5-benzyl-N-[(3S)-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]-1,3-oxazole-2-carboxamide

5-benzyl-N-[(3R)-5-methyl-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl]-1,2-oxazole-3-carboxamide

2-benzyl-N-[(3S)-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]tetrazole-5-carboxamide

5-benzyl-N-[(3S)-1-methyl-2-oxo-4,5-dihydro-3H-1-benzazepin-3-yl]-1,2-oxazole-3-carboxamide

methyl N-[(3S)-3-[(5-benzyl-1,2-oxazole-3-carbonyl)amino]-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-7-yl]carbamate

N-[(3S)-7-acetamido-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]-5-benzyl-1,2-oxazole-3-carboxamide

1-benzyl-N-[(3S)-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]imidazole-4-carboxamide

5-benzyl-1-methyl-N-[(3S)-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]pyrazole-3-carboxamide

5-benzyl-N-[(3S)-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]-1,2,4-oxadiazole-3-carboxamide

5-benzyl-N-[(3S)-5-methyl-4-oxo-7-(2-oxo-3H-1,3,4-oxadiazol-5-yl)-2,3-dihydro-1,5-benzoxazepin-3-yl]-1,2-oxazole-3-carboxamide

5-benzyl-N-[(3S)-7-(methanesulfonamido)-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]-1,2-oxazole-3-carboxamide

1-benzyl-N-[(3S)-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]-1,2,4-triazole-3-carboxamide

5-benzyl-N-[(3S)-5-methyl-4-oxo-2,3-dihydro-1H-1,5-benzodiazepin-3-yl]-1,2-oxazole-3-carboxamide

5-benzyl-N-[(3S)-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]-1,3,4-oxadiazole-2-carboxamide

5-benzyl-N-[(3S)-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]-1H-1,2,4-triazole-3-carboxamide

5-benzyl-N-[(3S)-5-methyl-4-oxo-7-(1H-pyrazol-5-yl)-2,3-dihydro-1,5-benzoxazepin-3-yl]-1,2-oxazole-3-carboxamide

1-benzyl-N-[(3S)-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]triazole-4-carboxamide

4-benzyl-N-[(3S)-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]pyridine-2-carboxamide

4-[4-[(3S)-3-(3,5-difluorophenyl)-3,4-dihydropyrazole-2-carbonyl]piperidin-1-yl]pyrimidine-2-carbonitrile

1-[3-(3-fluoro-4-methylphenyl)-3,4-dihydropyrazol-2-yl]-2,2-dimethylpropan-1-one

2,2-dimethyl-1-[(3S)-3-phenyl-3,4-dihydropyrazol-2-yl]propan-1-one

6-[4-[(3S)-3-(3,5-difluorophenyl)-3,4-dihydropyrazole-2-carbonyl]piperidin-1-yl]pyrimidine-4-carbonitrile

2,2-dimethyl-1-[3-(4-methylphenyl)-3,4-dihydropyrazol-2-yl]propan-1-one

1-[3-(3-fluorophenyl)-3,4-dihydropyrazol-2-yl]-2,2-dimethylpropan-1-one

5-benzyl-N-[(3S)-1,5-dimethyl-4-oxo-2,3-dihydro-1,5-benzodiazepin-3-yl]-1,2-oxazole-3-carboxamide

1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[3-(5-pyridin-3-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl]urea

5-benzyl-N-[(3S)-7,9-difluoro-2-oxo-1,3,4,5-tetrahydro-1-benzazepin-3-yl]-1H-1,2,4-triazole-3-carboxamide

5-benzyl-N-[(3S)-7,9-difluoro-1-methyl-2-oxo-4,5-dihydro-3H-1-benzazepin-3-yl]-1H-1,2,4-triazole-3-carboxamide

1-[3-(3,5-difluorophenyl)-3,4-dihydropyrazol-2-yl]-2,2-dimethylpropan-1-one

5-benzyl-N-[(3S)-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]-1,2-oxazole-3-carboxamide

