| Compound ID |
Compound Name |
Compound Formula |
|
CP0464888
|
2-[6-(difluoromethoxy)-2-methylpyridin-3-yl]-3,7-dimethyl-5-pentan-3-ylpyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C20H24F2N4O2
|
2
|
| 1 |
EC50 = 0.3 nM
|
|
|
| 2 |
IC50 = 4.5 nM
|
|
|
|
CP0388747
|
2-(4-methoxy-2,6-dimethylphenyl)-3,7-dimethyl-5-pentan-3-ylpyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C22H29N3O2
|
2
|
| 1 |
EC50 = 0.6 nM
|
|
|
| 2 |
IC50 = 2 nM
|
|
|
|
CP0494497
|
N-(2-chloro-4-methoxyphenyl)-3-pentan-3-yl-1,3,8,12-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaen-7-amine
Show/Hide
|
C20H22ClN5O
|
2
|
| 1 |
EC50 = 0.7 nM
|
|
|
| 2 |
IC50 = 3.2 nM
|
|
|
|
CP0504038
|
2-(2-chloro-4-methoxyphenyl)-3-ethyl-7-methyl-5-pentan-3-ylpyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C21H26ClN3O2
|
2
|
| 1 |
EC50 = 0.7 nM
|
|
|
| 2 |
IC50 = 4.6 nM
|
|
|
|
CP0476420
|
2-(2-chloro-4-methoxyphenyl)-3-cyclopropyl-7-methyl-5-pentan-3-ylpyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C22H26ClN3O2
|
2
|
| 1 |
EC50 = 1 nM
|
|
|
| 2 |
IC50 = 5.9 nM
|
|
|
|
CP0399039
|
5-butan-2-yl-2-(2-chloro-4-methoxyphenyl)-3,7-dimethylpyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C19H22ClN3O2
|
2
|
| 1 |
EC50 = 1.1 nM
|
|
|
| 2 |
IC50 = 4.9 nM
|
|
|
|
CP0461416
|
2-(6-methoxy-2-methylpyridin-3-yl)-3,7-dimethyl-5-pentan-3-ylpyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C20H26N4O2
|
2
|
| 1 |
EC50 = 1.1 nM
|
|
|
| 2 |
IC50 = 3.8 nM
|
|
|
|
CP0417024
|
3-ethyl-2-(4-methoxy-2-methylphenyl)-7-methyl-5-pentan-3-ylpyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C22H29N3O2
|
2
|
| 1 |
EC50 = 1.2 nM
|
|
|
| 2 |
IC50 = 9.7 nM
|
|
|
|
CP0497333
|
2-(2-chloro-4-methoxyphenyl)-3,7-dimethyl-5-pentan-3-ylpyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C20H24ClN3O2
|
2
|
| 1 |
EC50 = 1.2 nM
|
|
|
| 2 |
IC50 = 3.8 nM
|
|
|
|
CP0432761
|
2-(4-methoxy-2-methylphenyl)-3,7-dimethyl-5-pentan-3-ylpyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C21H27N3O2
|
2
|
| 1 |
EC50 = 1.7 nM
|
|
|
| 2 |
IC50 = 2.6 nM
|
|
|
|
CP0452151
|
2-(2,4-dimethylphenyl)-3,7-dimethyl-5-pentan-3-ylpyrrolo[1,2-b]pyridazine
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|
C22H28N2
|
2
|
| 1 |
EC50 = 1.8 nM
|
|
|
| 2 |
IC50 = 11.6 nM
|
|
|
|
CP0476419
|
2-(2-ethyl-4,5-dimethoxyphenyl)-3,7-dimethyl-5-pentan-3-ylpyrrolo[1,2-b]pyridazine
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|
C24H32N2O2
|
2
|
| 1 |
EC50 = 1.9 nM
|
|
|
| 2 |
IC50 = 8.9 nM
|
|
|
|
CP0393091
|
5-butan-2-yl-2-(4-methoxy-2-methylphenyl)-3,7-dimethylpyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C20H25N3O2
|
2
|
| 1 |
EC50 = 2.4 nM
|
|
|
| 2 |
IC50 = 5 nM
|
|
|
|
CP0393078
|
3,7-dimethyl-2-(6-methyl-1,3-benzodioxol-5-yl)-5-pentan-3-ylpyrrolo[1,2-b]pyridazine
Show/Hide
|
C22H26N2O2
|
2
|
| 1 |
EC50 = 2.5 nM
|
|
|
| 2 |
IC50 = 18.3 nM
|
|
|
|
CP0393082
|
