|
|
|
| 2 |
Ki = 19213 nM
|
|
|
|
CP0390604
|
(S)-N-((R)-1-((2R,4S)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)piperidine-2-carboxamide
Show/Hide
|
C34H44N6O3
|
2
|
| 1 |
EC50 = 20000 nM
|
|
|
| 2 |
Ki = 7163 nM
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|
|
|
CP0393623
|
(3S)-3-amino-4-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-6-amino-1-[[(1R,6aR,7S,10S,13S,16S,19S,22S,25S,31S,34S,37S,43S,46S,49S,55S,58S,61R,66R,69S,72S,75S,84S,88R,90S,93S,96S,99S)-19,37,49-tris(4-aminobutyl)-13,58-bis(2-amino-2-oxoethyl)-25,72-bis(3-amino-3-oxopropyl)-84-benzyl-93-(3-carbamimidamidopropyl)-46-(carboxymethyl)-6a-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]-16,31-bis[(1R)-1-hydroxyethyl]-10,96,99-tris(hydroxymethyl)-75-(1H-imidazol-5-ylmethyl)-22,69,90-tris(2-methylpropyl)-a,2,8,8a,11,14,17,20,23,26,29,32,35,38,44,47,50,56,59,67,70,73,76,79,82,85,87,91,94,97-triacontaoxo-3a,4a,10a,11a,63,64-hexathia-1a,3,7a,9,12,15,18,21,24,27,30,33,36,39,45,48,51,57,60,68,71,74,77,80,83,86,89,92,95,98-triacontazahexacyclo[59.40.7.434,88.03,7.039,43.051,55]dodecahectan-66-yl]amino]-1-oxohexan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C165H262N52O51S6
|
1
|
| 1 |
EC50 = 22000 nM
|
|
|
|
CP0404966
|
(2R)-2-amino-N-[(2S)-5-(diaminomethylideneamino)-1-oxo-1-piperidin-1-ylpentan-2-yl]-3-(4-fluorophenyl)propanamide
Show/Hide
|
C20H31FN6O2
|
2
|
| 1 |
EC50 > 25000 nM
|
|
|
| 2 |
Ki > 100000 nM
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|
|
|
CP0432645
|
2-[(1R,4S,7S,13S,16S,19R,22S,25S,28R,31S,37S,40S,46S)-19,46-dibenzyl-4-[(2S)-butan-2-yl]-16,31-bis(3-carbamimidamidopropyl)-25-[(1R)-1-hydroxyethyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-14,23-dimethyl-3,6,12,15,18,21,24,27,30,33,36,39,45,48-tetradecaoxo-50,51-dithia-2,5,11,14,17,20,23,26,29,32,35,38,44,47-tetradecazatetracyclo[26.20.4.07,11.040,44]dopentacontan-37-yl]acetic acid
Show/Hide
|
C81H111N23O17S2
|
2
|
| 1 |
EC50 = 26915.35 nM
|
|
|
| 2 |
Ki = 42657.95 nM
|
|
|
|
CP0096571
|
9-Benzyl-6-(3-guanidino-propyl)-3-(1H-indol-3-ylmethyl)-12-methyl-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18hexaaza-cyclotricosane-23-carboxylic acid amide
Show/Hide
|
C39H53N11O7
|
2
|
| 1 |
EC50 = 42000 nM
|
|
|
| 2 |
Ki = 1400 nM
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|
|
|
CP0382252
|
(2R)-2-amino-N-[3-cyclohexyl-4-(1,2,4-triazol-1-yl)butyl]-3-(4-fluorophenyl)propanamide
Show/Hide
|
C21H30FN5O
|
2
|
| 1 |
EC50 > 50000 nM
|
|
|
| 2 |
Ki = 4500 nM
|
|
|
|
CP0372759
|
(2R)-2-amino-N-[(2S)-5-(diaminomethylideneamino)-1-piperidin-1-ylpentan-2-yl]-3-(4-fluorophenyl)propanamide
Show/Hide
|
C20H33FN6O
|
2
|
| 1 |
EC50 > 100000 nM
|
|
|
| 2 |
Ki > 100000 nM
|
|
|
|
CP0404967
|
(2R)-2-amino-N-[(2R)-5-(diaminomethylideneamino)-1-phenylpentan-2-yl]-3-(4-fluorophenyl)propanamide
Show/Hide
|
C21H28FN5O
|
2
|
| 1 |
EC50 > 100000 nM
|
|
|
| 2 |
Ki = 3500 nM
|
|
|
|
CP0389236
|
(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[2-[[(2S)-5-amino-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[(2S)-2-[[(2S,3S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-6-amino-1-[[(2S,3S)-1-[[(2S)-5-amino-1-[[2-[[(2S,3R)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2R)-1-[[(2R)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-1-oxohexan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-2-oxoethyl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-2-oxoethyl]amino]-1,5-dioxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxo-3-sulfanylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C167H263N49O49S6
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0396404
|
(3S)-3-amino-4-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2R)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[2-[[2-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[(2S)-2-[[(2S)-1-[[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-5-amino-1-[[2-[[(2S,3R)-1-[[(2R)-1-[[(2S)-6-amino-1-[(2S)-2-[[(2S)-1-[[(2S)-6-amino-1-[(2S)-2-[[(2S)-4-amino-1-[[(2R)-1-[[(2R)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-1,4-dioxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-2-oxoethyl]amino]-1,5-dioxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxo-3-sulfanylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C165H268N52O51S6
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0436883
|
(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(aR,1R,6S,9S,12S,15S,18S,21S,24S,30S,33R,36S,39S,45S,48S,51S,54R,59R,62S,65S,68S,77S,80R,83S,86R,89S,92S)-18,45,51-tris(4-aminobutyl)-24-(3-amino-3-oxopropyl)-12-benzyl-9,21-bis[(2S)-butan-2-yl]-39-(3-carbamimidamidopropyl)-77-(2-carboxyethyl)-a-[[(2S)-1,6-diamino-1-oxohexan-2-yl]carbamoyl]-15,30-bis[(1R)-1-hydroxyethyl]-65,68,89-tris(hydroxymethyl)-36,86-bis[(4-hydroxyphenyl)methyl]-48,92-dimethyl-83-(2-methylpropyl)-2a,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,60,63,66,69,72,75,78,81,84,87,90,93,95-triacontaoxo-62-propan-2-yl-4a,5a,56,57,97,98-hexathia-1a,2,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,61,64,67,70,73,76,79,82,85,88,91,94-triacontazatetracyclo[52.41.7.433,80.02,6]hexahectan-59-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
|
C167H256N48O50S6
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0444827
|
(2R,5S,8S,11S,19S)-19-[(2S)-2-aminohexanamido]-5-(3-carbamimidamidopropyl)-2-[(4-chlorophenyl)methyl]-8-(1H-indol-3-ylmethyl)-3,6,9,17,20,31-hexaoxo-1,4,7,10,16,21-hexaazatricyclo[20.8.1.0^{24,29}]hentriaconta-24(29),25,27-triene-11-carboxamide
Show/Hide
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C52H68ClN13O8
|
2
|
| 1 |
EC50 > 1000 nM
|
|
|
| 2 |
IC50 = 29 nM
|
|
|
|
CP0870609
|
(7S,10R,13S,16S,19R)-10-benzyl-13-(3-carbamimidamidopropyl)-19-carbamoyl-16-(1H-indol-3-ylmethyl)-N-methyl-N,2,8,11,14,17-hexaoxo-21-thia-3,9,12,15,18-pentaazatricyclo[20.4.0.0^{3,7}]hexacosa-1(26),22,24-trien-25-aminium
Show/Hide
|
C41H47N11O8S
|
2
|
| 1 |
EC50 > 1000 nM
|
|
|
| 2 |
IC50 = 380 nM
|
|
|
|
CP0377557
|
(3S,6S,14S,17R,20R,23R,26S)-6-[[(2R)-2-acetamidohexanoyl]amino]-23-benzyl-20-[3-(diaminomethylideneamino)propyl]-3,17-bis(1H-indol-3-ylmethyl)-2,5,8,16,19,22,25-heptaoxo-1,4,9,15,18,21,24-heptazabicyclo[24.3.0]nonacosane-14-carboxamide
Show/Hide
|
C60H79N15O10
|
2
|
| 1 |
EC50 > 1000 nM
|
|
|
| 2 |
IC50 = 580 nM
|
|
|
|
CP0390435
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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C73H100N18O15
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 > 1000 nM
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CP0402862
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-5-carbamimidamido-1-[[(2S)-1-(carboxymethylamino)-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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C75H101N21O16
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 = 56 nM
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CP0407279
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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C75H102N22O15
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 > 1000 nM
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CP0407291
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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C72H100N16O15
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 > 1000 nM
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CP0396380
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2-[(1R,4S,7S,13S,16S,19R,22S,25S,28R,31S,37S,40S,46S)-19,46-dibenzyl-4-[(2S)-butan-2-yl]-16,31-bis(3-carbamimidamidopropyl)-25-[(1R)-1-hydroxyethyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-14,17-dimethyl-3,6,12,15,18,21,24,27,30,33,36,39,45,48-tetradecaoxo-50,51-dithia-2,5,11,14,17,20,23,26,29,32,35,38,44,47-tetradecazatetracyclo[26.20.4.07,11.040,44]dopentacontan-37-yl]acetic acid
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C81H111N23O17S2
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
Ki > 100000 nM
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CP0389090
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(2S)-1-acetyl-N-[(2R)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-(4-fluorophenyl)-1-oxopropan-2-yl]pyrrolidine-2-carboxamide
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C33H41FN6O5
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 = 46.8 nM
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CP0389095
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(2S)-1-acetyl-N-[(2R)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-(4-chlorophenyl)-1-oxopropan-2-yl]pyrrolidine-2-carboxamide
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C33H41ClN6O5
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 > 1000 nM
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CP0392441
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(2S)-1-acetyl-N-[(2R)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-(4-bromophenyl)-1-oxopropan-2-yl]pyrrolidine-2-carboxamide
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C33H41BrN6O5
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 > 1000 nM
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CP0545281
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(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-4,4-dimethyl-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.4.0]octacosa-1(28),24,26-triene-5-carboxamide
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C56H74N14O8S2
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 = 74 nM
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CP0545380
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(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.4.0]octacosa-1(28),24,26-triene-5-carboxamide
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C54H70N14O8S2
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
IC50 = 302 nM
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CP0437026
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(2S)-2-[[(3S,6S,9R,12S,15S,18S)-9-benzyl-3-[[(2S)-2,6-diaminohexanoyl]amino]-12-[3-(diaminomethylideneamino)propyl]-6-(1H-imidazol-5-ylmethyl)-15-methyl-4,7,10,13,16-pentaoxo-1,5,8,11,14,17,21,22-octazabicyclo[18.2.1]tricosa-20(23),21-diene-18-carbonyl]amino]-4-methylsulfanylbutanoic acid
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C43H65N17O9S
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1
