Brief Information of the Compound and Protein
Compound Name
2-(2,4-dimethylphenyl)-3,7-dimethyl-5-pentan-3-ylpyrrolo[1,2-b]pyridazine
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PubChem ID
CID: 24758072
SID: 49661916
Canonical SMILES
CCC(CC)c1cc(C)n2nc(c(C)cc12)-c1ccc(C)cc1C
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Compound Formula C22H28N2
Compound Structure
Protein Name
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Corticotropin releasing factor receptor
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Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
EC50 = 1.8 nM
   TI
   LI
   LO
   TS
2
IC50 = 11.6 nM
   TI
   LI
   LO
   TS