Brief Information of the Compound and Protein
Compound Name
(S)-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)piperidine-2-carboxamide
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PubChem ID
CID: 11846669
Canonical SMILES
NC(N)=NCCC[C@H]1C[C@H](CN1C(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H]1CCCCN1)OCc1ccc2ccccc2c1
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Compound Formula C34H44N6O3
Compound Structure
Protein Name
Melanocortin receptor 3
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Melanocortin receptor
Uniprot ID
P41968
Gene Name
MC3R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 260 nM
   TI
   LI
   LO
   TS
2
Ki = 156 nM
   TI
   LI
   LO
   TS