Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-Amino-5-chloro-2-methoxy-benzoic acid 2-(4-pyrimidin-2-yl-piperazin-1-yl)-ethyl ester
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 PubChem ID
CID: 9800656
SID: 14756564
Canonical SMILES
COc1cc(N)c(Cl)cc1C(=O)OCCN1CCN(CC1)c1ncccn1
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Compound Formula C18H22ClN5O3
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 4
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
Q13639
Gene Name
HTR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000049 C6
 Cell Line Info 
Rattus norvegicus (Rat)  1
1
Ki = 1 nM
   TI
   LI
   LO
   TS
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  4
1
Ki = 2.47 nM
   TI
   LI
   LO
   TS
2
Ki = 3.5 nM
   TI
   LI
   LO
   TS
3
Ki = 7.03 nM
   TI
   LI
   LO
   TS
4
Ki = 8.1 nM
   TI
   LI
   LO
   TS