| Compound ID |
Compound Name |
Compound Formula |
|
CP0049196
|
2-benzyl-6,7,8,9-tetrahydro-5H-pyrimido[5,4-d]azepine
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|
C15H17N3
|
2
|
| 1 |
EC50 = 4.5 nM
|
|
|
| 2 |
EC50 = 190 nM
|
|
|
|
CP0394689
|
10-[3-(2-Fluoro-phenoxy)-azetidin-1-yl]-6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene
Show/Hide
|
C19H20FN5O
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0426449
|
10-Azetidin-1-yl-6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene
Show/Hide
|
C13H17N5
|
1
|
| 1 |
EC50 = 5.4 nM
|
|
|
|
CP0378951
|
7-(2-fluorophenylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine
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|
C16H16FNO2S
|
1
|
| 1 |
EC50 = 7 nM
|
|
|
|
CP0394687
|
5-[1-(6,7,8,9-Tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]inden-10-yl)-azetidin-3-yloxy]-1,3-dihydro-indol-2-one
Show/Hide
|
C21H22N6O2
|
1
|
| 1 |
EC50 = 8.4 nM
|
|
|
|
CP0231349
|
7-(phenylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine
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|
C16H17NO2S
|
1
|
| 1 |
EC50 = 9 nM
|
|
|
|
CP0423183
|
7-(3-fluorophenylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine
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|
C16H16FNO2S
|
1
|
| 1 |
EC50 = 9 nM
|
|
|
|
CP0433760
|
2-(2-chlorophenethoxy)-6-(piperazin-1-yl)pyrazine
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|
C16H19ClN4O
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0129858
|
(9S)-2-benzyl-N,9-dimethyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine
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|
C17H22N4
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0156756
|
(R)-6-(2-methylpiperazin-1-yl)-2-(2-(2-(trifluoromethyl)phenoxy)ethyl)pyridazin-3(2H)-one
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|
C18H21F3N4O2
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0344661
|
7-(3-(3-chlorophenoxy)azetidin-1-ylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Show/Hide
|
C19H21ClN2O3S
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0291086
|
(R)-7-(3-(2-chlorophenoxy)pyrrolidin-1-ylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine
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|
C20H23ClN2O3S
|
1
|
| 1 |
EC50 = 14 nM
|
|
|
|
CP0128654
|
2-[difluoro(phenyl)methyl]-N-methyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine
Show/Hide
|
C16H18F2N4
|
1
|
| 1 |
EC50 = 16 nM
|
|
|
|
CP0470834
|
10-(3-Phenoxy-azetidin-1-yl)-6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraazacyclohepta[f]indene
Show/Hide
|
C19H21N5O
|
1
|
| 1 |
EC50 = 18 nM
|
|
|
|
CP0499026
|
10-[3-(4-Fluoro-phenoxy)-azetidin-1-yl]-6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene
Show/Hide
|
C19H20FN5O
|
1
|
| 1 |
EC50 = 23 nM
|
|
|
|
CP0433759
|
(R)-2-(2-(2-chlorophenoxy)ethyl)-6-(2-methylpiperazin-1-yl)pyridazin-3(2H)-one
Show/Hide
|
C17H21ClN4O2
|
1
|
| 1 |
EC50 = 25 nM
|
|
|
|
CP0433761
|
(S)-2-(1-(2-chlorophenoxy)propan-2-yl)-6-(piperazin-1-yl)pyridazin-3(2H)-one
Show/Hide
|
C17H21ClN4O2
|
1
|
| 1 |
EC50 = 25 nM
|
|
|
|
CP0394858
|
10-[3-(3-Fluoro-phenoxy)-azetidin-1-yl]-6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene
Show/Hide
|
C19H20FN5O
|
1
|
| 1 |
EC50 = 25 nM
|
|
|
|
CP0310413
|
7-(3-(4-chlorophenoxy)azetidin-1-ylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Show/Hide
|
C19H21ClN2O3S
|
1
|
| 1 |
EC50 = 28 nM
|
|
|
|
CP0421550
|
2-benzyl-6,7,8,9-tetrahydro-2H-pyridazino[4,3-d]azepin-3(5H)-one
Show/Hide
|
C15H17N3O
|
1
|
| 1 |
EC50 = 30 nM
|
|
|
|
CP0090780
|
7-(4-(2-chlorophenoxy)piperidin-1-ylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Show/Hide
|
C21H25ClN2O3S
|
1
|
| 1 |
EC50 = 31 nM
|
|
|
|
CP0161903
|
(S)-7-(3-(2-chlorophenoxy)pyrrolidin-1-ylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Show/Hide
|
C20H23ClN2O3S
|
1
|
| 1 |
EC50 = 31 nM
|
|
|
|
CP0241830
|
7-(3-(2-chlorophenoxy)azetidin-1-ylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Show/Hide
|
C19H21ClN2O3S
|
1
|
| 1 |
EC50 = 31 nM
|
|
|
|
CP0181193
|
4-(2-benzyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-yl)morpholine
Show/Hide
|
C19H24N4O
|
1
|
| 1 |
EC50 = 33 nM
|
|
|
|
CP0407686
|
10-[3-(Pyridin-2-yloxy)-azetidin-1-yl]-6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene
Show/Hide
|
C18H20N6O
|
1
|
| 1 |
EC50 = 37 nM
|
|
|
|
CP0181190
|
2-benzyl-N-methyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine
Show/Hide
|
C16H20N4
|
1
|
| 1 |
EC50 = 39 nM
|
|
|
|
CP0270305
|
N-(2,3-dihydro-1-benzofuran-3-ylmethyl)-N-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7-sulfonamide
Show/Hide
|
C20H24N2O3S
|
1
|
| 1 |
EC50 = 41 nM
|
|
|
|
CP0422610
|
N-[(2-chlorophenyl)methyl]-2,3,4,5-tetrahydro-1H-3-benzazepine-7-sulfonamide
Show/Hide
|
C17H19ClN2O2S
|
1
|
| 1 |
EC50 = 46 nM
|
|
|
|
CP0399046
|
N,N-dimethyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7-sulfonamide
Show/Hide
|
C12H18N2O2S
|
1
|
| 1 |
EC50 = 47 nM
|
|
|
|
CP0398530
|
6-(piperazin-1-yl)-2-(2-(2-(trifluoromethyl)phenoxy)ethyl)pyridazin-3(2H)-one
Show/Hide
|
C17H19F3N4O2
|
1
|
| 1 |
EC50 = 47 nM
|
|
|
|
CP0378952
|
7-(pyrrolidin-1-ylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Show/Hide
|
C14H20N2O2S
|
1
|
| 1 |
EC50 = 50 nM
|
|
|
|
CP0203210
|
2-benzyl-4-methoxy-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine
Show/Hide
|
C16H19N3O
|
1
|
| 1 |
EC50 = 51 nM
|
|
|
|
CP0439393
|
N-ethyl-2,6,7,12-tetrazatricyclo[7.5.0.03,7]tetradeca-1,3,5,8-tetraen-8-amine
Show/Hide
|
C12H17N5
|
1
|
| 1 |
EC50 = 63 nM
|
|
|
|
CP0394691
|
10-[3-(3-Methoxy-phenoxy)-azetidin-1-yl]-6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene
Show/Hide
|
C20H23N5O2
|
1
|
| 1 |
EC50 = 65 nM
|
|
|
|
CP0477741
|
3-benzyl-1,5,6,7,8,9-hexahydropyrazino[2,3-d]azepin-2-one
Show/Hide
|
C15H17N3O
|
1
|
| 1 |
EC50 = 70 nM
|
|
|
|
CP0399045
|
N-(cyclopropylmethyl)-N-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7-sulfonamide
Show/Hide
|
C15H22N2O2S
|
1
|
| 1 |
EC50 = 71 nM
|
|
|
|
CP0378955
|
7-(4-fluorophenylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Show/Hide
|
C16H16FNO2S
|
1
|
| 1 |
EC50 = 80 nM
|
|
|
|
CP0399094
|
7-(piperidin-1-ylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Show/Hide
|
C15H22N2O2S
|
1
|
| 1 |
EC50 = 84 nM
|
|
|
|
CP0439382
|
10-[3-(2-Methoxy-phenoxy)-azetidin-1-yl]-6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene
Show/Hide
|
C20H23N5O2
|
1
|
| 1 |
EC50 = 84 nM
|
|
|
|
CP0090785
|
N-benzyl-N-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7-sulfonamide
Show/Hide
|
C18H22N2O2S
|
1
|
| 1 |
EC50 = 94 nM
|
|
|
|
CP0407617
|
10-[3-(4-Methoxy-phenoxy)-azetidin-1-yl]-6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene
Show/Hide
|
C20H23N5O2
|
1
|
| 1 |
EC50 = 95 nM
|
|
|
|
CP0438025
|
2-(4-methylbenzyl)-6,7,8,9-tetrahydro-5H-pyrimido[5,4-d]azepine
Show/Hide
|
C16H19N3
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0450982
|
2-(2-(2-bromophenoxy)ethyl)-6-(piperazin-1-yl)pyridazin-3(2H)-one
Show/Hide
|
C16H19BrN4O2
|
1
|
| 1 |
EC50 = 101 nM
|
|
|
|
CP0422032
|
2-phenethyl-6,7,8,9-tetrahydro-5H-pyrimido[5,4-d]azepine
Show/Hide
|
C16H19N3
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0485552
|
2-(2-(6-oxo-3-(piperazin-1-yl)pyridazin-1(6H)-yl)ethoxy)benzonitrile
Show/Hide
|
C17H19N5O2
|
1
|
| 1 |
EC50 = 114 nM
|
|
|
|
CP0422609
|
7-(4-(2-fluorophenoxy)piperidin-1-ylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Show/Hide
|
C21H25FN2O3S
|
1
|
| 1 |
EC50 = 115 nM
|
|
|
|
CP0377814
|
2-(3-fluorobenzyl)-6,7,8,9-tetrahydro-5H-pyrimido[5,4-d]azepine
Show/Hide
|
C15H16FN3
|
1
|
| 1 |
EC50 = 125 nM
|
|
|
|
CP0434097
|
3-benzyl-6,7,8,9-tetrahydro-5H-pyridazino[3,4-d]azepine
Show/Hide
|
C15H17N3
|
1
|
| 1 |
EC50 = 130 nM
|
|
|
|
CP0282245
|
2-benzyl-N,N-dimethyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine
Show/Hide
|
C17H22N4
|
1
|
| 1 |
EC50 = 154 nM
|
|
|
|
CP0405431
|
2-(2-(2-chlorophenoxy)ethyl)-6-(piperazin-1-yl)pyridazin-3(2H)-one
Show/Hide
|
C16H19ClN4O2
|
1
|
| 1 |
EC50 = 164 nM
|
|
|
|
CP0378954
|
N-benzyl-6,9-dimethoxy-N-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7-sulfonamide
Show/Hide
|
C20H26N2O4S
|
1
|
| 1 |
EC50 = 170 nM
|
|
|
|
CP0046618
|
1-(3-chlorophenyl)piperazine
Show/Hide
|
C10H13ClN2
|
1
|
| 1 |
EC50 = 170 nM
|
|
|
|
CP0377815
|
2-(3-chlorobenzyl)-6,7,8,9-tetrahydro-5H-pyrimido[5,4-d]azepine
Show/Hide
|
C15H16ClN3
|
1
|
| 1 |
EC50 = 180 nM
|
|
|
|
CP0423182
|
4-(2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylsulfonyl)morpholine
Show/Hide
|
C14H20N2O3S
|
1
|
| 1 |
EC50 = 186 nM
|
|
|
|
CP0394864
|
N-methyl-N-[4-[1-(2,6,7,12-tetrazatricyclo[7.5.0.03,7]tetradeca-1,3,5,8-tetraen-8-yl)azetidin-3-yl]oxyphenyl]acetamide
Show/Hide
|
C22H26N6O2
|
1
|
| 1 |
EC50 = 188 nM
|
|
|
|
CP0425904
|
2-(4-chlorobenzyl)-6,7,8,9-tetrahydro-5H-pyrimido[5,4-d]azepine
Show/Hide
|
C15H16ClN3
|
1
|
| 1 |
EC50 = 192 nM
|
|
|
|
CP0425905
|
2-(2-fluorobenzyl)-6,7,8,9-tetrahydro-5H-pyrimido[5,4-d]azepine
Show/Hide
|
C15H16FN3
|
1
|
| 1 |
EC50 = 194 nM
|
|
|
|
CP0399047
|
N-(2-fluorophenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7-sulfonamide
Show/Hide
|
C16H17FN2O2S
|
1
|
| 1 |
EC50 = 197 nM
|
|
|
|
CP0071447
|
(1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine
Show/Hide
|
C11H14ClN
|
1
|
| 1 |
EC50 = 210 nM
|
|
|
|
CP0495386
|
2-(3-methylbenzyl)-6,7,8,9-tetrahydro-5H-pyrimido[5,4-d]azepine
Show/Hide
|
C16H19N3
|
1
|
| 1 |
EC50 = 210 nM
|
|
|
|
CP0407685
|
10-[3-(Pyridin-3-yloxy)-azetidin-1-yl]-6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene
Show/Hide
|
C18H20N6O
|
1
|
| 1 |
EC50 = 211 nM
|
|
|
|
CP0528265
|
3-benzyl-4-methyl-6,7,8,9-tetrahydro-5H-pyridazino[3,4-d]azepine
Show/Hide
|
C16H19N3
|
1
|
| 1 |
EC50 = 220 nM
|
|
|
|
CP0399095
|
7-(4-(3-chlorophenoxy)piperidin-1-ylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Show/Hide
|
C21H25ClN2O3S
|
1
|
| 1 |
EC50 = 273 nM
|
|
|
|
CP0438024
|
2-(3-(trifluoromethyl)benzyl)-6,7,8,9-tetrahydro-5H-pyrimido[5,4-d]azepine
Show/Hide
|
C16H16F3N3
|
1
|
| 1 |
EC50 = 300 nM
|
|
|
|
CP0460720
|
2-(4-fluorobenzyl)-6,7,8,9-tetrahydro-5H-pyrimido[5,4-d]azepine
Show/Hide
|
C15H16FN3
|
1
|
| 1 |
EC50 = 310 nM
|
|
|
|
CP0477755
|
3-[(4-chlorophenyl)methyl]-6,7,8,9-tetrahydro-5H-pyridazino[3,4-d]azepine
Show/Hide
|
C15H16ClN3
|
1
|
| 1 |
EC50 = 310 nM
|
|
|
|
CP0532914
|
3-[(2-chlorophenyl)methyl]-6,7,8,9-tetrahydro-5H-pyridazino[3,4-d]azepine
Show/Hide
|
C15H16ClN3
|
1
|
| 1 |
EC50 = 310 nM
|
|
|
|
CP0460721
|
2-(2-methylbenzyl)-6,7,8,9-tetrahydro-5H-pyrimido[5,4-d]azepine
Show/Hide
|
C16H19N3
|
1
|
| 1 |
EC50 = 330 nM
|
|
|
|
CP0405434
|
(S)-2-(2-(2-chlorophenoxy)propyl)-6-(piperazin-1-yl)pyridazin-3(2H)-one
Show/Hide
|
C17H21ClN4O2
|
1
|
| 1 |
EC50 = 360 nM
|
|
|
|
CP0411807
|
N-ethyl-N-methyl-2,6,7,12-tetrazatricyclo[7.5.0.03,7]tetradeca-1,3,5,8-tetraen-8-amine
Show/Hide
|
C13H19N5
|
1
|
| 1 |
EC50 = 362 nM
|
|
|
|
CP0436916
|
7-(4-(2-chlorophenoxy)piperidin-1-ylsulfonyl)-6,9-dimethoxy-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Show/Hide
|
C23H29ClN2O5S
|
1
|
| 1 |
EC50 = 365 nM
|
|
|
|
CP0377817
|
2-phenyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine
Show/Hide
|
C13H13N3
|
1
|
| 1 |
EC50 = 380 nM
|
|
|
|
CP0485550
|
(R)-2-(2-(2-chlorophenoxy)ethyl)-6-(2-ethylpiperazin-1-yl)pyridazin-3(2H)-one
Show/Hide
|
C18H23ClN4O2
|
1
|
| 1 |
EC50 = 407 nM
|
|
|
|
CP0436147
|
7-(4-phenoxypiperidin-1-ylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Show/Hide
|
C21H26N2O3S
|
1
|
| 1 |
EC50 = 508 nM
|
|
|
|
CP0433757
|
2-(2-(2-chlorophenoxy)ethyl)-5-methyl-6-(piperazin-1-yl)pyridazin-3(2H)-one
Show/Hide
|
C17H21ClN4O2
|
1
|
| 1 |
EC50 = 510 nM
|
|
|
|
CP0468202
|
10-[3-(Pyridin-4-yloxy)-azetidin-1-yl]-6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene
Show/Hide
|
C18H20N6O
|
1
|
| 1 |
EC50 = 574 nM
|
|
|
|
CP0493548
|
N-(cyclopropylmethyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7-sulfonamide
Show/Hide
|
C14H20N2O2S
|
1
|
| 1 |
EC50 = 631 nM
|
|
|
|
CP0372291
|
N-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7-sulfonamide
Show/Hide
|
C16H18N2O2S
|
1
|
| 1 |
EC50 = 697 nM
|
|
|
|
CP0439984
|
3-[[3-(trifluoromethyl)phenyl]methyl]-6,7,8,9-tetrahydro-5H-pyridazino[3,4-d]azepine
Show/Hide
|
C16H16F3N3
|
1
|
| 1 |
EC50 = 750 nM
|
|
|
|
CP0407618
|
10-Pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene
Show/Hide
|
C14H19N5
|
1
|
| 1 |
EC50 = 764 nM
|
|
|
|
CP0402149
|
N-(2-chlorophenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7-sulfonamide
Show/Hide
|
C16H17ClN2O2S
|
1
|
| 1 |
EC50 = 857 nM
|
|
|
|
CP0461664
|
(R)-2-(2-(2-chlorophenoxy)propyl)-6-(piperazin-1-yl)pyridazin-3(2H)-one
Show/Hide
|
C17H21ClN4O2
|
1
|
| 1 |
EC50 = 858 nM
|
|
|
|
CP0378953
|
N-propyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7-sulfonamide
Show/Hide
|
C13H20N2O2S
|
1
|
| 1 |
EC50 = 959 nM
|
|
|
|
CP0229014
|
2-benzyl-3,5,6,7,8,9-hexahydropyrimido[4,5-d]azepin-4-one
Show/Hide
|
C15H17N3O
|
1
|
| 1 |
EC50 = 1460 nM
|
|
|
|
CP0507729
|
2-(3-phenylpropyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine
Show/Hide
|
C16H19N3
|
1
|
| 1 |
EC50 = 1900 nM
|
|
|
|
CP0426448
|
10-Piperidin-1-yl-6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene
Show/Hide
|
C15H21N5
|
1
|
| 1 |
EC50 = 4564 nM
|
|
|
|
CP0477779
|
2-benzyl-2,4,5,6,7,8-hexahydropyrazolo[4,3-d]azepine
Show/Hide
|
C14H17N3
|
1
|
| 1 |
EC50 = 4980 nM
|
|
|
|
CP0418154
|
2-(2-phenoxyethyl)-6-(piperazin-1-yl)pyridazin-3(2H)-one
Show/Hide
|
C16H20N4O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0433758
|
(S)-2-(2-(2-chlorophenoxy)ethyl)-6-(3-methylpiperazin-1-yl)pyridazin-3(2H)-one
Show/Hide
|
C17H21ClN4O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0461662
|
2-(2-(2-chlorophenoxy)ethyl)-4-(piperazin-1-yl)-2,5,6,7-tetrahydro-1H-cyclopenta[d]pyridazin-1-one
Show/Hide
|
C19H23ClN4O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0473840
|
(S)-2-(2-(2-chlorophenoxy)ethyl)-6-(2-methylpiperazin-1-yl)pyridazin-3(2H)-one
Show/Hide
|
C17H21ClN4O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0485665
|
2-(2-(2-chlorophenoxy)ethyl)-4-methyl-6-(piperazin-1-yl)pyridazin-3(2H)-one
Show/Hide
|
C17H21ClN4O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0534457
|
2-(2-(4-chlorophenoxy)ethyl)-6-(piperazin-1-yl)pyridazin-3(2H)-one
Show/Hide
|
C16H19ClN4O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0534458
|
2-(2-(3-chlorophenoxy)ethyl)-6-(piperazin-1-yl)pyridazin-3(2H)-one
Show/Hide
|
C16H19ClN4O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0540071
|
2-(2-(2-methoxyphenoxy)ethyl)-6-(piperazin-1-yl)pyridazin-3(2H)-one
Show/Hide
|
C17H22N4O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0129854
|
2-benzyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine
Show/Hide
|
C15H18N4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0181188
|
2-benzyl-N-ethyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine
Show/Hide
|
C17H22N4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0417970
|
N-methyl-2-(1-phenylcyclopropyl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine
Show/Hide
|
C18H22N4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0461313
|
(9R)-2-benzyl-N,9-dimethyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine
Show/Hide
|
C17H22N4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0497371
|
N-methyl-2-(2-phenylpropan-2-yl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine
Show/Hide
|
C18H24N4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0434096
|
3-[(4-fluorophenyl)methyl]-6,7,8,9-tetrahydro-5H-pyridazino[3,4-d]azepine
Show/Hide
|
C15H16FN3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0439985
|
1-benzyl-1,2,5,6,7,8-hexahydropyrazolo[4,3-d]azepin-3(4H)-one
Show/Hide
|
C14H17N3O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0469839
|
2-benzyl-1,2,5,6,7,8-hexahydropyrazolo[4,3-d]azepin-3(4H)-one
Show/Hide
|
C14H17N3O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0477743
|
3-[(2-methoxyphenyl)methyl]-6,7,8,9-tetrahydro-5H-pyridazino[3,4-d]azepine
Show/Hide
|
C16H19N3O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0477780
|
1-benzyl-1,4,5,6,7,8-hexahydropyrazolo[4,3-d]azepine
Show/Hide
|
C14H17N3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0532915
|
3-benzyl-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-d][1,4]diazepine
Show/Hide
|
C13H16N4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0405433
|
(R)-2-(1-(2-chlorophenoxy)propan-2-yl)-6-(piperazin-1-yl)pyridazin-3(2H)-one
Show/Hide
|
C17H21ClN4O2
|
1
|
| 1 |
EC50 > 1920 nM
|
|
|
|
CP0374108
|
2-(2-(2,3-dichlorophenoxy)ethyl)-6-(piperazin-1-yl)pyridazin-3(2H)-one
Show/Hide
|
C16H18Cl2N4O2
|
1
|
| 1 |
EC50 > 2130 nM
|
|
|
|
CP0472238
|
6-(piperazin-1-yl)-2-(2-(o-tolyloxy)ethyl)pyridazin-3(2H)-one
Show/Hide
|
C17H22N4O2
|
1
|
| 1 |
EC50 > 4550 nM
|
|
|
|
CP0041613
|
Anapriline
Show/Hide
|
C16H21NO2
|
2
|
| 1 |
EC50 > 5011.87 nM
|
|
|
| 2 |
IC50 > 5011.87 nM
|
|
|
|
CP0066236
|
1-(dimethylamino)-3-[(2-methyl-1H-1,2-benzazaborinin-8-yl)oxy]propan-2-ol
Show/Hide
|
C14H21BN2O2
|
2
|
| 1 |
EC50 > 5011.87 nM
|
|
|
| 2 |
IC50 > 5011.87 nM
|
|
|
|
CP0366351
|
1-(dimethylamino)-3-[(2-methyl-1H-1,2-benzazaborinin-5-yl)oxy]propan-2-ol
Show/Hide
|
C14H21BN2O2
|
2
|
| 1 |
EC50 > 5011.87 nM
|
|
|
| 2 |
IC50 > 5011.87 nM
|
|
|
|
CP0418152
|
1-(1-(2-(2-chlorophenoxy)ethyl)-6-oxo-1,6-dihydropyridazin-3-yl)piperazine-2-carbaldehyde
Show/Hide
|
C17H19ClN4O3
|
1
|
| 1 |
EC50 > 9980 nM
|
|
|
|
CP0211700
|
1H-indole-3-carboxylic acid[6-(2-chloro-pyridin-3-yloxy)-pyridin-3-yl]-amide
Show/Hide
|
C19H13ClN4O2
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0096796
|
5-Methyl-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid [6-(2-methyl-pyridin-3-yloxy)-pyridin-3-yl]-amide
Show/Hide
|
C22H19F3N4O2
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0199101
|
N-(6-pyridin-3-yloxypyridin-3-yl)-1H-indole-3-carboxamide
Show/Hide
|
C19H14N4O2
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0082221
|
6-methyl-N-(6-(2-methylpyridin-3-yloxy)pyridin-3-yl)-1H-indole-3-carboxamide
Show/Hide
|
C21H18N4O2
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
|
CP0724162
|
2-Benzyl-N-phenyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine-4-amine hydrochloride
Show/Hide
|
C21H23ClN4
|
1
|
| 1 |
IC50 = 1.98 nM
|
|
|
|
CP0674236
|
2-Benzyl-N-(3-chlorophenyl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine-4-amine hydrochloride
Show/Hide
|
C21H22Cl2N4
|
1
|
| 1 |
IC50 = 2.3 nM
|
|
|
|
CP0398640
|
N-[3-(4-methylpiperazin-1-yl)phenyl]-N-propan-2-ylnaphthalene-2-sulfonamide
Show/Hide
|
C24H29N3O2S
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0082222
|
5-methyl-N-(6-(2-methylpyridin-3-yloxy)pyridin-3-yl)-1H-indole-3-carboxamide
Show/Hide
|
C21H18N4O2
|
1
|
| 1 |
IC50 = 4.5 nM
|
|
|
|
CP0489835
|
N-[6-(pyridin-2-ylmethoxy)pyridin-3-yl]-1H-indole-3-carboxamide
Show/Hide
|
C20H16N4O2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0416326
|
N-(cyclopropylmethyl)-N-[3-(4-methylpiperazin-1-yl)phenyl]naphthalene-2-sulfonamide
Show/Hide
|
C25H29N3O2S
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0487098
|
N-[3-(4-methylpiperazin-1-yl)phenyl]-N-propylnaphthalene-2-sulfonamide
Show/Hide
|
C24H29N3O2S
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0131104
|
5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid (3-pyridin-3-yl-phenyl)-amide
Show/Hide
|
C22H18F3N3O2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0374085
|
N-(3-methoxyphenyl)-1-methyl-6-(4-methylpiperazin-1-yl)pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
|
C18H23N7O
|
1
|
| 1 |
IC50 = 7.8 nM
|
|
|
|
CP0857451
|
N-(3-methoxyphenyl)-6-(4-methylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
|
C17H21N7O
|
1
|
| 1 |
IC50 = 7.8 nM
|
|
|
|
CP0505204
|
7-methyl-N-(6-(2-methylpyridin-3-yloxy)pyridin-3-yl)-1H-indole-3-carboxamide
Show/Hide
|
C21H18N4O2
|
1
|
| 1 |
IC50 = 8.2 nM
|
|
|
|
CP0912053
|
2-Benzyl-N-(4-fluorophenyl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine-4-amine hydrochloride
Show/Hide
|
C21H22ClFN4
|
1
|
| 1 |
IC50 = 8.5 nM
|
|
|
|
CP0053024
|
5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid (3-bromo-5-pyridin-3-yl-phenyl)-amide
Show/Hide
|
C22H17BrF3N3O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0099734
|
5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid (3-fluoro-5-pyridin-3-yl-phenyl)-amide
Show/Hide
|
C22H17F4N3O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0545777
|
5-methoxy-N-[3-pyridin-3-yl-5-(trifluoromethyl)phenyl]-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C23H17F6N3O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0164226
|
5-methoxy-N-(6-(2-methylpyridin-3-yloxy)pyridin-3-yl)-1H-indole-3-carboxamide
Show/Hide
|
C21H18N4O3
|
1
|
| 1 |
IC50 = 10.7 nM
|
|
|
|
CP0509306
|