5-[4-[(3S)-3-(3,5-difluorophenyl)-3,4-dihydropyrazole-2-carbonyl]piperidin-1-yl]pyrazine-2-carbonitrile

[1-(1,3-oxazole-4-carbonyl)piperidin-4-yl]-(3-phenyl-3,4-dihydropyrazol-2-yl)methanone

2,2-dimethyl-1-(3-phenyl-3,4-dihydropyrazol-2-yl)propan-1-one

5-benzyl-N-[(3S)-1-methyl-2-oxo-4,5-dihydro-3H-1-benzazepin-3-yl]-1H-1,2,4-triazole-3-carboxamide

[(3S)-3-phenyl-3,4-dihydropyrazol-2-yl]-(1-pyrimidin-2-ylpiperidin-4-yl)methanone

[1-(1,3-oxazole-5-carbonyl)piperidin-4-yl]-[(3S)-3-phenyl-3,4-dihydropyrazol-2-yl]methanone

1-[3-(4-chlorophenyl)-3,4-dihydropyrazol-2-yl]-2,2-dimethylpropan-1-one

cyclohexyl-(3-phenyl-3,4-dihydropyrazol-2-yl)methanone

1-[3-[5-(3-aminophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]phenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea

1-[3-[5-(4-aminophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]phenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea

5-benzyl-N-[(3S)-4-oxo-3,5-dihydro-2H-1,5-benzoxazepin-3-yl]-1,2-oxazole-3-carboxamide

[(3S)-3-phenyl-3,4-dihydropyrazol-2-yl]-(1-pyridin-2-ylpiperidin-4-yl)methanone

[(3S)-3-phenyl-3,4-dihydropyrazol-2-yl]-[1-(1,3-thiazole-4-carbonyl)piperidin-4-yl]methanone

1-[3-[5-(4-ethylsulfonylphenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]phenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea

[(3S)-3-phenyl-3,4-dihydropyrazol-2-yl]-(1-phenylpiperidin-4-yl)methanone

6-[4-[(3S)-3-(3,5-difluorophenyl)-3,4-dihydropyrazole-2-carbonyl]piperidin-1-yl]pyridazine-3-carbonitrile

[(3S)-3-phenyl-3,4-dihydropyrazol-2-yl]-(1-pyrimidin-4-ylpiperidin-4-yl)methanone

1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[3-[5-(3-methylsulfonylphenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]phenyl]urea

[(3S)-3-phenyl-3,4-dihydropyrazol-2-yl]-(1-pyridazin-3-ylpiperidin-4-yl)methanone

1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[3-[5-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridin-3-yl]phenyl]urea

3-[3-[3-[[2-fluoro-5-(trifluoromethyl)phenyl]carbamoylamino]phenyl]-1H-pyrrolo[2,3-b]pyridin-5-yl]benzamide

1-benzyl-N-[(3S)-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]pyrazole-4-carboxamide

5-benzyl-N-[(3S)-2-oxo-1,3,4,5-tetrahydro-1-benzazepin-3-yl]-1H-1,2,4-triazole-3-carboxamide

[(3S)-3-(3,5-difluorophenyl)-3,4-dihydropyrazol-2-yl]-[1-(5-methyl-1,3,4-oxadiazol-2-yl)piperidin-4-yl]methanone

1-[3-(3-chlorophenyl)-3,4-dihydropyrazol-2-yl]-2,2-dimethylpropan-1-one

cyclopentyl-(3-phenyl-3,4-dihydropyrazol-2-yl)methanone

1-[3-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl]-3-[3-(trifluoromethyl)phenyl]urea

1-[2-(3-fluorophenyl)pyrrolidin-1-yl]-2,2-dimethylpropan-1-one

(3-phenyl-3,4-dihydropyrazol-2-yl)-(1-phenylpiperidin-4-yl)methanone

(1-benzoylpiperidin-4-yl)-(3-phenyl-3,4-dihydropyrazol-2-yl)methanone

N-[(3S)-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]-5-pentyl-1,2-oxazole-3-carboxamide