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| 1 |
EC50 >= 1910 nM
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CP0269557
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(R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-oxo-2-[4-(2-[1,2,4]triazol-1-ylmethyl-phenyl)-piperazin-1-yl]-ethyl}-amide
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C32H34ClN7O2
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2
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| 1 |
EC50 > 3000 nM
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| 2 |
Ki = 24 nM
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CP0393281
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(R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-oxo-2-[4-(2-[1,2,4]triazol-4-ylmethyl-phenyl)-piperazin-1-yl]-ethyl}-amide
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C32H34ClN7O2
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1
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| 1 |
EC50 > 3000 nM
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CP0390467
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(2S)-2-[[(3S,6S,9R,12S,15S,18S)-3-[[(2S)-2,6-diaminohexanoyl]amino]-12-[3-(diaminomethylideneamino)propyl]-6-(1H-imidazol-5-ylmethyl)-15-(1H-indol-3-ylmethyl)-9-methyl-4,7,10,13,16-pentaoxo-1,5,8,11,14,17,21,22-octazabicyclo[18.2.1]tricosa-20(23),21-diene-18-carbonyl]amino]-4-methylsulfanylbutanoic acid
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C45H66N18O9S
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1
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| 1 |
EC50 > 3000 nM
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CP0410709
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(2S)-2-[[(3S,6S,9S,12S,15S,18S)-9-benzyl-3-[[(2S)-2,6-diaminohexanoyl]amino]-12-[3-(diaminomethylideneamino)propyl]-6-(1H-imidazol-5-ylmethyl)-15-(1H-indol-3-ylmethyl)-4,7,10,13,16-pentaoxo-1,5,8,11,14,17,21,22-octazabicyclo[18.2.1]tricosa-20(23),21-diene-18-carbonyl]amino]-4-methylsulfanylbutanoic acid
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C51H70N18O9S
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1
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| 1 |
EC50 > 3000 nM
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CP0410711
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(2S)-2-[[(3S,6S,9R,12S,15S,18S)-9-[(2R)-butan-2-yl]-3-[[(2S)-2,6-diaminohexanoyl]amino]-12-[3-(diaminomethylideneamino)propyl]-6-(1H-imidazol-5-ylmethyl)-15-(1H-indol-3-ylmethyl)-4,7,10,13,16-pentaoxo-1,5,8,11,14,17,21,22-octazabicyclo[18.2.1]tricosa-20(23),21-diene-18-carbonyl]amino]-4-methylsulfanylbutanoic acid
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C48H72N18O9S
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1
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| 1 |
EC50 > 3000 nM
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CP0436850
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(2S)-2-[[(3S,6S,9R,12S,15S,18S)-9-benzyl-3-[[(2S)-2,6-diaminohexanoyl]amino]-12-[3-(diaminomethylideneamino)propyl]-15-(1H-imidazol-5-ylmethyl)-6-(1H-indol-3-ylmethyl)-4,7,10,13,16-pentaoxo-1,5,8,11,14,17,21,22-octazabicyclo[18.2.1]tricosa-20(23),21-diene-18-carbonyl]amino]-4-methylsulfanylbutanoic acid
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C51H70N18O9S
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1
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| 1 |
EC50 > 3000 nM
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CP0436853
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(2S)-2-[[(3S,6S,9R,12S,15S,18S)-12-(4-aminobutyl)-9-benzyl-3-[[(2S)-2,6-diaminohexanoyl]amino]-6-(1H-imidazol-5-ylmethyl)-15-(1H-indol-3-ylmethyl)-4,7,10,13,16-pentaoxo-1,5,8,11,14,17,21,22-octazabicyclo[18.2.1]tricosa-20(23),21-diene-18-carbonyl]amino]-4-methylsulfanylbutanoic acid
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C51H70N16O9S
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1
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| 1 |
EC50 > 3000 nM
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CP0436854
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(2S)-2-[[(3S,6S,9R,12S,15S,18S)-12-(3-aminopropyl)-9-benzyl-3-[[(2S)-2,6-diaminohexanoyl]amino]-6-(1H-imidazol-5-ylmethyl)-15-(1H-indol-3-ylmethyl)-4,7,10,13,16-pentaoxo-1,5,8,11,14,17,21,22-octazabicyclo[18.2.1]tricosa-20(23),21-diene-18-carbonyl]amino]-4-methylsulfanylbutanoic acid
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C50H68N16O9S
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1
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| 1 |
EC50 > 3000 nM
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CP0456638
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(2S)-2-[[(5S,8S,11R,14S,17S,20S)-5-amino-11-benzyl-14-[3-(diaminomethylideneamino)propyl]-8-(1H-imidazol-5-ylmethyl)-17-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,7,10,13,16,19,23,24-octazabicyclo[20.2.1]pentacosa-22(25),23-diene-20-carbonyl]amino]-4-methylsulfanylbutanoic acid
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C47H62N16O8S
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1
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| 1 |
EC50 > 3000 nM
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CP0507016
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(2S)-2-[[(3S,6S,9R,12S,15S,18S)-9-benzyl-3-[[(2S)-2,6-diaminohexanoyl]amino]-6-(1H-imidazol-5-ylmethyl)-15-(1H-indol-3-ylmethyl)-12-methyl-4,7,10,13,16-pentaoxo-1,5,8,11,14,17,21,22-octazabicyclo[18.2.1]tricosa-20(23),21-diene-18-carbonyl]amino]-4-methylsulfanylbutanoic acid
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C48H63N15O9S
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1
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| 1 |
EC50 > 3000 nM
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CP0870113
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(3R,6S,9S,12R,15S)-12-benzyl-9-(3-carbamimidamidopropyl)-15-(cyclohexylmethyl)-6-(1H-indol-3-ylmethyl)-19-nitro-5,8,11,14,17-pentaoxo-2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17-hexadecahydro-1,4,7,10,13,16-benzothiapentazacyclononadecine-3-carboxamide
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C45H55N11O8S
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2
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| 1 |
EC50 > 4000 nM
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| 2 |
IC50 > 1000 nM
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CP0858764
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(3R,6S,9S,12R)-12-benzyl-9-(3-carbamimidamidopropyl)-6-(1H-indol-3-ylmethyl)-19-nitro-5,8,11,14,17-pentaoxo-1',3',3,4,5,6,7,8,9,10,11,12,13,14,16,17-hexadecahydro-2H-spiro[1,4,7,10,13,16-benzothiapentazacyclononadecine-15,2'-indene]-3-carboxamide
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C46H49N11O8S
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1
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| 1 |
EC50 > 5000 nM
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CP0387782
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Ac-Nle-c[Asp-cis-4-guanidinyl-Pro-DNal(2')-Arg-Trp-Lys]-NH2
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C54H74N16O9
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1
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| 1 |
IC50 = 2.2 nM
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CP0429705
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(9S,12S,15S,18R,21S)-15-[3-(diaminomethylideneamino)propyl]-21-(1H-imidazol-5-ylmethyl)-12-(1H-indol-3-ylmethyl)-18-(naphthalen-2-ylmethyl)-6,11,14,17,20,23-hexaoxo-5,10,13,16,19,22-hexazaspiro[3.19]tricosane-9-carboxamide
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C46H55N13O7
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1
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| 1 |
IC50 = 2.2 nM
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CP0050965
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21-(2-Acetylamino-hexanoylamino)-7-[3-(diaminomethaniminium)-propyl]-10-(1H-indol-3-ylmethyl)-4-naphthalen-2-ylmethyl-2,5,8,11,19,22-hexaoxo-3,6,9,12,18,23-hexaaza-tricyclo[21.7.0.0*24,29*]triaconta-24(29),25,27
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C54H71N15O9
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3
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| 1 |
IC50 = 2.3 nM
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| 2 |
IC50 = 3.3 nM
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| 3 |
Kd = 1.995 nM
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CP0383565
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(11S,14S,17S,20R,23S)-17-[3-(diaminomethylideneamino)propyl]-23-(1H-imidazol-5-ylmethyl)-14-(1H-indol-3-ylmethyl)-20-(naphthalen-2-ylmethyl)-8,13,16,19,22,25-hexaoxo-7,12,15,18,21,24-hexazaspiro[5.19]pentacosane-11-carboxamide
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C48H59N13O7
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1
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| 1 |
IC50 = 4.4 nM
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CP0393262
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(3S)-3-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]acetyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-aminooxy-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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C77H103N21O16
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1
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| 1 |
IC50 = 6 nM
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CP0384356
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(7S,10R,13S,16S,19S)-13-[3-(diaminomethylideneamino)propyl]-16-(1H-indol-3-ylmethyl)-10-(naphthalen-2-ylmethyl)-2,8,11,14,17,28-hexaoxo-3,9,12,15,18,24-hexazatricyclo[27.4.0.03,7]tritriaconta-1(33),29,31-triene-19-carboxamide
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C52H63N11O7
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2
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| 1 |
IC50 = 11 nM
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| 2 |
Kd = 0.1585 nM
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CP0412765
