Brief Information of the Compound and Protein
Compound Name
2-(2-methylbenzyl)-6,7,8,9-tetrahydro-5H-pyrimido[5,4-d]azepine
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PubChem ID
CID: 54587668
Canonical SMILES
Cc1ccccc1Cc1ncc2CCNCCc2n1
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Compound Formula C16H19N3
Compound Structure
Protein Name
5-hydroxytryptamine receptor 2C
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P28335
Gene Name
HTR2C
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 330 nM
   TI
   LI
   LO
   TS
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
Ki = 305 nM
   TI
   LI
   LO
   TS