Brief Information of the Compound and Protein
Compound Name
 Compound Info 
10-(4-methoxy-2-methylphenyl)-11-methyl-N-pentan-3-yl-5-thia-1,8,12-triazatricyclo[7.3.0.03,7]dodeca-2,7,9,11-tetraen-2-amine
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 PubChem ID
CID: 10178898
SID: 15174356
Canonical SMILES
CCC(CC)Nc1c2CSCc2nc2c(c(C)nn12)-c1ccc(OC)cc1C
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Compound Formula C22H28N4OS
Compound Structure
Protein Name
 Protein Info 
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
>
Corticotropin releasing factor receptor
>
Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 150 nM
   TI
   LI
   LO
   TS
2
IC50 = 37 nM
   TI
   LI
   LO
   TS