Brief Information of the Compound and Protein
Compound Name
5-N-(2-chloro-4-methoxyphenyl)-7-N-pentan-3-ylpyrazolo[1,5-a]pyrimidine-5,7-diamine
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PubChem ID
CID: 56677028
Canonical SMILES
CCC(CC)Nc1cc(Nc2ccc(OC)cc2Cl)nc2ccnn12
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Compound Formula C18H22ClN5O
Compound Structure
Protein Name
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
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Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Corticotropin releasing factor receptor
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Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
EC50 = 113 nM
   TI
   LI
   LO
   TS
2
IC50 = 14 nM
   TI
   LI
   LO
   TS