Brief Information of the Compound and Protein
Compound Name
5-[[4-[(4-hydroxycyclohexyl)amino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyridine-2-carboxamide
    Show/Hide
Canonical SMILES
NC(=O)c1ccc(Nc2ncc(c(N[C@H]3CC[C@H](O)CC3)n2)C(F)(F)F)cn1
    Show/Hide
Compound Formula C17H19F3N6O2
Compound Structure
Protein Name
Mast/stem cell growth factor receptor Kit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P10721
Gene Name
KIT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 337.35 nM
   TI
   LI
   LO
   TS