Brief Information of the Compound and Protein
Compound Name
5-N-(2-chloro-4-methoxyphenyl)-5-N-ethyl-7-N,7-N-dipropylpyrazolo[1,5-a]pyrimidine-5,7-diamine
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PubChem ID
CID: 56680359
Canonical SMILES
CCCN(CCC)c1cc(nc2ccnn12)N(CC)c1ccc(OC)cc1Cl
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Compound Formula C21H28ClN5O
Compound Structure
Protein Name
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Corticotropin releasing factor receptor
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Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
EC50 = 18.6 nM
   TI
   LI
   LO
   TS
2
IC50 = 31.6 nM
   TI
   LI
   LO
   TS