Brief Information of the Compound and Protein
Compound Name
5-benzyl-N-[(3S)-5-methyl-4-oxo-7-(2-oxo-3H-1,3,4-oxadiazol-5-yl)-2,3-dihydro-1,5-benzoxazepin-3-yl]-1,2-oxazole-3-carboxamide
    Show/Hide
PubChem ID
CID: 118557507
Canonical SMILES
CN1c2cc(ccc2OC[C@H](NC(=O)c2cc(Cc3ccccc3)on2)C1=O)-c1n[nH]c(=O)o1
    Show/Hide
Compound Formula C23H19N5O6
Compound Structure
Protein Name
Receptor-interacting serine/threonine-protein kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RIPK family
Uniprot ID
Q13546
Gene Name
RIPK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000100 U-937 Homo sapiens (Human)  2
1
IC50 = 0.5 nM
   TI
   LI
   LO
   TS
2
IC50 = 3.2 nM
   TI
   LI
   LO
   TS