2-[6-(difluoromethoxy)-4-methylpyridin-3-yl]-3,7-dimethyl-5-pentan-3-ylpyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C20H24F2N4O2
|
2
|
| 1 |
EC50 = 3.2 nM
|
|
|
| 2 |
IC50 = 5.3 nM
|
|
|
|
CP0461414
|
3,7-dimethyl-5-pentan-3-yl-2-(2,4,5-trimethylphenyl)pyrrolo[1,2-b]pyridazine
Show/Hide
|
C23H30N2
|
2
|
| 1 |
EC50 = 3.3 nM
|
|
|
| 2 |
IC50 = 16.6 nM
|
|
|
|
CP0455508
|
N-(2-ethyl-4-methoxyphenyl)-3-pentan-3-yl-1,3,8,12-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaen-7-amine
Show/Hide
|
C22H27N5O
|
2
|
| 1 |
EC50 = 3.5 nM
|
|
|
| 2 |
IC50 = 2.4 nM
|
|
|
|
CP0393088
|
5-butan-2-yl-2-(4-methoxy-2,6-dimethylphenyl)-3,7-dimethylpyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C21H27N3O2
|
2
|
| 1 |
EC50 = 3.5 nM
|
|
|
| 2 |
IC50 = 4.2 nM
|
|
|
|
CP0393090
|
2-(2-chloro-4-methoxyphenyl)-3-(2-hydroxyethyl)-7-methyl-5-pentan-3-ylpyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C21H26ClN3O3
|
2
|
| 1 |
EC50 = 3.5 nM
|
|
|
| 2 |
IC50 = 4.4 nM
|
|
|
|
CP0417025
|
3-cyclopropyl-2-(4-methoxy-2-methylphenyl)-7-methyl-5-pentan-3-ylpyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C23H29N3O2
|
2
|
| 1 |
EC50 = 3.7 nM
|
|
|
| 2 |
IC50 = 5.7 nM
|
|
|
|
CP0458837
|
N-(4-chloro-2-ethylphenyl)-3-pentan-3-yl-1,3,8,12-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaen-7-amine
Show/Hide
|
C21H24ClN5
|
2
|
| 1 |
EC50 = 3.9 nM
|
|
|
| 2 |
IC50 = 4.7 nM
|
|
|
|
CP0472701
|
10-(2-chloro-4-methoxyphenyl)-11-methyl-N-pentan-3-yl-4-oxa-1,8,12-triazatricyclo[7.3.0.03,7]dodeca-2,7,9,11-tetraen-2-amine
Show/Hide
|
C21H25ClN4O2
|
2
|
| 1 |
EC50 = 4 nM
|
|
|
| 2 |
IC50 = 7 nM
|
|
|
|
CP0503328
|
5-N-(2-chloro-4-methoxyphenyl)-6-methyl-7-N,7-N-dipropylpyrazolo[1,5-a]pyrimidine-5,7-diamine
Show/Hide
|
C20H26ClN5O
|
2
|
| 1 |
EC50 = 4 nM
|
|
|
| 2 |
IC50 = 8 nM
|
|
|
|
CP0388740
|
2-(2-chloro-4-methoxyphenyl)-7-methyl-5-pentan-3-yl-3H-pyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C19H22ClN3O2
|
2
|
| 1 |
EC50 = 4 nM
|
|
|
| 2 |
IC50 = 14.3 nM
|
|
|
|
CP0449235
|
3-pentan-3-yl-N-(2,4,6-trimethylphenyl)-1,3,8,12-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaen-7-amine
Show/Hide
|
C22H27N5
|
2
|
| 1 |
EC50 = 4.1 nM
|
|
|
| 2 |
IC50 = 6.1 nM
|
|
|
|
CP0399035
|
3-(2-hydroxyethyl)-2-(4-methoxy-2-methylphenyl)-7-methyl-5-pentan-3-ylpyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C22H29N3O3
|
2
|
| 1 |
EC50 = 4.2 nM
|
|
|
| 2 |
IC50 = 7.8 nM
|
|
|
|
CP0505851
|
5-N-(2-chloro-4-methoxyphenyl)-5-N-(methoxymethyl)-7-N,7-N-dipropylpyrazolo[1,5-a]pyrimidine-5,7-diamine
Show/Hide
|
C21H28ClN5O2
|
2
|
| 1 |
EC50 = 4.4 nM
|
|
|
| 2 |
IC50 = 15 nM
|
|
|
|
CP0437981
|
2-(4-methoxy-2,6-dimethylphenyl)-3,7-dimethyl-5-propan-2-ylpyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C20H25N3O2
|
2
|
| 1 |
EC50 = 4.5 nM
|
|
|
| 2 |
IC50 = 13.1 nM
|
|
|
|
CP0388748
|
2-(4-methoxy-2-methylphenyl)-3,7-dimethyl-5-pentan-3-ylpyrrolo[1,2-b]pyridazine
Show/Hide
|
C22H28N2O
|
2
|
| 1 |
EC50 = 4.9 nM
|
|
|
| 2 |
