Brief Information of the Compound and Protein
Compound Name
1-(3-((2S,4R)-1-((R)-2-amino-3-phenylpropanoyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-2-yl)propyl)guanidine
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PubChem ID
CID: 11845813
SID: 17158598
Canonical SMILES
N[C@H](Cc1ccccc1)C(=O)N1C[C@@H](C[C@@H]1CCCN=C(N)N)OCc1ccc2ccccc2c1
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Compound Formula C28H35N5O2
Compound Structure
Protein Name
Melanocortin receptor 3
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Melanocortin receptor
Uniprot ID
P41968
Gene Name
MC3R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 871 nM
   TI
   LI
   LO
   TS
2
Ki = 1244 nM
   TI
   LI
   LO
   TS