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(2R,5S,8S,11S,25S)-25-amino-5-[3-(diaminomethylideneamino)propyl]-8-(1H-indol-3-ylmethyl)-2-(naphthalen-2-ylmethyl)-3,6,9,17,20,26-hexaoxo-1,4,7,10,16-pentazacyclohexacosane-11-carboxamide
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C46H61N11O7
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2
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| 1 |
IC50 = 12 nM
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| 2 |
Kd = 5.012 nM
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CP0390484
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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C75H101N19O15
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1
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| 1 |
IC50 = 17 nM
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CP0402864
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-phenylpropanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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C72H101N19O15
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1
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| 1 |
IC50 = 18 nM
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CP0850181
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(3R,6S,9S,12S,25aS)-6-(3-carbamimidamidopropyl)-9-(1H-indol-3-ylmethyl)-3-(naphthalen-2-ylmethyl)-1,4,7,10,18,21-hexaoxo-1H,2H,3H,4H,5H,6H,7H,8H,9H,10H,11H,12H,13H,14H,15H,16H,17H,18H,21H,23H,24H,25H,25aH-pyrrolo[2,1-l]1,4,7,10,13,18-hexaazacyclotricosane-12-carboxamide
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C45H55N11O7
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1
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| 1 |
IC50 = 20 nM
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CP0378449
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(4R,7S,10S,13S)-7-[3-(diaminomethylideneamino)propyl]-10-(1H-indol-3-ylmethyl)-4-(naphthalen-2-ylmethyl)-2,5,8,11,19-pentaoxo-3,6,9,12,18,21,24-heptazabicyclo[18.4.0]tetracosa-1(24),20,22-triene-13-carboxamide
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C42H48N12O6
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1
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| 1 |
IC50 = 23 nM
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CP0378387
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(7S,10R,13S,16S,19S)-13-[3-(diaminomethylideneamino)propyl]-16-(1H-indol-3-ylmethyl)-10-(naphthalen-2-ylmethyl)-2,8,11,14,17,25-hexaoxo-3,9,12,15,18,24-hexazatricyclo[24.4.0.03,7]triaconta-1(30),26,28-triene-19-carboxamide
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C49H57N11O7
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1
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| 1 |
IC50 = 32 nM
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CP0378448
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(2R,5S,8S,11S,25S)-25-amino-2-benzyl-5-[3-(diaminomethylideneamino)propyl]-8-(1H-indol-3-ylmethyl)-3,6,9,17,20,26-hexaoxo-1,4,7,10,16-pentazacyclohexacosane-11-carboxamide
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C42H59N11O7
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1
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| 1 |
IC50 = 84 nM
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CP0407275
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(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
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C74H101N17O15
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1
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| 1 |
IC50 = 117 nM
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CP0870610
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(3R,6S,9S,12R,15S)-9-(3-carbamimidamidopropyl)-15-(1H-imidazol-5-ylmethyl)-6-(1H-indol-3-ylmethyl)-12-(naphthalen-2-ylmethyl)-19-nitro-5,8,11,14,17-pentaoxo-2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17-hexadecahydro-1,4,7,10,13,16-benzothiapentazacyclononadecine-3-carboxamide
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C46H49N13O8S
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1
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| 1 |
IC50 = 190 nM
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CP0577292
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(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-21,21-dimethyl-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.4.0]octacosa-1(28),24,26-triene-5-carboxamide
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C56H74N14O8S2
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1
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| 1 |
IC50 = 222 nM
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CP0568756
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(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-4,4,21,21-tetramethyl-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.3.1]octacosa-1(27),24(28),25-triene-5-carboxamide
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C58H78N14O8S2
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1
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| 1 |
IC50 = 450 nM
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CP0543865
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(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-4,4,21,21-tetramethyl-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.4.0]octacosa-1(28),24,26-triene-5-carboxamide
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C58H78N14O8S2
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1
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| 1 |
IC50 = 452 nM
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CP0377556
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(3S,9S,17S,20S,23S,26R,29S)-9-[[(2S)-2-acetamidohexanoyl]amino]-26-benzyl-23-[3-(diaminomethylideneamino)propyl]-20-(1H-indol-3-ylmethyl)-2,8,11,19,22,25,28-heptaoxo-1,7,12,18,21,24,27-heptazatricyclo[27.3.0.03,7]dotriacontane-17-carboxamide
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C54H76N14O10
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1
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| 1 |
IC50 = 590 nM
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CP0485417
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(2S)-2-[[(2R)-2-[[2-[[2-[[2-[acetyl(butyl)amino]acetyl]amino]acetyl]-(4-aminobutyl)amino]acetyl]amino]-3-phenylpropanoyl]amino]-N-[2-[(2-amino-2-oxoethyl)amino]-2-oxoethyl]-5-(diaminomethylideneamino)-N-(1H-indol-3-ylmethyl)pentanamide
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C44H65N13O8
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1
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| 1 |
IC50 = 1995.26 nM
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CP0854294
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2-[(S)-2-((S)-2-Acetylamino-hexanoylamino)-1-oxo-ethylamino]-6-amino-hexanoic acid {1-[{[1-(carbamoylmethyl-carbamoyl)-2-(1H-indol-3-yl)-ethylcarbamoyl]-methyl}-(4-guanidino-butyl)-carbamoyl]-2-phenyl-ethyl}-amide
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C45H67N13O8
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1
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| 1 |
IC50 = 3981.07 nM
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CP0866921
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(S)-2-((R)-2-((S)-4-acetamido-3-oxo-4,5-dihydroazepino[3,4-b]indol-2(1H,3H,10H)-yl)-3-(4-fluorophenyl)propanamido)-N-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-5-guanidinopentanamide
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C40H45FN10O5
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1
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| 1 |
IC50 = 5000 nM
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CP0498439
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(2S)-2-[[2-[[2-[acetyl(butyl)amino]acetyl]amino]acetyl]amino]-6-amino-N-[(2R)-1-[[2-[[2-[(2-amino-2-oxoethyl)amino]-2-oxoethyl]-(1H-indol-3-ylmethyl)amino]-2-oxoethyl]-[3-(diaminomethylideneamino)propyl]amino]-1-oxo-3-phenylpropan-2-yl]hexanamide
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C44H65N13O8
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1
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| 1 |
IC50 = 7943.28 nM
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CP0378445
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(4R,7S,10S,13S)-4-benzyl-7-[3-(diaminomethylideneamino)propyl]-10-(1H-indol-3-ylmethyl)-2,5,8,11,19-pentaoxo-3,6,9,12,18,24-hexazabicyclo[18.3.1]tetracosa-1(23),20(24),21-triene-13-carboxamide
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C39H47N11O6
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1
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| 1 |
IC50 > 10000 nM
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CP0858768
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(3R,6S,9R,12R,15S)-12-benzyl-9-(3-carbamimidamidopropyl)-15-(1H-imidazol-5-ylmethyl)-6-(1H-indol-3-ylmethyl)-19-nitro-5,8,11,14,17-pentaoxo-2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17-hexadecahydro-1,4,7,10,13,16-benzothiapentazacyclononadecine-3-carboxamide
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C42H47N13O8S
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1
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| 1 |
IC50 > 10000 nM
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CP0376306
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Ac-c[Cys-His-D-Phe-Cys]-N-alpha-guanidinylbutyl-D-Trp-NH2
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C39H50N12O6S2
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1
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| 1 |
IC50 > 1000 nM
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CP0381773
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Ac-c[Cys-His-D-Phe-Cys]-N-alpha-guanidinylbutyl-Trp-NH2
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C39H50N12O6S2
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1
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| 1 |
IC50 > 1000 nM
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CP0422316
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Ac-c[Glu-His-D-Nal(2)'-N-alpha-guanidinylbutyl-Orn]-Trp-NH2
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C47H59N13O7