N-(cyclopentylmethyl)-N-[3-(4-methylpiperazin-1-yl)phenyl]naphthalene-2-sulfonamide
Show/Hide
|
C27H33N3O2S
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0039201
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-1,2-dimethyl-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C26H30Cl2N4O
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0497140
|
N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-N,2-dimethyl-5-phenyl-1-propylpyrrole-3-carboxamide
Show/Hide
|
C31H42N4O
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0673546
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-2,5-dimethyl-1-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C25H33Cl6N5O
|
1
|
| 1 |
IC50 = 12.1 nM
|
|
|
|
CP0402995
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-2,5-dimethyl-1-phenylimidazole-4-carboxamide
Show/Hide
|
C25H29Cl2N5O
|
1
|
| 1 |
IC50 = 12.1 nM
|
|
|
|
CP0912473
|
N-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl)ethyl)-2,4-dimethyl-5-phenyl-1H-pyrrole-3-carboxamide hydrochloride
Show/Hide
|
C25H29Cl3N4O
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0673445
|
2-Benzyl-N-(3-fluorophenyl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine-4-amine hydrochloride
Show/Hide
|
C21H22ClFN4
|
1
|
| 1 |
IC50 = 13.3 nM
|
|
|
|
CP0852994
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C27H35Cl6N5O3
|
1
|
| 1 |
IC50 = 14.6 nM
|
|
|
|
CP0434338
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-2,5-dimethylimidazole-4-carboxamide
Show/Hide
|
C27H31Cl2N5O3
|
1
|
| 1 |
IC50 = 14.6 nM
|
|
|
|
CP0861032
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-1,2,4-trimethyl-5-phenyl-1H-pyrrole-3-carboxamide hydrochloride
Show/Hide
|
C26H31Cl3N4O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0912474
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-2,4-dimethyl-5-phenyl-1H-pyrrole-3-carboxamide hydrochloride
Show/Hide
|
C26H31Cl3N4O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0416325
|
N-ethyl-N-[3-(4-methylpiperazin-1-yl)phenyl]naphthalene-2-sulfonamide
Show/Hide
|
C23H27N3O2S
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0374084
|
N-(4-fluorophenyl)-1-methyl-6-(4-methylpiperazin-1-yl)pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
|
C17H20FN7
|
1
|
| 1 |
IC50 = 20.1 nM
|
|
|
|
CP0373839
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-2-methyl-5-phenyl-1-propylpyrrole-3-carboxamide
Show/Hide
|
C29H36Cl2N4O
|
1
|
| 1 |
IC50 = 20.9 nM
|
|
|
|
CP0918850
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-N,2-dimethyl-5-phenyl-1-propyl-1H-pyrrole-3-carboxamide hydrochloride
Show/Hide
|
C29H37Cl3N4O
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0417858
|
N-[3-(4-methylpiperazin-1-yl)phenyl]-N-propan-2-ylbenzenesulfonamide
Show/Hide
|
C20H27N3O2S
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0912475
|
5-(4-Chlorophenyl)-N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)-1-ethyl-2-methyl-1H-pyrrole-3-carboxamidehydrochloride
Show/Hide
|
C27H32Cl4N4O
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0447670
|
N-(cyclohexylmethyl)-N-[3-[4-(4-fluorophenyl)piperazin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
|
C30H38FN3O2S
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0903271
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-1-(2-methoxyphenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C26H35Cl6N5O2
|
1
|
| 1 |
IC50 = 25.5 nM
|
|
|
|
CP0443120
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-1-(2-methoxyphenyl)-2,5-dimethylimidazole-4-carboxamide
Show/Hide
|
C26H31Cl2N5O2
|
1
|
| 1 |
IC50 = 25.5 nM
|
|
|
|
CP0916529
|
5-(4-Chlorophenyl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-2-methyl-1-propyl-1H-pyrrole-3-carboxamide hydrochloride
Show/Hide
|
C30H40Cl2N4O
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0420234
|
US8835436, Example 115
Show/Hide
|
C27H33N5O3
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0494262
|
N-(4-chlorophenyl)-1-methyl-6-(4-methylpiperazin-1-yl)pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
|
C17H20ClN7
|
1
|
| 1 |
IC50 = 29.4 nM
|
|
|
|
CP0876522
|
N-(4-chlorophenyl)-6-(4-methylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
|
C16H18ClN7
|
1
|
| 1 |
IC50 = 29.4 nM
|
|
|
|
CP0918740
|
N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)-2-methyl-6-phenylpyrimidine-4-carboxamide hydrochloride
Show/Hide
|
C25H28Cl3N5O
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0390407
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-1,2-dimethyl-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C27H32Cl2N4O
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0417851
|
N-benzyl-N-[3-(4-methylpiperazin-1-yl)phenyl]naphthalene-2-sulfonamide
Show/Hide
|
C28H29N3O2S
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0373407
|
N-(cyclohexylmethyl)-4-methoxy-N-[3-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]propyl]benzenesulfonamide
Show/Hide
|
C28H38F3N3O3S
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0510351
|
N-[3-(4-methylpiperazin-1-yl)phenyl]-N-(pyridin-3-ylmethyl)naphthalene-2-sulfonamide
Show/Hide
|
C27H28N4O2S
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0875091
|
1-(4-Chlorophenyl)-N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C26H35Cl8N5O
|
1
|
| 1 |
IC50 = 34.6 nM
|
|
|
|
CP0472050
|
US8835436, Example 2
Show/Hide
|
C13H15N3
|
1
|
| 1 |
IC50 = 34.6 nM
|
|
|
|
CP0513546
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-N,1,2-trimethyl-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C27H32Cl2N4O
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0377202
|
N-methyl-N-[3-(4-methylpiperazin-1-yl)phenyl]naphthalene-2-sulfonamide
Show/Hide
|
C22H25N3O2S
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0373838
|
N-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]-2-methyl-5-phenyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C24H26Cl2N4O
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0673446
|
2-Benzyl-N-(3-methoxyphenyl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine-4-amine hydrochloride
Show/Hide
|
C22H25ClN4O
|
1
|
| 1 |
IC50 = 37.3 nM
|
|
|
|
CP0930888
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-1-(2-methoxyphenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C27H37Cl4N5O2
|
1
|
| 1 |
IC50 = 37.4 nM
|
|
|
|
CP0486579
|
N-[3-[4-(3-chloro-2-methylphenyl)piperazin-1-yl]propyl]-1-(2-methoxyphenyl)-2,5-dimethylimidazole-4-carboxamide
Show/Hide
|
C27H34ClN5O2
|
1
|
| 1 |
IC50 = 37.4 nM
|
|
|
|
CP0875090
|
1-(4-Chlorophenyl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C28H39Cl4N5O
|
1
|
| 1 |
IC50 = 37.9 nM
|
|
|
|
CP0456781
|
1-(4-chlorophenyl)-N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-2-propylimidazole-4-carboxamide
Show/Hide
|
C28H36ClN5O
|
1
|
| 1 |
IC50 = 37.9 nM
|
|
|
|
CP0497110
|
N-(cyclohexylmethyl)-N-[3-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]propyl]quinoline-8-sulfonamide
Show/Hide
|
C30H37F3N4O2S
|
1
|
| 1 |
IC50 = 38.8 nM
|
|
|
|
CP0372470
|
5-(4-Chlorophenyl)-N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)-1,2-dimethyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C26H29Cl3N4O
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0916528
|
5-(4-Chlorophenyl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-1-ethyl-2-methyl-1H-pyrrole-3-carboxamide hydrochloride
Show/Hide
|
C29H38Cl2N4O
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0853000
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-1-(2-chlorophenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C26H35Cl6N5O
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0464923
|
US8835436, Example 103
Show/Hide
|
C28H36ClN5O
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0510691
|
N-(cyclohexylmethyl)-N-[3-[4-(4-fluorophenyl)piperazin-1-yl]propyl]-4-methoxybenzenesulfonamide
Show/Hide
|
C27H38FN3O3S
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0844938
|
5-(4-Chlorophenyl)-N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)-2-methyl-1-propyl-1H-pyrrole-3-carboxamidehydrochloride
Show/Hide
|
C28H34Cl4N4O
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0401996
|
N-(cyclohexylmethyl)-4-nitro-N-[3-(4-phenylpiperazin-1-yl)propyl]benzenesulfonamide
Show/Hide
|
C26H36N4O4S
|
1
|
| 1 |
IC50 = 45.7 nM
|
|
|
|
CP0527405
|
US8835436, Example 114
Show/Hide
|
C26H32FN5O
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0476394
|
N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-1-benzothiophene-3-carboxamide
Show/Hide
|
C20H15N3O2S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0493710
|
N-(6-pyrimidin-5-yloxypyridin-3-yl)-1H-indole-3-carboxamide
Show/Hide
|
C18H13N5O2
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0282663
|
5-methoxy-N-[3-pyridin-3-yl-5-(trifluoromethoxy)phenyl]-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C23H17F6N3O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0514881
|
N-(cyclohexylmethyl)-N-[3-(4-phenylpiperazin-1-yl)propyl]naphthalene-1-sulfonamide
Show/Hide
|
C30H39N3O2S
|
1
|
| 1 |
IC50 = 50.7 nM
|
|
|
|
CP0908964
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-1-(2-fluorophenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C25H32Cl6FN5O
|
1
|
| 1 |
IC50 = 50.8 nM
|
|
|
|
CP0414724
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-1-(2-fluorophenyl)-2,5-dimethylimidazole-4-carboxamide
Show/Hide
|
C25H28Cl2FN5O
|
1
|
| 1 |
IC50 = 50.8 nM
|
|
|
|
CP0500061
|
4-butoxy-N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
Show/Hide
|
C17H28N2O3S
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
|
CP0419080
|
4-Methoxy-N-{3-[4-(m-trifluoromethylphenyl)-piperazin-1-yl]-propyl}-benzenesulfonamide
Show/Hide
|
C21H26F3N3O3S
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
|
CP0505206
|
N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-1H-indole-2-carboxamide
Show/Hide
|
C20H16N4O2
|
1
|
| 1 |
IC50 = 59 nM
|
|
|
|
CP0409927
|
US8835436, Example 113
Show/Hide
|
C28H37N5O
|
1
|
| 1 |
IC50 = 59 nM
|
|
|
|
CP0373841
|
N-[4-[4-(2,3-dimethylphenyl)piperazin-1-yl]butyl]-1,2-dimethyl-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C29H38N4O
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0871161
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C30H41Cl4N5O3
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0858681
|
N-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl)ethyl)-2-ethyl-5-methyl-1-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C25H33Cl6N5O
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0527457
|
N-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]-2-ethyl-5-methyl-1-phenylimidazole-4-carboxamide
Show/Hide
|
C25H29Cl2N5O
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0382888
|
N-[4-[4-(2,3-dimethylphenyl)piperazin-1-yl]butyl]-2-methyl-5-phenyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C28H36N4O
|
1
|
| 1 |
IC50 = 63 nM
|
|
|
|
CP0441409
|
US8835436, Example 112
Show/Hide
|
C28H37N5O3
|
1
|
| 1 |
IC50 = 63 nM
|
|
|
|
CP0470731
|
N-[2-[4-(3-chloro-2-methylphenyl)piperazin-1-yl]ethyl]-1,2-dimethyl-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C26H31ClN4O
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
|
CP0847161
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-fluorophenyl)-5-methyl-2-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C30H34Cl6FN5O2
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
|
CP0858684
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-1-(4-methoxyphenyl)-5-methyl-2-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C31H37Cl6N5O2
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
|
CP0871052
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-1-(4-fluorophenyl)-5-methyl-2-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C32H38Cl2FN5O
|
1
|
| 1 |
IC50 = 64.1 nM
|
|
|
|
CP0477664
|
N-(cyclohexylmethyl)-N-[3-(4-phenylpiperazin-1-yl)propyl]naphthalene-2-sulfonamide
Show/Hide
|
C30H39N3O2S
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0400310
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-1-ethyl-2-methyl-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C27H32Cl2N4O
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0502301
|
N-(cyclohexylmethyl)-N-[3-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
|
C31H38F3N3O2S
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0668069
|
N-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl)ethyl)-2,5-dimethyl-1-phenyl-1Himidazole-4-carboxamide dihydrochloride
Show/Hide
|
C24H31Cl6N5O
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0412633
|
N-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]-2,5-dimethyl-1-phenylimidazole-4-carboxamide
Show/Hide
|
C24H27Cl2N5O
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0492830
|
N-(cyclohexylmethyl)-N-[3-[4-(3,4-dichlorophenyl)piperazin-1-yl]propyl]quinoline-8-sulfonamide
Show/Hide
|
C29H36Cl2N4O2S
|
1
|
| 1 |
IC50 = 66.5 nM
|
|
|
|
CP0493712
|
N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-1H-indole-3-carboxamide
Show/Hide
|
C20H16N4O2
|
1
|
| 1 |
IC50 = 67 nM
|
|
|
|
CP0847156
|
1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-5-methyl-2-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C34H41Cl2N5O3
|
1
|
| 1 |
IC50 = 68 nM
|
|
|
|
CP0857567
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-1-(4-fluorophenyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C29H40Cl2FN5O
|
1
|
| 1 |
IC50 = 68 nM
|
|
|
|
CP0430835
|
N-(cyclohexylmethyl)-N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
|
C31H41N3O3S
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0917394
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-1-(2-fluorophenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C26H34Cl4FN5O
|
1
|
| 1 |
IC50 = 71 nM
|
|
|
|
CP0390294
|
N-[3-[4-(3-chloro-2-methylphenyl)piperazin-1-yl]propyl]-1-(2-fluorophenyl)-2,5-dimethylimidazole-4-carboxamide
Show/Hide
|
C26H31ClFN5O
|
1
|
| 1 |
IC50 = 71 nM
|
|
|
|
CP0861033
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-2,4-dimethyl-5-phenyl-1-propyl-1H-pyrrole-3-carboxamide hydrochloride
Show/Hide
|
C28H35Cl3N4O
|
1
|
| 1 |
IC50 = 75 nM
|
|
|
|
CP0853005
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(2-methoxyphenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C26H35Cl6N5O3
|
1
|
| 1 |
IC50 = 76.6 nM
|
|
|
|
CP0453995
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]-2-hydroxypropyl]-1-(2-methoxyphenyl)-2,5-dimethylimidazole-4-carboxamide
Show/Hide
|
C26H31Cl2N5O3
|
1
|
| 1 |
IC50 = 76.6 nM
|
|
|
|
CP0887878
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-1-(4-methoxyphenyl)-5-methyl-2-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C32H39Cl4N5O2
|
1
|
| 1 |
IC50 = 77 nM
|
|
|
|
CP0463160
|
US8835436, Example 147
Show/Hide
|
C28H37N5O
|
1
|
| 1 |
IC50 = 78.1 nM
|
|
|
|
CP0502603
|
N-(cyclohexylmethyl)-4-methoxy-N-[3-(4-phenylpiperazin-1-yl)propyl]benzenesulfonamide
Show/Hide
|
C27H39N3O3S
|
1
|
| 1 |
IC50 = 79 nM
|
|
|
|
CP0860116
|
N-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)-6-methyl-2-(methylthio)pyrimidine-4-carboxamide hydrochloride
Show/Hide
|
C19H24Cl3N5OS
|
1
|
| 1 |
IC50 = 81 nM
|
|
|
|
CP0846048
|
N-(4-fluorophenyl)-6-(4-methylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
|
C16H18FN7
|
1
|
| 1 |
IC50 = 85.8 nM
|
|
|
|
CP0470732
|
5-tert-Butyl-N-(2-(4-(3-chloro-2-methylphenyl)piperazin-1-yl)ethyl)-1,2-dimethyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C24H35ClN4O
|
1
|
| 1 |
IC50 = 86.15 nM
|
|
|
|
CP0252612
|
1-methyl-6-(4-methylpiperazin-1-yl)-N-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
|
C17H21N7
|
1
|
| 1 |
IC50 = 86.9 nM
|
|
|
|
CP0846049
|
6-(4-methylpiperazin-1-yl)-N-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
|
C16H19N7
|
1
|
| 1 |
IC50 = 86.9 nM
|
|
|
|
CP0910744
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-1-(4-methoxyphenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C26H35Cl6N5O2
|
1
|
| 1 |
IC50 = 88 nM
|
|
|
|
CP0486576
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-1-(4-methoxyphenyl)-2,5-dimethylimidazole-4-carboxamide
Show/Hide
|
C26H31Cl2N5O2
|
1
|
| 1 |
IC50 = 88 nM
|
|
|
|
CP0510686
|
N-[4-[4-(4-fluorophenyl)piperazin-1-yl]butan-2-yl]naphthalene-2-sulfonamide
Show/Hide
|
C24H28FN3O2S
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0419082
|
N-[3-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
|
C24H26F3N3O2S
|
1
|
| 1 |
IC50 = 91 nM
|
|
|
|
CP0470730
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-1,2-dimethyl-5-pyridin-3-ylpyrrole-3-carboxamide
Show/Hide
|
C25H29Cl2N5O
|
1
|
| 1 |
IC50 = 92 nM
|
|
|
|
CP0871051
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-1-(4-methoxyphenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C27H37Cl4N5O2
|
1
|
| 1 |
IC50 = 93.6 nM
|
|
|
|
CP0402822
|
N-[3-[4-(3-chloro-2-methylphenyl)piperazin-1-yl]propyl]-1-(4-methoxyphenyl)-2,5-dimethylimidazole-4-carboxamide
Show/Hide
|
C27H34ClN5O2
|
1
|
| 1 |
IC50 = 93.6 nM
|
|
|
|
CP0919600
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C27H35Cl6N5O4
|
1
|
| 1 |
IC50 = 94.3 nM
|
|
|
|
CP0473479
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]-2-hydroxypropyl]-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-2,5-dimethylimidazole-4-carboxamide
Show/Hide
|
C27H31Cl2N5O4
|
1
|
| 1 |
IC50 = 94.3 nM
|
|
|
|
CP0852998
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-1-(4-methoxyphenyl)-5-methyl-2-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C33H41Cl2N5O2
|
1
|
| 1 |
IC50 = 96 nM
|
|
|
|
CP0545507
|
N-[3-(4-methylpiperazin-1-yl)phenyl]-N-propan-2-ylnaphthalene-1-carboxamide
Show/Hide
|
C25H29N3O
|
1
|
| 1 |
IC50 = 97 nM
|
|
|
|
CP0427522
|
N-methyl-N-(1-methylpiperidin-4-yl)naphthalene-1-sulfonamide
Show/Hide
|
C17H22N2O2S
|
1
|
| 1 |
IC50 = 99 nM
|
|
|
|
CP0398637
|
N-[3-(4-methylpiperazin-1-yl)phenyl]-N-propan-2-ylnaphthalene-1-sulfonamide
Show/Hide
|
C24H29N3O2S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0420028
|
N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-1-(4-methoxyphenyl)-2-phenylimidazole-4-carboxamide
Show/Hide
|
C32H37N5O2
|
1
|
| 1 |
IC50 = 101 nM
|
|
|
|
CP0919010
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-1-phenyl-2-propyl-1Himidazole-4-carboxamide dihydrochloride
Show/Hide
|
C28H39Cl2N5O
|
1
|
| 1 |
IC50 = 103 nM
|
|
|
|
CP0429646
|
N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-1-phenyl-2-propylimidazole-4-carboxamide
Show/Hide
|
C28H37N5O
|
1
|
| 1 |
IC50 = 103 nM
|
|
|
|
CP0857566
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-1-(4-methoxyphenyl)-2-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C32H39Cl2N5O2
|
1
|
| 1 |
IC50 = 104 nM
|
|
|
|
CP0914752
|
5-(4-Chlorophenyl)-N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)-2-methyl-1H-pyrrole-3-carboxamide hydrochloride
Show/Hide
|
C25H28Cl4N4O
|
1
|
| 1 |
IC50 = 106 nM
|
|
|
|
CP0514856
|
4-methyl-N-[3-(4-methylpiperazin-1-yl)phenyl]-N-propan-2-ylbenzenesulfonamide
Show/Hide
|
C21H29N3O2S
|
1
|
| 1 |
IC50 = 106 nM
|
|
|
|
CP0871160
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C28H37Cl4N5O3
|
1
|
| 1 |
IC50 = 106 nM
|
|
|
|
CP0844940
|
5-tert-Butyl-N-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)-1,2-dimethyl-1H-pyrrole-3-carboxamide hydrochloride
Show/Hide
|
C23H33Cl3N4O
|
1
|
| 1 |
IC50 = 109 nM
|
|
|
|
CP0894532
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-5-methyl-1,2-diphenyl-1H-imidazole-4-carboxamide Dihydrochloride
Show/Hide
|
C30H35Cl6N5O
|
1
|
| 1 |
IC50 = 109 nM
|
|
|
|
CP0904461
|
N-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl)ethyl)-5-methyl-1-phenyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C26H35Cl6N5O
|
1
|
| 1 |
IC50 = 109 nM
|
|
|
|
CP0429821
|
N-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]-5-methyl-1-phenyl-2-propylimidazole-4-carboxamide
Show/Hide
|
C26H31Cl2N5O
|
1
|
| 1 |
IC50 = 109 nM
|
|
|
|
CP0887879
|
1-(3-Chlorophenyl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C27H37Cl4N5O
|
1
|
| 1 |
IC50 = 110.6 nM
|
|
|
|
CP0847154
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-1-(4-fluorophenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C26H34Cl4FN5O
|
1
|
| 1 |
IC50 = 113 nM
|
|
|
|
CP0871154
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-1,2-diphenyl-1Himidazole-4-carboxamide dihydrochloride
Show/Hide
|
C31H37Cl2N5O
|
1
|
| 1 |
IC50 = 116 nM
|
|
|
|
CP0430836
|
N-(cyclohexylmethyl)-N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]quinoline-8-sulfonamide
Show/Hide
|
C30H40N4O3S
|
1
|
| 1 |
IC50 = 117.9 nM
|
|
|
|
CP0487923
|
6-methoxy-N-[3-pyridin-3-yl-5-(trifluoromethoxy)phenyl]-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C22H18F3N3O3
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0852999
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-1-(2-fluorophenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C27H36Cl2FN5O