IC50 = 16.4 nM
|
|
|
|
CP0461412
|
3-(cyclopropylmethyl)-2-(4-methoxy-2-methylphenyl)-7-methyl-5-pentan-3-ylpyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C24H31N3O2
|
2
|
| 1 |
EC50 = 5 nM
|
|
|
| 2 |
IC50 = 3.3 nM
|
|
|
|
CP0399038
|
2-(4-methoxy-2-methylphenyl)-7-methyl-5-pentan-3-yl-3-propan-2-ylpyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C23H31N3O2
|
2
|
| 1 |
EC50 = 5.1 nM
|
|
|
| 2 |
IC50 = 19.2 nM
|
|
|
|
CP0388745
|
2-[6-(dimethylamino)-2-methylpyridin-3-yl]-3,7-dimethyl-5-pentan-3-ylpyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C21H29N5O
|
2
|
| 1 |
EC50 = 5.5 nM
|
|
|
| 2 |
IC50 = 7.8 nM
|
|
|
|
CP0494498
|
7-(4-ethyl-2-methoxyphenoxy)-3-pentan-3-yl-1,3,8,12-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene
Show/Hide
|
C22H26N4O2
|
2
|
| 1 |
EC50 = 5.6 nM
|
|
|
| 2 |
IC50 = 7 nM
|
|
|
|
CP0499546
|
2-(4-ethoxy-2-ethylphenyl)-3,7-dimethyl-5-pentan-3-ylpyrrolo[1,2-b]pyridazine
Show/Hide
|
C24H32N2O
|
2
|
| 1 |
EC50 = 6.9 nM
|
|
|
| 2 |
IC50 = 13.4 nM
|
|
|
|
CP0449231
|
5-N-(2-chloro-4-methoxyphenyl)-6-methyl-7-N-pentan-3-ylpyrazolo[1,5-a]pyrimidine-5,7-diamine
Show/Hide
|
C19H24ClN5O
|
2
|
| 1 |
EC50 = 7.4 nM
|
|
|
| 2 |
IC50 = 7.4 nM
|
|
|
|
CP0393092
|
2-(2-chloro-4-methoxyphenyl)-3,7-dimethyl-5-propan-2-ylpyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C18H20ClN3O2
|
2
|
| 1 |
EC50 = 7.4 nM
|
|
|
| 2 |
IC50 = 8.7 nM
|
|
|
|
CP0499378
|
10-(2-chloro-4-methoxyphenyl)-11-methyl-N-pentan-3-yl-6-oxa-1,8,12-triazatricyclo[7.3.0.03,7]dodeca-2,7,9,11-tetraen-2-amine
Show/Hide
|
C21H25ClN4O2
|
2
|
| 1 |
EC50 = 8 nM
|
|
|
| 2 |
IC50 = 84 nM
|
|
|
|
CP0503321
|
5-N-(2-chloro-4-methoxyphenyl)-6-ethyl-7-N,7-N-dipropylpyrazolo[1,5-a]pyrimidine-5,7-diamine
Show/Hide
|
C21H28ClN5O
|
2
|
| 1 |
EC50 = 8.6 nM
|
|
|
| 2 |
IC50 = 4.2 nM
|
|
|
|
CP0472527
|
5-N-(2-chloro-4-methoxyphenyl)-6-methyl-7-N,7-N-dipropyl-[1,2,4]triazolo[1,5-a]pyrimidine-5,7-diamine
Show/Hide
|
C19H25ClN6O
|
2
|
| 1 |
EC50 = 9 nM
|
|
|
| 2 |
IC50 = 8 nM
|
|
|
|
CP0452152
|
5-(3,7-dimethyl-5-pentan-3-ylpyrrolo[1,2-b]pyridazin-2-yl)-N,N,4-trimethylpyridin-2-amine
Show/Hide
|
C22H30N4
|
2
|
| 1 |
EC50 = 11.5 nM
|
|
|
| 2 |
IC50 = 7.4 nM
|
|
|
|
CP0461413
|
2-(6-methoxy-4-methylpyridin-3-yl)-3,7-dimethyl-5-pentan-3-ylpyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C20H26N4O2
|
2
|
| 1 |
EC50 = 17.2 nM
|
|
|
| 2 |
IC50 = 8.6 nM
|
|
|
|
CP0455505
|
5-N-(2-chloro-4-methoxyphenyl)-5-N-ethyl-7-N,7-N-dipropylpyrazolo[1,5-a]pyrimidine-5,7-diamine
Show/Hide
|
C21H28ClN5O
|
2
|
| 1 |
EC50 = 18.6 nM
|
|
|
| 2 |
IC50 = 31.6 nM
|
|
|
|
CP0425967
|
2-N-(2-chloro-4-methoxyphenyl)-2-N-methyl-4-N,4-N-dipropylpyrazolo[1,5-a][1,3,5]triazine-2,4-diamine
Show/Hide
|
C19H25ClN6O
|
2
|
| 1 |
EC50 = 26 nM
|
|
|
| 2 |
IC50 = 20 nM
|
|
|
|
CP0472526
|
5-N-(2-chloro-4-methoxyphenyl)-5-N-prop-2-enyl-7-N,7-N-dipropylpyrazolo[1,5-a]pyrimidine-5,7-diamine
Show/Hide
|
C22H28ClN5O
|
2
