| Compound ID |
Compound Name |
Compound Formula |
|
CP0240582
|
Prx-03140
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|
C19H27N3O3S
|
1
|
| 1 |
EC50 = 17 nM
|
|
|
|
CP0484940
|
US9221790, 3
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|
C25H31ClN4O2
|
1
|
| 1 |
IC50 = 0.039 nM
|
|
|
|
CP0512209
|
US9221790, 7
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|
C19H27ClN6O2
|
1
|
| 1 |
IC50 = 0.067 nM
|
|
|
|
CP0491460
|
US9221790, 10
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|
C24H29ClN4O2
|
1
|
| 1 |
IC50 = 0.076 nM
|
|
|
|
CP0563225
|
US9221790, 6
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|
C21H31ClN6O2
|
1
|
| 1 |
IC50 = 0.103 nM
|
|
|
|
CP0531623
|
US9221790, 13
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|
C21H25ClFN3O2
|
1
|
| 1 |
IC50 = 0.134 nM
|
|
|
|
CP0539429
|
US9221790, 2
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|
C18H26ClN7O2
|
1
|
| 1 |
IC50 = 0.164 nM
|
|
|
|
CP0531621
|
US9221790, 8
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|
C19H27ClN6O2
|
1
|
| 1 |
IC50 = 0.182 nM
|
|
|
|
CP0484078
|
US9221790, 1
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|
C19H27ClN6O2
|
1
|
| 1 |
IC50 = 0.226 nM
|
|
|
|
CP0561399
|
US9221790, 4
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|
C21H30ClN5O2
|
1
|
| 1 |
IC50 = 0.229 nM
|
|
|
|
CP0491459
|
US9221790, 9
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|
C20H25ClN4O2
|
1
|
| 1 |
IC50 = 0.267 nM
|
|
|
|
CP0030226
|
4-Amino-5-chloro-N-{1-[3-(4-fluoro-phenoxy)-propyl]-3-methoxy-piperidin-4-yl}-2-methoxy-benzamide
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|
C23H29ClFN3O4
|
1
|
| 1 |
IC50 = 0.362 nM
|
|
|
|
CP0412057
|
US9221790, 14
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|
C21H26ClN3O3
|
1
|
| 1 |
IC50 = 0.375 nM
|
|
|
|
CP0531622
|
US9221790, 12
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|
C20H27ClN4O2
|
1
|
| 1 |
IC50 = 0.421 nM
|
|
|
|
CP0479873
|
US9221790, 11
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|
C18H24ClN5O2
|
1
|
| 1 |
IC50 = 0.454 nM
|
|
|
|
CP0201648
|
4-[[(3R,4S)-4-[(4-amino-5-chloro-2-methoxybenzoyl)amino]-3-methoxypiperidin-1-yl]methyl]-N,N-dimethylpiperidine-1-carboxamide
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|
C23H36ClN5O4
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0364641
|
4-amino-N-[(3R,4S)-1-[3-(4-benzylpiperidin-1-yl)-3-oxopropyl]-3-methoxypiperidin-4-yl]-5-chloro-2-methoxybenzamide
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|
C29H39ClN4O4
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0573544
|
4-amino-5-chloro-2-methoxy-N-[(3S,4R)-3-methoxy-1-[[1-(2-methylpropanoyl)piperidin-4-yl]methyl]piperidin-4-yl]benzamide
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|
C24H37ClN4O4
|
1
|
| 1 |
IC50 = 68 nM
|
|
|
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CP0127297
|
4-[[(3R,4S)-4-[(4-amino-5-chloro-2-methoxybenzoyl)amino]-3-methoxypiperidin-1-yl]methyl]-N-propan-2-ylpiperidine-1-carboxamide
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|
C24H38ClN5O4
|
1
|
| 1 |
IC50 = 73 nM
|
|
|
|
CP0181087
|
4-amino-5-chloro-2-methoxy-N-[(3R,4S)-3-methoxy-1-[[1-(3-methylbutanoyl)piperidin-4-yl]methyl]piperidin-4-yl]benzamide
