Brief Information of the Compound and Protein
Compound Name
5-[4-[(3S)-3-(3,5-difluorophenyl)-3,4-dihydropyrazole-2-carbonyl]piperidin-1-yl]pyrazine-2-carbonitrile
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PubChem ID
CID: 134536604
Canonical SMILES
Fc1cc(F)cc(c1)[C@@H]1CC=NN1C(=O)C1CCN(CC1)c1cnc(cn1)C#N
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Compound Formula C20H18F2N6O
Compound Structure
Protein Name
Receptor-interacting serine/threonine-protein kinase 1
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TKL protein kinase group
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TKL protein kinase RIPK family
Uniprot ID
Q13546
Gene Name
RIPK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000100 U-937 Homo sapiens (Human)  1
1
IC50 = 7.9 nM
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