|
| 1 |
EC50 = 28.9 nM
|
|
|
| 2 |
IC50 = 4.4 nM
|
|
|
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CP0498827
|
3-(2-chloro-4-methoxyphenyl)-2,5-dimethyl-N-pentan-3-ylpyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C20H25ClN4O
|
2
|
| 1 |
EC50 = 31 nM
|
|
|
| 2 |
IC50 = 6 nM
|
|
|
|
CP0503324
|
3-pentan-3-yl-7-[(2,4,6-trimethylphenyl)methyl]-1,3,8,12-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene
Show/Hide
|
C23H28N4
|
2
|
| 1 |
EC50 = 32.2 nM
|
|
|
| 2 |
IC50 = 7.1 nM
|
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|
|
CP0388746
|
5-butan-2-yl-2-[6-(dimethylamino)-2-methylpyridin-3-yl]-3,7-dimethylpyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C20H27N5O
|
2
|
| 1 |
EC50 = 36.5 nM
|
|
|
| 2 |
IC50 = 81.2 nM
|
|
|
|
CP0397857
|
10-(2-chloro-4-methoxyphenyl)-11-methyl-N-pentan-3-yl-1,8,12-triazatricyclo[7.3.0.03,7]dodeca-2,7,9,11-tetraen-2-amine
Show/Hide
|
C22H27ClN4O
|
2
|
| 1 |
EC50 = 40 nM
|
|
|
| 2 |
IC50 = 4 nM
|
|
|
|
CP0458838
|
7-N-(2-chloro-4-methoxyphenyl)-6-methyl-5-N,5-N-dipropylimidazo[1,2-a]pyrimidine-5,7-diamine
Show/Hide
|
C20H26ClN5O
|
2
|
| 1 |
EC50 = 46 nM
|
|
|
| 2 |
IC50 = 12 nM
|
|
|
|
CP0499380
|
10-(4-methoxy-2,5-dimethylphenyl)-11-methyl-N-pentan-3-yl-1,8,12-triazatricyclo[7.3.0.03,7]dodeca-2,7,9,11-tetraen-2-amine
Show/Hide
|
C24H32N4O
|
2
|
| 1 |
EC50 = 47 nM
|
|
|
| 2 |
IC50 = 22 nM
|
|
|
|
CP0452153
|
2-(4-methoxy-2-methylphenyl)-7-methyl-3-(2-methylpropyl)-5-pentan-3-ylpyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C24H33N3O2
|
2
|
| 1 |
EC50 = 47.2 nM
|
|
|
| 2 |
IC50 = 111 nM
|
|
|
|
CP0458082
|
5-N-(2-chloro-4-methoxyphenyl)-7-N,7-N-dipropylpyrazolo[1,5-a]pyrimidine-5,7-diamine
Show/Hide
|
C19H24ClN5O
|
2
|
| 1 |
EC50 = 53 nM
|
|
|
| 2 |
IC50 = 61 nM
|
|
|
|
CP0505850
|
5-N-(2-chloro-4-methoxyphenyl)-6-methyl-7-N-pentan-3-yl-[1,2,4]triazolo[1,5-a]pyrimidine-5,7-diamine
Show/Hide
|
C18H23ClN6O
|
2
|
| 1 |
EC50 = 58 nM
|
|
|
| 2 |
IC50 = 16 nM
|
|
|
|
CP0459618
|
10-(2-chloro-4-methoxyphenyl)-11-methyl-N-pentan-3-yl-5-oxa-1,8,12-triazatricyclo[7.3.0.03,7]dodeca-2,7,9,11-tetraen-2-amine
Show/Hide
|
C21H25ClN4O2
|
2
|
| 1 |
EC50 = 66 nM
|
|
|
| 2 |
IC50 = 22 nM
|
|
|
|
CP0450854
|
10-(4-methoxy-2-methylphenyl)-11-methyl-N-pentan-3-yl-5-oxa-1,8,12-triazatricyclo[7.3.0.03,7]dodeca-2,7,9,11-tetraen-2-amine
Show/Hide
|
C22H28N4O2
|
2
|
| 1 |
EC50 = 75 nM
|
|
|
| 2 |
IC50 = 35 nM
|
|
|
|
CP0499061
|
5-N-(2-chloro-4-methoxyphenyl)-5-N,7-N,7-N-tripropylpyrazolo[1,5-a]pyrimidine-5,7-diamine
Show/Hide
|
C22H30ClN5O
|
2
|
| 1 |
EC50 = 75.7 nM
|
|
|
| 2 |
IC50 = 418 nM
|
|
|
|
CP0499060
|
7-N-(2-chloro-4-methoxyphenyl)-7-N-ethyl-5-N,5-N-dipropylimidazo[1,2-a]pyrimidine-5,7-diamine
Show/Hide
|
C21H28ClN5O
|
2
|
| 1 |
EC50 = 76 nM
|
|
|
| 2 |
IC50 = 42 nM
|
|
|
|
CP0450857
|
10-(4-methoxy-2,6-dimethylphenyl)-11-methyl-N-pentan-3-yl-1,8,12-triazatricyclo[7.3.0.03,7]dodeca-2,7,9,11-tetraen-2-amine
Show/Hide