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1
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| 1 |
IC50 > 1000 nM
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CP0439622
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Ac-c[Glu-His-D-Phe-N-alpha-guanidinylbutyl-Orn]-Trp-NH2
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C43H57N13O7
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1
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| 1 |
IC50 > 1000 nM
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CP0453648
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Ac-c[Glu-His-D-Phe-N-alpha-guanidinylbutyl-Dab]-Trp-NH2
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C42H55N13O7
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1
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| 1 |
IC50 > 1000 nM
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CP0378446
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(4R,7S,10S,13S)-7-[3-(diaminomethylideneamino)propyl]-10-(1H-indol-3-ylmethyl)-4-(naphthalen-2-ylmethyl)-2,5,8,11,19-pentaoxo-3,6,9,12,18,24-hexazabicyclo[18.3.1]tetracosa-1(23),20(24),21-triene-13-carboxamide
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C43H49N11O6
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1
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| 1 |
IC50 > 1000 nM
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CP0877953
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(3R,6S,9S,12R,15S)-9-(4-aminobutyl)-12-benzyl-15-(1H-imidazol-5-ylmethyl)-6-(1H-indol-3-ylmethyl)-19-nitro-5,8,11,14,17-pentaoxo-2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17-hexadecahydro-1,4,7,10,13,16-benzothiapentazacyclononadecine-3-carboxamide
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C42H47N11O8S
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1
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| 1 |
IC50 > 1000 nM
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CP0389098
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(2S)-1-acetyl-N-[(2R)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-1-oxo-3-[4-(trifluoromethyl)phenyl]propan-2-yl]pyrrolidine-2-carboxamide
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C34H41F3N6O5
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1
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| 1 |
IC50 > 1000 nM
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CP0411418
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(2S)-1-acetyl-N-[(2R)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]pyrrolidine-2-carboxamide
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C33H42N6O5
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1
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| 1 |
IC50 > 1000 nM
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CP0571200
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(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-21,21-dimethyl-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.2.2]octacosa-1(26),24,27-triene-5-carboxamide
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C56H74N14O8S2
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1
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| 1 |
IC50 > 1000 nM
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CP0576761
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(5R,8S,11S,14R,17S,20R)-20-[[(2S)-2-acetamidohexanoyl]amino]-14-benzyl-11-[3-(diaminomethylideneamino)propyl]-17-(1H-imidazol-5-ylmethyl)-8-(1H-indol-3-ylmethyl)-4,4,21,21-tetramethyl-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.2.2]octacosa-1(26),24,27-triene-5-carboxamide
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C58H78N14O8S2
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1
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| 1 |
IC50 > 1000 nM
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CP0378392
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(2S,5S,8S,11R,14S,23S)-23-amino-8-[3-(diaminomethylideneamino)propyl]-2-(1H-imidazol-5-ylmethyl)-11-(1H-indol-3-ylmethyl)-5-(naphthalen-2-ylmethyl)-3,6,9,12,20,24-hexaoxo-1,4,7,10,13,19-hexazacyclotetracosane-14-carboxamide
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C47H60N14O7
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2
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| 1 |
Kd = 0.02512 nM
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| 2 |
Ki = 5.9 nM
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CP0378500
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Ac-YRMEHdFRWGSPPKD-NH2
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C84H119N25O21S
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1
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| 1 |
Ki = 0.11 nM
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CP0166249
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(4S)-5-[(2S)-1-[(2S)-1-[(2S)-1-[(2S)-1-[2-[(2S)-6-amino-1-[(2S)-2-[N-[(2S)-1-(carboxymethylimino)-1-hydroxy-3-methylbutan-2-yl]-C-hydroxycarbonimidoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]imino-2-hydroxyethyl]imino-1-hydroxy-3-(1H-indol-3-yl)propan-2-yl]imino-5-carbamimidamido-1-hydroxypentan-2-yl]imino-1-hydroxy-3-phenylpropan-2-yl]imino-1-hydroxy-3-(1H-imidazol-5-yl)propan-2-yl]imino-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[[(2S)-1-[(2S)-2-[[(2S)-2-amino-1,4-dihydroxy-4-iminobutylidene]amino]-3-carboxypropanoyl]pyrrolidin-2-yl]-hydroxymethylidene]amino]-1,3-dihydroxypropylidene]amino]-1-hydroxy-3-(4-hydroxyphenyl)propylidene]amino]-1,3-dihydroxypropylidene]amino]-1-hydroxy-4-methylsulfanylbutylidene]amino]-5-hydroxypentanoic acid
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C90H127N25O26S
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1
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| 1 |
Ki = 0.23 nM
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CP0439884
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Ac-YRMEHdFRWG-NH2
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C61H83N19O13S
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1
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| 1 |
Ki = 1.44 nM
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CP0439876
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Ac-YR[CEH(pCl-dF)RWC]-NH2
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C60H78ClN19O13S2
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1
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| 1 |
Ki = 3.12 nM
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CP0439875
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Ac-YR[CEH(d-2alpha-Nal)RWC]-NH2
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C64H81N19O13S2
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1
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| 1 |
Ki = 6.84 nM
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CP0847736
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Ac-YR[CEHdFRWC]SPPKD-NH2
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C83H115N25O21S2
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1
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| 1 |
Ki = 7.91 nM
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CP0378499
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(4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-(2-aminoacetyl)pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-methylsulfanylbutanoyl]amino]-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[(2S)-2-[(2S)-2-[[(2S)-6-amino-1-[[(2S)-1-amino-3-carboxy-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
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C89H127N27O22S
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1
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| 1 |
Ki = 9.23 nM
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CP0434327
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Beta MSH
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C118H174N34O35S
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1
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| 1 |
Ki = 10.64 nM
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CP0485105
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Ac-YR[CEH(pF-dF)RWC]-NH2
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C60H78FN19O13S2
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1
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| 1 |
Ki = 15.87 nM
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CP0964966
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(2S)-1-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-5-amino-5-oxo-2-[[(3S,9S,12S,15S,18S,21R,26R,29S,32S,38S,41S,47S)-9,15,32,38-tetrakis(4-aminobutyl)-21-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-12,18-bis(3-amino-3-oxopropyl)-29,41-dibenzyl-2,8,11,14,17,20,28,31,34,37,40,43,46-tridecaoxo-23,24-dithia-1,7,10,13,16,19,27,30,33,36,39,42,45-tridecazatricyclo[45.3.0.03,7]pentacontane-26-carbonyl]amino]pentanoyl]amino]-3-phenylpropanoyl]amino]hexanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carboxylic acid
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C144H214N38O30S2
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1
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| 1 |
Ki = 30.9 nM
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CP0160526
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(R)-N-((R)-1-(4-(2-(aminomethyl)phenyl)piperazin-1-yl)-3-(4-chlorophenyl)-1-oxopropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
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C30H34ClN5O2
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1
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| 1 |
Ki = 33 nM
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CP0486687
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Ac-R[CEHdFRWC]-NH2
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C51H70N18O11S2
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1
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| 1 |
Ki = 33.76 nM
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CP0961058
