Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-benzyl-N-[(3S)-4-oxo-3,5-dihydro-2H-1,5-benzoxazepin-3-yl]-1,2-oxazole-3-carboxamide
    Show/Hide
 PubChem ID
CID: 124180534
Canonical SMILES
O=C(N[C@H]1COc2ccccc2NC1=O)c1cc(Cc2ccccc2)on1
    Show/Hide
Compound Formula C20H17N3O4
Compound Structure
Protein Name
 Protein Info 
Receptor-interacting serine/threonine-protein kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RIPK family
Uniprot ID
Q13546
Gene Name
RIPK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000100 U-937
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 16 nM
   TI
   LI
   LO
   TS
2
IC50 = 32 nM
   TI
   LI
   LO
   TS
3
IC50 = 200 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 16 nM
2 IC50 = 32 nM