Brief Information of the Compound and Protein
Compound Name
5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid (3-pyridin-3-yl-phenyl)-amide
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PubChem ID
CID: 9931534
SID: 14904381
Canonical SMILES
COc1cc2CCN(C(=O)Nc3cccc(c3)-c3cccnc3)c2cc1C(F)(F)F
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Compound Formula C22H18F3N3O2
Compound Structure
Protein Name
5-hydroxytryptamine receptor 2C
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P28335
Gene Name
HTR2C
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 7 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 1 nM
   TI
   LI
   LO
   TS