| Compound ID |
Compound Name |
Compound Formula |
|
CP0548642
|
N-[(2R)-2-fluoro-3-hydroxy-3-methylbutyl]-4-(propan-2-ylamino)-6-(pyrazolo[1,5-a]pyrimidin-5-ylamino)pyridine-3-carboxamide
Show/Hide
|
C20H26FN7O2
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0531650
|
3-[[4-(4-fluorophenyl)pyrimidin-2-yl]amino]-4-methyl-N-[3-(4-methylpiperazin-1-yl)phenyl]benzamide
Show/Hide
|
C29H29FN6O
|
1
|
| 1 |
IC50 = 93 nM
|
|
|
|
CP0542983
|
5-[[4-[(4-methylcyclohexyl)amino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyridine-2-carboxamide
Show/Hide
|
C18H21F3N6O
|
1
|
| 1 |
IC50 = 100.85 nM
|
|
|
|
CP0002230
|
4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide
Show/Hide
|
C28H22F3N7O
|
1
|
| 1 |
IC50 = 158 nM
|
|
|
|
CP0576708
|
3-isoquinolin-8-yloxy-4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(4-methylpiperazin-1-yl)phenyl]benzamide
Show/Hide
|
C32H32N6O2
|
1
|
| 1 |
IC50 = 227 nM
|
|
|
|
CP0414399
|
N-[3-butyl-5-(4-methylimidazol-1-yl)phenyl]-4-methyl-3-[(4-phenylpyrimidin-2-yl)amino]benzamide
Show/Hide
|
C32H32N6O
|
1
|
| 1 |
IC50 = 302 nM
|
|
|
|
CP0575007
|
5-[[4-[(4-hydroxycyclohexyl)amino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyridine-2-carboxamide
Show/Hide
|
C17H19F3N6O2
|
1
|
| 1 |
IC50 = 337.35 nM
|
|
|
|
CP0572220
|
3-[3-(4-methylimidazol-1-yl)-5-[[4-methyl-3-[(4-phenylpyrimidin-2-yl)amino]benzoyl]amino]phenyl]propanoic acid
Show/Hide
|
C31H28N6O3
|
1
|
| 1 |
IC50 = 347 nM
|
|
|
|
CP0572107
|
4-[[4-[(4-hydroxycyclohexyl)amino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]benzamide
Show/Hide
|
C18H20F3N5O2
|
1
|
| 1 |
IC50 = 354.5 nM
|
|
|
|
CP0571371
|
4-[[4-[(4-hydroxycyclohexyl)amino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]benzamide
Show/Hide
|
C18H20F3N5O2
|
1
|
| 1 |
IC50 = 432.65 nM
|
|
|
|
CP0489412
|
5-[[4-[(4-aminocyclohexyl)amino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyridine-2-carboxamide
Show/Hide
|
C17H20F3N7O
|
1
|
| 1 |
IC50 = 480.7 nM
|
|
|
|
CP0520828
|
4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-phenylpyrimidin-2-yl)amino]benzamide
Show/Hide
|
C29H23F3N6O
|
1
|
| 1 |
IC50 = 592 nM
|
|
|
|
CP0420314
|
4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-phenoxybenzamide
Show/Hide
|
C25H20F3N3O2
|
1
|
| 1 |
IC50 = 618 nM
|
|
|
|
CP0420309
|
3-[[4-(4-fluorophenyl)pyrimidin-2-yl]amino]-4-methyl-N-[3-(4-methylimidazol-1-yl)-5-morpholin-4-ylphenyl]benzamide
Show/Hide
|
C32H30FN7O2
|
1
|
| 1 |
IC50 = 790 nM
|
|
|
|
CP0550003
|
4-[[4-[(4-aminocyclohexyl)amino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]benzamide
Show/Hide
|
C18H21F3N6O
|
1
|
| 1 |
IC50 = 1472.5 nM
|
|
|
|
CP0420313
|
4-methyl-N-[3-(4-methylimidazol-1-yl)-5-piperazin-1-ylphenyl]-3-[(4-phenylpyrimidin-2-yl)amino]benzamide
Show/Hide
|
C32H32N8O
|
1
|
| 1 |
IC50 = 1490 nM
|
|
|
|
CP0916080
|
6-(4-((1s,4s)-4-aminocyclohexylamino)-5-(trifluoromethyl)pyrimidin-2-ylamino)isoquinolin-1(2H)-one
Show/Hide
|
C20H21F3N6O
|
1
|
| 1 |
IC50 = 1809 nM
|
|
|
|
CP0531736
|
N-[3-[[(3S)-3-aminopiperidin-1-yl]methyl]-5-(4-methylimidazol-1-yl)phenyl]-3-[[4-(4-fluorophenyl)pyrimidin-2-yl]amino]-4-methylbenzamide
Show/Hide
|
C34H35FN8O
|
1
|
| 1 |
IC50 = 1960 nM
|
|
|
|
CP0537717
|