5-benzyl-N-[(3S)-4-oxo-3,5-dihydro-2H-1,5-benzoxazepin-3-yl]-1H-1,2,4-triazole-3-carboxamide

(3-phenyl-3,4-dihydropyrazol-2-yl)-[1-(1H-pyrazole-5-carbonyl)piperidin-4-yl]methanone

[1-(5-methyl-1,3,4-oxadiazol-2-yl)piperidin-4-yl]-[(3S)-3-phenyl-3,4-dihydropyrazol-2-yl]methanone

2,2-dimethyl-1-(3-pyridin-3-yl-3,4-dihydropyrazol-2-yl)propan-1-one

2,2-dimethyl-1-(2-phenylazetidin-1-yl)propan-1-one

1-[4-[(3S)-3-phenyl-3,4-dihydropyrazole-2-carbonyl]piperidin-1-yl]ethanone

2,2-dimethyl-1-[(3S)-5-methyl-3-phenyl-3,4-dihydropyrazol-2-yl]propan-1-one

2-methyl-1-(3-phenyl-3,4-dihydropyrazol-2-yl)propan-1-one

(3-phenyl-3,4-dihydropyrazol-2-yl)-[1-(2H-triazole-4-carbonyl)piperidin-4-yl]methanone

1-(3-methylphenyl)-3-[3-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl]urea

1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[3-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl]urea

2,2,2-trifluoro-1-[4-(3-phenyl-3,4-dihydropyrazole-2-carbonyl)piperidin-1-yl]ethanone

1-[4-(4-aminofuro[2,3-d]pyrimidin-5-yl)phenyl]-3-(5-tert-butyl-1,2-oxazol-3-yl)urea

5-benzyl-N-[(4S)-5-oxo-2,3,4,6-tetrahydro-1,6-benzoxazocin-4-yl]-1,2-oxazole-3-carboxamide

cyclobutyl-(3-phenyl-3,4-dihydropyrazol-2-yl)methanone

3-(4-{4-aminofuro[2,3-d]pyrimidin-5-yl}phenyl)-1-[2-fluoro-5-(trifluoromethyl)phenyl]urea

1-[4-(4-aminofuro[2,3-d]pyrimidin-5-yl)phenyl]-3-(3-ethylphenyl)urea

3-benzyl-N-[(3S)-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]benzamide

5-(cyclohexylmethyl)-N-[(3S)-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]-1,2-oxazole-3-carboxamide

(3-phenyl-3,4-dihydropyrazol-2-yl)-[1-(1H-pyrazole-4-carbonyl)piperidin-4-yl]methanone

(3-phenyl-3,4-dihydropyrazol-2-yl)-[1-(pyridine-2-carbonyl)piperidin-4-yl]methanone

1-[4-(3-phenyl-3,4-dihydropyrazole-2-carbonyl)piperidin-1-yl]propan-1-one

2,2-dimethyl-1-(2-phenylpyrrolidin-1-yl)propan-1-one

(3-phenyl-3,4-dihydropyrazol-2-yl)-[1-(pyridine-3-carbonyl)piperidin-4-yl]methanone

1-(3-nitrophenyl)-3-[3-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl]urea

1-(3-acetylphenyl)-3-[3-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl]urea

(5R)-5-[(7-chloro-1H-indol-3-yl)methyl]-3-methyl-2,4-Imidazolidinedione, 11

5-Phenyl-4,5-dihydro-pyrazole-1-carboxylic acid (3-chloro-phenyl)-amide

2,2-dimethyl-1-(3-pyridin-2-yl-3,4-dihydropyrazol-2-yl)propan-1-one

1-(3-methoxyphenyl)-3-[3-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl]urea

