Brief Information of the Compound and Protein
Compound Name
5-[[4-(4-hydroxypiperidin-1-yl)-5-(trifluoromethyl)pyrimidin-2-yl]amino]pyridine-2-carboxamide
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PubChem ID
CID: 166634647
Canonical SMILES
NC(=O)c1ccc(Nc2ncc(c(n2)N2CCC(O)CC2)C(F)(F)F)cn1
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Compound Formula C16H17F3N6O2
Compound Structure
Protein Name
Receptor-type tyrosine-protein kinase FLT3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P36888
Gene Name
FLT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 247.1 nM
   TI
   LI
   LO
   TS
2
IC50 = 356.9 nM
   TI
   LI
   LO
   TS