|
C24H32N4O
|
2
|
| 1 |
EC50 = 80 nM
|
|
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| 2 |
IC50 = 9 nM
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CP0449232
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5-N-(2-chloro-4-methoxyphenyl)-7-N,7-N,6-tripropylpyrazolo[1,5-a]pyrimidine-5,7-diamine
Show/Hide
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C22H30ClN5O
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2
|
| 1 |
EC50 = 95 nM
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| 2 |
IC50 = 32 nM
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CP0494496
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5-N-(2-chloro-4-methoxyphenyl)-5-N-methyl-7-N,7-N-dipropylpyrazolo[1,5-a]pyrimidine-5,7-diamine
Show/Hide
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C20H26ClN5O
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2
|
| 1 |
EC50 = 97 nM
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| 2 |
IC50 = 20 nM
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CP0450859
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3-(2-chloro-4-methoxyphenyl)-2,5,6-trimethyl-N-pentan-3-ylpyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
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C21H27ClN4O
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2
|
| 1 |
EC50 = 100 nM
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| 2 |
IC50 = 49 nM
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CP0505840
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5-N-(2-chloro-4-methoxyphenyl)-7-N-pentan-3-ylpyrazolo[1,5-a]pyrimidine-5,7-diamine
Show/Hide
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C18H22ClN5O
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2
|
| 1 |
EC50 = 113 nM
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| 2 |
IC50 = 14 nM
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CP0499379
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10-(4-methoxy-2-methylphenyl)-11-methyl-N-pentan-3-yl-5-thia-1,8,12-triazatricyclo[7.3.0.03,7]dodeca-2,7,9,11-tetraen-2-amine
Show/Hide
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C22H28N4OS
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2
|
| 1 |
EC50 = 150 nM
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|
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| 2 |
IC50 = 37 nM
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CP0452047
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10-(4-methoxy-2-methylphenyl)-11-methyl-N-pentan-3-yl-1,8,12-triazatricyclo[7.3.0.03,7]dodeca-2,7,9,11-tetraen-2-amine
Show/Hide
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C23H30N4O
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2
|
| 1 |
EC50 = 170 nM
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|
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| 2 |
IC50 = 37 nM
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CP0450856
