Brief Information of the Compound and Protein
Compound Name
5-benzyl-N-[(3S)-7,9-difluoro-1-methyl-2-oxo-4,5-dihydro-3H-1-benzazepin-3-yl]-1H-1,2,4-triazole-3-carboxamide
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PubChem ID
CID: 155522577
Canonical SMILES
CN1c2c(F)cc(F)cc2CC[C@H](NC(=O)c2n[nH]c(Cc3ccccc3)n2)C1=O
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Compound Formula C21H19F2N5O2
Compound Structure
Protein Name
Receptor-interacting serine/threonine-protein kinase 1
Protein Classification
Enzyme
>
Kinase
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Protein Kinase
>
TKL protein kinase group
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TKL protein kinase RIPK family
Uniprot ID
Q13546
Gene Name
RIPK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000100 U-937 Homo sapiens (Human)  1
1
IC50 = 6.3 nM
   TI
   LI
   LO
   TS