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(S)-1-((S)-1-((6S,9S,15S,18S,21R,24S,27S,30S,33S,36S)-1-((S)-1-((S)-1-((2S,5S,8S,11S,14R,17S,20S,23S,26S)-20-((1H-imidazol-5-yl)methyl)-26-amino-5,11-bis(3-amino-3-oxopropyl)-2,8-bis(4-aminobutyl)-23-benzyl-14-(carbamoylthiomethyl)-17-(4-hydroxybenzyl)-28-methyl-4,7,10,13,16,19,22,25-octaoxo-3,6,9,12,15,18,21,24-octaazanonacosane)pyrrolidine-2-carbonyl)pyrrolidin-2-yl)-24-(3-amino-3-oxopropyl)-9,15,30-tris(4-aminobutyl)-6,18,27-tribenzyl-21-(carbamoylthiomethyl)-36-(3-guanidinopropyl)-33-isobutyl-1,4,7,10,13,16,19,22,25,28,31,34-dodecaoxo-2,5,8,11,14,17,20,23,26,29,32,35-dodecaazaheptatriacontane)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxylic acid
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C146H218N40O32S2
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1
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| 1 |
Ki = 37.15 nM
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CP0276967
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Ac-YR[CEHdFRWC]-NH2
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C60H79N19O13S2
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1
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| 1 |
Ki = 55.02 nM
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CP0185382
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Ac-dR[CEHdFRWC]-NH2
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C51H70N18O11S2
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1
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| 1 |
Ki = 56.79 nM
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CP0870297
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2-{3-(2-Amino-ethyl-guanidino)-4-[2-amino-3-(4-fluoro-phenyl)-propionyl]-2-oxo-piperazin-1-yl}-N-methyl-3-naphthalen-2-yl-propionamide
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C30H35FN8O3
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1
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| 1 |
Ki = 76 nM
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CP0486686
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Ac-YK[CEHdFRWC]-NH2
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C60H79N17O13S2
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1
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| 1 |
Ki = 97.97 nM
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CP0433388
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1-{2-[(1S)-(Methylaminoacetamido)-2-methylpropyl]-4-chlorophenyl}-4-[(2R)-methyl-3-(2-methoxy-4-dichlorophenyl)propionyl]piperazine
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C28H38Cl2N4O3
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1
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| 1 |
Ki = 160 nM
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CP0464640
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Ac-YRC(Me)*EHdFRWC(Me)NH2
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C62H85N19O13S2
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1
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| 1 |
Ki = 166.41 nM
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CP0964152
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(2S)-1-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-5-amino-2-[[(3S,9S,12S,15S,18S,21R,26R,29S,32S,38S,41S,47S)-32,38-bis(4-aminobutyl)-21-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-12,18-bis(3-amino-3-oxopropyl)-29,41-dibenzyl-9,15-dimethyl-2,8,11,14,17,20,28,31,34,37,40,43,46-tridecaoxo-23,24-dithia-1,7,10,13,16,19,27,30,33,36,39,42,45-tridecazatricyclo[45.3.0.03,7]pentacontane-26-carbonyl]amino]-5-oxopentanoyl]amino]-3-phenylpropanoyl]amino]hexanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carboxylic acid
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C138H200N36O30S2
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1
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| 1 |
Ki = 169.82 nM
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CP0415759
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1-{2-[(1S)-(Methylaminoacetamido)-2-methylpropyl]-6-fluorophenyl}-4-[(2R)-methyl-3-(2-methoxy-4-chlorophenyl)propionyl]piperazine
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C28H38ClFN4O3
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1
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| 1 |
Ki = 190 nM
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CP0442631
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1-{2-[(1S)-(Methylaminoacetamido)-2-methylpropyl]-4-chlorophenyl}-4-[(2R)-methyl-3-(4-chlorophenyl)propionyl]piperazine
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C27H36Cl2N4O2
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1
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| 1 |
Ki = 200 nM
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CP0442623
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1-{2-[(1S)-((2R)-Aminopropionamido)-2-methylpropyl]-4-chlorophenyl}-4-[(2R)-methyl-3-(2-methoxy-4-dichlorophenyl)propionyl]piperazine
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C28H38Cl2N4O3
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1
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| 1 |
Ki = 220 nM
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CP0944134
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(2S)-1-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-5-amino-2-[[(3S,9S,12S,15S,18S,21R,26R,29S,32S,38S,41S,47S)-32,38-bis(4-aminobutyl)-21-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-12,18-bis(3-amino-3-oxopropyl)-29,41-dibenzyl-9,15-bis(hydroxymethyl)-2,8,11,14,17,20,28,31,34,37,40,43,46-tridecaoxo-23,24-dithia-1,7,10,13,16,19,27,30,33,36,39,42,45-tridecazatricyclo[45.3.0.03,7]pentacontane-26-carbonyl]amino]-5-oxopentanoyl]amino]-3-phenylpropanoyl]amino]hexanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carboxylic acid
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C138H200N36O32S2
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1
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| 1 |
Ki = 223.87 nM
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CP0058986
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1-{2-[(1S)-(methylaminoacetamido)-2-methylpropyl]-4-methylphenyl}-4-[(2R)-methyl-3-(2-fluoro-4-chlorophenyl)propionyl]piperazine
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C28H38ClFN4O2
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1
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| 1 |
Ki = 230 nM
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CP0136197
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1-{2-[(1S)-(aminopropionyl)amino-2-methylpropyl]-4-methylphenyl}-4-[(2R)-methyl-3-(4-chlorophenyl)propionyl]piperazine
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C28H39ClN4O2
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1
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| 1 |
Ki = 270 nM
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CP0961059
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(2S)-1-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-5-amino-2-[[(3S,9S,12S,15S,18S,21R,26R,29S,32S,38S,41S,47S)-32,38-bis(4-aminobutyl)-21-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-12,18-bis(3-amino-3-oxopropyl)-29,41-dibenzyl-9,15-bis(2-methylpropyl)-2,8,11,14,17,20,28,31,34,37,40,43,46-tridecaoxo-23,24-dithia-1,7,10,13,16,19,27,30,33,36,39,42,45-tridecazatricyclo[45.3.0.03,7]pentacontane-26-carbonyl]amino]-5-oxopentanoyl]amino]-3-phenylpropanoyl]amino]hexanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carboxylic acid
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C144H212N36O30S2
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1
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| 1 |
Ki = 275.42 nM
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CP0944118
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(2S)-1-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-5-amino-2-[[(3S,9S,12S,15S,18S,21R,26R,29S,32S,38S,41S,47S)-32,38-bis(4-aminobutyl)-21-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-12,18-bis(3-amino-3-oxopropyl)-29,41-dibenzyl-2,8,11,14,17,20,28,31,34,37,40,43,46-tridecaoxo-9,15-di(propan-2-yl)-23,24-dithia-1,7,10,13,16,19,27,30,33,36,39,42,45-tridecazatricyclo[45.3.0.03,7]pentacontane-26-carbonyl]amino]-5-oxopentanoyl]amino]-3-phenylpropanoyl]amino]hexanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carboxylic acid
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C142H208N36O30S2
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1
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| 1 |
Ki = 281.84 nM
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CP0403125
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Ac-YCit[CEHdFRWC]-NH2
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C60H78N18O14S2
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1
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| 1 |
Ki = 313.48 nM
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CP0376144
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(1S)-[2-{4-[2-methyl-3-(2-methoxy-4-chlorophenyl)propionyl]-1-piperazinyl}-5-(trifluoromethyl)phenyl]-3-methylbutylamine
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C27H35ClF3N3O2
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1
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| 1 |
Ki = 320 nM
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CP0503293
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1-{2-[(1S)-(1-Methyl-3-azetadinylcarbonyl)-amino-2-methylpropyl]-4-chlorophenyl}-4-[(2R)-methyl-3-(4-chlorophenyl)propionyl]piperazine
Show/Hide
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C29H38Cl2N4O2
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1
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| 1 |
Ki = 380 nM
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CP0279198
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1-[(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-thiophen-2-yl-ethylamino)-methyl]-phenyl}-piperazin-1-yl)-ethyl]-3-(2-hydroxy-ethyl)-urea
Show/Hide
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C29H35Cl2N5O3S
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1
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| 1 |
Ki = 390 nM
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CP0485106
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Ac-[CEHdFRWC]-NH2