|
1
|
| 1 |
IC50 = 124 nM
|
|
|
|
CP0891571
|
1-(4-Chlorophenyl)-N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C25H33Cl8N5O
|
1
|
| 1 |
IC50 = 127 nM
|
|
|
|
CP0413785
|
US8835436, Example 11
Show/Hide
|
C25H28Cl3N5O
|
1
|
| 1 |
IC50 = 127 nM
|
|
|
|
CP0902449
|
5-(4-Chlorophenyl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-1,2-dimethyl-1H-pyrrole-3-carboxamide hydrochloride
Show/Hide
|
C28H36Cl2N4O
|
1
|
| 1 |
IC50 = 129 nM
|
|
|
|
CP0852997
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-1-(4-methoxyphenyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C30H43Cl2N5O2
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0573741
|
N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-1-(4-methoxyphenyl)-5-methyl-2-propylimidazole-4-carboxamide
Show/Hide
|
C30H41N5O2
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0373832
|
N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-1,2-dimethyl-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C28H36N4O
|
1
|
| 1 |
IC50 = 133 nM
|
|
|
|
CP0918739
|
N-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)-5-methoxy-2,6-dimethylpyrimidine-4-carboxamide hydrochloride
Show/Hide
|
C20H26Cl3N5O2
|
1
|
| 1 |
IC50 = 135 nM
|
|
|
|
CP0371721
|
N-(cyclohexylmethyl)-N-[3-[4-(4-fluorophenyl)piperazin-1-yl]propyl]quinoline-8-sulfonamide
Show/Hide
|
C29H37FN4O2S
|
1
|
| 1 |
IC50 = 135.8 nM
|
|
|
|
CP0401343
|
US8835436, Example 4
Show/Hide
|
C25H28Cl3N5O
|
1
|
| 1 |
IC50 = 136 nM
|
|
|
|
CP0373833
|
N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-1-ethyl-2-methyl-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C29H38N4O
|
1
|
| 1 |
IC50 = 139 nM
|
|
|
|
CP0891617
|
1-Cyclopentyl-N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C24H37Cl6N5O
|
1
|
| 1 |
IC50 = 139 nM
|
|
|
|
CP0922377
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-2-ethyl-5-methyl-1-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C26H35Cl6N5O
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0456760
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-2-ethyl-5-methyl-1-phenylimidazole-4-carboxamide
Show/Hide
|
C26H31Cl2N5O
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0857564
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-1-(2-methoxyphenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C28H39Cl2N5O2
|
1
|
| 1 |
IC50 = 146 nM
|
|
|
|
CP0858683
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-1-(4-methoxyphenyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C28H39Cl6N5O2
|
1
|
| 1 |
IC50 = 146 nM
|
|
|
|
CP0415700
|
N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-1-(2-methoxyphenyl)-2,5-dimethylimidazole-4-carboxamide
Show/Hide
|
C28H37N5O2
|
1
|
| 1 |
IC50 = 146 nM
|
|
|
|
CP0532670
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-1-(4-methoxyphenyl)-5-methyl-2-propylimidazole-4-carboxamide
Show/Hide
|
C28H35Cl2N5O2
|
1
|
| 1 |
IC50 = 146 nM
|
|
|
|
CP0544499
|
US8835436, Example 90
Show/Hide
|
C33H36BrCl2N5O
|
1
|
| 1 |
IC50 = 146 nM
|
|
|
|
CP0511603
|
N-(4-fluorophenyl)-6-[4-(4-fluorophenyl)piperazin-1-yl]-1-methylpyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
|
C22H21F2N7
|
1
|
| 1 |
IC50 = 148 nM
|
|
|
|
CP0664262
|
N-(2-(4-(2,3-dimethylphenyl)piperazin-1-yl)ethyl)-6-methyl-2-(methylthio)pyrimidine-4-carboxamide hydrochloride
Show/Hide
|
C21H30ClN5OS
|
1
|
| 1 |
IC50 = 148 nM
|
|
|
|
CP0846051
|
N-(4-fluorophenyl)-6-(4-(4-fluorophenyl)piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
|
C21H19F2N7
|
1
|
| 1 |
IC50 = 148 nM
|
|
|
|
CP0447406
|
N-[4-[4-(2,3-dimethylphenyl)piperazin-1-yl]butyl]-2-methyl-5-phenyl-1-propylpyrrole-3-carboxamide
Show/Hide
|
C31H42N4O
|
1
|
| 1 |
IC50 = 149 nM
|
|
|
|
CP0887876
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-2,5-dimethyl-1-(2-(trifluoromethyl)phenyl)-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C26H32Cl6F3N5O
|
1
|
| 1 |
IC50 = 155 nM
|
|
|
|
CP0428964
|
N-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]-1,2-dimethyl-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C25H28Cl2N4O
|
1
|
| 1 |
IC50 = 156 nM
|
|
|
|
CP0903799
|
N-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl)ethyl)-1-ethyl-2-methyl-5-phenyl-1H-pyrrole-3-carboxamide hydrochloride
Show/Hide
|
C25H29Cl3N4O
|
1
|
| 1 |
IC50 = 156 nM
|
|
|
|
CP0502602
|
N-(cyclohexylmethyl)-N-[3-(4-phenylpiperazin-1-yl)propyl]-4-(trifluoromethyl)benzenesulfonamide
Show/Hide
|
C27H36F3N3O2S
|
1
|
| 1 |
IC50 = 156.2 nM
|
|
|
|
CP0417852
|
N-[3-(4-methylpiperazin-1-yl)phenyl]-N-pentan-3-ylnaphthalene-2-sulfonamide
Show/Hide
|
C26H33N3O2S
|
1
|
| 1 |
IC50 = 159 nM
|
|
|
|
CP0894640
|
1-(3,5-Dimethoxyphenyl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C29H41Cl2N5O3
|
1
|
| 1 |
IC50 = 159 nM
|
|
|
|
CP0422518
|
1-(3,5-dimethoxyphenyl)-N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-2,5-dimethylimidazole-4-carboxamide
Show/Hide
|
C29H39N5O3
|
1
|
| 1 |
IC50 = 159 nM
|
|
|
|
CP0372469
|
N-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-1,2-dimethyl-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C26H31ClN4O
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0522007
|
N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-1-(4-fluorophenyl)-2-methyl-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C33H37FN4O
|
1
|
| 1 |
IC50 = 162 nM
|
|
|
|
CP0392991
|
4-ethyl-N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
Show/Hide
|
C15H24N2O2S
|
1
|
| 1 |
IC50 = 164 nM
|
|
|
|
CP0912346
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-cyclopentyl-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C25H39Cl4N5O2
|
1
|
| 1 |
IC50 = 166.3 nM
|
|
|
|
CP0381371
|
N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-1-benzofuran-3-carboxamide
Show/Hide
|
C20H15N3O3
|
1
|
| 1 |
IC50 = 167 nM
|
|
|
|
CP0522753
|
N-butan-2-yl-N-[3-(4-methylpiperazin-1-yl)phenyl]naphthalene-2-sulfonamide
Show/Hide
|
C25H31N3O2S
|
1
|
| 1 |
IC50 = 168 nM
|
|
|
|
CP0852995
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-2,5-dimethyl-1-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C27H37Cl2N5O
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0422033
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-1,2-dimethyl-5-pyridin-4-ylpyrrole-3-carboxamide
Show/Hide
|
C25H29Cl2N5O
|
1
|
| 1 |
IC50 = 175 nM
|
|
|
|
CP0439975
|
N,4-dimethyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
Show/Hide
|
C14H22N2O2S
|
1
|
| 1 |
IC50 = 179 nM
|
|
|
|
CP0541085
|
6-(hydroxymethyl)-N-[3-pyridin-3-yl-5-(trifluoromethoxy)phenyl]-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C22H18F3N3O3
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0923410
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-fluorophenyl)-5-methyl-2-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C32H38Cl2FN5O2
|
1
|
| 1 |
IC50 = 184.6 nM
|
|
|
|
CP0911229
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-1-(4-fluorophenyl)-5-methyl-2-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C30H34Cl6FN5O
|
1
|
| 1 |
IC50 = 185 nM
|
|
|
|
CP0914751
|
5-(4-Chlorophenyl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-2-methyl-1H-pyrrole-3-carboxamide hydrochloride
Show/Hide
|
C27H34Cl2N4O
|
1
|
| 1 |
IC50 = 189 nM
|
|
|
|
CP0858682
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-5-methyl-1-phenyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C27H37Cl6N5O
|
1
|
| 1 |
IC50 = 189 nM
|
|
|
|
CP0894534
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-1-(4-fluorophenyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C27H36Cl6FN5O
|
1
|
| 1 |
IC50 = 189 nM
|
|
|
|
CP0415720
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-5-methyl-1-phenyl-2-propylimidazole-4-carboxamide
Show/Hide
|
C27H33Cl2N5O
|
1
|
| 1 |
IC50 = 189 nM
|
|
|
|
CP0847152
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-1-(4-methoxyphenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C28H39Cl2N5O2
|
1
|
| 1 |
IC50 = 190.9 nM
|
|
|
|
CP0373828
|
N-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-1-ethyl-2-methyl-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C27H33ClN4O
|
1
|
| 1 |
IC50 = 192 nM
|
|
|
|
CP0918456
|
N-((R)-3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(2-fluorophenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C27H36Cl2FN5O2
|
1
|
| 1 |
IC50 = 193 nM
|
|
|
|
CP0385791
|
N-[(2R)-3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropyl]-1-(2-fluorophenyl)-2,5-dimethylimidazole-4-carboxamide
Show/Hide
|
C27H34FN5O2
|
1
|
| 1 |
IC50 = 193 nM
|
|
|
|
CP0857563
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-5-methyl-1,2-diphenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C32H39Cl2N5O
|
1
|
| 1 |
IC50 = 193.4 nM
|
|
|
|
CP0891570
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-2,5-dimethyl-1-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C22H35Cl6N5O
|
1
|
| 1 |
IC50 = 198 nM
|
|
|
|
CP0373567
|
N-[4-(4-phenylpiperazin-1-yl)butan-2-yl]naphthalene-2-sulfonamide
Show/Hide
|
C24H29N3O2S
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0430832
|
N-(cyclohexylmethyl)-4-methoxy-N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]benzenesulfonamide
Show/Hide
|
C28H41N3O4S
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0853001
|
1-(2-Chlorophenyl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C27H37Cl4N5O
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0403000
|
1-(2-chlorophenyl)-N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-2,5-dimethylimidazole-4-carboxamide
Show/Hide
|
C27H34ClN5O
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0847153
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-1-(4-methoxyphenyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C29H41Cl4N5O2
|
1
|
| 1 |
IC50 = 204 nM
|
|
|
|
CP0515714
|
N-[3-[4-(3-chloro-2-methylphenyl)piperazin-1-yl]propyl]-1-(4-methoxyphenyl)-5-methyl-2-propylimidazole-4-carboxamide
Show/Hide
|
C29H38ClN5O2
|
1
|
| 1 |
IC50 = 204 nM
|
|
|
|
CP0450054
|
US8835436, Example 100
Show/Hide
|
C28H37N5O3
|
1
|
| 1 |
IC50 = 207 nM
|
|
|
|
CP0373060
|
N-[3-[4-(3,4-dichlorophenyl)piperazin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
|
C23H25Cl2N3O2S
|
1
|
| 1 |
IC50 = 215 nM
|
|
|
|
CP0382795
|
1-benzyl-N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)-2-methyl-5-phenyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C32H34Cl2N4O
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0844939
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-2-methyl-5-(pyridin-2-yl)-1H-pyrrole-3-carboxamide dihydrochloride
Show/Hide
|
C24H31Cl6N5O
|
1
|
| 1 |
IC50 = 221 nM
|
|
|
|
CP0496219
|
N-[2-(dimethylamino)ethyl]-5-indol-1-ylthiophene-2-carboxamide
Show/Hide
|
C17H19N3OS
|
1
|
| 1 |
IC50 = 222 nM
|
|
|
|
CP0373834
|
N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-2-methyl-5-phenyl-1-propylpyrrole-3-carboxamide
Show/Hide
|
C30H40N4O
|
1
|
| 1 |
IC50 = 225 nM
|
|
|
|
CP0645882
|
N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)-6-isopropyl-2-methylpyrimidine-4-carboxamide Hydrochloride
Show/Hide
|
C22H30Cl3N5O
|
1
|
| 1 |
IC50 = 227 nM
|
|
|
|
CP0871165
|
(R)-N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-2,5-dimethyl-1-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C27H37Cl2N5O2
|
1
|
| 1 |
IC50 = 227 nM
|
|
|
|
CP0403437
|
N-[(2R)-3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropyl]-2,5-dimethyl-1-phenylimidazole-4-carboxamide
Show/Hide
|
C27H35N5O2
|
1
|
| 1 |
IC50 = 227 nM
|
|
|
|
CP0851845
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-1-(4-fluorophenyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C28H38Cl4FN5O
|
1
|
| 1 |
IC50 = 229 nM
|
|
|
|
CP0502357
|
1,2-Dimethyl-5-phenyl-N-(3-(4-(quinolin-8-yl)piperazin-1-yl)propyl)-1H-pyrrole-3-carboxamide
Show/Hide
|
C29H33N5O
|
1
|
| 1 |
IC50 = 233 nM
|
|
|
|
CP0930892
|
1-(4-Chlorophenyl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C27H37Cl4N5O
|
1
|
| 1 |
IC50 = 233 nM
|
|
|
|
CP0851846
|
1-(2-Chlorophenyl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C29H41Cl4N5O
|
1
|
| 1 |
IC50 = 235 nM
|
|
|
|
CP0917396
|
1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C31H43Cl2N5O3
|
1
|
| 1 |
IC50 = 237 nM
|
|
|
|
CP0847155
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-1-(4-fluorophenyl)-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C28H38Cl2FN5O
|
1
|
| 1 |
IC50 = 238 nM
|
|
|
|
CP0259093
|
N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
|
C24H29N3O3S
|
1
|
| 1 |
IC50 = 241 nM
|
|
|
|
CP0447906
|
6-N,6-N-diethyl-1-methyl-4-N-(2-methylphenyl)pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C17H22N6
|
1
|
| 1 |
IC50 = 242 nM
|
|
|
|
CP0848757
|
N6,N6-diethyl-N4-o-tolyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C16H20N6
|
1
|
| 1 |
IC50 = 242 nM
|
|
|
|
CP0545508
|
4-Chloro-N-isopropyl-N-[3-(4-methyl-piperazin-1-yl)-phenyl]-benzenesulfonamide
Show/Hide
|
C20H26ClN3O2S
|
1
|
| 1 |
IC50 = 243 nM
|
|
|
|
CP0916425
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-1,2-dimethyl-5-(pyridin-2-yl)-1H-pyrrole-3-carboxamide dihydrochloride
Show/Hide
|
C25H33Cl6N5O
|
1
|
| 1 |
IC50 = 267 nM
|
|
|
|
CP0857951
|
2-Benzyl-N-(4-methoxyphenyl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine-4-amine hydrochloride
Show/Hide
|
C22H25ClN4O
|
1
|
| 1 |
IC50 = 269 nM
|
|
|
|
CP0382791
|
N-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-2-methyl-5-phenyl-1-propylpyrrole-3-carboxamide
Show/Hide
|
C28H35ClN4O
|
1
|
| 1 |
IC50 = 273 nM
|
|
|
|
CP0429864
|
N-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-2-methyl-5-phenyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C25H29ClN4O
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0871157
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-1-(2-methoxyphenyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C30H43Cl2N5O2
|
1
|
| 1 |
IC50 = 283 nM
|
|
|
|
CP0851849
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C30H41Cl4N5O4
|
1
|
| 1 |
IC50 = 284 nM
|
|
|
|
CP0871152
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-5-methyl-1-phenyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C29H41Cl2N5O
|
1
|
| 1 |
IC50 = 286 nM
|
|
|
|
CP0852996
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-2-isopropyl-5-methyl-1-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C29H41Cl2N5O
|
1
|
| 1 |
IC50 = 290 nM
|
|
|
|
CP0408305
|
N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-5-methyl-1-phenyl-2-propan-2-ylimidazole-4-carboxamide
Show/Hide
|
C29H39N5O
|
1
|
| 1 |
IC50 = 290 nM
|
|
|
|
CP0528543
|
N-(cyclohexylmethyl)-4-fluoro-N-[3-(4-phenylpiperazin-1-yl)propyl]benzenesulfonamide
Show/Hide
|
C26H36FN3O2S
|
1
|
| 1 |
IC50 = 293.6 nM
|
|
|
|
CP0469851
|
1-benzyl-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-2-methyl-5-phenyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C34H40N4O
|
1
|
| 1 |
IC50 = 297 nM
|
|
|
|
CP0857559
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C29H39Cl6N5O3
|
1
|
| 1 |
IC50 = 297 nM
|
|
|
|
CP0469927
|
N-(cyclopropylmethyl)-N-[3-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
|
C28H32F3N3O2S
|
1
|
| 1 |
IC50 = 304 nM
|
|
|
|
CP0406101
|
N-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]-2-methyl-5-phenyl-1-propylpyrrole-3-carboxamide
Show/Hide
|
C27H32Cl2N4O
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0912349
|
1-(2-Chlorophenyl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C27H37Cl4N5O2
|
1
|
| 1 |
IC50 = 311 nM
|
|
|
|
CP0411036
|
US8835436, Example 89
Show/Hide
|
C31H30BrCl4N5O
|
1
|
| 1 |
IC50 = 319 nM
|
|
|
|
CP0514708
|
N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-1-benzofuran-3-sulfonamide
Show/Hide
|
C19H15N3O4S
|
1
|
| 1 |
IC50 = 321 nM
|
|
|
|
CP0508730
|
US8835436, Example 88
Show/Hide
|
C31H31BrCl3N5O
|
1
|
| 1 |
IC50 = 321 nM
|
|
|
|
CP0871162
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-methoxyphenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C27H37Cl4N5O3
|
1
|
| 1 |
IC50 = 323 nM
|
|
|
|
CP0871158
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-1-(4-fluorophenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C27H36Cl2FN5O
|
1
|
| 1 |
IC50 = 323.7 nM
|
|
|
|
CP0916526
|
N-(3-(4-(3,4-Dichlorophenyl)piperazin-1-yl)propyl)-2-methyl-5-phenyl-1-propyl-1H-pyrrole-3-carboxamide hydrochloride
Show/Hide
|
C28H35Cl3N4O
|
1
|
| 1 |
IC50 = 324 nM
|
|
|
|
CP0861747
|
4-(2-Benzyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-yl)thiomorpholine hydrochloride
Show/Hide
|
C19H25ClN4S
|
1
|
| 1 |
IC50 = 333 nM
|
|
|
|
CP0857950
|
N-(4-Fluorophenyl)-2-(4-methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine hydrochloride
Show/Hide
|
C19H26ClFN6
|
1
|
| 1 |
IC50 = 337 nM
|
|
|
|
CP0471449
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-2-methyl-1-(2-methylpropyl)-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C29H36Cl2N4O
|
1
|
| 1 |
IC50 = 342 nM
|
|
|
|
CP0430831
|
N-(cyclopropylmethyl)-N-[3-[4-(4-fluorophenyl)piperazin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
|
C27H32FN3O2S
|
1
|
| 1 |
IC50 = 343 nM
|
|
|
|
CP0372471
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-2-methyl-1-propyl-5-pyridin-3-ylpyrrole-3-carboxamide
Show/Hide
|
C27H33Cl2N5O
|
1
|
| 1 |
IC50 = 344 nM
|
|
|
|
CP0406098
|
N-[3-[4-(2,4-dichlorophenyl)piperazin-1-yl]propyl]-1,2-dimethyl-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C26H30Cl2N4O
|
1
|
| 1 |
IC50 = 349 nM
|
|
|
|
CP0871159
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-1-(4-chlorophenyl)-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C27H37Cl6N5O
|
1
|
| 1 |
IC50 = 367 nM
|
|
|
|
CP0894533
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-1-(2-methoxyphenyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C28H39Cl6N5O2
|
1
|
| 1 |
IC50 = 383 nM
|
|
|
|
CP0515345
|
US8835436, Example 132
Show/Hide
|
C26H34N6O
|
1
|
| 1 |
IC50 = 388 nM
|
|
|
|
CP0392059
|
N-[3-bromo-5-(trifluoromethoxy)phenyl]-5-methoxy-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C18H13BrF6N2O3
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
|
CP0917330
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-5-methyl-1-phenyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C28H39Cl4N5O2
|
1
|
| 1 |
IC50 = 398 nM
|
|
|
|
CP0472038
|
N-(4-fluorophenyl)-1-methyl-6-(4-phenylpiperazin-1-yl)pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
|
C22H22FN7
|
1
|
| 1 |
IC50 = 416 nM
|
|
|
|
CP0847879
|
N-(4-fluorophenyl)-6-(4-phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
|
C21H20FN7
|
1
|
| 1 |
IC50 = 416 nM
|
|
|
|
CP0452562
|
N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-2-methyl-5-phenyl-1-piperidin-1-ylpyrrole-3-carboxamide
Show/Hide
|
C32H43N5O
|
1
|
| 1 |
IC50 = 417 nM
|
|
|
|
CP0473460
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-2-methyl-1-propyl-5-pyridin-4-ylpyrrole-3-carboxamide
Show/Hide
|
C27H33Cl2N5O
|
1
|
| 1 |
IC50 = 420 nM
|
|
|
|
CP0493630
|
2-Methyl-5-phenyl-1-propyl-N-(3-(4-(quinolin-8-yl)piperazin-1-yl)propyl)-1H-pyrrole-3-carboxamide
Show/Hide
|
C31H37N5O
|
1
|
| 1 |
IC50 = 420 nM
|
|
|
|
CP0510352
|
N-[3-(4-methylpiperazin-1-yl)phenyl]-N-propan-2-ylnaphthalene-2-carboxamide
Show/Hide
|
C25H29N3O
|
1
|
| 1 |
IC50 = 420 nM
|
|
|
|
CP0470362
|
N-[2-(dimethylamino)ethyl]-1H-indole-2-carboxamide
Show/Hide
|
C13H17N3O
|
1
|
| 1 |
IC50 = 424 nM
|
|
|
|
CP0871028
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-methoxyphenyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C30H43Cl2N5O3
|
1
|
| 1 |
IC50 = 425 nM
|
|
|
|
CP0417821
|
N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropyl]-1-(4-methoxyphenyl)-5-methyl-2-propylimidazole-4-carboxamide
Show/Hide
|
C30H41N5O3
|
1
|
| 1 |
IC50 = 425 nM
|
|
|
|
CP0403039
|
US8835436, Example 106
Show/Hide
|
C29H39N5O2
|
1
|
| 1 |
IC50 = 438 nM
|
|
|
|
CP0382793
|
N-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-1-(4-fluorophenyl)-2-methyl-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C31H32ClFN4O
|
1
|
| 1 |
IC50 = 443 nM
|
|
|
|
CP0382792
|
N-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-2-methyl-5-phenyl-1-piperidin-1-ylpyrrole-3-carboxamide
Show/Hide
|
C30H38ClN5O
|
1
|
| 1 |
IC50 = 448 nM
|
|
|
|
CP0514205
|
N-[3-[4-(3-methoxyphenyl)piperazin-1-yl]propyl]-2-methyl-5-phenyl-1-propylpyrrole-3-carboxamide
Show/Hide
|
C29H38N4O2
|
1
|
| 1 |
IC50 = 452 nM
|
|
|
|
CP0853010
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(2-fluorophenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C25H32Cl6FN5O2
|
1
|
| 1 |
IC50 = 459 nM
|
|
|
|
CP0475677
|
N-[3-(4-methylpiperazin-1-yl)phenyl]-4-nitro-N-propan-2-ylbenzenesulfonamide
Show/Hide
|
C20H26N4O4S
|
1
|
| 1 |
IC50 = 462 nM
|
|
|
|
CP0379358
|
N,N-dimethyl-N'-[(E)-(1-naphthalen-2-ylsulfonyl-4-nitroindol-3-yl)methylideneamino]methanimidamide
Show/Hide
|
C22H19N5O4S
|
1
|
| 1 |
IC50 = 463 nM
|
|
|
|
CP0403439
|
US8835436, Example 133
Show/Hide
|