N-[(3S)-4-oxo-3,5-dihydro-2H-1,5-benzoxazepin-3-yl]-3-phenoxybenzamide

2,2-dimethyl-1-[(3S,4S)-4-methyl-3-phenyl-3,4-dihydropyrazol-2-yl]propan-1-one

1-[4-(1-aminoisoquinolin-5-yl)phenyl]-3-(5-tert-butyl-1,2-oxazol-3-yl)urea

3-hydroxy-2,2-dimethyl-1-(3-phenyl-3,4-dihydropyrazol-2-yl)propan-1-one

1-[4-(3-phenyl-3,4-dihydropyrazole-2-carbonyl)piperidin-1-yl]ethanone

1-phenyl-3-(3-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl)urea

1-[4-(1-aminoisoquinolin-5-yl)phenyl]-3-[3-(trifluoromethyl)phenyl]urea

1-[4-(1-aminoisoquinolin-5-yl)phenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea

5-benzyl-N-[(3S)-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]-1,3-thiazole-2-carboxamide

3-(4-{4-aminofuro[2,3-d]pyrimidin-5-yl}phenyl)-1-naphthalen-2-ylurea

2-benzyl-N-[(3S)-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]-1,3-oxazole-4-carboxamide

1-(3-cyclohexyl-3,4-dihydropyrazol-2-yl)-2,2-dimethylpropan-1-one

1-(3-cyclopentyl-3,4-dihydropyrazol-2-yl)-2,2-dimethylpropan-1-one

phenyl-(3-phenyl-3,4-dihydropyrazol-2-yl)methanone

oxan-4-yl-(3-phenyl-3,4-dihydropyrazol-2-yl)methanone

3-(4-{4-aminofuro[2,3-d]pyrimidin-5-yl}phenyl)-1-[3-(trifluoromethyl)phenyl]urea

2,2-dimethyl-1-[3-(1,3-oxazol-4-yl)-3,4-dihydropyrazol-2-yl]propan-1-one

2-benzyl-N-[(3S)-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]-1H-imidazole-5-carboxamide

1-[4-(4-aminofuro[2,3-d]pyrimidin-5-yl)phenyl]-3-[4-fluoro-3-(trifluoromethyl)phenyl]urea

1-[4-(4-aminofuro[2,3-d]pyrimidin-5-yl)phenyl]-3-[4-chloro-3-(trifluoromethyl)phenyl]urea

N-[(3S)-4-oxo-3,5-dihydro-2H-1,5-benzoxazepin-3-yl]-5-pentyl-1H-pyrazole-3-carboxamide

N-[(3S)-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]-5-(2-methylpropyl)-1,2-oxazole-3-carboxamide

1-[4-(1-aminoisoquinolin-5-yl)phenyl]-3-[4-chloro-3-(trifluoromethyl)phenyl]urea

(3-phenyl-3,4-dihydropyrazol-2-yl)-pyridin-4-ylmethanone

(3-phenyl-3,4-dihydropyrazol-2-yl)-pyridin-3-ylmethanone

1-[4-(1-aminoisoquinolin-5-yl)phenyl]-3-[4-fluoro-3-(trifluoromethyl)phenyl]urea

1-[4-(1-aminoisoquinolin-5-yl)phenyl]-3-[3-fluoro-5-(trifluoromethyl)phenyl]urea

cyclohexyl-[4-(3-phenyl-3,4-dihydropyrazole-2-carbonyl)piperidin-1-yl]methanone

5-benzyl-N-[(3S)-5-ethyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]-1,2-oxazole-3-carboxamide

1-[4-(4-aminofuro[2,3-d]pyrimidin-5-yl)phenyl]-3-[3-fluoro-5-(trifluoromethyl)phenyl]urea

1-[3-(1H-imidazol-5-yl)-3,4-dihydropyrazol-2-yl]-2,2-dimethylpropan-1-one

3-(4-{4-aminofuro[2,3-d]pyrimidin-5-yl}phenyl)-1-[3,5-bis(trifluoromethyl)phenyl]urea