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C45H58N14O10S2
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1
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| 1 |
Ki = 399.7 nM
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CP0430417
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1-[(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-thiophen-2-yl-ethylamino)-methyl]-phenyl}-piperazin-1-yl)-ethyl]-3-isopropyl-urea
Show/Hide
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C30H37Cl2N5O2S
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1
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| 1 |
Ki = 450 nM
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CP0373687
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1-{4-[(1R)-2-(amino-3-methylbutyl)-6-fluorophenyl]-4-[(2R)-(3-aminopropionylamido)-3-(2,4-dichlorophenyl)propionyl]}-piperazine
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C27H36Cl2FN5O2
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1
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| 1 |
Ki = 450 nM
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CP0386368
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1-{2-[(1S)-(3-Dimethylaminopropionamino)-2-methylpropyl]-4-chlorophenyl}-4-[(2R)-methyl-3-(4-chlorophenyl)propionyl]piperazine
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C29H40Cl2N4O2
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1
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| 1 |
Ki = 450 nM
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CP0081762
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(S)-2-((S)-4-((R)-2-amino-3-(4-fluorophenyl)propanoyl)-3-(2-guanidinoethyl)-2-oxopiperazin-1-yl)-N-methyl-3-(naphthalen-2-yl)propanamide
Show/Hide
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C30H36FN7O3
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1
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| 1 |
Ki = 470 nM
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CP0173276
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1-{2-[(1S)-(3-Dimethylaminopropionamino)-2-methylpropyl]-6-fluorophenyl}-4-[(2R)-methyl-3-(4-chlorophenyl)propionyl]piperazine
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C29H40ClFN4O2
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1
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| 1 |
Ki = 490 nM
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CP0382383
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3-[(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-thiophen-2-yl-ethylamino)-methyl]-phenyl}-piperazin-1-yl)-ethyl]-1,1-dimethyl-urea
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C29H35Cl2N5O2S
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1
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| 1 |
Ki = 560 nM
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CP0050225
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(R)-N-(3-(2,4-dichlorophenyl)-1-oxo-1-(4-(2-((2-(thiophen-2-yl)ethylamino)methyl)phenyl)piperazin-1-yl)propan-2-yl)acetamide
Show/Hide
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C28H32Cl2N4O2S
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1
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| 1 |
Ki = 570 nM
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CP0415761
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1-{2-[(1S)-(Methylaminoacetamido)-2-methylpropyl]-6-fluorophenyl}-4-[(2R)-methyl-3-(4-chlorophenyl)propionyl]piperazine
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C27H36ClFN4O2
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1
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| 1 |
Ki = 570 nM
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CP0485235
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1-Cyclopentyl-3-[(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-(4-{2-[(2-thiophen-2-yl-ethylamino)-methyl]-phenyl}-piperazin-1-yl)-ethyl]-urea
Show/Hide
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C32H39Cl2N5O2S
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1
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| 1 |
Ki = 580 nM
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CP0058988
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1-{2-[(1S)-(3-dimethylaminopropionyl)amino-2-methylpropyl]-4-methylphenyl}-4-[(2R)-methyl-3-(4-chlorophenyl)propionyl]piperazine
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C30H43ClN4O2
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1
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| 1 |
Ki = 590 nM
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CP0234419
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(R)-3-amino-N-(3-(2,4-dichlorophenyl)-1-oxo-1-(4-(2-((2-(thiophen-2-yl)ethylamino)methyl)phenyl)piperazin-1-yl)propan-2-yl)propanamide
Show/Hide
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C29H35Cl2N5O2S
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1
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| 1 |
Ki = 640 nM
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CP0135959
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1-((R)-1-(4-(2-((S)-1-amino-3-methylbutyl)-4-(trifluoromethyl)phenyl)piperazin-1-yl)-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl)pyrrolidin-2-one
Show/Hide
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C29H35Cl2F3N4O2
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1
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| 1 |
Ki = 640 nM
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CP0448705
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3-Amino-N-{(R)-1-(2,4-dichloro-benzyl)-2-[4-(1-{[2-(3-methoxy-phenyl)-acetylamino]-methyl}-cyclohexyl)-piperazin-1-yl]-2-oxo-ethyl}-propionamide
Show/Hide
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C32H43Cl2N5O4
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1
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| 1 |
Ki = 650 nM
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CP0391662
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N-[(2R)-3-(2,4-dichlorophenyl)-1-oxo-1-[4-[2-[(2-thiophen-2-ylethylamino)methyl]phenyl]piperazin-1-yl]propan-2-yl]pyrrolidine-1-carboxamide
Show/Hide
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C31H37Cl2N5O2S
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1
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| 1 |
Ki = 670 nM
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CP0050799
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N-[(1S)-1-[5-chloro-2-[4-[(2R)-3-(4-chlorophenyl)-2-methylpropanoyl]piperazin-1-yl]phenyl]-3-methylbutyl]-3-(dimethylamino)propanamide
Show/Hide
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C30H42Cl2N4O2
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1
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| 1 |
Ki = 710 nM
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CP0486406
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3-Amino-N-((R)-1-(2,4-dichloro-benzyl)-2-oxo-2-{4-[1-(phenylacetylamino-methyl)-cyclohexyl]-piperazin-1-yl}-ethyl)-propionamide
Show/Hide
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C31H41Cl2N5O3
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1
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| 1 |
Ki = 710 nM
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CP0296428
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1-{2-[(1S)-(methylaminopropionyl)amino-2-methylpropyl]-4-methylphenyl}-4-[(2R)-methyl-3-(4-chlorophenyl)propionyl]piperazine
Show/Hide
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C29H41ClN4O2
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1
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| 1 |
Ki = 710 nM
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CP0197235
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1-((R)-1-(4-(2-((S)-1-(2-aminoethylamino)-3-methylbutyl)-6-fluorophenyl)piperazin-1-yl)-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl)pyrrolidin-2-one
Show/Hide
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C30H40Cl2FN5O2
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1
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| 1 |
Ki = 750 nM
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CP0059755
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1-[(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-thiophen-2-yl-ethylamino)-methyl]-phenyl}-piperazin-1-yl)-ethyl]-3-ethyl-urea
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C29H35Cl2N5O2S
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1
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| 1 |
Ki = 790 nM
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CP0392260
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2-fluoroethyl N-[(2R)-3-(2,4-dichlorophenyl)-1-oxo-1-[4-[2-[(2-thiophen-2-ylethylamino)methyl]phenyl]piperazin-1-yl]propan-2-yl]carbamate
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C29H33Cl2FN4O3S
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1
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| 1 |
Ki = 790 nM
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CP0404786
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ethyl N-[(2R)-3-(2,4-dichlorophenyl)-1-oxo-1-[4-[2-[(2-thiophen-2-ylethylamino)methyl]phenyl]piperazin-1-yl]propan-2-yl]carbamate
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C29H34Cl2N4O3S
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1
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| 1 |
Ki = 800 nM
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CP0395344
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3-amino-N-((1S)-1-(2-(4-(3-(2,4-dichlorophenyl)propanoyl)piperazin-1-yl)-5-(trifluoromethyl)phenyl)-2-methylbutyl)propanamide
Show/Hide
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C28H35Cl2F3N4O2
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1
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| 1 |
Ki = 800 nM
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CP0378838
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methyl N-[(2R)-3-(2,4-dichlorophenyl)-1-oxo-1-[4-[2-[(2-thiophen-2-ylethylamino)methyl]phenyl]piperazin-1-yl]propan-2-yl]carbamate
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C28H32Cl2N4O3S