C30H31Cl2N5O3
|
1
|
| 1 |
IC50 = 463 nM
|
|
|
|
CP0244731
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-1-(4-fluorophenyl)-2-methyl-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C31H31Cl2FN4O
|
1
|
| 1 |
IC50 = 466 nM
|
|
|
|
CP0398639
|
N-(3-iodophenyl)-N-propan-2-ylnaphthalene-2-sulfonamide
Show/Hide
|
C19H18INO2S
|
1
|
| 1 |
IC50 = 467 nM
|
|
|
|
CP0427524
|
N-methyl-N-(1-methylpiperidin-4-yl)-4-propylbenzenesulfonamide
Show/Hide
|
C16H26N2O2S
|
1
|
| 1 |
IC50 = 471 nM
|
|
|
|
CP0871156
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-1-(2-methoxyphenyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C29H41Cl4N5O2
|
1
|
| 1 |
IC50 = 473 nM
|
|
|
|
CP0493714
|
1-methyl-N-(6-(2-methylpyridin-3-yloxy)pyridin-3-yl)-1H-indole-3-carboxamide
Show/Hide
|
C21H18N4O2
|
1
|
| 1 |
IC50 = 474 nM
|
|
|
|
CP0893205
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(2-methoxyphenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C27H37Cl4N5O3
|
1
|
| 1 |
IC50 = 476 nM
|
|
|
|
CP0426880
|
N-(cyclopropylmethyl)-N-[3-(4-phenylpiperazin-1-yl)propyl]naphthalene-2-sulfonamide
Show/Hide
|
C27H33N3O2S
|
1
|
| 1 |
IC50 = 479 nM
|
|
|
|
CP0871166
|
(R)-N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-fluorophenyl)-5-methyl-2-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C31H36Cl4FN5O2
|
1
|
| 1 |
IC50 = 479 nM
|
|
|
|
CP0379360
|
N,N-dimethyl-N'-[(E)-[1-(4-methylphenyl)sulfonyl-4-nitroindol-3-yl]methylideneamino]methanimidamide
Show/Hide
|
C19H19N5O4S
|
1
|
| 1 |
IC50 = 480 nM
|
|
|
|
CP0406099
|
N-[3-[4-(4-fluorophenyl)piperazin-1-yl]propyl]-1,2-dimethyl-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C26H31FN4O
|
1
|
| 1 |
IC50 = 493 nM
|
|
|
|
CP0418193
|
2-(4-(4-(4-fluorophenylamino)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-6-yl)piperazin-1-yl)ethanol
Show/Hide
|
C18H22FN7O
|
1
|
| 1 |
IC50 = 494 nM
|
|
|
|
CP0860117
|
2-tert-butyl-N-(2-(4-(2,3-dimethylphenyl)piperazin-1-yl)ethyl)-6-methylpyrimidine-4-carboxamide hydrochloride
Show/Hide
|
C24H36ClN5O
|
1
|
| 1 |
IC50 = 494 nM
|
|
|
|
CP0847878
|
2-(4-(4-(4-fluorophenylamino)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)piperazin-1-yl)ethanol
Show/Hide
|
C17H20FN7O
|
1
|
| 1 |
IC50 = 494 nM
|
|
|
|
CP0401604
|
N-methyl-N-(1-methylpiperidin-4-yl)-4-phenylbenzenesulfonamide
Show/Hide
|
C19H24N2O2S
|
1
|
| 1 |
IC50 = 523 nM
|
|
|
|
CP0851847
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-5-methyl-1,2-diphenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C32H39Cl2N5O2
|
1
|
| 1 |
IC50 = 525 nM
|
|
|
|
CP0389324
|
N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropyl]-5-methyl-1,2-diphenylimidazole-4-carboxamide
Show/Hide
|
C32H37N5O2
|
1
|
| 1 |
IC50 = 525 nM
|
|
|
|
CP0853008
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-methoxyphenyl)-5-methyl-2-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C32H39Cl4N5O3
|
1
|
| 1 |
IC50 = 526 nM
|
|
|
|
CP0875068
|
(S)-N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-fluorophenyl)-5-methyl-2-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C31H36Cl4FN5O2
|
1
|
| 1 |
IC50 = 534 nM
|
|
|
|
CP0420202
|
N-[(2S)-3-[4-(3-chloro-2-methylphenyl)piperazin-1-yl]-2-hydroxypropyl]-1-(4-fluorophenyl)-5-methyl-2-phenylimidazole-4-carboxamide
Show/Hide
|
C31H33ClFN5O2
|
1
|
| 1 |
IC50 = 534 nM
|
|
|
|
CP0847163
|
1-(3-Chlorophenyl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C27H37Cl4N5O2
|
1
|
| 1 |
IC50 = 535.2 nM
|
|
|
|
CP0497111
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butan-2-yl]naphthalene-2-sulfonamide
Show/Hide
|
C25H31N3O3S
|
1
|
| 1 |
IC50 = 539 nM
|
|
|
|
CP0504210
|
N-(6-phenoxypyridin-3-yl)-1H-indole-3-carboxamide
Show/Hide
|
C20H15N3O2
|
1
|
| 1 |
IC50 = 542 nM
|
|
|
|
CP0539551
|
US8835436, Example 109
Show/Hide
|
C28H37N5O2
|
1
|
| 1 |
IC50 = 542 nM
|
|
|
|
CP0847158
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-methoxyphenyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C28H39Cl6N5O3
|
1
|
| 1 |
IC50 = 544 nM
|
|
|
|
CP0561515
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]-2-hydroxypropyl]-1-(4-methoxyphenyl)-5-methyl-2-propylimidazole-4-carboxamide
Show/Hide
|
C28H35Cl2N5O3
|
1
|
| 1 |
IC50 = 544 nM
|
|
|
|
CP0853006
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-methoxyphenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C28H39Cl2N5O3
|
1
|
| 1 |
IC50 = 546.4 nM
|
|
|
|
CP0373571
|
N-(cyclopropylmethyl)-N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
|
C28H35N3O3S
|
1
|
| 1 |
IC50 = 549 nM
|
|
|
|
CP0871027
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-2-hydroxypropyl)-5-methyl-1,2-diphenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C30H35Cl6N5O2
|
1
|
| 1 |
IC50 = 551 nM
|
|
|
|
CP0402819
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]-2-hydroxypropyl]-5-methyl-1,2-diphenylimidazole-4-carboxamide
Show/Hide
|
C30H31Cl2N5O2
|
1
|
| 1 |
IC50 = 551 nM
|
|
|
|
CP0894623
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(3-chlorophenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C26H35Cl6N5O2
|
1
|
| 1 |
IC50 = 556.5 nM
|
|
|
|
CP0373410
|
N-(cyclopropylmethyl)-N-[3-(4-phenylpiperazin-1-yl)propyl]-4-(trifluoromethyl)benzenesulfonamide
Show/Hide
|
C24H30F3N3O2S
|
1
|
| 1 |
IC50 = 565 nM
|
|
|
|
CP0505205
|
N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-1-benzothiophene-3-sulfonamide
Show/Hide
|
C19H15N3O3S2
|
1
|
| 1 |
IC50 = 572 nM
|
|
|
|
CP0645881
|
6-tert-butyl-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-2-methylpyrimidine-4-carboxamide Hydrochloride
Show/Hide
|
C25H38ClN5O
|
1
|
| 1 |
IC50 = 575 nM
|
|
|
|
CP0399040
|
N,3-dimethyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
Show/Hide
|
C14H22N2O2S
|
1
|
| 1 |
IC50 = 579 nM
|
|
|
|
CP0459191
|
methyl 4-oxo-2-piperidin-4-yl-3H-pyrazolo[1,5-a][1,3,5]triazine-8-carboxylate
Show/Hide
|
C12H15N5O3
|
1
|
| 1 |
IC50 = 589 nM
|
|
|
|
CP0847166
|
1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-5-methyl-2-propyl-1Himidazole-4-carboxamide dihydrochloride
Show/Hide
|
C31H43Cl2N5O4
|
1
|
| 1 |
IC50 = 593 nM
|
|
|
|
CP0538189
|
N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropyl]-2,5-dimethyl-1-(2-methylpropyl)imidazole-4-carboxamide
Show/Hide
|
C25H39N5O2
|
1
|
| 1 |
IC50 = 595 nM
|
|
|
|
CP0853004
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-isobutyl-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C25H41Cl2N5O2
|
1
|
| 1 |
IC50 = 595.4 nM
|
|
|
|
CP0074514
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-2-methyl-5-phenyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C25H28Cl2N4O
|
1
|
| 1 |
IC50 = 599 nM
|
|
|
|
CP0487924
|
6-fluoro-N-[3-pyridin-3-yl-5-(trifluoromethoxy)phenyl]-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C21H15F4N3O2
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0439977
|
3-chloro-N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
Show/Hide
|
C13H19ClN2O2S
|
1
|
| 1 |
IC50 = 603 nM
|
|
|
|
CP0894626
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-5-methyl-1-phenyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C28H39Cl4N5O
|
1
|
| 1 |
IC50 = 604 nM
|
|
|
|
CP0871163
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-methoxyphenyl)-5-methyl-2-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C33H41Cl2N5O3
|
1
|
| 1 |
IC50 = 609 nM
|
|
|
|
CP0847165
|
1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-2,5-dimethyl-1Himidazole-4-carboxamide dihydrochloride
Show/Hide
|
C29H39Cl2N5O4
|
1
|
| 1 |
IC50 = 609.6 nM
|
|
|
|
CP0391852
|
2-(2,4-Dichloro-phenoxy)-N-[4-methyl-2-(4-methyl-piperazin-1-yl)-quinolin-6-yl]-acetamide
Show/Hide
|
C23H24Cl2N4O2
|
1
|
| 1 |
IC50 = 610 nM
|
|
|
|
CP0817944
|
N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)-2,6-dimethylpyrimidine-4-carboxamide Hydrochloride
Show/Hide
|
C20H26Cl3N5O
|
1
|
| 1 |
IC50 = 610 nM
|
|
|
|
CP0382794
|
N-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-1-(cyclohexylmethyl)-2-methyl-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C32H41ClN4O
|
1
|
| 1 |
IC50 = 611 nM
|
|
|
|
CP0406102
|
N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-2-methyl-5-phenyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C27H34N4O
|
1
|
| 1 |
IC50 = 615 nM
|
|
|
|
CP0916527
|
2-Methyl-5-phenyl-1-propyl-N-(3-(4-(3-(trifluoromethyl)-phenyl)piperazin-1-yl)propyl)-1H-pyrrole-3-carboxamide hydrochloride
Show/Hide
|
C29H36ClF3N4O
|
1
|
| 1 |
IC50 = 619 nM
|
|
|
|
CP0039374
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-2-methyl-5-phenyl-1-propylpyrrole-3-carboxamide
Show/Hide
|
C28H34Cl2N4O
|
1
|
| 1 |
IC50 = 628 nM
|
|
|
|
CP0470721
|
N-[3-[4-(2-bromophenyl)piperazin-1-yl]propyl]-1,2-dimethyl-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C26H31BrN4O
|
1
|
| 1 |
IC50 = 633 nM
|
|
|
|
CP0493628
|
N-[3-[4-(3-bromophenyl)piperazin-1-yl]propyl]-2-methyl-5-phenyl-1-propylpyrrole-3-carboxamide
Show/Hide
|
C28H35BrN4O
|
1
|
| 1 |
IC50 = 633 nM
|
|
|
|
CP0420463
|
US8835436, Example 121
Show/Hide
|
C28H37N5O2
|
1
|
| 1 |
IC50 = 635 nM
|
|
|
|
CP0429866
|
1-(cyclohexylmethyl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-2-methyl-5-phenyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C34H46N4O
|
1
|
| 1 |
IC50 = 638 nM
|
|
|
|
CP0916426
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-2-methyl-1-propyl-5-(pyridin-2-yl)-1H-pyrrole-3-carboxamide dihydrochloride
Show/Hide
|
C27H37Cl6N5O
|
1
|
| 1 |
IC50 = 639 nM
|
|
|
|
CP0523815
|
1,2-Dimethyl-N-(3-(4-(2-methylquinolin-8-yl)piperazin-1-yl)propyl)-5-phenyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C30H35N5O
|
1
|
| 1 |
IC50 = 653 nM
|
|
|
|
CP0847160
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-fluorophenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C27H36Cl2FN5O2
|
1
|
| 1 |
IC50 = 653.7 nM
|
|
|
|
CP0875066
|
1-(4-Chlorophenyl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C29H41Cl4N5O2
|
1
|
| 1 |
IC50 = 661 nM
|
|
|
|
CP0389365
|
US8835436, Example 111
Show/Hide
|
C28H36ClN5O2
|
1
|
| 1 |
IC50 = 661 nM
|
|
|
|
CP0871164
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C28H37Cl4N5O4
|
1
|
| 1 |
IC50 = 663 nM
|
|
|
|
CP0492831
|
N-(cyclopropylmethyl)-4-methoxy-N-[3-(4-phenylpiperazin-1-yl)propyl]benzenesulfonamide
Show/Hide
|
C24H33N3O3S
|
1
|
| 1 |
IC50 = 691 nM
|
|
|
|
CP0371722
|
N-(cyclopropylmethyl)-N-[3-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]propyl]quinoline-8-sulfonamide
Show/Hide
|
C27H31F3N4O2S
|
1
|
| 1 |
IC50 = 694 nM
|
|
|
|
CP0450109
|
US8835436, Example 148
Show/Hide
|
C28H37N5O2
|
1
|
| 1 |
IC50 = 705 nM
|
|
|
|
CP0452722
|
N-(cyclopropylmethyl)-N-[3-[4-(4-fluorophenyl)piperazin-1-yl]propyl]-4-methoxybenzenesulfonamide
Show/Hide
|
C24H32FN3O3S
|
1
|
| 1 |
IC50 = 723 nM
|
|
|
|
CP0429728
|
US8835436, Example 141
Show/Hide
|
C26H30Cl3N5O2
|
1
|
| 1 |
IC50 = 737 nM
|
|
|
|
CP0853002
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-5-methyl-1,2-diphenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C31H37Cl4N5O2
|
1
|
| 1 |
IC50 = 739 nM
|
|
|
|
CP0452116
|
4-iodo-N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
Show/Hide
|
C13H19IN2O2S
|
1
|
| 1 |
IC50 = 766 nM
|
|
|
|
CP0409389
|
2-(2,4-Dichloro-phenoxy)-N-{4-methyl-2-[methyl-(2-methylamino-ethyl)-amino]-quinolin-6-yl}-acetamide
Show/Hide
|
C22H24Cl2N4O2
|
1
|
| 1 |
IC50 = 770 nM
|
|
|
|
CP0871029
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(2-fluorophenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C26H34Cl4FN5O2
|
1
|
| 1 |
IC50 = 774 nM
|
|
|
|
CP0919957
|
N-(4-Fluorophenyl)-7-methyl-2-(4-methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine hydrochloride
Show/Hide
|
C20H28ClFN6
|
1
|
| 1 |
IC50 = 779 nM
|
|
|
|
CP0513542
|
N-[3-[4-(2,3-dimethoxyphenyl)piperazin-1-yl]propyl]-1,2-dimethyl-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C28H36N4O3
|
1
|
| 1 |
IC50 = 782 nM
|
|
|
|
CP0074515
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-2-methyl-5-phenyl-1-piperidin-1-ylpyrrole-3-carboxamide
Show/Hide
|
C30H37Cl2N5O
|
1
|
| 1 |
IC50 = 795 nM
|
|
|
|
CP0431769
|
US8835436, Example 98
Show/Hide
|
C23H34ClN5O2
|
1
|
| 1 |
IC50 = 815 nM
|
|
|
|
CP0502772
|
6-(4-benzylpiperazin-1-yl)-N-(4-fluorophenyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
|
C23H24FN7
|
1
|
| 1 |
IC50 = 836 nM
|
|
|
|
CP0880357
|
6-(4-benzylpiperazin-1-yl)-N-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
|
C22H22FN7
|
1
|
| 1 |
IC50 = 836 nM
|
|
|
|
CP0430833
|
N-(cyclohexylmethyl)-N-[3-(4-phenylpiperazin-1-yl)propyl]quinoline-8-sulfonamide
Show/Hide
|
C29H38N4O2S
|
1
|
| 1 |
IC50 = 842.7 nM
|
|
|
|
CP0847164
|
1-(4-Chlorophenyl)-N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)-2-hydroxypropyl)-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C26H35Cl8N5O2
|
1
|
| 1 |
IC50 = 855.9 nM
|
|
|
|
CP0034944
|
(E)-N-{2-[(2-Dimethylamino-ethyl)-methyl-amino]-4-methyl-quinolin-6-yl}-3-(4-trifluoromethoxy-phenyl)-acrylamide
Show/Hide
|
C25H27F3N4O2
|
1
|
| 1 |
IC50 = 900 nM
|
|
|
|
CP0371728
|
N-[4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]butan-2-yl]naphthalene-2-sulfonamide
Show/Hide
|
C25H28F3N3O2S
|
1
|
| 1 |
IC50 = 942 nM
|
|
|
|
CP0917398
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-chlorophenyl)-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C27H37Cl6N5O2
|
1
|
| 1 |
IC50 = 953 nM
|
|
|
|
CP0473457
|
N-[3-[4-(2,3-dimethoxyphenyl)piperazin-1-yl]propyl]-2-methyl-5-phenyl-1-propylpyrrole-3-carboxamide
Show/Hide
|
C30H40N4O3
|
1
|
| 1 |
IC50 = 977 nM
|
|
|
|
CP0496205
|
4-N-(4-chlorophenyl)-6-N,6-N-diethyl-1-methylpyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C16H19ClN6
|
1
|
| 1 |
IC50 = 991 nM
|
|
|
|
CP0857942
|
N4-(4-chlorophenyl)-N6,N6-diethyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C15H17ClN6
|
1
|
| 1 |
IC50 = 991 nM
|
|
|
|
CP0871031
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-fluorophenyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C29H40Cl2FN5O2
|
1
|
| 1 |
IC50 = 1001 nM
|
|
|
|
CP0473458
|
N-[3-[4-(2,5-difluorophenyl)piperazin-1-yl]propyl]-2-methyl-5-phenyl-1-propylpyrrole-3-carboxamide
Show/Hide
|
C28H34F2N4O
|
1
|
| 1 |
IC50 = 1006 nM
|
|
|
|
CP0399042
|
N-methyl-N-(1-methylpiperidin-4-yl)-4-propan-2-ylbenzenesulfonamide
Show/Hide
|
C16H26N2O2S
|
1
|
| 1 |
IC50 = 1010 nM
|
|
|
|
CP0497501
|
5-tert-butyl-N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-1,2-dimethylpyrrole-3-carboxamide
Show/Hide
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C24H34Cl2N4O
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1
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| 1 |
IC50 = 1021 nM
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CP0875067
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N-((S)-3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(2-fluorophenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C27H36Cl2FN5O2
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1
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| 1 |
IC50 = 1031 nM
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CP0420502
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N-[(2S)-3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropyl]-1-(2-fluorophenyl)-2,5-dimethylimidazole-4-carboxamide
Show/Hide
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C27H34FN5O2
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1
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| 1 |
IC50 = 1031 nM
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CP0496121
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1-(cyclohexylmethyl)-N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)-2-methyl-5-phenyl-1H-pyrrole-3-carboxamide
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C32H40Cl2N4O
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1
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| 1 |
IC50 = 1034 nM
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CP0463951
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N-(cyclopropylmethyl)-4-methoxy-N-[3-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]propyl]benzenesulfonamide
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C25H32F3N3O3S
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1
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| 1 |
IC50 = 1034 nM
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CP0379359
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N'-[(E)-[1-(4-methoxyphenyl)sulfonyl-4-nitroindol-3-yl]methylideneamino]-N,N-dimethylmethanimidamide
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C19H19N5O5S
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1
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| 1 |
IC50 = 1040 nM
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CP0503176
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4-tert-butyl-N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
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C17H28N2O2S
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1
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| 1 |
IC50 = 1055 nM
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CP0471916
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6-(4-(4-fluorophenyl)piperazin-1-yl)-N-(3-methoxyphenyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
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C23H24FN7O
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1
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| 1 |
IC50 = 1085 nM
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CP0857944
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6-(4-(4-fluorophenyl)piperazin-1-yl)-N-(3-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
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C22H22FN7O
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1
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| 1 |
IC50 = 1085 nM
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CP0378080
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(E)-N-(4-Methyl-2-piperazin-1-yl-quinolin-6-yl)-3-(4-trifluoromethoxy-phenyl)-acrylamide
Show/Hide
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C24H23F3N4O2
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1
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| 1 |
IC50 = 1100 nM
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CP0406103
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5-tert-Butyl-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-1,2-dimethyl-1H-pyrrole-3-carboxamide
Show/Hide
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C26H40N4O
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1
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| 1 |
IC50 = 1145 nM
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CP0845009
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N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-6-methyl-2-(methylthio)pyrimidine-4-carboxamide hydrochloride
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C22H32ClN5OS
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1
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| 1 |
IC50 = 1170 nM
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CP0860115
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2-cyclopropyl-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-6-methylpyrimidine-4-carboxamide hydrochloride
Show/Hide
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C24H34ClN5O
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1
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| 1 |
IC50 = 1178 nM
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CP0450630
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6-(4-(4-fluorophenyl)piperazin-1-yl)-N-(4-methoxyphenyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
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C23H24FN7O
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1
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| 1 |
IC50 = 1179 nM
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CP0919958
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6-(4-(4-fluorophenyl)piperazin-1-yl)-N-(4-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
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C22H22FN7O
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1
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| 1 |
IC50 = 1179 nM
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CP0853009
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1-(3,4-Dimethoxyphenyl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C29H41Cl2N5O4
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1
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| 1 |
IC50 = 1184 nM
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CP0454934