6-ethyl-3-[3-methoxy-4-(4-piperazin-1-ylpiperidin-1-yl)anilino]-5-(oxan-4-ylamino)pyrazine-2-carboxamide
Show/Hide
|
C28H42N8O3
|
1
|
| 1 |
IC50 = 2214.5 nM
|
|
|
|
CP0534212
|
4-methyl-N-[3-(4-methylimidazol-1-yl)-5-[(4-methylpiperazin-1-yl)methyl]phenyl]-3-[(4-phenylpyrimidin-2-yl)amino]benzamide
Show/Hide
|
C34H36N8O
|
1
|
| 1 |
IC50 = 2570 nM
|
|
|
|
CP0542985
|
4-[[4-[(4-aminocyclohexyl)amino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]benzamide
Show/Hide
|
C18H21F3N6O
|
1
|
| 1 |
IC50 = 2708 nM
|
|
|
|
CP0572221
|
(E)-3-[3-(4-methylimidazol-1-yl)-5-[[4-methyl-3-[(4-phenylpyrimidin-2-yl)amino]benzoyl]amino]phenyl]prop-2-enoic acid
Show/Hide
|
C31H26N6O3
|
1
|
| 1 |
IC50 = 2770 nM
|
|
|
|
CP0531738
|
4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(4-methylpiperazin-1-yl)phenyl]-3-[(4-phenylpyrimidin-2-yl)amino]benzamide
Show/Hide
|
C33H34N8O
|
1
|
| 1 |
IC50 = 2880 nM
|
|
|
|
CP0572108
|
CHEMBL5069893
Show/Hide
|
C21H25F3N6O
|
1
|
| 1 |
IC50 = 3049 nM
|
|
|
|
CP0553975
|
3-[[4-(4-fluorophenyl)pyrimidin-2-yl]amino]-4-methyl-N-[3-(3-methyl-1,2-oxazol-5-yl)-5-(4-methylpiperazin-1-yl)phenyl]benzamide
Show/Hide
|
C33H32FN7O2
|
1
|
| 1 |
IC50 = 3100 nM
|
|
|
|
CP0528704
|
5-[[4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyridine-2-carboxamide
Show/Hide
|
C12H11F3N6O
|
1
|
| 1 |
IC50 = 3273 nM
|
|
|
|
CP0574032
|
CHEMBL5082524
Show/Hide
|
C19H23F3N6O
|
1
|
| 1 |
IC50 = 3783 nM
|
|
|
|
CP0489421
|
CHEMBL5088717
Show/Hide
|
C24H27F3N6O
|
1
|
| 1 |
IC50 = 3886.5 nM
|
|
|
|
CP0542989
|
6-[[4-[(4-aminocyclohexyl)amino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]-2-(2-hydroxyethyl)isoquinolin-1-one
Show/Hide
|
C22H25F3N6O2
|
1
|
| 1 |
IC50 = 4118 nM
|
|
|
|
CP0537709
|
5-[[4-(4-hydroxypiperidin-1-yl)-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyridine-2-carboxamide
Show/Hide
|
C16H17F3N6O2
|
1
|
| 1 |
IC50 = 4356.5 nM
|
|
|
|
CP0489420
|
CHEMBL5086431
Show/Hide
|
C19H23F3N6O
|
1
|
| 1 |
IC50 = 4405.5 nM
|
|
|
|
CP0261968
|
6-[[4-[(4-aminocyclohexyl)amino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]-2-methylisoquinolin-1-one
Show/Hide
|
C21H23F3N6O
|
1
|
| 1 |
IC50 = 4524.5 nM
|
|
|
|
CP0571188
|
CHEMBL5086374
Show/Hide
|
C19H21F3N6O
|
1
|
| 1 |
IC50 = 5148.5 nM
|
|
|
|
CP0526736
|
4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(2-sulfamoylethyl)phenyl]-3-[(4-phenylpyrimidin-2-yl)amino]benzamide
Show/Hide
|
C30H29N7O3S
|
1
|
| 1 |
IC50 = 6000 nM
|
|
|
|
CP0550004
|
CHEMBL5082298
Show/Hide
|
C19H23F3N6O2
|
1
|
| 1 |
IC50 = 6841.5 nM
|
|
|
|
CP0261969
|
CHEMBL5092606
Show/Hide
|
C20H25F3N6O
|
1
|
| 1 |
IC50 = 7453 nM
|
|
|
|
CP0537722
|
CHEMBL5087845
Show/Hide
|
C20H23F3N6O
|
1
|
| 1 |
IC50 = 7517 nM
|
|
|
|
CP0575008
|
5-[[4-(4-aminopiperidin-1-yl)-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyridine-2-carboxamide
Show/Hide
|
C16H18F3N7O
|
1
|
| 1 |
IC50 = 9220 nM
|
|
|
|
CP0574794
|
4-[[4-[(4-aminocyclohexyl)amino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]-N-methylbenzamide
Show/Hide
|
C19H23F3N6O
|
1
|
| 1 |
IC50 = 9516.5 nM
|
|
|
|
CP0574324
|
(2S)-1-[[3-[[3-[[4-(4-fluorophenyl)pyrimidin-2-yl]amino]-4-methylbenzoyl]amino]-5-(4-methylimidazol-1-yl)phenyl]methyl]piperidine-2-carboxamide
Show/Hide
|
C35H35FN8O2
|
1
|
| 1 |
IC50 = 9870 nM
|
|
|
|
