Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-(4-((1s,4s)-4-aminocyclohexylamino)-5-(trifluoromethyl)pyrimidin-2-ylamino)isoquinolin-1(2H)-one
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Canonical SMILES
N[C@H]1CC[C@@H](Nc2nc(Nc3ccc4c(=O)[nH]ccc4c3)ncc2C(F)(F)F)CC1
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Compound Formula C20H21F3N6O
Compound Structure
Protein Name
 Protein Info 
Mast/stem cell growth factor receptor Kit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P10721
Gene Name
KIT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 1809 nM
   TI
   LI
   LO
   TS