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1
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| 1 |
Ki = 810 nM
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CP0135976
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N-[(1S)-1-[2-[4-[(2R)-3-(2,4-dichlorophenyl)-2-(2-oxopyrrolidin-1-yl)propanoyl]piperazin-1-yl]-5-methylphenyl]-3-methylbutyl]-3-(dimethylamino)propanamide
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C34H47Cl2N5O3
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1
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| 1 |
Ki = 820 nM
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CP0466907
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methyl 4-[[(2R)-3-(2,4-dichlorophenyl)-1-oxo-1-[4-[2-[(2-thiophen-2-ylethylamino)methyl]phenyl]piperazin-1-yl]propan-2-yl]amino]-4-oxobutanoate
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C31H36Cl2N4O4S
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1
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| 1 |
Ki = 830 nM
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CP0442999
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1-Cyclopropyl-3-[(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-(4-{2-[(2-thiophen-2-yl-ethylamino)-methyl]-phenyl}-piperazin-1-yl)-ethyl]-urea
Show/Hide
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C30H35Cl2N5O2S
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1
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| 1 |
Ki = 860 nM
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CP0378852
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4-Amino-N-[(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-(4-{2-[(2-thiophen-2-yl-ethylamino)-methyl]-phenyl}-piperazin-1-yl)-ethyl]-butyramide
Show/Hide
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C30H37Cl2N5O2S
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1
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| 1 |
Ki = 950 nM
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CP0373690
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1-[(R)-2-{4-[(1S)-2-(1-amino-3-methylbutyl)-4-trifluoromethylphenyl]piperazin-1-yl}-1-(2,4-dichlorobenzyl)-2-oxoethyl]-piperazin-2-one
Show/Hide
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C29H36Cl2F3N5O2
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1
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| 1 |
Ki = 950 nM
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CP0399948
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3-Amino-N-[(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[(2-thiophen-2-yl-ethylamino)-methyl]-phenyl}-piperazin-1-yl)-ethyl]-propionamide
Show/Hide
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C29H36ClN5O2S
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2
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| 1 |
Ki = 1000 nM
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| 2 |
Ki = 1400 nM
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CP0372598
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1-tert-Butyl-3-[(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-(4-{2-[(2-thiophen-2-yl-ethylamino)-methyl]-phenyl}-piperazin-1-yl)-ethyl]-urea
Show/Hide
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C31H39Cl2N5O2S
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1
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| 1 |
Ki = 1000 nM
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CP0391936
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3-Amino-N-[(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-(4-{1-[(2-thiophen-2-yl-acetylamino)-methyl]-cyclohexyl}-piperazin-1-yl)-ethyl]-propionamide
Show/Hide
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C29H39Cl2N5O3S
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1
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| 1 |
Ki = 1100 nM
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CP0422196
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(R)-3-amino-N-(3-(2,4-dichlorophenyl)-1-(4-(1-((2-(4-methoxyphenyl)acetamido)methyl)cyclohexyl)piperazin-1-yl)-1-oxopropan-2-yl)propanamide
Show/Hide
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C32H43Cl2N5O4
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1
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| 1 |
Ki = 1100 nM
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CP0373165
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(S)-2-amino-N-(1-(2-(4-(3-(2,4-dichlorophenyl)propanoyl)piperazin-1-yl)-5-(trifluoromethyl)phenyl)-3-methylbutyl)acetamide
Show/Hide
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C27H33Cl2F3N4O2
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1
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| 1 |
Ki = 1200 nM
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CP0453047
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(1S)-(2-{4-[(2R)-methyl-3-(4-chlorophenyl)propionyl]-1-piperazinyl}-5-methylphenyl)-3-methylbutylamine
Show/Hide
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C26H36ClN3O
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1
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| 1 |
Ki = 1300 nM
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CP0041099
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propan-2-yl N-[(2R)-3-(2,4-dichlorophenyl)-1-oxo-1-[4-[2-[(2-thiophen-2-ylethylamino)methyl]phenyl]piperazin-1-yl]propan-2-yl]carbamate
Show/Hide
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C30H36Cl2N4O3S
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1
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| 1 |
Ki = 1300 nM
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CP0430024
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N-[(2R)-3-(4-chlorophenyl)-1-oxo-1-[4-[2-[(2-thiophen-2-ylethylamino)methyl]phenyl]piperazin-1-yl]propan-2-yl]piperidine-3-carboxamide
Show/Hide
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C32H40ClN5O2S
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1
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| 1 |
Ki = 1400 nM
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CP0442321
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4-Amino-N-[(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[(2-thiophen-2-yl-ethylamino)-methyl]-phenyl}-piperazin-1-yl)-ethyl]-butyramide
Show/Hide
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C30H38ClN5O2S
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1
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| 1 |
Ki = 1400 nM
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CP0424914
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N-[(2R)-3-(4-chlorophenyl)-1-[4-[2-(diethylamino)-1-(2-fluorophenyl)ethyl]piperazin-1-yl]-1-oxopropan-2-yl]isoquinoline-3-carboxamide
Show/Hide
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C35H39ClFN5O2
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1
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| 1 |
Ki = 1400 nM
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CP0394376
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(S)-1-(4-(2-(1-amino-3-methylbutyl)-6-fluorophenyl)piperazin-1-yl)-3-(2,4-dichlorophenyl)propan-1-one
Show/Hide
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C24H30Cl2FN3O
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1
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| 1 |
Ki = 1400 nM
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CP0445589
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N-[(2R)-3-(2,4-dichlorophenyl)-1-oxo-1-[4-[2-[(2-thiophen-2-ylethylamino)methyl]phenyl]piperazin-1-yl]propan-2-yl]benzamide
Show/Hide
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C33H34Cl2N4O2S
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1
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| 1 |
Ki = 1600 nM
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CP0403268
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N-[(2R)-3-(4-chlorophenyl)-1-oxo-1-[4-[2-[(2-thiophen-2-ylethylamino)methyl]phenyl]piperazin-1-yl]propan-2-yl]pyridine-3-carboxamide
Show/Hide
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C32H34ClN5O2S
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1
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| 1 |
Ki = 1800 nM
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CP0234420
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(R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid [(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[(2-thiophen-2-yl-ethylamino)-methyl]-phenyl}-piperazin-1-yl)-ethyl]-amide
Show/Hide
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C36H40ClN5O2S
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1
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| 1 |
Ki = 1800 nM
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CP0296277
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1-[(R)-2-{4-[2-((S)-1-amino-3-methylbutyl)-4-trifluoromethylphenyl]-piperazin-1-yl}-1-(4-dichlorobenzyl)-2-oxoethyl]pyrrolidin-2-one
Show/Hide
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C29H36ClF3N4O2
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1
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| 1 |
Ki = 1800 nM
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CP0425108
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-(2R)-[2-aminoacetamido]-3-(4-chlorophenyl)propionyl-1-2-[(2-thienyl)ethylaminomethyl]phenyl piperazine
Show/Hide
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C28H34ClN5O2S
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1
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| 1 |
Ki = 1900 nM
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CP0439032
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N-[(2R)-3-(4-chlorophenyl)-1-[4-[2-(diethylamino)-1-(2-fluorophenyl)ethyl]piperazin-1-yl]-1-oxopropan-2-yl]-1,1-dimethyl-3,4-dihydro-2H-isoquinoline-3-carboxamide
Show/Hide
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C37H47ClFN5O2
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1
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| 1 |
Ki = 1900 nM
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CP0378145
