Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9221790, 11
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 PubChem ID
CID: 54575226
SID: 129979726
Canonical SMILES
COc1cc(N)c(Cl)cc1C(=O)NCC1CCN(Cc2ncc[nH]2)CC1
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Compound Formula C18H24ClN5O2
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 4
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
Q13639
Gene Name
HTR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
IC50 = 0.454 nM
   TI
   LI
   LO
   TS