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2-chloro-N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
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C13H19ClN2O2S
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1
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| 1 |
IC50 = 1195 nM
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CP0401642
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4-chloro-N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
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C13H19ClN2O2S
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1
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| 1 |
IC50 = 1208 nM
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CP0499474
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N-[3-pyridin-3-yl-5-(trifluoromethoxy)phenyl]-2,3-dihydroindole-1-carboxamide
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C21H16F3N3O2
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1
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| 1 |
IC50 = 1250 nM
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CP0857943
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4-(furan-2-ylmethoxy)-2-(4-methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-pyrimido[5,4-d]azepine hydrochloride
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C18H26ClN5O2
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1
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| 1 |
IC50 = 1262 nM
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CP0845008
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N-(2-(4-(2,3-dimethylphenyl)piperazin-1-yl)ethyl)-5-methoxy-2,6-dimethylpyrimidine-4-carboxamide hydrochloride
Show/Hide
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C22H32ClN5O2
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1
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| 1 |
IC50 = 1266 nM
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CP0373836
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N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-2-methyl-1-(2-methylpropyl)-5-phenylpyrrole-3-carboxamide
Show/Hide
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C31H42N4O
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1
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| 1 |
IC50 = 1298 nM
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CP0479998
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N-(4-fluorophenyl)-1-methyl-6-piperidin-1-ylpyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
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C17H19FN6
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1
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| 1 |
IC50 = 1300 nM
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CP0864840
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N-(4-fluorophenyl)-6-(piperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
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C16H17FN6
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1
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| 1 |
IC50 = 1300 nM
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CP0459682
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4-Methoxy-N-{3-[4-(m-trifluoromethylphenyl)-piperazin-1-yl]-1-methyl-propyl}-benzenesulfonamide
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C22H28F3N3O3S
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1
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| 1 |
IC50 = 1349 nM
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CP0851848
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N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-methoxyphenyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C29H41Cl4N5O3
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1
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| 1 |
IC50 = 1365 nM
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CP0775801
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5-((1H-1,2,4-Triazol-1-yl)methyl)-N-(3-(4-(3-chloro-2-methylphenyl)piperazin-1-yl)propyl)-1,2-diphenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C33H38Cl4N8O
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1
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| 1 |
IC50 = 1368 nM
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CP0861034
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5-tert-Butyl-N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)-propyl)-2-methyl-1H-pyrrole-3-carboxamide hydrochloride
Show/Hide
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C23H33Cl3N4O
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1
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| 1 |
IC50 = 1392 nM
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CP0513545
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N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-2-methyl-5-phenyl-1-propylpyrrole-3-carboxamide
Show/Hide
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C29H38N4O2
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1
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| 1 |
IC50 = 1408 nM
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CP0373830
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1-benzyl-N-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)-2-methyl-5-phenyl-1H-pyrrole-3-carboxamide
Show/Hide
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C32H35ClN4O
|
1
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| 1 |
IC50 = 1436 nM
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CP0847159
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N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-fluorophenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C26H34Cl4FN5O2
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1
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| 1 |
IC50 = 1454 nM
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CP0447686
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N-(cyclopropylmethyl)-N-[3-(4-phenylpiperazin-1-yl)propyl]naphthalene-1-sulfonamide
Show/Hide
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C27H33N3O2S
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1
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| 1 |
IC50 = 1459 nM
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CP0450631
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N-(4-fluorophenyl)-1-methyl-6-(4-methylpiperidin-1-yl)pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
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C18H21FN6
|
1
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| 1 |
IC50 = 1500 nM
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CP0856418
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N-(4-fluorophenyl)-6-(4-methylpiperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
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C17H19FN6
|
1
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| 1 |
IC50 = 1500 nM
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CP0751540
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N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-5-methyl-1,2-diphenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C31H37Cl4N5O
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1
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| 1 |
IC50 = 1506 nM
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CP0919599
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N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-fluorophenyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C27H36Cl6FN5O2
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1
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| 1 |
IC50 = 1509 nM
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CP0845010
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N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-6-isopropyl-2-methylpyrimidine-4-carboxamide Hydrochloride
Show/Hide
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C24H36ClN5O
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1
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| 1 |
IC50 = 1548 nM
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CP0485074
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(E)-N-(2-[1,4]Diazepan-1-yl-4-methyl-quinolin-6-yl)-3-(4-trifluoromethoxy-phenyl)-acrylamide
Show/Hide
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C25H25F3N4O2
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1
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| 1 |
IC50 = 1600 nM
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CP0373829
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N-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-2-methyl-1-(2-methylpropyl)-5-phenylpyrrole-3-carboxamide
Show/Hide
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C29H37ClN4O
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1
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| 1 |
IC50 = 1602 nM
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CP0487861
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N-[4-(4-methylpiperazin-1-yl)phenyl]-N-propan-2-ylnaphthalene-2-sulfonamide
Show/Hide
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C24H29N3O2S
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1
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| 1 |
IC50 = 1715 nM
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CP0470610
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N-(4-fluorophenyl)-6-[4-(2-methoxyphenyl)piperazin-1-yl]-1-methylpyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
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C23H24FN7O
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1
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| 1 |
IC50 = 1725 nM
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CP0856419
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N-(4-fluorophenyl)-6-(4-(2-methoxyphenyl)piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
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C22H22FN7O
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1
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| 1 |
IC50 = 1725 nM
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CP0847168
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(S)-N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-2,5-dimethyl-1-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C27H37Cl2N5O2
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1
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| 1 |
IC50 = 1779 nM
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CP0472314
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N-[(2S)-3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropyl]-2,5-dimethyl-1-phenylimidazole-4-carboxamide
Show/Hide
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C27H35N5O2
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1
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| 1 |
IC50 = 1779 nM
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CP0427521
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N,2-dimethyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
Show/Hide
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C14H22N2O2S
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1
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| 1 |
IC50 = 1820 nM
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CP0401605
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4-methoxy-N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
Show/Hide
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C14H22N2O3S
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1
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| 1 |
IC50 = 1863 nM
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CP0496232
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N,3,4-trimethyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
Show/Hide
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C15H24N2O2S
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1
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| 1 |
IC50 = 1940 nM
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CP0415113
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N-(cyclopropylmethyl)-4-nitro-N-[3-(4-phenylpiperazin-1-yl)propyl]benzenesulfonamide
Show/Hide
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C23H30N4O4S
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1
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| 1 |
IC50 = 1943 nM
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CP0415115
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N-(cyclopropylmethyl)-4-methoxy-N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]benzenesulfonamide
Show/Hide
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C25H35N3O4S
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1
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| 1 |
IC50 = 1976 nM
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CP0507696
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N-(cyclopropylmethyl)-4-fluoro-N-[3-(4-phenylpiperazin-1-yl)propyl]benzenesulfonamide
Show/Hide
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C23H30FN3O2S
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1
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| 1 |
IC50 = 1981 nM
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CP0374011
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N-[2-(dimethylamino)ethyl]-N-(4-fluoro-1,3-benzothiazol-2-yl)acetamide
Show/Hide
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C13H16FN3OS
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1
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| 1 |
IC50 = 1999 nM
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CP0378079
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2-(2,4-Dichloro-phenoxy)-N-(4-methyl-2-piperazin-1-yl-quinolin-6-yl)-acetamide
Show/Hide
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C22H22Cl2N4O2
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1
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| 1 |
IC50 = 2000 nM
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CP0913240
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N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-5-methoxy-2,6-dimethylpyrimidine-4-carboxamide hydrochloride
Show/Hide
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C23H34ClN5O2
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1
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| 1 |
IC50 = 2049 nM
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CP0384559
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ethyl 4-(4-methylpiperazin-1-yl)-[1,2]oxazolo[5,4-d]pyrimidine-3-carboxylate
Show/Hide
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C13H17N5O3
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1
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| 1 |
IC50 = 2052 nM
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CP0384565
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N-(4-fluorophenyl)-1-methyl-6-morpholin-4-ylpyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
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C16H17FN6O
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1
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| 1 |
IC50 = 2071 nM
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CP0876517
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N-(4-fluorophenyl)-6-morpholino-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
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C15H15FN6O
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1
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| 1 |
IC50 = 2071 nM
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CP0373566
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N-(cyclopropylmethyl)-N-[3-(4-phenylpiperazin-1-yl)propyl]quinoline-8-sulfonamide
Show/Hide
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C26H32N4O2S
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1
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| 1 |
IC50 = 2159 nM
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CP0903877
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N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-1-isobutyl-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C24H39Cl4N5O
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1
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| 1 |
IC50 = 2221 nM
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CP0418377
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N-[3-[4-(3-chloro-2-methylphenyl)piperazin-1-yl]propyl]-2,5-dimethyl-1-(2-methylpropyl)imidazole-4-carboxamide
Show/Hide
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C24H36ClN5O
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1
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| 1 |
IC50 = 2221 nM
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CP0497500
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5-tert-Butyl-N-(2-(4-(2,3-dimethylphenyl)piperazin-1-yl)ethyl)-1,2-dimethyl-1H-pyrrole-3-carboxamide
Show/Hide
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C25H38N4O
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1
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| 1 |
IC50 = 2227 nM
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CP0917395
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N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-1-(4-fluorophenyl)-5-methyl-2-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C31H36Cl4FN5O
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1
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| 1 |
IC50 = 2239 nM
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CP0504234
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N-[6-(6-methylpyridin-3-yl)oxypyridin-3-yl]-1H-indole-3-carboxamide
Show/Hide
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C20H16N4O2
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1
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| 1 |
IC50 = 2253 nM
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CP0504041
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3-fluoro-N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
Show/Hide
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C13H19FN2O2S
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1
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| 1 |
IC50 = 2422 nM
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CP0401603
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4-fluoro-N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
Show/Hide
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C13H19FN2O2S
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1
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| 1 |
IC50 = 2534 nM
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CP0384567
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6-N-benzyl-4-N-(4-fluorophenyl)-1-methylpyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C19H17FN6
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1
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| 1 |
IC50 = 2588 nM
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CP0912131
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N6-benzyl-N4-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C18H15FN6
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1
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| 1 |
IC50 = 2588 nM
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CP0851117
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2-tert-butyl-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-6-methylpyrimidine-4-carboxamide hydrochloride
Show/Hide
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C25H38ClN5O
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1
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| 1 |
IC50 = 2688 nM
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CP0418206
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N-[2-(dimethylamino)ethyl]-N-([1,3]dioxolo[4,5-f][1,3]benzothiazol-6-yl)acetamide
Show/Hide
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C14H17N3O3S
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1
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| 1 |
IC50 = 2732 nM