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10-[2-chloro-4-(difluoromethoxy)phenyl]-11-methyl-N-pentan-3-yl-1,8,12-triazatricyclo[7.3.0.03,7]dodeca-2,7,9,11-tetraen-2-amine
Show/Hide
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C22H25ClF2N4O
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2
|
| 1 |
EC50 = 200 nM
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|
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| 2 |
IC50 = 3 nM
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CP0450858
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10-(2,4-dichlorophenyl)-11-methyl-N-pentan-3-yl-1,8,12-triazatricyclo[7.3.0.03,7]dodeca-2,7,9,11-tetraen-2-amine
Show/Hide
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C21H24Cl2N4
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2
|
| 1 |
EC50 = 200 nM
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|
|
| 2 |
IC50 = 37 nM
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CP0494494
|
5-N-(2-chloro-4-methoxyphenyl)-6-propan-2-yl-7-N,7-N-dipropylpyrazolo[1,5-a]pyrimidine-5,7-diamine
Show/Hide
|
C22H30ClN5O
|
2
|
| 1 |
EC50 = 234 nM
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|
|
| 2 |
IC50 = 113 nM
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CP0455507
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5-N-(2-chloro-4-methoxyphenyl)-5-N-methyl-7-N-pentan-3-yl-[1,2,4]triazolo[1,5-a]pyrimidine-5,7-diamine
Show/Hide
|
C18H23ClN6O
|
2
|
| 1 |
EC50 = 367 nM
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|
|
| 2 |
IC50 = 42 nM
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CP0461411
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2-(4-methoxy-2-methylphenyl)-3,7-dimethyl-5-pentan-3-ylimidazo[1,5-b]pyridazine
Show/Hide
|
C21H27N3O
|
2
|
| 1 |
EC50 = 566 nM
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|
|
| 2 |
IC50 = 122 nM
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CP0505466
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10-(4-methoxy-2-methylphenyl)-11-methyl-N-pentan-3-yl-4-oxa-1,8,12-triazatricyclo[7.3.0.03,7]dodeca-2,7,9,11-tetraen-2-amine
Show/Hide
|
C22H28N4O2
|
2
|
| 1 |
EC50 = 640 nM
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|
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| 2 |
IC50 = 31 nM
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|
CP0417016
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2-(4-methoxy-2-methylphenyl)-7-methyl-5-pentan-3-yl-3H-pyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C20H25N3O2
|
2
|
| 1 |
EC50 = 688 nM
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|
|
| 2 |
IC50 = 149 nM
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|
|
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CP0455506
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5-N-(2-chloro-4-methoxyphenyl)-5-N-(2-methylprop-2-enyl)-7-N,7-N-dipropylpyrazolo[1,5-a]pyrimidine-5,7-diamine
