General Information of the Compound
| Compound ID |
CP0537709
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| Compound Name |
5-[[4-(4-hydroxypiperidin-1-yl)-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyridine-2-carboxamide
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| Structure |
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| Formula |
C16H17F3N6O2
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| Molecular Weight |
382.346
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| Canonical SMILES |
NC(=O)c1ccc(Nc2ncc(c(n2)N2CCC(O)CC2)C(F)(F)F)cn1
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| InChI |
InChI=1S/C16H17F3N6O2/c17-16(18,19)11-8-22-15(23-9-1-2-12(13(20)27)21-7-9)24-14(11)25-5-3-10(26)4-6-25/h1-2,7-8,10,26H,3-6H2,(H2,20,27)(H,22,23,24)
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| InChIKey |
IMUVTTAWPZGUOG-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00888, Mast/stem cell growth factor receptor Kit
Protein ID: PT01204, Receptor-type tyrosine-protein kinase FLT3