Brief Information of the Compound and Protein
Compound Name
(4-methylpiperazin-1-yl)-[5-[[4-(piperidin-4-ylmethylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyridin-2-yl]methanone
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PubChem ID
CID: 166635395
Canonical SMILES
CN1CCN(CC1)C(=O)c1ccc(Nc2ncc(c(NCC3CCNCC3)n2)C(F)(F)F)cn1
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Compound Formula C22H29F3N8O
Compound Structure
Protein Name
Mast/stem cell growth factor receptor Kit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P10721
Gene Name
KIT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 > 10 nM
   TI
   LI
   LO
   TS