Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-[[4-[(4-aminocyclohexyl)amino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]-2-(2-hydroxyethyl)isoquinolin-1-one
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Canonical SMILES
N[C@H]1CC[C@H](CC1)Nc1nc(Nc2ccc3c(ccn(CCO)c3=O)c2)ncc1C(F)(F)F
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Compound Formula C22H25F3N6O2
Compound Structure
Protein Name
 Protein Info 
Mast/stem cell growth factor receptor Kit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P10721
Gene Name
KIT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 4118 nM
   TI
   LI
   LO
   TS