Show/Hide
|
C23H30ClN5O
|
2
|
| 1 |
EC50 = 856.1 nM
|
|
|
| 2 |
IC50 = 76.7 nM
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|
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CP0397692
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5-N-(2-chloro-4-methoxyphenyl)-6-methoxy-7-N,7-N-dipropylpyrazolo[1,5-a]pyrimidine-5,7-diamine
Show/Hide
|
C20H26ClN5O2
|
2
|
| 1 |
EC50 = 883 nM
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|
|
| 2 |
IC50 = 13 nM
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|
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|
CP0449234
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5-N-(2-chloro-4-methoxyphenyl)-5-N-methyl-7-N,7-N-dipropyl-[1,2,4]triazolo[1,5-a]pyrimidine-5,7-diamine
Show/Hide
|
C19H25ClN6O
|
2
|
| 1 |
EC50 = 889 nM
|
|
|
| 2 |
IC50 = 33 nM
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|
|
|
CP0505474
|
10-(2,4-dimethylphenyl)-11-methyl-N-pentan-3-yl-1,8,12-triazatricyclo[7.3.0.03,7]dodeca-2,7,9,11-tetraen-2-amine
Show/Hide
|
C23H30N4
|
2
|
| 1 |
EC50 = 920 nM
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|
|
| 2 |
IC50 = 72 nM
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|
|
|
CP0244594
|
(1-Ethyl-propyl)-[3-(4-methoxy-2-methyl-phenyl)-2,5-dimethyl-pyrazolo[1,5-a]pyrimidin-7-yl]-amine
Show/Hide
|
C21H28N4O
|
2
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
Ki = 1 nM
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|
|
|
CP0452051
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10-[2-chloro-4-(trifluoromethoxy)phenyl]-11-methyl-N-pentan-3-yl-1,8,12-triazatricyclo[7.3.0.03,7]dodeca-2,7,9,11-tetraen-2-amine
Show/Hide
|
C22H24ClF3N4O
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0466424
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10-[4-(dimethylamino)-2-methylphenyl]-11-methyl-N-pentan-3-yl-1,8,12-triazatricyclo[7.3.0.03,7]dodeca-2,7,9,11-tetraen-2-amine
Show/Hide
|
C24H33N5
|
1
|
| 1 |
IC50 = 38 nM
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|
|
|
CP0503411
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10-(4-methoxy-2-methylsulfanylphenyl)-11-methyl-N-pentan-3-yl-1,8,12-triazatricyclo[7.3.0.03,7]dodeca-2,7,9,11-tetraen-2-amine
Show/Hide
|
C23H30N4OS
|
1
|
| 1 |
IC50 = 49 nM
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|
|
|
CP0512631
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10-(4-methoxy-2-methylphenyl)-N-pentan-3-yl-11-(trifluoromethyl)-1,8,12-triazatricyclo[7.3.0.03,7]dodeca-2,7,9,11-tetraen-2-amine
Show/Hide
|
C23H27F3N4O
|
1
|
| 1 |
IC50 = 59 nM
|
|
|
|
CP0528196
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7-N-(2-chloro-4-methoxyphenyl)-7-N-methyl-5-N,5-N-dipropylimidazo[1,2-a]pyrimidine-5,7-diamine
Show/Hide
|
C20H26ClN5O
|
1
|
| 1 |
IC50 = 67 nM
|
|
|
|
CP0397859
|
10-(2-chloro-4-ethoxyphenyl)-11-methyl-N-pentan-3-yl-1,8,12-triazatricyclo[7.3.0.03,7]dodeca-2,7,9,11-tetraen-2-amine
