Brief Information of the Compound and Protein
Compound Name
 Compound Info 
10-[4-(dimethylamino)-2-methylphenyl]-11-methyl-N-pentan-3-yl-1,8,12-triazatricyclo[7.3.0.03,7]dodeca-2,7,9,11-tetraen-2-amine
    Show/Hide
 PubChem ID
CID: 10135080
SID: 15126309
Canonical SMILES
CCC(CC)Nc1c2CCCc2nc2c(c(C)nn12)-c1ccc(cc1C)N(C)C
    Show/Hide
Compound Formula C24H33N5
Compound Structure
Protein Name
 Protein Info 
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
>
Corticotropin releasing factor receptor
>
Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 38 nM
   TI
   LI
   LO
   TS