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|
C25H39ClN4O4
|
1
|
| 1 |
IC50 = 78 nM
|
|
|
|
CP0413839
|
4-amino-5-chloro-N-[(3R,4S)-1-[[1-(2,2-dimethylpropanoyl)piperidin-4-yl]methyl]-3-methoxypiperidin-4-yl]-2-methoxybenzamide
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|
C25H39ClN4O4
|
1
|
| 1 |
IC50 = 118 nM
|
|
|
|
CP0259049
|
propyl 4-[[(3R,4S)-4-[(4-amino-5-chloro-2-methoxybenzoyl)amino]-3-methoxypiperidin-1-yl]methyl]piperidine-1-carboxylate
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|
C24H37ClN4O5
|
1
|
| 1 |
IC50 = 134 nM
|
|
|
|
CP0568594
|
4-amino-5-chloro-2-methoxy-N-[(3R,4S)-3-methoxy-1-[[1-(2-methylpropanethioyl)piperidin-4-yl]methyl]piperidin-4-yl]benzamide
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|
C24H37ClN4O3S
|
1
|
| 1 |
IC50 = 155 nM
|
|
|
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CP0353451
|
4-amino-N-[(3R,4S)-1-[(1-butanoylpiperidin-4-yl)methyl]-3-methoxypiperidin-4-yl]-5-chloro-2-methoxybenzamide
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|
C24H37ClN4O4
|
1
|
| 1 |
IC50 = 178 nM
|
|
|
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CP0364270
|
methyl 4-[[(3R,4S)-4-[(4-amino-5-chloro-2-methoxybenzoyl)amino]-3-methoxypiperidin-1-yl]methyl]piperidine-1-carboxylate
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|
C22H33ClN4O5
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0059186
|
4-amino-5-chloro-2-methoxy-N-[(3R,4S)-3-methoxy-1-[(1-propanoylpiperidin-4-yl)methyl]piperidin-4-yl]benzamide
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|
C23H35ClN4O4
|
1
|
| 1 |
IC50 = 329 nM
|
|
|
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CP0127296
|
ethyl 4-[[(3R,4S)-4-[(4-amino-5-chloro-2-methoxybenzoyl)amino]-3-methoxypiperidin-1-yl]methyl]piperidine-1-carboxylate
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|
C23H35ClN4O5
|
1
|
| 1 |
IC50 = 377 nM
|
|
|
|
CP0163218
|
4-amino-5-chloro-N-[(3R,4S)-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-yl]-2-methoxybenzamide
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|
C23H29ClFN3O4
|
1
|
| 1 |
IC50 = 483 nM
|
|
|
|
CP0259035
|
4-amino-5-chloro-2-methoxy-N-[(3R,4S)-3-methoxy-1-[(1-propanoylpiperidin-3-yl)methyl]piperidin-4-yl]benzamide
Show/Hide
|
C23H35ClN4O4
|
1
|
| 1 |
IC50 = 493 nM
|
|
|
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CP0353450
|
4-amino-5-chloro-2-methoxy-N-[(3R,4S)-3-methoxy-1-(3-oxo-3-piperidin-1-ylpropyl)piperidin-4-yl]benzamide
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|
C22H33ClN4O4
|
1
|
| 1 |
IC50 = 560 nM
|
|
|
|
CP0201646
|
N-[(3R,4S)-1-[(1-acetylpiperidin-4-yl)methyl]-3-methoxypiperidin-4-yl]-4-amino-5-chloro-2-methoxybenzamide
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|
C22H33ClN4O4
|
1
|
| 1 |
IC50 = 592 nM
|
|
|
|
CP0201647
|
4-amino-5-chloro-2-methoxy-N-[(3R,4S)-3-methoxy-1-[(1-propanethioylpiperidin-4-yl)methyl]piperidin-4-yl]benzamide
Show/Hide
|
C23H35ClN4O3S
|
1
|
| 1 |
IC50 = 593 nM
|
|
|
|
CP0261303
|
4-amino-5-chloro-2-methoxy-N-[(3R,4S)-3-methoxy-1-(3-pyrrol-1-ylpropyl)piperidin-4-yl]benzamide
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|