Show/Hide
|
C23H29ClN4O
|
1
|
| 1 |
IC50 = 71 nM
|
|
|
|
CP0459615
|
10-(4-methoxy-2-methylphenyl)-11-methyl-N-pentan-3-yl-4-thia-1,8,12-triazatricyclo[7.3.0.03,7]dodeca-2,7,9,11-tetraen-2-amine
Show/Hide
|
C22H28N4OS
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0397856
|
10-(4-fluoro-2-methylphenyl)-11-methyl-N-pentan-3-yl-1,8,12-triazatricyclo[7.3.0.03,7]dodeca-2,7,9,11-tetraen-2-amine
Show/Hide
|
C22H27FN4
|
1
|
| 1 |
IC50 = 93 nM
|
|
|
|
CP0397855
|
11-ethyl-10-(4-methoxy-2-methylphenyl)-N-pentan-3-yl-1,8,12-triazatricyclo[7.3.0.03,7]dodeca-2,7,9,11-tetraen-2-amine
Show/Hide
|
C24H32N4O
|
1
|
| 1 |
IC50 = 97 nM
|
|
|
|
CP0416988
|
2-[6-(dimethylamino)-2-methylpyridin-3-yl]-3,7-dimethyl-5-propan-2-ylpyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C19H25N5O
|
1
|
| 1 |
IC50 = 131 nM
|
|
|
|
CP0521743
|
10-(4-methoxy-2-methylphenyl)-11-methyl-N-pentan-3-yl-1,4,8,12-tetrazatricyclo[7.3.0.03,7]dodeca-2,7,9,11-tetraen-2-amine
Show/Hide
|
C22H29N5O
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0494539
|
5-N-(2-chloro-4-methoxyphenyl)-5-N-(cyclopropylmethyl)-7-N,7-N-dipropylpyrazolo[1,5-a]pyrimidine-5,7-diamine
Show/Hide
|
C23H30ClN5O
|
1
|
| 1 |
IC50 = 213 nM
|
|
|
|
CP0397858
|
10-(4-methoxy-2-methylphenyl)-N-pentan-3-yl-1,8,12-triazatricyclo[7.3.0.03,7]dodeca-2,7,9,11-tetraen-2-amine
Show/Hide
|
C22H28N4O
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0503322
|
5-N-(2-chloro-4-methoxyphenyl)-6-cyclopentyl-7-N,7-N-dipropylpyrazolo[1,5-a]pyrimidine-5,7-diamine
Show/Hide
|
C24H32ClN5O
|
1
|
| 1 |
IC50 = 308 nM
|
|
|
|
CP0461415
|
2-(4-methoxy-2-methylphenyl)-3,8-dimethyl-6-pentan-3-ylimidazo[1,5-a]pyrimidine
Show/Hide
|
C21H27N3O
|
1
|
| 1 |
IC50 = 311 nM
|
|
|
|
CP0449233
|
6-butyl-5-N-(2-chloro-4-methoxyphenyl)-7-N,7-N-dipropylpyrazolo[1,5-a]pyrimidine-5,7-diamine
Show/Hide
|
C23H32ClN5O
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0389023
|
11-cyclobutyl-10-(4-methoxy-2-methylphenyl)-N-pentan-3-yl-1,8,12-triazatricyclo[7.3.0.03,7]dodeca-2,7,9,11-tetraen-2-amine
Show/Hide
|
C26H34N4O
|
1
|
| 1 |
IC50 = 490 nM
|
|
|
|
CP0450855
|
10-(3,4-dimethoxyphenyl)-11-methyl-N-pentan-3-yl-1,8,12-triazatricyclo[7.3.0.03,7]dodeca-2,7,9,11-tetraen-2-amine
Show/Hide
|
C23H30N4O2
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0499225
|
10-(4-methoxy-2-methylphenyl)-11-(methylsulfanylmethyl)-N-pentan-3-yl-1,8,12-triazatricyclo[7.3.0.03,7]dodeca-2,7,9,11-tetraen-2-amine
Show/Hide
|
C24H32N4OS
|
1
|
| 1 |
IC50 = 620 nM
|
|
|
|
CP0503323
|
5-N-(2-chloro-4-methoxyphenyl)-5-N-(2-methoxyethyl)-7-N,7-N-dipropylpyrazolo[1,5-a]pyrimidine-5,7-diamine
Show/Hide
|
C22H30ClN5O2
|
1
|
| 1 |
IC50 = 680 nM
|
|
|
|
CP0452048
|
10-(2,5-dimethylphenyl)-11-methyl-N-pentan-3-yl-1,8,12-triazatricyclo[7.3.0.03,7]dodeca-2,7,9,11-tetraen-2-amine
Show/Hide
|
C23H30N4
|
1
|
| 1 |
IC50 = 820 nM
|
|
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