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(R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid [(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[1-(piperidin-3-ylamino)-ethyl]-phenyl}-piperazin-1-yl)-ethyl]-amide
Show/Hide
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C36H45ClN6O2
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1
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| 1 |
Ki = 2000 nM
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CP0437137
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1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-[4-(2-{[2-(2-fluoro-phenyl)-ethylamino]-methyl}-phenyl)-piperazin-1-yl]-2-oxo-ethyl}-amide
Show/Hide
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C38H41ClFN5O2
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1
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| 1 |
Ki = 2300 nM
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CP0391594
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3-Amino-N-[(R)-1-(2,4-dichloro-benzyl)-2-(4-{1-[(2-fluoro-benzylamino)-methyl]-cyclohexyl}-piperazin-1-yl)-2-oxo-ethyl]-propionamide
Show/Hide
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C30H40Cl2FN5O2
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1
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| 1 |
Ki = 2300 nM
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CP0378182
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3-Amino-N-{(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-[4-(1-{[(thiophen-2-ylmethyl)-amino]-methyl}-cyclohexyl)-piperazin-1-yl]-ethyl}-propionamide
Show/Hide
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C28H39Cl2N5O2S
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1
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| 1 |
Ki = 2400 nM
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CP0378345
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N-[(1S)-1-[2-[4-[(2R)-3-(4-chlorophenyl)-2-methylpropanoyl]piperazin-1-yl]-5-methylphenyl]-3-methylbutyl]-3-(dimethylamino)propanamide
Show/Hide
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C31H45ClN4O2
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1
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| 1 |
Ki = 2800 nM
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CP0449030
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3-Amino-N-((R)-1-(2,4-dichloro-benzyl)-2-oxo-2-{4-[1-(phenethylamino-methyl)-cyclohexyl]-piperazin-1-yl}-ethyl)-propionamide
Show/Hide
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C31H43Cl2N5O2
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1
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| 1 |
Ki = 3200 nM
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CP0393003
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N-[(1R)-1-[2-[4-[(2R)-3-(2,4-dichlorophenyl)-2-methylpropanoyl]piperazin-1-yl]-6-methylpyridin-3-yl]-3-methylbutyl]-3-(dimethylamino)propanamide
Show/Hide
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C30H43Cl2N5O2
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1
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| 1 |
Ki = 3300 nM
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CP0432776
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N-[(2R)-3-(4-chlorophenyl)-1-[4-[2-(diethylamino)-1-(2-fluorophenyl)ethyl]piperazin-1-yl]-1-oxopropan-2-yl]-2-(2,3-dihydro-1H-isoindol-1-yl)acetamide
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C35H43ClFN5O2
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1
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| 1 |
Ki = 3400 nM
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CP0377910
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1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid [(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[1-((S)-pyrrolidin-3-ylamino)-ethyl]-phenyl}-piperazin-1-yl)-ethyl]-amide
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C35H43ClN6O2
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1
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| 1 |
Ki = 3600 nM
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CP0466190
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1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-[4-(2-imidazol-1-ylmethyl-phenyl)-piperazin-1-yl]-2-oxo-ethyl}-amide
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C33H35ClN6O2
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1
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| 1 |
Ki = 3600 nM
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CP0081758
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(S)-2-((S)-4-((R)-2-amino-3-(4-fluorophenyl)propanoyl)-3-(2-aminoethyl)-2-oxopiperazin-1-yl)-N-methyl-3-(naphthalen-2-yl)propanamide
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C29H34FN5O3
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1
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| 1 |
Ki = 4122 nM
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CP0424915
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N-[(2R)-3-(4-chlorophenyl)-1-[4-[2-(diethylamino)-1-(2-fluorophenyl)ethyl]piperazin-1-yl]-1-oxopropan-2-yl]-2-(1,2,3,4-tetrahydroisoquinolin-1-yl)acetamide
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C36H45ClFN5O2
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1
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| 1 |
Ki = 4200 nM
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CP0500013
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N-[(2R)-3-(4-chlorophenyl)-1-[4-[2-(diethylamino)-1-(2-fluorophenyl)ethyl]piperazin-1-yl]-1-oxopropan-2-yl]-2-(2-methyl-1,3-dihydroisoindol-1-yl)acetamide
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C36H45ClFN5O2
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1
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| 1 |
Ki = 4600 nM
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CP0496016
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(R)-N-(1-(4-(3-((2-methoxyphenethylamino)methyl)pyridin-2-yl)piperazin-1-yl)-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl)-3-aminopropanamide
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C31H38Cl2N6O3
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1
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| 1 |
Ki = 5000 nM
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CP0424911
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(R)-N-((R)-3-(4-chlorophenyl)-1-(4-(2-(diethylamino)-1-(2-fluorophenyl)ethyl)piperazin-1-yl)-1-oxopropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
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C35H43ClFN5O2
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1
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| 1 |
Ki = 7000 nM
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CP0460887
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(R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-[4-(2-dimethylaminomethyl-phenyl)-piperazin-1-yl]-2-oxo-ethyl}-amide
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C32H38ClN5O2
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1
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| 1 |
Ki = 7000 nM
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CP0423108
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2-{4-[2-Amino-3-(4-fluoro-phenyl)-propionyl]-3-[2-(pyridin-2-ylamino)-ethyl]-piperazin-1-yl}-N-methyl-3-naphthalen-2-yl-propionamide
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C34H37FN6O3
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1
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| 1 |
Ki = 8734 nM
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CP0370229
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(R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-[4-(2-methanesulfonylamino-phenyl)-piperazin-1-yl]-2-oxo-ethyl}-amide
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C30H34ClN5O4S
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1
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| 1 |
Ki = 8800 nM
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CP0424913
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N-[(2R)-3-(4-chlorophenyl)-1-[4-[2-(diethylamino)-1-(2-fluorophenyl)ethyl]piperazin-1-yl]-1-oxopropan-2-yl]-2-(1-methyl-2,3-dihydroisoindol-1-yl)acetamide
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C36H45ClFN5O2
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1
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| 1 |
Ki = 16000 nM
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CP0455107
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2-[4-[2-Amino-3-(4-fluoro-phenyl)-propionyl]-3-(2-dimethylaminoethyl)-2-oxo-piperazin-1-yl]-N-methyl-3-naphthalen-2-yl-propionamide
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C31H38FN5O3
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1
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| 1 |
Ki = 26323 nM
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CP0460800
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2-[(1R,4S,7S,13S,16S,19S,22S,25S,28R,31S,37S,40S,46S)-19,46-dibenzyl-4-[(2S)-butan-2-yl]-16,31-bis(3-carbamimidamidopropyl)-25-[(1R)-1-hydroxyethyl]-22-(1H-imidazol-5-ylmethyl)-13-(1H-indol-3-ylmethyl)-3,6,12,15,18,21,24,27,30,33,36,39,45,48-tetradecaoxo-50,51-dithia-2,5,11,14,17,20,23,26,29,32,35,38,44,47-tetradecazatetracyclo[26.20.4.07,11.040,44]dopentacontan-37-yl]acetic acid
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C79H107N23O17S2
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1
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| 1 |
Ki > 100000 nM
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CP0436210
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Ac-YR[CE(1-Me-H)dFRWC]-NH2
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C61H81N19O13S2
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1
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| 1 |
Ki > 500 nM
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CP0877876
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Ac-YR[CEHFRWC]-NH2
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C60H79N19O13S2
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1
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| 1 |
Ki > 500 nM
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