Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-butan-2-yl-2-[6-(dimethylamino)-2-methylpyridin-3-yl]-3,7-dimethylpyrrolo[2,1-f][1,2,4]triazin-4-one
    Show/Hide
 PubChem ID
CID: 57400683
Canonical SMILES
CCC(C)c1cc(C)n2nc(-c3ccc(nc3C)N(C)C)n(C)c(=O)c12
    Show/Hide
Compound Formula C20H27N5O
Compound Structure
Protein Name
 Protein Info 
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
>
Corticotropin releasing factor receptor
>
Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 36.5 nM
   TI
   LI
   LO
   TS
2
IC50 = 81.2 nM
   TI
   LI
   LO
   TS