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CP0847157
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rac-N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-2,5-dimethyl-1-phenyl-1H-imidazole-4-carboxamide dihydrochloride dihydrochloride
Show/Hide
|
C27H37Cl2N5O2
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1
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| 1 |
IC50 = 2741 nM
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CP0856415
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N-(3-Methoxyphenyl)-2-(4-methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine hydrochloride
Show/Hide
|
C20H29ClN6O
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1
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| 1 |
IC50 = 2852 nM
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CP0470363
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6-N,6-N-diethyl-4-N-(4-fluorophenyl)-1-methylpyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C16H19FN6
|
1
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| 1 |
IC50 = 3306 nM
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CP0856417
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N6,N6-diethyl-N4-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C15H17FN6
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1
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| 1 |
IC50 = 3306 nM
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CP0385575
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6-(3,5-dimethylpiperidin-1-yl)-N-(4-fluorophenyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
|
C19H23FN6
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1
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| 1 |
IC50 = 3817 nM
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CP0864805
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6-(3,5-dimethylpiperidin-1-yl)-N-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
|
C18H21FN6
|
1
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| 1 |
IC50 = 3817 nM
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CP0725663
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1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C29H39Cl2N5O3
|
1
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| 1 |
IC50 = 3996 nM
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CP0391850
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N-[2-[3-(dimethylamino)propylamino]-4-methylquinolin-6-yl]-2-[4-(trifluoromethoxy)phenoxy]acetamide
Show/Hide
|
C24H27F3N4O3
|
1
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| 1 |
IC50 = 4000 nM
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CP0496220
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4-N-(4-fluorophenyl)-6-N,6-N,1-trimethylpyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C14H15FN6
|
1
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| 1 |
IC50 = 4027 nM
|
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CP0857941
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N4-(4-fluorophenyl)-N6,N6-dimethyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
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C13H13FN6
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1
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| 1 |
IC50 = 4027 nM
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CP0509307
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N-[3-(4-methylpiperazin-1-yl)phenyl]-N-propan-2-ylbenzamide
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C21H27N3O
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1
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| 1 |
IC50 = 4164 nM
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CP0384562
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ethyl 4-[2-[butyl(methyl)amino]ethylamino]-2,6-dimethylfuro[2,3-d]pyrimidine-5-carboxylate
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C18H28N4O3
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1
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| 1 |
IC50 = 4169 nM
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CP0399041
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N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
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C13H20N2O2S
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1
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| 1 |
IC50 = 4260 nM
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CP0857562
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N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-1-cyclopentyl-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
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C25H39Cl4N5O
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1
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| 1 |
IC50 = 4375 nM
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CP0917184
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ethyl 4-(2-(dimethylamino)ethylamino)-2-methyl-7H-cyclopenta[d]pyrimidine-5-carboxylate
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C15H22N4O2
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1
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| 1 |
IC50 = 4482 nM
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CP0377207
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N-[2-(4-methylpiperazin-1-yl)phenyl]-N-propan-2-ylnaphthalene-2-sulfonamide
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C24H29N3O2S
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1
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| 1 |
IC50 = 4638 nM
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CP0485075
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N-[2-[(1-ethylpyrrolidin-2-yl)methylamino]-4-methylquinolin-6-yl]-2-[4-(trifluoromethoxy)phenoxy]acetamide
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C26H29F3N4O3
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1
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| 1 |
IC50 = 4700 nM
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CP0510369
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N-(cyclopropylmethyl)-N-[3-[4-(4-fluorophenyl)piperazin-1-yl]propyl]quinoline-8-sulfonamide
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C26H31FN4O2S
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1
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| 1 |
IC50 = 4755 nM
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CP0501817
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4-Methoxy-N-{3-[4-(p-fluorophenyl)-piperazin-1-yl]-propyl}-benzenesulfonamide
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C20H26FN3O3S
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1
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| 1 |
IC50 = 4886 nM
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CP0051598
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(1-Ethyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl)-methyl-amine
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C12H13N5
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1
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| 1 |
IC50 = 5110 nM
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CP0377208
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N-[3-(4-methylpiperazin-1-yl)phenyl]naphthalene-2-sulfonamide
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C21H23N3O2S
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1
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| 1 |
IC50 = 5147 nM
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CP0861030
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1,2-Dimethyl-5-phenyl-N-(3-(4-(pyridin-4-yl)piperazin-1-yl)propyl)-1H-pyrrole-3-carboxamide dihydrochloride
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C25H33Cl2N5O
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1
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| 1 |
IC50 = 5257 nM
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CP0384560
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N-[2-(4-methylpiperazine-1-carbonyl)-1-benzofuran-3-yl]acetamide
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C16H19N3O3
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1
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| 1 |
IC50 = 5294 nM
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CP0373949
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6-N,6-N-diethyl-4-N-(3-methoxyphenyl)-1-methylpyrazolo[3,4-d]pyrimidine-4,6-diamine
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C17H22N6O
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1
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| 1 |
IC50 = 5422 nM
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CP0860610
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N6,N6-diethyl-N4-(3-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
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C16H20N6O
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1
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| 1 |
IC50 = 5422 nM
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CP0383570
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N-[(2-ethyl-1,3-dihydroisoindol-4-yl)methyl]-3-fluoro-4-methylaniline
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C18H21FN2
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1
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| 1 |
IC50 = 5627 nM
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CP0466898
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(E)-N-[2-(2-Dimethylamino-ethylamino)-4-methyl-quinolin-6-yl]-3-(4-trifluoromethoxy-phenyl)-acrylamide
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C24H25F3N4O2
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1
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| 1 |
IC50 = 5700 nM
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CP0470611
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6-N-cyclohexyl-4-N-(4-fluorophenyl)-1-methylpyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
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C18H21FN6
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1
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| 1 |
IC50 = 5713 nM
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CP0848759
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N6-cyclohexyl-N4-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
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C17H19FN6
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1
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| 1 |
IC50 = 5713 nM
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CP0467639
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N-methyl-N-(1-methylpiperidin-4-yl)-4-(trifluoromethyl)benzenesulfonamide
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C14H19F3N2O2S
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1
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| 1 |
IC50 = 5733 nM
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CP0383572
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4-N-(4-fluorophenyl)-1-methyl-6-N-[(4-methylphenyl)methyl]pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
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C20H19FN6
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1
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| 1 |
IC50 = 5833 nM
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CP0848760
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N4-(4-fluorophenyl)-N6-(4-methylbenzyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
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C19H17FN6
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1
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| 1 |
IC50 = 5833 nM
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CP0378081
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2-(2,4-Dichloro-phenoxy)-N-{2-[(2-hydroxy-ethyl)-methyl-amino]-4-methyl-quinolin-6-yl}-acetamide
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C21H21Cl2N3O3
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1
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| 1 |
IC50 = 5900 nM
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CP0493711
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N,1-dimethyl-N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]indole-3-carboxamide
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C22H20N4O2
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1
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| 1 |
IC50 = 6369 nM
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CP0516368
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4-Chloro-N-isopropyl-N-[3-(4-methyl-piperazin-1-yl)-phenyl]-benzamide
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C21H26ClN3O
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1
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| 1 |
IC50 = 7702 nM
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CP0374017
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4-N-(4-fluorophenyl)-6-N,1-dimethylpyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
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C13H13FN6
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1
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| 1 |
IC50 = 7787 nM
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CP0857445
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N4-(4-fluorophenyl)-N6-methyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
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C12H11FN6
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1
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| 1 |
IC50 = 7787 nM
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CP0371727
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N-(cyclopropylmethyl)-N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]quinoline-8-sulfonamide
Show/Hide
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C27H34N4O3S
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1
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| 1 |
IC50 = 8312 nM
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CP0383573
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4-N-(3,4-dimethylphenyl)-6-N,6-N-diethyl-1-methylpyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
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C18H24N6
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1
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| 1 |
IC50 = 8491 nM
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CP0848758
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N4-(3,4-dimethylphenyl)-N6,N6-diethyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
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C17H22N6
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1
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| 1 |
IC50 = 8491 nM
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CP0507595
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4-methyl-N-((5-methylbenzo[d]isoxazol-3-yl)methyl)piperazine-1-carboxamide
Show/Hide
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C15H20N4O2
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1
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| 1 |
IC50 = 8928 nM
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CP0479997
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N-[3-(3-methylphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]propanamide
Show/Hide
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C13H13N5OS
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1
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| 1 |
IC50 = 9223 nM
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CP0512260
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N-methyl-N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-1H-indole-3-carboxamide
Show/Hide
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C21H18N4O2
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1
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| 1 |
IC50 = 9441 nM
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CP0233824
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4-Methoxy-N-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-benzenesulfonamide
Show/Hide
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C21H29N3O4S
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1
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| 1 |
IC50 = 9665 nM
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CP0446449
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N-(4-methyl-2-morpholin-4-ylquinolin-6-yl)-2-[4-(trifluoromethoxy)phenoxy]acetamide
Show/Hide
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C23H22F3N3O4
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1
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| 1 |
IC50 > 10000 nM
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CP0485076
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(E)-N-{2-[(2-Hydroxy-ethyl)-methyl-amino]-4-methyl-quinolin-6-yl}-3-(4-trifluoromethoxy-phenyl)-acrylamide
Show/Hide
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C23H22F3N3O3
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1
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| 1 |
IC50 > 10000 nM
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CP0373166
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4-chloro-3-methyl-N-(2-morpholinoethyl)isoxazole-5-carboxamide
Show/Hide
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C11H16ClN3O3
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1
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| 1 |
IC50 > 10000 nM
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CP0373950
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4-N-(4-fluorophenyl)-6-N-(3-methoxypropyl)-1-methylpyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
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C16H19FN6O
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1
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| 1 |
IC50 > 10000 nM
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CP0374081
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4-N-(4-fluorophenyl)-6-N-(2-methoxyethyl)-1-methylpyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
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C15H17FN6O
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1
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| 1 |
IC50 > 10000 nM
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CP0374083
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4-N-(4-fluorophenyl)-1-methyl-6-N-prop-2-enylpyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
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C15H15FN6
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1
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| 1 |
IC50 > 10000 nM
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CP0383571
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2-cyclopropyl-7-((5-methyl-4H-1,2,4-triazol-3-ylthio)methyl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one
Show/Hide
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C12H12N6OS2
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1
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| 1 |
IC50 > 10000 nM
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CP0384563
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N-[2-(cyclohexen-1-yl)ethyl]-1-ethyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-amine
Show/Hide
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C19H23N5
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1
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| 1 |
IC50 > 10000 nM
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CP0384568
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3-(4-(4-fluorophenylamino)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylamino)propan-1-ol
Show/Hide
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C15H17FN6O
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1
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| 1 |
IC50 > 10000 nM
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CP0385573
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3-methyl-N-(2-morpholinoethyl)isoxazole-5-carboxamide
Show/Hide
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C11H17N3O3
