Brief Information of the Compound and Protein
Compound Name
4-Amino-5-chloro-N-{1-[3-(4-fluoro-phenoxy)-propyl]-3-methoxy-piperidin-4-yl}-2-methoxy-benzamide
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PubChem ID
CID: 2769
SID: 14882747
Canonical SMILES
COC1CN(CCCOc2ccc(F)cc2)CCC1NC(=O)c1cc(Cl)c(N)cc1OC
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Compound Formula C23H29ClFN3O4
Compound Structure
Protein Name
5-hydroxytryptamine receptor 4
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
Q13639
Gene Name
HTR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7 Chlorocebus aethiops (Green monkey)  1
1
IC50 = 0.362 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 29 nM
2 Ki = 100 nM
3 Ki = 125.89 nM