1-cyclopentyl-3-[3-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl]urea

1-[4-(4-aminofuro[2,3-d]pyrimidin-5-yl)phenyl]-3-(3-chlorophenyl)urea

(1-methylpiperidin-4-yl)-(3-phenyl-3,4-dihydropyrazol-2-yl)methanone

3-(4-{4-aminofuro[2,3-d]pyrimidin-5-yl}phenyl)-1-[2-chloro-5-(trifluoromethyl)phenyl]urea

1-[4-(1-aminoisoquinolin-5-yl)phenyl]-3-[2-fluoro-3-(trifluoromethyl)phenyl]urea

1-[4-(4-aminofuro[2,3-d]pyrimidin-5-yl)phenyl]-3-[2-fluoro-3-(trifluoromethyl)phenyl]urea

1-[4-(1-aminoisoquinolin-5-yl)phenyl]-3-[2-chloro-5-(trifluoromethyl)phenyl]urea

5-benzyl-N-[(3R)-4-oxo-3,5-dihydro-2H-1,5-benzoxazepin-3-yl]-1,2-oxazole-3-carboxamide

5-benzyl-N-(2-oxo-3,4-dihydro-1H-quinolin-3-yl)-1,2-oxazole-3-carboxamide

5-benzyl-N-[(3S)-5-cyclopropyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]-1,2-oxazole-3-carboxamide

5-benzyl-N-methyl-N-[(3S)-4-oxo-3,5-dihydro-2H-1,5-benzoxazepin-3-yl]-1,2-oxazole-3-carboxamide

5-benzyl-N-[(3R)-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-1,2-oxazole-3-carboxamide

5-benzyl-N-[(3S)-3-methyl-4-oxo-2,5-dihydro-1,5-benzoxazepin-3-yl]-1,2-oxazole-3-carboxamide

5-benzyl-N-[(6S)-5-oxo-1,4-oxazepan-6-yl]-1,2-oxazole-3-carboxamide

N-[(3S)-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]-5-(piperidin-1-ylmethyl)-1,2-oxazole-3-carboxamide

N-[(3S,5aR,9aR)-4-oxo-3,5,5a,6,7,8,9,9a-octahydro-2H-benzo[b][1,4]oxazepin-3-yl]-5-benzyl-1,2-oxazole-3-carboxamide

(3-phenyl-3,4-dihydropyrazol-2-yl)-pyridin-2-ylmethanone

2,2-dimethyl-1-[(3R)-3-phenyl-3,4-dihydropyrazol-2-yl]propan-1-one

2,2-dimethyl-1-(5-phenylpyrazol-1-yl)propan-1-one

3-amino-2,2-dimethyl-1-(3-phenyl-3,4-dihydropyrazol-2-yl)propan-1-one

2,2-dimethyl-1-(2-phenylpiperazin-1-yl)propan-1-one

2,2-dimethyl-1-(2-phenylpiperidin-1-yl)propan-1-one

2,2-dimethyl-1-(4-methyl-2-phenylpiperazin-1-yl)propan-1-one

5-methyl-N-[(3S)-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]-1,2-oxazole-3-carboxamide

2,2-dimethyl-1-(3-phenylmorpholin-4-yl)propan-1-one

1-[3-(4-tert-butylphenyl)-3,4-dihydropyrazol-2-yl]-2,2-dimethylpropan-1-one

2,2-dimethyl-1-[3-(4-methylsulfonylphenyl)-3,4-dihydropyrazol-2-yl]propan-1-one

2,2-dimethyl-1-[3-(oxan-4-yl)-3,4-dihydropyrazol-2-yl]propan-1-one

2,2-dimethyl-1-(2-phenyl-1,3-thiazolidin-3-yl)propan-1-one

2,2-dimethyl-1-[3-(1H-pyrazol-5-yl)-3,4-dihydropyrazol-2-yl]propan-1-one