C21H29ClN4O3
|
1
|
| 1 |
IC50 = 648 nM
|
|
|
|
CP0127187
|
4-amino-5-chloro-2-methoxy-N-[(3R,4S)-3-methoxy-1-[2-(1-propanoylpiperidin-4-yl)ethyl]piperidin-4-yl]benzamide
Show/Hide
|
C24H37ClN4O4
|
1
|
| 1 |
IC50 = 805 nM
|
|
|
|
CP0259034
|
4-amino-5-chloro-2-methoxy-N-[(3R,4S)-3-methoxy-1-(3-oxo-3-pyrrolidin-1-ylpropyl)piperidin-4-yl]benzamide
Show/Hide
|
C21H31ClN4O4
|
1
|
| 1 |
IC50 = 920 nM
|
|
|
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CP0201644
|
4-amino-5-chloro-2-methoxy-N-[(3R,4S)-3-methoxy-1-(3-morpholin-4-yl-3-oxopropyl)piperidin-4-yl]benzamide
Show/Hide
|
C21H31ClN4O5
|
1
|
| 1 |
IC50 = 954 nM
|
|
|
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CP0203842
|
4-amino-5-chloro-2-methoxy-N-[(3R,4S)-3-methoxy-1-[3-(tetrazol-2-yl)propyl]piperidin-4-yl]benzamide
Show/Hide
|
C18H26ClN7O3
|
1
|
| 1 |
IC50 = 1121 nM
|
|
|
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CP0203841
|
4-amino-5-chloro-N-[(3R,4S)-1-(3-imidazol-1-ylpropyl)-3-methoxypiperidin-4-yl]-2-methoxybenzamide
Show/Hide
|
C20H28ClN5O3
|
1
|
| 1 |
IC50 = 1165 nM
|
|
|
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CP0109667
|
4-amino-5-chloro-2-methoxy-N-[(3R,4S)-3-methoxy-1-[3-(1,2,4-triazol-1-yl)propyl]piperidin-4-yl]benzamide
Show/Hide
|
C19H27ClN6O3
|
1
|
| 1 |
IC50 = 1271 nM
|
|
|
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CP0261301
|
4-amino-5-chloro-2-methoxy-N-[(3R,4S)-3-methoxy-1-(2-pyrrol-1-ylethyl)piperidin-4-yl]benzamide
Show/Hide
|
C20H27ClN4O3
|
1
|
| 1 |
IC50 = 5759 nM
|
|
|
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CP0123097
|
3H-GR113808
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|
C19H27N3O4S
|
4
|
| 1 |
Ki = 0.078 nM
|
|
|
| 2 |
Ki = 0.33 nM
|
|
|
| 3 |
Ki = 0.41 nM
|
|
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| 4 |
Ki = 0.53 nM
|
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CP0373139
|
4-Amino-5-chloro-2-methoxy-benzoic acid 2-(4-pyrimidin-2-yl-piperazin-1-yl)-ethyl ester
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|
C18H22ClN5O3
|
4
|
| 1 |
Ki = 2.47 nM
|
|
|
| 2 |
Ki = 3.5 nM
|
|
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| 3 |
Ki = 7.03 nM
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| 4 |
Ki = 8.1 nM
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CP0290551
|
2-Piperidinoethyl 4-amino-5-chloro-2-methoxybenzoate
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|
C15H21ClN2O3
|
4
|
| 1 |
Ki = 3.69 nM
|
|
|
| 2 |
Ki = 7.98 nM
|
|
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| 3 |
Ki = 8.4 nM
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|
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| 4 |
Ki = 10.7 nM
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CP0448968
|
4-Amino-5-chloro-2-methoxy-benzoic acid 2-(4-phenyl-piperazin-1-yl)-ethyl ester
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|
C20H24ClN3O3
|
4
|
| 1 |
Ki = 12.5 nM
|
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| 2 |
Ki = 23 nM
|
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| 3 |
Ki = 32 nM
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| 4 |
Ki = 55 nM
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