CP0531653
|
4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(4-methylpiperazin-1-yl)phenyl]benzamide
Show/Hide
|
C23H27N5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0534214
|
3-(3-cyanobenzoyl)-4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(4-methylpiperazin-1-yl)phenyl]benzamide
Show/Hide
|
C31H30N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0557644
|
(2S)-1-[[3-[[3-[[4-(4-fluorophenyl)pyrimidin-2-yl]amino]-4-methylbenzoyl]amino]-5-(4-methylimidazol-1-yl)phenyl]methyl]piperidine-2-carboxylic acid
Show/Hide
|
C35H34FN7O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0557649
|
4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(4-methylpiperazin-1-yl)phenyl]-3-phenoxybenzamide
Show/Hide
|
C29H31N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0571405
|
N-[3-[[(3S)-3-aminopiperidin-1-yl]methyl]-5-(4-methylimidazol-1-yl)phenyl]-4-methyl-3-phenoxybenzamide
Show/Hide
|
C30H33N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0571370
|
N-cyclopropyl-5-[[4-(piperidin-4-ylmethylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyridine-2-carboxamide
Show/Hide
|
C20H24F3N7O
|
1
|
| 1 |
IC50 > 2 nM
|
|
|
|
CP0528703
|
N-phenyl-5-[[4-(piperidin-4-ylmethylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyridine-2-carboxamide
Show/Hide
|
C23H24F3N7O
|
1
|
| 1 |
IC50 > 6 nM
|
|
|
|
CP0489413
|
5-[[4-(piperidin-4-ylmethylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]-N-pyridin-4-ylpyridine-2-carboxamide
Show/Hide
|
C22H23F3N8O
|
1
|
| 1 |
IC50 > 10 nM
|
|
|
|
CP0489422
|
CHEMBL5083603
Show/Hide
|
C17H20F3N7O
|
1
|
| 1 |
IC50 > 10 nM
|
|
|
|
CP0537705
|
5-[[4-(piperidin-4-ylmethylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyridine-2-carboxamide
Show/Hide
|
C17H20F3N7O
|
1
|
| 1 |
IC50 > 10 nM
|
|
|
|
CP0542987
|
[4-(4-methylpiperazin-1-yl)piperidin-1-yl]-[5-[[4-(piperidin-4-ylmethylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyridin-2-yl]methanone
Show/Hide
|
C27H38F3N9O
|
1
|
| 1 |
IC50 > 10 nM
|
|
|
|
CP0550006
|
morpholin-4-yl-[5-[[4-(piperidin-4-ylmethylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyridin-2-yl]methanone
Show/Hide
|
C21H26F3N7O2
|
1
|
| 1 |
IC50 > 10 nM
|
|
|
|
CP0571898
|
N-(4-chlorophenyl)-5-[[4-(piperidin-4-ylmethylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyridine-2-carboxamide
Show/Hide
|
C23H23ClF3N7O
|
1
|
| 1 |
IC50 > 10 nM
|
|
|
|
CP0571899
|
(4-methylpiperazin-1-yl)-[5-[[4-(piperidin-4-ylmethylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyridin-2-yl]methanone
Show/Hide
|
C22H29F3N8O
|
1
|
| 1 |
IC50 > 10 nM
|
|
|
|
CP0571900
|
5-[[4-(oxan-4-ylmethylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyridine-2-carboxamide
Show/Hide
|
C17H19F3N6O2
|
1
|
| 1 |
IC50 > 10 nM
|
|
|
|
CP0054448
|
6,6-dimethyl-8-[1-(oxan-4-ylmethyl)piperidin-4-yl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile
Show/Hide
|
C30H33N3O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0012721
|
[3-[4-[(4-cyclopropylphenyl)methoxy]-3-methoxyphenyl]azetidin-1-yl]-[4-[[(2S)-2,3-dihydroxypropoxy]methyl]pyridin-2-yl]methanone
Show/Hide
|
C30H34N2O6
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0531465
|
US9546153, ex. 367
Show/Hide
|
C20H25F2N7O2
|
1
|
| 1 |
IC50 > 2000 nM
|
|
|