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1
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| 1 |
IC50 > 10000 nM
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CP0385574
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8-methyl-N-(4-methylphenethyl)tetrazolo[1,5-a]quinolin-4-amine
Show/Hide
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C18H18N6
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1
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| 1 |
IC50 > 10000 nM
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CP0418207
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2-(1-(3-methylbenzyl)-3-oxopiperazin-2-yl)acetic acid
Show/Hide
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C14H18N2O3
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1
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| 1 |
IC50 > 10000 nM
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CP0418208
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(S)-7-methoxy-1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid
Show/Hide
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C14H16N2O3
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1
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| 1 |
IC50 > 10000 nM
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CP0418210
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N-(2-methylphenyl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine-2-carboxamide
Show/Hide
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C16H23N3O
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1
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| 1 |
IC50 > 10000 nM
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CP0450625
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1-(2-(diethylamino)ethyl)-N-(pyridin-4-ylmethyl)-1H-benzo[d]imidazol-2-amine
Show/Hide
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C19H25N5
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1
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| 1 |
IC50 > 10000 nM
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CP0454248
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3-methyl-N-(3-o-tolyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)benzamide
Show/Hide
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C18H15N5OS
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1
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| 1 |
IC50 > 10000 nM
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CP0461508
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N-[2-(dimethylamino)ethyl]-3-pyridin-3-yl-1,2,4-oxadiazole-5-carboxamide
Show/Hide
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C12H15N5O2
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1
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| 1 |
IC50 > 10000 nM
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CP0470612
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6-N-ethyl-4-N-(4-fluorophenyl)-1-methylpyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
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C14H15FN6
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1
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| 1 |
IC50 > 10000 nM
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CP0472036
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8-methyl-N-propyltetrazolo[1,5-a]quinoxalin-4-amine
Show/Hide
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C12H14N6
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1
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| 1 |
IC50 > 10000 nM
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CP0496206
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6-N-cyclopentyl-4-N-(4-fluorophenyl)-1-methylpyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
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C17H19FN6
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1
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| 1 |
IC50 > 10000 nM
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CP0496217
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3-(3,4-dimethylphenyl)-1,4,8-triazaspiro[4.5]dec-3-en-2-one
Show/Hide
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C15H19N3O
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1
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| 1 |
IC50 > 10000 nM
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CP0496218
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8,9-dimethoxy-5,5-dimethyl-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline
Show/Hide
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C16H23NO2
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1
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| 1 |
IC50 > 10000 nM
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CP0496222
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6-N-ethyl-1-methyl-4-N-phenylpyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
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C14H16N6
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1
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| 1 |
IC50 > 10000 nM
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CP0498882
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1,3-dimethyl-5-((2-morpholinoethylamino)methyl)-1H-benzo[d]imidazol-2(3H)-one
Show/Hide
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C16H24N4O2
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1
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| 1 |
IC50 > 10000 nM
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CP0501473
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4-N-(4-fluorophenyl)-1-methyl-6-N-(2-morpholin-4-ylethyl)pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
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C18H22FN7O
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1
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| 1 |
IC50 > 10000 nM
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CP0501474
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3-methyl-N-(2-morpholinoethyl)isoxazolo[5,4-d]pyrimidin-4-amine
Show/Hide
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C12H17N5O2
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1
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| 1 |
IC50 > 10000 nM
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CP0501475
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N-(2-ethylphenyl)-2-(3-oxopiperazin-2-yl)acetamide
Show/Hide
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C14H19N3O2
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1
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| 1 |
IC50 > 10000 nM
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CP0501476
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4,5-Dihydro-thieno[3',2':3,4]benzo[1,2-d]isoxazole-3-carboxylic acid [2-(2-methyl-piperidin-1-yl)-ethyl]-amide
Show/Hide
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C18H23N3O2S
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1
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| 1 |
IC50 > 10000 nM
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CP0504717
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N-[2-(4-methylpiperazin-1-yl)ethyl]-1H-pyrrolo[3,2-h]quinoline-2-carboxamide
Show/Hide
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C19H23N5O
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1
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| 1 |
IC50 > 10000 nM
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CP0504756
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1-methyl-N4-phenyl-N6-propyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
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C15H18N6
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1
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| 1 |
IC50 > 10000 nM
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CP0507596
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ethyl 6-methyl-4-(2-morpholin-4-ylethylamino)furo[2,3-d]pyrimidine-5-carboxylate
Show/Hide
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C16H22N4O4
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1
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| 1 |
IC50 > 10000 nM
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CP0507597
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3-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-N-(2-morpholinoethyl)-4,5-dihydroisoxazole-5-carboxamide
Show/Hide
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C16H25N5O3
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1
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| 1 |
IC50 > 10000 nM
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CP0510950
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N-(3,4-dimethylphenyl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine-2-carboxamide
Show/Hide
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C17H25N3O
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1
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| 1 |
IC50 > 10000 nM
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CP0499093
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N-pyridin-3-yl-1H-indole-3-carboxamide
Show/Hide
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C14H11N3O
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1
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| 1 |
IC50 > 10000 nM
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CP0514709
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N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-1H-benzimidazole-2-carboxamide
Show/Hide
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C19H15N5O2
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1
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| 1 |
IC50 > 10000 nM
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CP0398638
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N-propan-2-yl-N-(6-pyridin-3-yloxypyridin-3-yl)naphthalene-2-sulfonamide
Show/Hide
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C23H21N3O3S
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1
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| 1 |
IC50 > 10000 nM
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CP0417854
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1-Isopropyl-1-[3-(4-methyl-piperazin-1-yl)-phenyl]-3-phenyl-urea
Show/Hide
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C21H28N4O
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1
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| 1 |
IC50 > 10000 nM
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CP0507955
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Benzyl-isopropyl-[3-(4-methyl-piperazin-1-yl)-phenyl]-amine
Show/Hide
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C21H29N3
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1
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| 1 |
IC50 > 10000 nM
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CP0847162
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rac-N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-fluorophenyl)-5-methyl-2-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C31H36Cl4FN5O2
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1
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| 1 |
IC50 > 10000 nM
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CP0853003
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N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-2,5-dimethyl-1-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C24H39Cl2N5O2
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1
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| 1 |
IC50 > 10000 nM
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CP0853011
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rac-N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(2-fluorophenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C27H36Cl2FN5O2
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1
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| 1 |
IC50 > 10000 nM
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CP0427520
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N-methyl-N-(1-methylpiperidin-4-yl)-4-nitrobenzenesulfonamide
Show/Hide
|
C13H19N3O4S
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1
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| 1 |
IC50 > 10000 nM
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CP0439973
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N-methyl-N-(1-methylpiperidin-4-yl)-4-(trifluoromethoxy)benzenesulfonamide
Show/Hide
|
C14H19F3N2O3S
|
1
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| 1 |
IC50 > 10000 nM
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CP0439974
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4-cyano-N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
Show/Hide
|
C14H19N3O2S
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1
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| 1 |
IC50 > 10000 nM
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CP0452120
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2-fluoro-N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
Show/Hide
|
C13H19FN2O2S
|
1
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| 1 |
IC50 > 10000 nM
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CP0496233
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N-methyl-N-(1-methylpiperidin-4-yl)-1-benzothiophene-7-sulfonamide
Show/Hide
|
C15H20N2O2S2
|
1
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| 1 |
IC50 > 10000 nM
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CP0507778
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5-chloro-6-(4-methylpiperazin-1-yl)-N-[3-pyridin-3-yl-5-(trifluoromethoxy)phenyl]-2,3-dihydroindole-1-carboxamide
Show/Hide
|
C26H25ClF3N5O2
|
1
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| 1 |
IC50 = 10000 nM
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CP0846050
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N6-allyl-N4-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
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C14H13FN6
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1
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| 1 |
IC50 > 10000 nM
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CP0848761
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N6-cyclopentyl-N4-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
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C16H17FN6
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1
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| 1 |
IC50 > 10000 nM
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CP0848762
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N6-ethyl-N4-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
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C13H13FN6
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1
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| 1 |
IC50 > 10000 nM
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CP0856416
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N,N-Dimethyl-2-(4-methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine hydrochloride
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C15H27ClN6
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1
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| 1 |
IC50 > 10000 nM
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CP0857446
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N4-(4-fluorophenyl)-N6-(2-morpholinoethyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
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C17H20FN7O
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1
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| 1 |
IC50 > 10000 nM
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CP0857447
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3-(4-(4-fluorophenylamino)-1H-pyrazolo[3,4-d]pyrimidin-6-ylamino)propan-1-ol
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C14H15FN6O
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1
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| 1 |
IC50 > 10000 nM
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CP0857936
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2-(4-methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine hydrochloride
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C13H22ClN5
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1
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| 1 |
IC50 > 10000 nM
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CP0857940
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2-(4-Methylpiperazin-1-yl)-N-ethyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine hydrochloride
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C15H27ClN6
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1
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| 1 |
IC50 > 10000 nM
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CP0857949
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4-(2-(4-Methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-yl)thiomorpholine hydrochloride
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C17H29ClN6S
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1
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| 1 |
IC50 > 10000 nM
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CP0864804
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N-Methyl-2-(4-methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine hydrochloride
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C14H25ClN6
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1
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| 1 |
IC50 > 10000 nM
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CP0864839
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N6-ethyl-N4-phenyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
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C13H14N6
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1
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| 1 |
IC50 > 10000 nM
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CP0876523
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N4-(4-fluorophenyl)-N6-(3-methoxypropyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
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C15H17FN6O
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1
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| 1 |
IC50 > 10000 nM
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CP0876524
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N4-(4-fluorophenyl)-N6-(2-methoxyethyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
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C14H15FN6O
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1
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| 1 |
IC50 > 10000 nM
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CP0912127
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N4-phenyl-N6-propyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
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C14H16N6
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1
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| 1 |
IC50 > 10000 nM
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CP0919956
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N,N-Diethyl-2-(4-methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine hydrochloride
Show/Hide
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C17H31ClN6
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1
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| 1 |
IC50 > 10000 nM
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CP0946361
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4-Methoxy-2-(4-methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine hydrochloride
Show/Hide
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C14H24ClN5O
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1
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| 1 |
IC50 > 10000 nM
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CP0946362
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4-(2-(4-Methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-yl)morpholine hydrochloride
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C17H29ClN6O
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1
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| 1 |
IC50 > 10000 nM
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CP0474740
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N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropyl]-2,5-dimethyl-1-propylimidazole-4-carboxamide
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C24H37N5O2
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1
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| 1 |
IC50 > 10000 nM
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CP0871153
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N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-1-isobutyl-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
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C25H41Cl2N5O
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1
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| 1 |
IC50 = 10140 nM
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CP0409810
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N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-2,5-dimethyl-1-(2-methylpropyl)imidazole-4-carboxamide
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C25H39N5O
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1
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| 1 |
IC50 = 10140 nM
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CP0456423
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(E)-N-[2-(2-Dimethylamino-1-methyl-ethylamino)-4-methyl-quinolin-6-yl]-3-(4-trifluoromethoxy-phenyl)-acrylamide
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C25H27F3N4O2
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1
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| 1 |
IC50 = 18000 nM
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CP0392031
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7-fluoro-N-[3-pyridin-3-yl-5-(trifluoromethoxy)phenyl]-2,3-dihydroindole-1-carboxamide
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C21H15F4N3O2
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1
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| 1 |
IC50 > 40000 nM
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CP0487912
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6-(4-methylpiperazin-1-yl)-N-[3-pyridin-3-yl-5-(trifluoromethoxy)phenyl]-2,3-dihydroindole-1-carboxamide
Show/Hide
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C26H26F3N5O2
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1
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| 1 |
IC50 > 40000 nM
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CP0430935
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8-[5-(2-methoxy-5-phenylphenyl)-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione
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C25H29N3O4
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1
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| 1 |
Ki = 0.1995 nM
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CP0492700
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8-[5-(4,5-dichloro-2-methoxyphenyl)-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione
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C19H23Cl2N3O4
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1
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| 1 |
Ki = 0.2512 nM
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CP0150364
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2,8-Dimethyl-5-((Z)-styryl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
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C21H22N2
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1
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| 1 |
Ki = 0.4786 nM
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CP0409693
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8,9-Dichloro-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoxaline
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C11H13Cl2N3
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2
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| 1 |
Ki = 1 nM
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| 2 |
Ki = 18 nM
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CP0237538
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2,8-Dimethyl-5-phenethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
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C21H24N2
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1
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| 1 |
Ki = 1.202 nM
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CP0432270
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N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]-4-propan-2-ylbenzenesulfonamide
Show/Hide
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C29H38N4O7S
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1
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| 1 |
Ki = 1.585 nM
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CP0448988
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N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]-4-(trifluoromethoxy)benzenesulfonamide
Show/Hide
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C27H31F3N4O8S
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1
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| 1 |
Ki = 1.585 nM
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CP0353494
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2,8-Dimethyl-5-(2-p-tolylethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
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C22H26N2
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1
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| 1 |
Ki = 1.585 nM
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CP0031743
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1H-imidazo[4,5-c]pyridine derivative
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C18H26N4O2S
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1
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| 1 |
Ki = 1.995 nM
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CP0055944
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N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)-1-oxopentyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)benzenesulfonamide
Show/Hide
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C27H31F3N4O7S
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1
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| 1 |
Ki = 1.995 nM
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CP0196718
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(R)-8,9-Dichloro-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,2-a]quinoxalin-5-one
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C11H11Cl2N3O
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2
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| 1 |
Ki = 3 nM
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| 2 |
Ki = 32 nM
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CP0375150
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8-[5-(2,5-dimethoxyphenyl)-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione
Show/Hide
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C20H27N3O5
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1
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| 1 |
Ki = 3.162 nM
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CP0437463
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8-[5-(5-chloro-2-methoxyphenyl)-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione
Show/Hide
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C19H24ClN3O4
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1
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| 1 |
Ki = 3.981 nM
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CP0418829
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8,9-Dichloro-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,2-a]quinoxalin-5-one
Show/Hide
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C11H11Cl2N3O
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2
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| 1 |
Ki = 4 nM
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| 2 |
Ki = 58 nM
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CP0409618
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4-chloro-N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]benzenesulfonamide
Show/Hide
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C26H31ClN4O7S
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1
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| 1 |
Ki = 5.012 nM
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CP0416040
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8-[5-(4-chloro-2-methoxyphenyl)-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione
Show/Hide
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C19H24ClN3O4
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1
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| 1 |
Ki = 6.31 nM
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CP0511112
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(R)-8,9-Dichloro-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoxaline
Show/Hide
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C11H13Cl2N3
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2
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| 1 |
Ki = 7 nM
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| 2 |
Ki = 88 nM
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CP0404364
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4-cyano-N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]benzenesulfonamide
Show/Hide
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C27H31N5O7S
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1
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| 1 |
Ki = 7.943 nM
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CP0408598
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(S)-8,9-Dichloro-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoxaline
Show/Hide
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C11H13Cl2N3
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2
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| 1 |
Ki = 8 nM
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| 2 |
Ki = 61 nM
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CP0515912
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9-Chloro-8-trifluoromethyl-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,2-a]quinoxalin-5-one
Show/Hide
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C12H11ClF3N3O
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2
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| 1 |
Ki = 9 nM
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| 2 |
Ki = 84 nM
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CP0376691
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N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]-4-methylbenzenesulfonamide
Show/Hide
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C27H34N4O7S
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1
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| 1 |
Ki = 10 nM
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CP0383941
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8-[5-(2,4-dimethoxy-5-phenylphenyl)-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione
Show/Hide
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C26H31N3O5
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1
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| 1 |
Ki = 10 nM
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CP0498411
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N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]-4-fluorobenzenesulfonamide
Show/Hide
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C26H31FN4O7S
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1
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| 1 |
Ki = 10 nM
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CP0380471
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(R)-9-Chloro-8-trifluoromethyl-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoxaline
Show/Hide
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C12H13ClF3N3
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2
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| 1 |
Ki = 17 nM
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| 2 |
Ki = 92 nM
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CP0430675
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N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]-4-methoxybenzenesulfonamide
Show/Hide
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C27H34N4O8S
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1
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| 1 |
Ki = 19.95 nM
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CP0380573
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7,9-Dichloro-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,2-a]quinoxalin-5-one
Show/Hide
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C11H11Cl2N3O
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2
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| 1 |
Ki = 20 nM
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| 2 |
Ki = 368 nM
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CP0467130
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(R)-9-Chloro-8-trifluoromethyl-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,2-a]quinoxalin-5-one
Show/Hide
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C12H11ClF3N3O
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2
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| 1 |
Ki = 25 nM
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| 2 |
Ki = 160 nM
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CP0384762
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N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]benzenesulfonamide
Show/Hide
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C26H32N4O7S
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1
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| 1 |
Ki = 31.62 nM
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CP0424572
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(R)-9-Chloro-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,2-a]quinoxalin-5-one
Show/Hide
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C11H12ClN3O
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2
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| 1 |
Ki = 34 nM
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| 2 |
Ki = 238 nM
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CP0430131
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4-acetyl-N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]benzenesulfonamide
Show/Hide
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C28H34N4O8S
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1
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| 1 |
Ki = 39.81 nM
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CP0502718
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N-[4-[[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]sulfamoyl]phenyl]acetamide
Show/Hide
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C28H35N5O8S
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1
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| 1 |
Ki = 39.81 nM
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CP0492835
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3-chloro-N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]benzenesulfonamide
Show/Hide
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C26H31ClN4O7S
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1
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| 1 |
Ki = 50.12 nM
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CP0439313
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(S)-8,9-Dichloro-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,2-a]quinoxalin-5-one
Show/Hide
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C11H11Cl2N3O
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2
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| 1 |
Ki = 66 nM
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| 2 |
Ki = 285 nM
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CP0017601
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2,8-dimethyl-5-[2-(6-methylpyridin-3-yl)ethyl]-3,4-dihydro-1H-pyrido[4,3-b]indole
Show/Hide
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C21H25N3
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1
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| 1 |
Ki = 75.86 nM
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CP0432240
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4-N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]benzene-1,4-disulfonamide
Show/Hide
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C26H33N5O9S2
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1
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| 1 |
Ki = 79.43 nM
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CP0488167
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8,9-Difluoro-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,2-a]quinoxalin-5-one
Show/Hide
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C11H11F2N3O
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2
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| 1 |
Ki = 91 nM
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| 2 |
Ki = 1800 nM
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CP0445660
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2-chloro-N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]benzenesulfonamide
Show/Hide
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C26H31ClN4O7S
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1
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| 1 |
Ki = 398.11 nM
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CP0503510
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(S)-9-Chloro-8-trifluoromethyl-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,2-a]quinoxalin-5-one
Show/Hide
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C12H11ClF3N3O
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2
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| 1 |
Ki = 516 nM
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| 2 |
Ki = 3600 nM
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CP0040671
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8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Show/Hide
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C23H26FN3O2
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1
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| 1 |
Ki = 630.96 nM
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CP0408680
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9,10-Dichloro-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,2-a]quinoxalin-5-one
Show/Hide
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C11H11Cl2N3O
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2
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| 1 |
Ki = 1000 nM
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| 2 |
Ki = 1700 nM
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CP0430300
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8-Benzoyl-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,2-a]quinoxalin-5-one
Show/Hide
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C18H17N3O2
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2
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| 1 |
Ki = 2150 nM
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| 2 |
Ki = 9200 nM
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CP0497328
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8-[5-(2-methoxyphenyl)-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione
Show/Hide
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C19H25N3O4
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1
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| 1 |
Ki < 10000 nM
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